DE19681353T1 - Metaboliten der Ginseng-Saponine durch menschliche Darmbakterien und deren Zubereitung als Antikrebsmittel - Google Patents
Metaboliten der Ginseng-Saponine durch menschliche Darmbakterien und deren Zubereitung als AntikrebsmittelInfo
- Publication number
- DE19681353T1 DE19681353T1 DE19681353T DE19681353T DE19681353T1 DE 19681353 T1 DE19681353 T1 DE 19681353T1 DE 19681353 T DE19681353 T DE 19681353T DE 19681353 T DE19681353 T DE 19681353T DE 19681353 T1 DE19681353 T1 DE 19681353T1
- Authority
- DE
- Germany
- Prior art keywords
- metabolites
- preparation
- cancer agents
- human gut
- gut bacteria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J17/005—Glycosides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019960004217A KR0164266B1 (ko) | 1996-02-22 | 1996-02-22 | 인삼사포닌 장내세균 대사물 및 이를 유효성분으로하는 제암제제 |
KR1996/4217 | 1996-02-22 | ||
PCT/KR1996/000281 WO1997031013A1 (en) | 1996-02-22 | 1996-12-31 | Metabolites of ginseng saponins by human intestinal bacteria and its preparation for an anticancer |
Publications (2)
Publication Number | Publication Date |
---|---|
DE19681353T1 true DE19681353T1 (de) | 1998-04-16 |
DE19681353B4 DE19681353B4 (de) | 2004-09-30 |
Family
ID=19451583
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19681353T Expired - Lifetime DE19681353B4 (de) | 1996-02-22 | 1996-12-31 | Metabolit der Ginseng-Saponine durch menschliche Darmbakterien und seine Zube reitung als Antikrebsmittel |
Country Status (6)
Country | Link |
---|---|
US (1) | US5919770A (de) |
KR (1) | KR0164266B1 (de) |
CN (1) | CN1182433A (de) |
CA (1) | CA2218724C (de) |
DE (1) | DE19681353B4 (de) |
WO (1) | WO1997031013A1 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1307473A (zh) * | 1998-05-19 | 2001-08-08 | 研究发展基金会 | 三萜组合物和它们的使用方法 |
US20060148732A1 (en) * | 2000-11-17 | 2006-07-06 | Gutterman Jordan U | Inhibition of NF-kappaB by triterpene compositions |
US6949523B2 (en) | 2001-07-24 | 2005-09-27 | Panagin Pharmaceuticals, Inc. | Aglycon dammarane sapogenins, their use as anti-cancer agents, and a process for producing same |
US6888014B2 (en) * | 2001-07-24 | 2005-05-03 | Panagin Pharmaceuticals Inc. | Dammarane sapogenins, their use as anti-cancer agents, and a process for producing same |
CN1336232A (zh) * | 2001-09-03 | 2002-02-20 | 李永忠 | 一种纯生物增寿制品 |
US20030092638A1 (en) * | 2001-09-21 | 2003-05-15 | Dong Huang | Protopanaxadiol and protopanaxatriol and their use as anti-cancer agents |
KR100835864B1 (ko) * | 2002-05-27 | 2008-06-09 | (주)아모레퍼시픽 | 인삼사포닌 대사 산물을 유효 성분으로 한 미세 유화 입자 및 그 제조방법, 이를 함유한 피부 노화방지용 화장료 조성물 |
KR100465977B1 (ko) * | 2002-01-05 | 2005-01-13 | 주식회사 태평양 | 나노유화기술에 의한 화합물 k를 함유하는 미세 유화 입자 및 이를 사용한 피부 외용제 조성물 |
JP4549625B2 (ja) * | 2002-01-05 | 2010-09-22 | 株式會社アモーレパシフィック | 人参サポニン代謝産物を有効成分とする微細乳化粒子及びその製造方法、並びにこれを含有する皮膚老化防止用の化粧料組成物 |
WO2003086439A1 (en) * | 2002-04-08 | 2003-10-23 | Ginseng Science Inc. | Novel use of the extract of processed panax genus plant and saponin compound isolated therefrom |
WO2003086438A1 (en) * | 2002-04-08 | 2003-10-23 | Ginseng Science Inc. | Extract of processed panax genus plant, the preparation method thereof, and compositions containing the same |
CN1508146A (zh) * | 2002-12-13 | 2004-06-30 | 中国科学院大连化学物理研究所 | 一种新型抗肿瘤人参皂苷 |
WO2004056371A1 (en) * | 2002-12-19 | 2004-07-08 | Panagin Pharmaceuticals Inc. | Use of aglycon protopanaxatriol in cancer therapy |
