DE19608791A1 - Verfahren zur Herstellung von fluorierten Aromaten und fluorierten stickstoffhaltigen Heteroaromaten - Google Patents

Verfahren zur Herstellung von fluorierten Aromaten und fluorierten stickstoffhaltigen Heteroaromaten

Info

Publication number
DE19608791A1
DE19608791A1 DE19608791A DE19608791A DE19608791A1 DE 19608791 A1 DE19608791 A1 DE 19608791A1 DE 19608791 A DE19608791 A DE 19608791A DE 19608791 A DE19608791 A DE 19608791A DE 19608791 A1 DE19608791 A1 DE 19608791A1
Authority
DE
Germany
Prior art keywords
radicals
alkyl
general formula
formula
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19608791A
Other languages
German (de)
English (en)
Inventor
Wolfgang Dr Appel
Sergej Dr Pasenok
Hans-Jerg Dr Kleiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Research and Technologies GmbH and Co KG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Priority to DE19608791A priority Critical patent/DE19608791A1/de
Priority to CN97192773A priority patent/CN1212674A/zh
Priority to JP9531421A priority patent/JP2000506149A/ja
Priority to KR1019980707152A priority patent/KR19990087687A/ko
Priority to PCT/EP1997/000970 priority patent/WO1997032832A1/de
Priority to EP97905116A priority patent/EP0885179A1/de
Priority to CA002248294A priority patent/CA2248294A1/en
Publication of DE19608791A1 publication Critical patent/DE19608791A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B39/00Halogenation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06Preparation of nitro compounds
    • C07C201/12Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19608791A 1996-03-07 1996-03-07 Verfahren zur Herstellung von fluorierten Aromaten und fluorierten stickstoffhaltigen Heteroaromaten Withdrawn DE19608791A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE19608791A DE19608791A1 (de) 1996-03-07 1996-03-07 Verfahren zur Herstellung von fluorierten Aromaten und fluorierten stickstoffhaltigen Heteroaromaten
CN97192773A CN1212674A (zh) 1996-03-07 1997-02-28 制备氟化的芳香化合物和氟化的含氮杂芳香化合物的方法
JP9531421A JP2000506149A (ja) 1996-03-07 1997-02-28 フッ素化芳香族化合物およびフッ素化窒素含有複素環式芳香族化合物の調製法
KR1019980707152A KR19990087687A (ko) 1996-03-07 1997-02-28 플루오르화 방향족 및 플루오르화 질소-함유 헤테로-방향족을제조하는 방법
PCT/EP1997/000970 WO1997032832A1 (de) 1996-03-07 1997-02-28 Verfahren zur herstellung von fluorierten aromaten und fluorierten stickstoffhaltigen heteroaromaten
EP97905116A EP0885179A1 (de) 1996-03-07 1997-02-28 Verfahren zur herstellung von fluorierten aromaten und fluorierten stickstoffhaltigen heteroaromaten
CA002248294A CA2248294A1 (en) 1996-03-07 1997-02-28 Process for producing fluorinated aromatics and fluorinated nitrogen-containing hetero-aromatics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19608791A DE19608791A1 (de) 1996-03-07 1996-03-07 Verfahren zur Herstellung von fluorierten Aromaten und fluorierten stickstoffhaltigen Heteroaromaten

Publications (1)

Publication Number Publication Date
DE19608791A1 true DE19608791A1 (de) 1997-09-11

Family

ID=7787475

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19608791A Withdrawn DE19608791A1 (de) 1996-03-07 1996-03-07 Verfahren zur Herstellung von fluorierten Aromaten und fluorierten stickstoffhaltigen Heteroaromaten

Country Status (7)

Country Link
EP (1) EP0885179A1 (zh)
JP (1) JP2000506149A (zh)
KR (1) KR19990087687A (zh)
CN (1) CN1212674A (zh)
CA (1) CA2248294A1 (zh)
DE (1) DE19608791A1 (zh)
WO (1) WO1997032832A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1616863A1 (de) * 2004-07-08 2006-01-18 LANXESS Deutschland GmbH Verfahren zur Herstellung Kernfluorierter Aromaten

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69711220T2 (de) 1996-11-22 2002-10-31 Albemarle Corp Halogenaustausch-reaktionen und ihre anwendungen
DE19934594A1 (de) 1999-07-23 2001-01-25 Clariant Gmbh Tetrakis(pyrrolidino/piperidino) phosphoniumsalze enthaltende Mischungen
NZ533865A (en) 2002-02-12 2006-02-24 Smithkline Beecham Corp Nicotinamide derivates useful as p38 inhibitors
GB0308201D0 (en) 2003-04-09 2003-05-14 Smithkline Beecham Corp Novel compounds
WO2015116904A1 (en) 2014-02-03 2015-08-06 Vitae Pharmaceuticals, Inc. Dihydropyrrolopyridine inhibitors of ror-gamma
ES2715458T7 (es) 2014-10-14 2020-05-28 Vitae Pharmaceuticals Llc Inhibidores de dihidropirrolopiridina de ROR-gamma
US9663515B2 (en) 2014-11-05 2017-05-30 Vitae Pharmaceuticals, Inc. Dihydropyrrolopyridine inhibitors of ROR-gamma
US9845308B2 (en) 2014-11-05 2017-12-19 Vitae Pharmaceuticals, Inc. Isoindoline inhibitors of ROR-gamma
WO2017024018A1 (en) 2015-08-05 2017-02-09 Vitae Pharmaceuticals, Inc. Modulators of ror-gamma
KR20180086221A (ko) 2015-11-20 2018-07-30 비타이 파마슈티컬즈, 인코포레이티드 Ror-감마의 조절물질
TWI757266B (zh) 2016-01-29 2022-03-11 美商維它藥物有限責任公司 ROR-γ調節劑
US9481674B1 (en) 2016-06-10 2016-11-01 Vitae Pharmaceuticals, Inc. Dihydropyrrolopyridine inhibitors of ROR-gamma
US10913739B2 (en) 2017-07-24 2021-02-09 Vitae Pharmaceuticals, LLC (121374) Inhibitors of RORγ
WO2019018975A1 (en) 2017-07-24 2019-01-31 Vitae Pharmaceuticals, Inc. INHIBITORS OF ROR GAMMA
CN115745766B (zh) * 2022-10-27 2024-05-14 兰州康鹏威耳化工有限公司 一种三氟苯甲醛及三氟苄溴的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2525442C3 (de) * 1975-06-07 1978-04-13 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung geminaler Dihalogenide
EP0523671B1 (de) * 1991-07-17 1996-01-17 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Chlorfluornitrobenzolen
US5315043A (en) * 1992-02-05 1994-05-24 E. I. Du Pont De Nemours And Company Aromatic nucleophilic fluorination

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1616863A1 (de) * 2004-07-08 2006-01-18 LANXESS Deutschland GmbH Verfahren zur Herstellung Kernfluorierter Aromaten
US7371861B2 (en) 2004-07-08 2008-05-13 Lanxess Deutschland Gmbh Process for preparing ring-fluorinated aromatics
US7803941B2 (en) 2004-07-08 2010-09-28 Lanxess Deutschland Gmbh Process for preparing ring-fluorinated aromatics

Also Published As

Publication number Publication date
EP0885179A1 (de) 1998-12-23
JP2000506149A (ja) 2000-05-23
CN1212674A (zh) 1999-03-31
KR19990087687A (ko) 1999-12-27
WO1997032832A1 (de) 1997-09-12
CA2248294A1 (en) 1997-09-12

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8127 New person/name/address of the applicant

Owner name: AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG, 6592

8130 Withdrawal