DE1695839A1 - Neue Derivate des D-6-Methylergolin(I) und Verfahren zur Herstellung derselben - Google Patents

Neue Derivate des D-6-Methylergolin(I) und Verfahren zur Herstellung derselben

Info

Publication number
DE1695839A1
DE1695839A1 DE19681695839 DE1695839A DE1695839A1 DE 1695839 A1 DE1695839 A1 DE 1695839A1 DE 19681695839 DE19681695839 DE 19681695839 DE 1695839 A DE1695839 A DE 1695839A DE 1695839 A1 DE1695839 A1 DE 1695839A1
Authority
DE
Germany
Prior art keywords
methyl
ergolin
acid
ylacetic acid
transferred
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19681695839
Other languages
German (de)
English (en)
Inventor
Norbert Dr Kucharczyk
Miroslav Dr-Ing Semonsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spofa Vereinigte Pharma Werke
Original Assignee
Spofa Vereinigte Pharma Werke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Vereinigte Pharma Werke filed Critical Spofa Vereinigte Pharma Werke
Publication of DE1695839A1 publication Critical patent/DE1695839A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19681695839 1967-03-16 1968-03-15 Neue Derivate des D-6-Methylergolin(I) und Verfahren zur Herstellung derselben Pending DE1695839A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CS192167 1967-03-16
CS192067 1967-03-16
CS192267 1967-03-16

Publications (1)

Publication Number Publication Date
DE1695839A1 true DE1695839A1 (de) 1971-05-13

Family

ID=27179353

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19681695839 Pending DE1695839A1 (de) 1967-03-16 1968-03-15 Neue Derivate des D-6-Methylergolin(I) und Verfahren zur Herstellung derselben

Country Status (11)

Country Link
US (1) US3732231A (en, 2012)
AT (2) AT293628B (en, 2012)
BE (1) BE712054A (en, 2012)
CH (1) CH507248A (en, 2012)
DE (1) DE1695839A1 (en, 2012)
DK (1) DK124080B (en, 2012)
FI (1) FI48080C (en, 2012)
FR (1) FR1556791A (en, 2012)
GB (1) GB1199233A (en, 2012)
NL (1) NL155831B (en, 2012)
SE (1) SE341853B (en, 2012)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920664A (en) * 1972-07-21 1975-11-18 Lilly Co Eli D-2-halo-6-alkyl-8-substituted ergolines and related compounds
NL7400790A (en, 2012) * 1973-02-02 1974-08-06
US3901894A (en) * 1974-06-06 1975-08-26 Lilly Co Eli 8-thiomethylergolines
GB1517971A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 8alpha-substituted ergoline i derivatives
US4348392A (en) * 1974-07-19 1982-09-07 Sandoz Ltd. 8α-Substituted ergoline-I derivatives
US4001242A (en) * 1974-08-02 1977-01-04 Eli Lilly And Company D-6-methyl-8-formyl-10α-alkoxy-8-ergolene
US3904757A (en) * 1974-08-08 1975-09-09 Lilly Co Eli Treatment of parkinsonism
US3985752A (en) * 1974-12-06 1976-10-12 Eli Lilly And Company 6-Methyl-8-(substituted) methylergolines
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
US3992385A (en) * 1975-01-20 1976-11-16 Eli Lilly And Company 2,3-Dihydroergolines
US4054660A (en) * 1975-04-14 1977-10-18 Eli Lilly And Company Method of inhibiting prolactin
CS188414B1 (en) * 1975-12-12 1979-03-30 Antonin Cerny New d-6-alkyl-8-cyanmethyl ergolines,their salts and method of producing
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
US4098790A (en) * 1976-09-15 1978-07-04 Eli Lilly And Company Ergoline chlorination process
IT1158162B (it) * 1977-12-22 1987-02-18 Sandoz Ag Composizioni farmaceutiche a base di derivati dell'ergolena e dell'ergolina
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
GB2112382B (en) * 1981-11-06 1985-03-06 Erba Farmitalia Ergoline derivatives
GB2120242A (en) * 1982-04-30 1983-11-30 Erba Farmitalia Ergoline derivatives
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
US5728457A (en) * 1994-09-30 1998-03-17 Cornell Research Foundation, Inc. Porous polymeric material with gradients
PL3197429T3 (pl) 2014-09-25 2024-09-30 Boehringer Ingelheim Vetmedica Gmbh Leczenie skojarzone inhibitorami sglt2 i agonistami dopaminy do profilaktyki zaburzeń metabolicznych u zwierząt koniowatych
US9534492B2 (en) * 2014-11-11 2017-01-03 Baker Hughes Incorporated Pressure compensated capacitive micromachined ultrasound transducer for downhole applications

Also Published As

Publication number Publication date
AT288608B (de) 1971-03-10
SE341853B (en, 2012) 1972-01-17
FR1556791A (en, 2012) 1969-02-07
US3732231A (en) 1973-05-08
NL6803759A (en, 2012) 1968-09-17
DK124080B (da) 1972-09-11
NL155831B (nl) 1978-02-15
FI48080C (fi) 1974-06-10
BE712054A (en, 2012) 1968-07-15
FI48080B (en, 2012) 1974-02-28
AT293628B (de) 1971-10-25
GB1199233A (en) 1970-07-15
CH507248A (de) 1971-05-15

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