DE122005000043I1 - Zusammensetzungen zur Erzielung von analgesie und zur Hemmung der Progression neuropatisher Schmerz erkrankungen - Google Patents

Zusammensetzungen zur Erzielung von analgesie und zur Hemmung der Progression neuropatisher Schmerz erkrankungen

Info

Publication number
DE122005000043I1
DE122005000043I1 DE1996627153 DE69627153C DE122005000043I1 DE 122005000043 I1 DE122005000043 I1 DE 122005000043I1 DE 1996627153 DE1996627153 DE 1996627153 DE 69627153 C DE69627153 C DE 69627153C DE 122005000043 I1 DE122005000043 I1 DE 122005000043I1
Authority
DE
Germany
Prior art keywords
progression
inhibiting
neuropathic pain
compositions
pain disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE1996627153
Other languages
English (en)
Other versions
DE69627153T2 (de
DE69627153D1 (de
DE122005000043I2 (de
Inventor
R Luther
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Pharmaceuticals LLC
Original Assignee
Elan Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/496,847 external-priority patent/US5795864A/en
Priority claimed from US08/613,400 external-priority patent/US6054429A/en
Application filed by Elan Pharmaceuticals LLC filed Critical Elan Pharmaceuticals LLC
Publication of DE122005000043I1 publication Critical patent/DE122005000043I1/de
Publication of DE122005000043I2 publication Critical patent/DE122005000043I2/de
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Control Of El Displays (AREA)
  • Saccharide Compounds (AREA)
DE1996627153 1995-06-27 1996-06-26 Zusammensetzungen zur Erzielung von Analgesie und zur Hemmung der progression neuropathischer Schmerzerkrankungen Active DE122005000043I2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/496,847 US5795864A (en) 1995-06-27 1995-06-27 Stable omega conopetide formulations
US08/613,400 US6054429A (en) 1996-03-08 1996-03-08 Epidural method of producing analgesia
PCT/US1996/011041 WO1997001351A1 (en) 1995-06-27 1996-06-26 Compositions and formulations for producing analgesia and for inhibiting progression of neuropathic pain disorders

Publications (2)

Publication Number Publication Date
DE122005000043I1 true DE122005000043I1 (de) 2006-06-29
DE122005000043I2 DE122005000043I2 (de) 2006-08-03

Family

ID=27052304

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69627153T Expired - Lifetime DE69627153T2 (de) 1995-06-27 1996-06-26 Zusammensetzungen zur erzielung von analgesie und zur hemmung der progression neuropathischer schmerzerkrankungen
DE1996627153 Active DE122005000043I2 (de) 1995-06-27 1996-06-26 Zusammensetzungen zur Erzielung von Analgesie und zur Hemmung der progression neuropathischer Schmerzerkrankungen
DE69637021T Expired - Lifetime DE69637021T2 (de) 1995-06-27 1996-06-26 Zusammensetzungen zur Erzielung von Analgesie und zur Hemmung der Progression neuropathischer Schmerzerkrankungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69627153T Expired - Lifetime DE69627153T2 (de) 1995-06-27 1996-06-26 Zusammensetzungen zur erzielung von analgesie und zur hemmung der progression neuropathischer schmerzerkrankungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69637021T Expired - Lifetime DE69637021T2 (de) 1995-06-27 1996-06-26 Zusammensetzungen zur Erzielung von Analgesie und zur Hemmung der Progression neuropathischer Schmerzerkrankungen

Country Status (14)

