DE122005000043I1 - Zusammensetzungen zur Erzielung von analgesie und zur Hemmung der Progression neuropatisher Schmerz erkrankungen - Google Patents
Zusammensetzungen zur Erzielung von analgesie und zur Hemmung der Progression neuropatisher Schmerz erkrankungenInfo
- Publication number
- DE122005000043I1 DE122005000043I1 DE1996627153 DE69627153C DE122005000043I1 DE 122005000043 I1 DE122005000043 I1 DE 122005000043I1 DE 1996627153 DE1996627153 DE 1996627153 DE 69627153 C DE69627153 C DE 69627153C DE 122005000043 I1 DE122005000043 I1 DE 122005000043I1
- Authority
- DE
- Germany
- Prior art keywords
- progression
- inhibiting
- neuropathic pain
- compositions
- pain disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Control Of El Displays (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/496,847 US5795864A (en) | 1995-06-27 | 1995-06-27 | Stable omega conopetide formulations |
US08/613,400 US6054429A (en) | 1996-03-08 | 1996-03-08 | Epidural method of producing analgesia |
PCT/US1996/011041 WO1997001351A1 (en) | 1995-06-27 | 1996-06-26 | Compositions and formulations for producing analgesia and for inhibiting progression of neuropathic pain disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
DE122005000043I1 true DE122005000043I1 (de) | 2006-06-29 |
DE122005000043I2 DE122005000043I2 (de) | 2006-08-03 |
Family
ID=27052304
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69627153T Expired - Lifetime DE69627153T2 (de) | 1995-06-27 | 1996-06-26 | Zusammensetzungen zur erzielung von analgesie und zur hemmung der progression neuropathischer schmerzerkrankungen |
DE1996627153 Active DE122005000043I2 (de) | 1995-06-27 | 1996-06-26 | Zusammensetzungen zur Erzielung von Analgesie und zur Hemmung der progression neuropathischer Schmerzerkrankungen |
DE69637021T Expired - Lifetime DE69637021T2 (de) | 1995-06-27 | 1996-06-26 | Zusammensetzungen zur Erzielung von Analgesie und zur Hemmung der Progression neuropathischer Schmerzerkrankungen |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69627153T Expired - Lifetime DE69627153T2 (de) | 1995-06-27 | 1996-06-26 | Zusammensetzungen zur erzielung von analgesie und zur hemmung der progression neuropathischer schmerzerkrankungen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69637021T Expired - Lifetime DE69637021T2 (de) | 1995-06-27 | 1996-06-26 | Zusammensetzungen zur Erzielung von Analgesie und zur Hemmung der Progression neuropathischer Schmerzerkrankungen |
Country Status (14)
Country | Link |
---|---|
EP (2) | EP1336409B1 (de) |
JP (1) | JP2838073B2 (de) |
AT (2) | ATE235914T1 (de) |
AU (1) | AU695166B2 (de) |
CA (1) | CA2224795C (de) |
DE (3) | DE69627153T2 (de) |
DK (2) | DK0835126T3 (de) |
ES (2) | ES2194998T3 (de) |
FR (1) | FR05C0027I2 (de) |
HK (1) | HK1058146A1 (de) |
LU (1) | LU91181I2 (de) |
NL (1) | NL300201I2 (de) |
PT (2) | PT835126E (de) |
WO (1) | WO1997001351A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5931809A (en) | 1995-07-14 | 1999-08-03 | Depotech Corporation | Epidural administration of therapeutic compounds with sustained rate of release |
AU6109698A (en) * | 1998-02-20 | 1999-09-06 | Zeneca Limited | Analgesic peptides from venom of (grammostola spatulata) and use thereof |
AUPP627498A0 (en) | 1998-10-02 | 1998-10-22 | University Of Queensland, The | Novel peptides - i |
WO2004050688A1 (en) | 2002-12-02 | 2004-06-17 | Xenome Ltd | NOVEL χ-CONOTOXIN PEPTIDES (-II) |
EP1572725B1 (de) | 2002-12-02 | 2012-02-29 | Xenome Ltd | Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
DE602004007105T2 (de) | 2003-01-28 | 2008-02-28 | Microbia Inc., Cambridge | Zusammensetzung zur behandlung von gastrointestinalen störungen |
CA2540895C (en) | 2003-10-02 | 2016-08-02 | Elan Pharmaceuticals, Inc. | Combinations of ziconotide and opioids for reducing pain |
GB0410215D0 (en) * | 2004-05-07 | 2004-06-09 | Lescroart Pol | Nerve damage |
US8188048B2 (en) | 2006-06-23 | 2012-05-29 | Xenome Limited | Combination therapy |
WO2008054171A1 (en) * | 2006-11-04 | 2008-05-08 | Anygen Co., Ltd. | Omega conotoxins |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
AU2008261102B2 (en) | 2007-06-04 | 2013-11-28 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
WO2009135258A1 (en) * | 2008-05-06 | 2009-11-12 | Cnsbio Pty Ltd | Methods and compositions for the management of pain using omega-conotoxins |
EP2328910B1 (de) | 2008-06-04 | 2014-08-06 | Synergy Pharmaceuticals Inc. | Für die behandlung von gastrointestinalen erkrankungen, entzündungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase |
