DE185031C - - Google Patents
Info
- Publication number
- DE185031C DE185031C DENDAT185031D DE185031DA DE185031C DE 185031 C DE185031 C DE 185031C DE NDAT185031 D DENDAT185031 D DE NDAT185031D DE 185031D A DE185031D A DE 185031DA DE 185031 C DE185031 C DE 185031C
- Authority
- DE
- Germany
- Prior art keywords
- dry
- mouse
- hydrochloric acid
- bacterial
- bacilli
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 claims description 9
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 7
- 230000003053 immunization Effects 0.000 claims description 5
- 231100000614 poison Toxicity 0.000 claims description 5
- 239000002574 poison Substances 0.000 claims description 5
- 238000002649 immunization Methods 0.000 claims description 4
- 231100000765 toxin Toxicity 0.000 claims description 4
- 239000003053 toxin Substances 0.000 claims description 4
- 108700012359 toxins Proteins 0.000 claims description 4
- 230000001580 bacterial effect Effects 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 241000699666 Mus <mouse, genus> Species 0.000 description 7
- 244000052616 bacterial pathogen Species 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 208000028104 epidemic louse-borne typhus Diseases 0.000 description 3
- 239000002504 physiological saline solution Substances 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 206010061393 typhus Diseases 0.000 description 3
- 108010053187 Diphtheria Toxin Proteins 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 231100000699 Bacterial toxin Toxicity 0.000 description 1
- 238000009631 Broth culture Methods 0.000 description 1
- 102000016607 Diphtheria Toxin Human genes 0.000 description 1
- 108010055044 Tetanus Toxin Proteins 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000000688 bacterial toxin Substances 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000000110 cooling liquid Substances 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 206010013023 diphtheria Diseases 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 231100000566 intoxication Toxicity 0.000 description 1
- 230000035987 intoxication Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 229940118376 tetanus toxin Drugs 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE185031C true DE185031C (enrdf_load_stackoverflow) |
Family
ID=448918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DENDAT185031D Active DE185031C (enrdf_load_stackoverflow) |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE185031C (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT386337B (de) * | 1982-05-26 | 1988-08-10 | Ribi Immunochem Research Inc | Verfahren zur herstellung eines raffinierten, entgifteten endotoxinproduktes |
-
0
- DE DENDAT185031D patent/DE185031C/de active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT386337B (de) * | 1982-05-26 | 1988-08-10 | Ribi Immunochem Research Inc | Verfahren zur herstellung eines raffinierten, entgifteten endotoxinproduktes |
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