DE142120T1 - Verfahren und apparat zur zaehlung von blutbestandteilen. - Google Patents

Verfahren und apparat zur zaehlung von blutbestandteilen.

Info

Publication number
DE142120T1
DE142120T1 DE198484113376T DE84113376T DE142120T1 DE 142120 T1 DE142120 T1 DE 142120T1 DE 198484113376 T DE198484113376 T DE 198484113376T DE 84113376 T DE84113376 T DE 84113376T DE 142120 T1 DE142120 T1 DE 142120T1
Authority
DE
Germany
Prior art keywords
tube
blood cell
photosensor
blood cells
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE198484113376T
Other languages
German (de)
English (en)
Inventor
Stephen Clark Branford Conn. Wardlaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE142120T1 publication Critical patent/DE142120T1/de
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/05—Investigating sedimentation of particle suspensions in blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G01N2015/045—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G01N2015/045—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
    • G01N2015/047—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis by static multidetectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G01N21/5907—Densitometers
    • G01N2021/5957—Densitometers using an image detector type detector, e.g. CCD
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G01N21/5907—Densitometers
    • G01N2021/5969—Scanning of a tube, a cuvette, a volume of sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)
DE198484113376T 1983-11-07 1984-11-06 Verfahren und apparat zur zaehlung von blutbestandteilen. Pending DE142120T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/549,319 US4558947A (en) 1983-11-07 1983-11-07 Method and apparatus for measuring blood constituent counts

Publications (1)

Publication Number Publication Date
DE142120T1 true DE142120T1 (de) 1986-03-20

Family

ID=24192505

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198484113376T Pending DE142120T1 (de) 1983-11-07 1984-11-06 Verfahren und apparat zur zaehlung von blutbestandteilen.
DE8484113376T Expired - Lifetime DE3481444D1 (de) 1983-11-07 1984-11-06 Verfahren und apparat zur zaehlung von blutbestandteilen.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8484113376T Expired - Lifetime DE3481444D1 (de) 1983-11-07 1984-11-06 Verfahren und apparat zur zaehlung von blutbestandteilen.

Country Status (6)

