DE1493692A1 - Verfahren zur Reinigung von synthetisch hergestellten Peptiden - Google Patents

Verfahren zur Reinigung von synthetisch hergestellten Peptiden

Info

Publication number
DE1493692A1
DE1493692A1 DE19651493692 DE1493692A DE1493692A1 DE 1493692 A1 DE1493692 A1 DE 1493692A1 DE 19651493692 DE19651493692 DE 19651493692 DE 1493692 A DE1493692 A DE 1493692A DE 1493692 A1 DE1493692 A1 DE 1493692A1
Authority
DE
Germany
Prior art keywords
peptides
purification
tert
solution
synthetically produced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19651493692
Other languages
German (de)
English (en)
Inventor
Sturm Dr Karl
Geiger Dr Rolf
Siedel Dr Walter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of DE1493692A1 publication Critical patent/DE1493692A1/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/695Corticotropin [ACTH]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Detergent Compositions (AREA)
DE19651493692 1965-01-23 1965-01-23 Verfahren zur Reinigung von synthetisch hergestellten Peptiden Pending DE1493692A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0045044 1965-01-23

Publications (1)

Publication Number Publication Date
DE1493692A1 true DE1493692A1 (de) 1969-10-23

Family

ID=7100315

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19651493692 Pending DE1493692A1 (de) 1965-01-23 1965-01-23 Verfahren zur Reinigung von synthetisch hergestellten Peptiden

Country Status (8)

Country Link
AT (1) AT282080B (el)
BE (1) BE675499A (el)
CH (1) CH456626A (el)
DE (1) DE1493692A1 (el)
FR (1) FR1481080A (el)
GB (1) GB1132264A (el)
NL (1) NL6600574A (el)
SE (1) SE319189B (el)

Also Published As

Publication number Publication date
GB1132264A (en) 1968-10-30
CH456626A (de) 1968-07-31
BE675499A (el) 1966-07-25
NL6600574A (el) 1966-07-25
FR1481080A (fr) 1967-05-19
SE319189B (el) 1970-01-12
AT282080B (de) 1970-06-10

Similar Documents

Publication Publication Date Title
DE2712086C2 (de) N-Acyl-dipeptide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
Bodanszky et al. Synthesis of secretin. I. The protected tetradecapeptide corresponding to sequence 14-27
DE2617646A1 (de) Peptide mit gonadoliberin-wirkung und verfahren zu ihrer herstellung
DE2315271B2 (de) L- Norleucin-13-Motllln, Verfahren zu dessen Herstellung und dasselbe enthaltendes Mittel
DE1493692A1 (de) Verfahren zur Reinigung von synthetisch hergestellten Peptiden
DE3340208C2 (el)
DE2615229C2 (de) Verfahren zur Herstellung und Reinigung von Sekretin
JPS58140024A (ja) セクレチンの精製方法
DE2735515A1 (de) Verwendung von lh-rh-peptiden als antikonzeptive
DE1205546B (de) Verfahren zur Herstellung neuer Dekapeptide
DE2532823A1 (de) Neue polypeptide
CH618959A5 (el)
NO161374B (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive mitomycinanaloger.
DE1954794B2 (de) Peptide mit adrenocorticotroper wirkung und verfahren zu ihrer herstellung
DE68914544T2 (de) Peptid und Wirkstoff gegen Dementia.
Shibata et al. The Partial Resolution of Racemic α-Alanine through the Cobalt (III) Complex of L-Aspartic Acid
DE1443315C3 (de) Cyclisches Polypeptid und Verfahren zu dessen Herstellung und dieses ent haltendes Mittel
EP0188629A1 (de) Hexapeptid
DE2244689C3 (de) Dekapeptid mit der Aminosäuresequenz des Gonadotropin freigebenden Hormons GnRH
DE1917690C3 (de) Verfahren zur Herstellung von Peptiden
DE2727048C2 (de) 8-Norleucyl-ceruletide
AT357279B (de) Verfahren zur herstellung von neuen pyroglutamylverbindungen
DE2023447A1 (de) Insulinderivate und Verfahren zu ihrer Herstellung
DE2243066C3 (de) Verfahren zur Herstellung von (Pyro) glutamyl-histWyl-tryptophyl-seryltyrosyl-glycyl-leucyl-arginyl-prolylglycinamid
Fauchère et al. Hormone‐Receptor Interactions. Synthesis and Conformational Study of cyclo‐l‐Cystathionine