EP3241839B1 (de) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Zur behandlung von erkrankungen des magen-darm-trakts, entzündlichen erkrankungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase |
CA2745694C (en) | 2008-12-03 | 2018-03-27 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase c agonists and methods of use |
KR20200111230A (ko) | 2008-12-31 | 2020-09-28 | 알데릭스, 인코포레이티드 | 체액 저류 또는 염 과부하와 연관된 장애 및 위장관 장애의 치료 시에 nhe-매개된 역수송을 억제하는 화합물 및 방법 |
WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
US10376481B2 (en) | 2012-08-21 | 2019-08-13 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
EP2887964B1 (de) | 2012-08-21 | 2019-07-03 | Ardelyx, Inc. | Verbindungen und verfahren zur hemmung von nhe-vermitteltem antiport bei der behandlung von erkrankungen im zusammenhang mit flüssigkeitsretention oder salzüberlastung und erkrankungen des gastrointestinaltraktes |
WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
PL2983667T3 (pl) | 2013-04-12 | 2019-10-31 | Ardelyx Inc | Związki wiążące nhe3 oraz sposoby inhibicji transportu fosforanów |
BR112015030326A2 (pt) | 2013-06-05 | 2017-08-29 | Synergy Pharmaceuticals Inc | Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos |
AU2018205400B2 (en) | 2017-01-09 | 2022-07-14 | Ardelyx, Inc. | Compounds useful for treating gastrointestinal tract disorders |
JP2020505333A (ja) | 2017-01-09 | 2020-02-20 | アルデリックス, インコーポレイテッド | Nhe媒介性アンチポートの阻害薬 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3926287A1 (de) * | 1989-08-09 | 1991-02-21 | Bernhard Clasbrummel | Medizinische anwendung von omega-conotoxin gvia oder omega-conotoxin gvia-analoga zur sympathikolyse |
US5051403A (en) * | 1989-11-22 | 1991-09-24 | Neurex Corporation | Method of treating ischemia-related neuronal damage |
WO1993010145A1 (en) * | 1991-11-12 | 1993-05-27 | Neurex Corporation | Compositions for delayed treatment of ischemia-related neuronal damage |
AU689438B2 (en) * | 1991-12-30 | 1998-04-02 | Azur Pharma International Limited | Methods of producing analgesia and enhancing opiate analgesia |
JPH06247879A (ja) * | 1993-02-17 | 1994-09-06 | Bristol Myers Squibb Co | デオキシチミジンヌクレオシドを含有する注射用製剤の安定化方法およびその方法によって得られる安定化注射用製剤 |
-
1996
- 1996-06-26 DK DK96923511T patent/DK0835126T3/da active
- 1996-06-26 AU AU64002/96A patent/AU695166B2/en not_active Ceased
- 1996-06-26 PT PT96923511T patent/PT835126E/pt unknown
- 1996-06-26 ES ES96923511T patent/ES2194998T3/es not_active Expired - Lifetime
- 1996-06-26 AT AT96923511T patent/ATE235914T1/de active
- 1996-06-26 DE DE69627153T patent/DE69627153T2/de not_active Expired - Lifetime
- 1996-06-26 DE DE1996627153 patent/DE122005000043I2/de active Active
- 1996-06-26 PT PT03007342T patent/PT1336409E/pt unknown
- 1996-06-26 ES ES03007342T patent/ES2283671T3/es not_active Expired - Lifetime
- 1996-06-26 AT AT03007342T patent/ATE359086T1/de active
- 1996-06-26 EP EP03007342A patent/EP1336409B1/de not_active Expired - Lifetime
- 1996-06-26 CA CA002224795A patent/CA2224795C/en not_active Expired - Fee Related
- 1996-06-26 WO PCT/US1996/011041 patent/WO1997001351A1/en active IP Right Grant
- 1996-06-26 DK DK03007342T patent/DK1336409T3/da active
- 1996-06-26 EP EP96923511A patent/EP0835126B1/de not_active Expired - Lifetime
- 1996-06-26 DE DE69637021T patent/DE69637021T2/de not_active Expired - Lifetime
- 1996-06-27 JP JP8188120A patent/JP2838073B2/ja not_active Expired - Fee Related
-
2004
- 2004-02-10 HK HK04100882A patent/HK1058146A1/xx not_active IP Right Cessation
-
2005
- 2005-06-23 FR FR05C0027C patent/FR05C0027I2/fr active Active
- 2005-07-06 LU LU91181C patent/LU91181I2/fr unknown
- 2005-07-13 NL NL300201C patent/NL300201I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
EP0835126A1 (de) | 1998-04-15 |
DE69637021D1 (de) | 2007-05-24 |
DE69637021T2 (de) | 2008-01-10 |
JPH09104634A (ja) | 1997-04-22 |
NL300201I2 (nl) | 2006-02-01 |
AU695166B2 (en) | 1998-08-06 |
AU6400296A (en) | 1997-01-30 |
WO1997001351A1 (en) | 1997-01-16 |
ES2194998T3 (es) | 2003-12-01 |
DE69627153T2 (de) | 2003-12-04 |
PT1336409E (pt) | 2007-06-29 |
NL300201I1 (nl) | 2005-09-01 |
PT835126E (pt) | 2003-07-31 |
FR05C0027I1 (de) | 2005-08-12 |
JP2838073B2 (ja) | 1998-12-16 |
LU91181I2 (fr) | 2005-09-06 |
EP1336409A1 (de) | 2003-08-20 |
DK0835126T3 (da) | 2003-07-14 |
ATE235914T1 (de) | 2003-04-15 |
CA2224795A1 (en) | 1997-01-16 |
DK1336409T3 (da) | 2007-08-13 |
HK1058146A1 (en) | 2004-05-07 |
ES2283671T3 (es) | 2007-11-01 |
EP0835126B1 (de) | 2003-04-02 |
ATE359086T1 (de) | 2007-05-15 |
EP1336409B1 (de) | 2007-04-11 |
FR05C0027I2 (de) | 2006-12-29 |
CA2224795C (en) | 2001-04-03 |
DE69627153D1 (de) | 2003-05-08 |
DE122005000043I2 (de) | 2006-08-03 |
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