Country Link
US (1) US4558947A (enExample)
EP (1) EP0142120B1 (enExample)
JP (1) JPS60123764A (enExample)
AT (1) ATE50641T1 (enExample)
BR (1) BR8405557A (enExample)
DE (2) DE142120T1 (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683120A (en) * 1983-10-28 1987-07-28 Gamma Biologicals, Inc. Biological fluid assay system
US4837160A (en) * 1983-10-28 1989-06-06 Gamma Biologicals, Inc. Biological fluid assay system and method
JPS60100035A (ja) * 1983-11-04 1985-06-03 Kyoto Daiichi Kagaku:Kk 散乱光を用いる測定方法及び測定装置
DE3501093C1 (de) * 1985-01-15 1986-06-12 Drägerwerk AG, 2400 Lübeck Gasmess- und Warnvorrichtung
US4567754A (en) * 1985-03-29 1986-02-04 Wardlaw Stephen C Measurement of small heavy constituent layer in stratified mixture
JPS6235244A (ja) * 1985-08-09 1987-02-16 Sato Yakugaku Kenkyusho:Kk 新しい高速液体クロマトグラフイ−
US4732479A (en) * 1985-10-18 1988-03-22 Canon Kabushiki Kaisha Particle analyzing apparatus
US4683579A (en) * 1985-12-27 1987-07-28 Wardlaw Stephen C Method and apparatus for measuring blood constituent counts
US4843869A (en) * 1988-03-21 1989-07-04 Levine Robert A Method for measuring hemoglobin
US4953975A (en) * 1989-01-30 1990-09-04 Levine Robert A Correction of material layer volume measurements
DE4016291C1 (en) * 1990-05-21 1991-11-21 Gerhard Dr.Med.Vet. 5100 Aachen De Staudacher Device for measuring coated structures of sample e.g. blood - has magnifying glass around centrifugal tube carrier and A=D converter forming digital signals for computer
US5321975A (en) * 1991-10-04 1994-06-21 Levine Robert A Differential erythrocyte counts
US5506145A (en) * 1994-12-02 1996-04-09 Bull; Brian S. Determination of an individual's inflammation index from whole blood fibrinogen and hematocrit or hemoglobin measurements
GB9606559D0 (en) * 1996-03-28 1996-06-05 Zynocyte Ltd Apparatus and method for analysing blood samples
US5705739A (en) * 1996-08-27 1998-01-06 Levine; Robert A. Detecting specific medical conditions from erythrocyte density distrubition in a centrifuged anticoagulated whole blood sample
US6152868A (en) * 1998-03-02 2000-11-28 Becton, Dickinson And Company Inertial tube indexer
US5889584A (en) * 1997-03-10 1999-03-30 Robert A. Levine Assembly for rapid measurement of cell layers
US5888184A (en) * 1997-03-10 1999-03-30 Robert A. Levine Method for rapid measurement of cell layers
US5811303A (en) * 1997-04-01 1998-09-22 Streck Laboratories, Inc. Quantitative buffy coat control composition
DE69819996T2 (de) * 1997-09-27 2004-09-02 Horiba Ltd. Gerät für die Zählung von Blutzellen und zur immunologischen Bestimmung unter Verwendung von Vollblut
US6030086A (en) * 1998-03-02 2000-02-29 Becton, Dickinson And Company Flash tube reflector with arc guide
US6002474A (en) * 1998-03-02 1999-12-14 Becton Dickinson And Company Method for using blood centrifugation device with movable optical reader
US6080366A (en) * 1998-03-02 2000-06-27 Becton, Dickinson And Company Disposable blood tube holder
US6120429A (en) * 1998-03-02 2000-09-19 Becton, Dickinson And Company Method of using inertial tube indexer
US6074883A (en) * 1998-03-02 2000-06-13 Becton, Dickinson And Company Method for using disposable blood tube holder
US6285450B1 (en) 1998-03-02 2001-09-04 Bradley S. Thomas Blood centrifugation device with movable optical reader
US6350613B1 (en) * 1998-03-07 2002-02-26 Belton Dickinson & Co. Determination of white blood cell differential and reticulocyte counts
WO1999046047A2 (en) 1998-03-10 1999-09-16 Large Scale Proteomics Corporation Detection and characterization of microorganisms
US6153148A (en) * 1998-06-15 2000-11-28 Becton, Dickinson And Company Centrifugal hematology disposable
US6388740B1 (en) * 1999-06-22 2002-05-14 Robert A. Levine Method and apparatus for timing intermittent illumination of a sample tube positioned on a centrifuge platen and for calibrating a sample tube imaging system
US6204066B1 (en) * 1999-06-25 2001-03-20 Robert A. Levine Rapid method for determining the erythrocyte sedimentation rate in a sample of anticoagulated whole blood
CH694062A5 (de) * 1999-07-26 2004-06-30 Tecan Trading Ag Prüfeinrichtung und Verfahren zu ihrem Betrieb.
RU2196328C1 (ru) * 2001-05-04 2003-01-10 Корякин Софрон Павлович Применение планшетного иммуноферментного анализатора в качестве гемоглобинометра
GB0419059D0 (en) * 2004-08-26 2004-09-29 Ici Plc Sediment assessment
US7998696B2 (en) * 2007-12-05 2011-08-16 Zyomyx, Inc. Cell assay kit and method
EP2249701B1 (en) 2008-03-05 2020-04-29 Becton, Dickinson and Company Capillary action collection container assembly
US8446586B2 (en) * 2008-10-15 2013-05-21 Allan Yang Wu Method and apparatus for increasing adipose vascular fraction
US20110178424A1 (en) * 2010-01-19 2011-07-21 Becton, Dickinson And Company Specimen Collection Container Having a Transitional Fill-Volume Indicator Indicating Extraction Method
US20110201045A1 (en) 2010-02-17 2011-08-18 Levine Joshua D Method and apparatus for performing hematologic analysis using an array-imaging system for imaging and analysis of a centrifuged analysis tube
US8460620B2 (en) 2010-12-03 2013-06-11 Becton, Dickinson And Company Specimen collection container assembly
US8984932B2 (en) 2012-07-18 2015-03-24 Theranos, Inc. Rapid measurement of formed blood component sedimentation rate from small sample volumes
CN110187089B (zh) 2012-07-18 2021-10-29 赛拉诺斯知识产权有限责任公司 快速测量小容量样本中有形血液成分的沉降率
CN103528936B (zh) * 2013-10-23 2016-05-18 北京倍肯恒业科技发展股份有限公司 一种干式血液细胞分析装置的光学检测系统
CN103529230B (zh) * 2013-10-23 2015-07-29 北京倍肯恒业科技发展有限责任公司 一种干式血液细胞分析装置
CN103558403A (zh) * 2013-10-23 2014-02-05 北京倍肯恒业科技发展有限责任公司 一种干式血液细胞分析装置的主控数据处理系统
CN103529231B (zh) * 2013-10-23 2016-01-13 北京倍肯恒业科技发展有限责任公司 一种干式血液细胞分析装置的机械进样系统
CN103776768A (zh) * 2013-10-25 2014-05-07 北京倍肯恒业科技发展有限责任公司 一种干式血液细胞分析方法
RU2645081C1 (ru) * 2016-12-28 2018-02-15 Анна Николаевна Плаксина Анализатор коагуляции - тромбоэластограф
IL267950B2 (en) * 2017-01-11 2025-04-01 Cypher Medical Llc Blood volume estimation method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679367A (en) * 1970-09-14 1972-07-25 Technicon Instr Apparatus for determining the pack volume of particulates in liquid mixtures
US4156570A (en) * 1977-04-18 1979-05-29 Robert A. Levine Apparatus and method for measuring white blood cell and platelet concentrations in blood
FR2413661A1 (fr) * 1977-12-30 1979-07-27 Nancy 1 Universite Dispositif de mesure de la vitesse de sedimentation d'echantillons de sang
US4350441A (en) * 1980-06-30 1982-09-21 Baxter Travenol Laboratories, Inc. Photometric apparatus and method

Also Published As

Publication number Publication date
US4558947A (en) 1985-12-17
JPS60123764A (ja) 1985-07-02
EP0142120A3 (en) 1986-04-02
DE3481444D1 (de) 1990-04-05
EP0142120B1 (en) 1990-02-28
ATE50641T1 (de) 1990-03-15
BR8405557A (pt) 1985-09-10
JPH0369070B2 (enExample) 1991-10-30
EP0142120A2 (en) 1985-05-22

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