Country Link
EP (2) EP1336409B1 (de)
JP (1) JP2838073B2 (de)
AT (2) ATE235914T1 (de)
AU (1) AU695166B2 (de)
CA (1) CA2224795C (de)
DE (3) DE69627153T2 (de)
DK (2) DK0835126T3 (de)
ES (2) ES2194998T3 (de)
FR (1) FR05C0027I2 (de)
HK (1) HK1058146A1 (de)
LU (1) LU91181I2 (de)
NL (1) NL300201I2 (de)
PT (2) PT835126E (de)
WO (1) WO1997001351A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5931809A (en) 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
AU6109698A (en) * 1998-02-20 1999-09-06 Zeneca Limited Analgesic peptides from venom of (grammostola spatulata) and use thereof
AUPP627498A0 (en) 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
WO2004050688A1 (en) 2002-12-02 2004-06-17 Xenome Ltd NOVEL χ-CONOTOXIN PEPTIDES (-II)
EP1572725B1 (de) 2002-12-02 2012-02-29 Xenome Ltd Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
DE602004007105T2 (de) 2003-01-28 2008-02-28 Microbia Inc., Cambridge Zusammensetzung zur behandlung von gastrointestinalen störungen
CA2540895C (en) 2003-10-02 2016-08-02 Elan Pharmaceuticals, Inc. Combinations of ziconotide and opioids for reducing pain
GB0410215D0 (en) * 2004-05-07 2004-06-09 Lescroart Pol Nerve damage
US8188048B2 (en) 2006-06-23 2012-05-29 Xenome Limited Combination therapy
WO2008054171A1 (en) * 2006-11-04 2008-05-08 Anygen Co., Ltd. Omega conotoxins
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
AU2008261102B2 (en) 2007-06-04 2013-11-28 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2009135258A1 (en) * 2008-05-06 2009-11-12 Cnsbio Pty Ltd Methods and compositions for the management of pain using omega-conotoxins
EP2328910B1 (de) 2008-06-04 2014-08-06 Synergy Pharmaceuticals Inc. Für die behandlung von gastrointestinalen erkrankungen, entzündungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase
EP3241839B1 (de) 2008-07-16 2019-09-04 Bausch Health Ireland Limited Zur behandlung von erkrankungen des magen-darm-trakts, entzündlichen erkrankungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase
CA2745694C (en) 2008-12-03 2018-03-27 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase c agonists and methods of use
KR20200111230A (ko) 2008-12-31 2020-09-28 알데릭스, 인코포레이티드 체액 저류 또는 염 과부하와 연관된 장애 및 위장관 장애의 치료 시에 ｎｈｅ-매개된 역수송을 억제하는 화합물 및 방법
WO2018129556A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US10376481B2 (en) 2012-08-21 2019-08-13 Ardelyx, Inc. Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
EP2887964B1 (de) 2012-08-21 2019-07-03 Ardelyx, Inc. Verbindungen und verfahren zur hemmung von nhe-vermitteltem antiport bei der behandlung von erkrankungen im zusammenhang mit flüssigkeitsretention oder salzüberlastung und erkrankungen des gastrointestinaltraktes
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
PL2983667T3 (pl) 2013-04-12 2019-10-31 Ardelyx Inc Związki wiążące nhe3 oraz sposoby inhibicji transportu fosforanów
BR112015030326A2 (pt) 2013-06-05 2017-08-29 Synergy Pharmaceuticals Inc Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos
AU2018205400B2 (en) 2017-01-09 2022-07-14 Ardelyx, Inc. Compounds useful for treating gastrointestinal tract disorders
JP2020505333A (ja) 2017-01-09 2020-02-20 アルデリックス， インコーポレイテッド Ｎｈｅ媒介性アンチポートの阻害薬

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3926287A1 (de) * 1989-08-09 1991-02-21 Bernhard Clasbrummel Medizinische anwendung von omega-conotoxin gvia oder omega-conotoxin gvia-analoga zur sympathikolyse
US5051403A (en) * 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
WO1993010145A1 (en) * 1991-11-12 1993-05-27 Neurex Corporation Compositions for delayed treatment of ischemia-related neuronal damage
AU689438B2 (en) * 1991-12-30 1998-04-02 Azur Pharma International Limited Methods of producing analgesia and enhancing opiate analgesia
JPH06247879A (ja) * 1993-02-17 1994-09-06 Bristol Myers Squibb Co デオキシチミジンヌクレオシドを含有する注射用製剤の安定化方法およびその方法によって得られる安定化注射用製剤

Also Published As

Publication number Publication date
EP0835126A1 (de) 1998-04-15
DE69637021D1 (de) 2007-05-24
DE69637021T2 (de) 2008-01-10
JPH09104634A (ja) 1997-04-22
NL300201I2 (nl) 2006-02-01
AU695166B2 (en) 1998-08-06
AU6400296A (en) 1997-01-30
WO1997001351A1 (en) 1997-01-16
ES2194998T3 (es) 2003-12-01
DE69627153T2 (de) 2003-12-04
PT1336409E (pt) 2007-06-29
NL300201I1 (nl) 2005-09-01
PT835126E (pt) 2003-07-31
FR05C0027I1 (de) 2005-08-12
JP2838073B2 (ja) 1998-12-16
LU91181I2 (fr) 2005-09-06
EP1336409A1 (de) 2003-08-20
DK0835126T3 (da) 2003-07-14
ATE235914T1 (de) 2003-04-15
CA2224795A1 (en) 1997-01-16
DK1336409T3 (da) 2007-08-13
HK1058146A1 (en) 2004-05-07
ES2283671T3 (es) 2007-11-01
EP0835126B1 (de) 2003-04-02
ATE359086T1 (de) 2007-05-15
EP1336409B1 (de) 2007-04-11
FR05C0027I2 (de) 2006-12-29
CA2224795C (en) 2001-04-03
DE69627153D1 (de) 2003-05-08
DE122005000043I2 (de) 2006-08-03

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