KR100485326B1 (ko) * | 2002-12-26 | 2005-04-27 | 주식회사 태평양 | 진세노사이드 화합물 k로 이루어진 히알루론산 생성촉진제 |
KR100654172B1 (ko) * | 2005-05-27 | 2006-12-06 | 주식회사 비티진 | 효소반응에 의한 진세노사이드 Mc 및 진세노사이드Mc-1의 제조방법 |
BRPI0715073A8 (pt) * | 2006-08-03 | 2018-04-10 | Oncology Res International Limited | métodos e composições para inibir a angiogênese |
US20120263806A1 (en) * | 2007-05-16 | 2012-10-18 | Miller Sandra | Uses of North American Ginseng Fractions for Treating Leukemia |
EP2510924B1 (de) | 2009-12-08 | 2014-10-08 | IL Hwa Co., Ltd | FESTE DISPERSIONEN MIT 20-O-ß-D-GLUCOPYRANOSYL-20(S)-PROTOPANAXADIOL |
KR102048709B1 (ko) * | 2013-04-24 | 2019-11-27 | (주)아모레퍼시픽 | 진세노사이드 Mc를 함유하는 피부 외용제 조성물 |
KR102020754B1 (ko) * | 2013-05-03 | 2019-09-11 | (주)아모레퍼시픽 | 진세노사이드 y를 함유하는 피부 외용제 조성물 |
US10456436B2 (en) * | 2013-11-04 | 2019-10-29 | Wen Luan Wendy Hsiao | Use of herbal saponins to regulate gut microflora |
US20150126463A1 (en) * | 2013-11-04 | 2015-05-07 | Hong Kong Baptist University | Use of herbal saponins to regulate gut microflora |
US20180185399A1 (en) * | 2015-07-03 | 2018-07-05 | Zhejiang Hisun Pharmaceutical Co., Ltd. | Ginsenoside c-k oral solid preparation and preparation method thereof |
WO2020032448A1 (ko) * | 2018-08-06 | 2020-02-13 | 고려대학교 산학협력단 | 진세노사이드 mc 또는 mc1을 포함하는 대사성 질환 예방 또는 치료용 조성물 |
CN111053782A (zh) * | 2018-10-17 | 2020-04-24 | 株式会社爱茉莉太平洋 | 包含新型人参皂苷的组合物 |
CN115068490A (zh) * | 2022-06-23 | 2022-09-20 | 四川大学 | 人参皂苷ck在制备脓肿分枝杆菌或/和结核分枝杆菌的抑菌剂中的应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5857399A (ja) * | 1981-10-01 | 1983-04-05 | Osaka Chem Lab | ニンジンサポニン、その分離法及び製造法並びに用途 |
JPS6428759A (en) * | 1987-07-24 | 1989-01-31 | Hitachi Ltd | Memory protecting system |
-
1996
- 1996-02-22 KR KR1019960004217A patent/KR0164266B1/ko not_active IP Right Cessation
- 1996-12-31 CA CA002218724A patent/CA2218724C/en not_active Expired - Lifetime
- 1996-12-31 DE DE19681353T patent/DE19681353B4/de not_active Expired - Lifetime
- 1996-12-31 CN CN96193431A patent/CN1182433A/zh active Pending
- 1996-12-31 WO PCT/KR1996/000281 patent/WO1997031013A1/en active Application Filing
- 1996-12-31 US US08/945,422 patent/US5919770A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1997031013A1 (en) | 1997-08-28 |
US5919770A (en) | 1999-07-06 |
KR970061909A (ko) | 1997-09-12 |
CA2218724A1 (en) | 1997-08-28 |
CA2218724C (en) | 2001-11-06 |
DE19681353B4 (de) | 2004-09-30 |
KR0164266B1 (ko) | 1999-01-15 |
CN1182433A (zh) | 1998-05-20 |
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Legal Events
Date | Code | Title | Description |
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8110 | Request for examination paragraph 44 | ||
8607 | Notification of search results after publication | ||
8172 | Supplementary division/partition in: |
Ref document number: 19655311 Country of ref document: DE Kind code of ref document: P |
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8328 | Change in the person/name/address of the agent |
Representative=s name: BOECK, TAPPE, KIRSCHNER RECHTSANWAELTE PATENTANWAELTE |
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8364 | No opposition during term of opposition | ||
8381 | Inventor (new situation) |
Inventor name: HIDEO, HASEGAWA, TOKIO/TOKYO, JP Inventor name: SUNG, JONG HWAN, GURI, KYONGGI, KR Inventor name: SATOSHI, MATSUMIYA, TOKIO/TOKYO, JP Inventor name: MASAMORI, UCHIYAMA, TOKIO/TOKYO, JP Inventor name: HUH, JAE DOO, GURI, KYONGGI, KR |
|
R071 | Expiry of right |