DE112017002105T5 - Verfahren zur Bestimmung von DPP3 und therapeutische Verfahren - Google Patents

Verfahren zur Bestimmung von DPP3 und therapeutische Verfahren Download PDF

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Publication number
DE112017002105T5
DE112017002105T5 DE112017002105.7T DE112017002105T DE112017002105T5 DE 112017002105 T5 DE112017002105 T5 DE 112017002105T5 DE 112017002105 T DE112017002105 T DE 112017002105T DE 112017002105 T5 DE112017002105 T5 DE 112017002105T5
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Prior art keywords
dpp3
subject
disease
antibody
condition
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DE112017002105.7T
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German (de)
English (en)
Inventor
Andreas Bergmann
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4Teen4 Pharmaceuticals GmbH
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Sphingotec Therapeutics GmbH
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    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
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    • C07K—PEPTIDES
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    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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  • General Chemical & Material Sciences (AREA)
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  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
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DE112017002105.7T 2016-04-21 2017-04-20 Verfahren zur Bestimmung von DPP3 und therapeutische Verfahren Pending DE112017002105T5 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16166476 2016-04-21
EP16166476.8 2016-04-21
PCT/EP2017/059377 WO2017182561A1 (en) 2016-04-21 2017-04-20 Methods for determining dpp3 and therapeutic methods

Publications (1)

Publication Number Publication Date
DE112017002105T5 true DE112017002105T5 (de) 2019-04-25

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ID=56014788

Family Applications (1)

Application Number Title Priority Date Filing Date
DE112017002105.7T Pending DE112017002105T5 (de) 2016-04-21 2017-04-20 Verfahren zur Bestimmung von DPP3 und therapeutische Verfahren

Country Status (15)

Country Link
US (3) US20190145981A1 (https=)
EP (5) EP3446125B1 (https=)
JP (4) JP2019520550A (https=)
KR (3) KR102565453B1 (https=)
CN (3) CN120093910A (https=)
AU (1) AU2017252212B2 (https=)
BR (1) BR112018071583A2 (https=)
CA (2) CA3264486A1 (https=)
CH (1) CH713803B1 (https=)
DE (1) DE112017002105T5 (https=)
IL (1) IL262472B2 (https=)
MX (3) MX2018012856A (https=)
MY (1) MY200300A (https=)
SG (1) SG11201809252YA (https=)
WO (1) WO2017182561A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017252212B2 (en) * 2016-04-21 2023-09-07 4TEEN4 Pharmaceuticals GmbH Methods for determining DPP3 and therapeutic methods
MY202502A (en) * 2017-10-25 2024-05-01 4TEEN4 Pharmaceuticals GmbH Dpp3 binder directed to and binding to specific dpp3-epitopes and its use in the prevention or treatment of diseases / acute conditions that are associated with oxidative stress
WO2020128039A2 (en) * 2018-12-21 2020-06-25 4TEEN4 Pharmaceuticals GmbH Therapy guidance and/or therapy monitoring for a treatment with angiotensin-receptor-agonist and/or a precursor thereof
BR112022002856A2 (pt) * 2019-08-30 2022-08-09 4TEEN4 Pharmaceuticals GmbH Orientação de terapia e/ou monitoramento de terapia para o tratamento de choque
MX2022010564A (es) 2020-02-27 2022-11-30 Adrenomed Ag Aglutinante anti-adrenomedulina (adm) para usarse en terapia de pacientes en choque.
CA3168978A1 (en) * 2020-02-27 2021-09-02 Andreas Bergmann Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy or prevention of shock
CN115244401A (zh) * 2020-02-27 2022-10-25 4Teen4制药有限公司 用于在休克患者中进行nt-adm抗体的治疗指导、监测和分层的dpp3
EP3922993A1 (en) 2020-06-12 2021-12-15 4TEEN4 Pharmaceuticals GmbH Dpp3 in patients infected with coronavirus
WO2021185786A1 (en) 2020-03-16 2021-09-23 4TEEN4 Pharmaceuticals GmbH Dpp3 in patients infected with coronavirus
CA3254142A1 (en) 2022-03-15 2023-09-21 Adrenomed Ag STABLE AQUEOUS FORMULATION OF AN ANTI-ADRENOMEDULLIN (ADM) ANTIBODY OR AN ANTI-ADM ANTIBODY FRAGMENT
CN117186177B (zh) * 2022-05-31 2024-08-23 中国农业大学 一种具有降尿酸活性的鸭血球蛋白肽及其制备方法
KR20250042158A (ko) 2022-07-29 2025-03-26 아드레노메드 아게 쇼크의 요법 또는 예방에 사용하기 위한 항-아드레노메둘린 (ADM) 항체 또는 항-ADM 항체 단편 또는 항-ADM 비-Ig 스캐폴드
CN119630969A (zh) 2022-07-29 2025-03-14 4Teen4制药有限公司 预测患有败血症性休克的患者中的dpp3增加
CN120359042A (zh) 2022-12-15 2025-07-22 4Teen4制药有限公司 改善危重病患者肺功能的dpp3抑制剂
CN115804836A (zh) * 2022-12-27 2023-03-17 中国人民解放军海军特色医学中心 一种中枢小分子蛋白dpp3在制备降压药物中的应用
WO2024200862A1 (en) 2023-03-29 2024-10-03 4TEEN4 Pharmaceuticals GmbH Dpp3 inhibitor for myocardial protection and prevention of myocardial injury in critically ill patients with blood pressure decline
WO2026046947A1 (en) 2024-08-26 2026-03-05 4TEEN4 Pharmaceuticals GmbH Anti-dpp3 antibody directed to and binding to dpp3 for the treatment of shock in extreme-critically ill patients
WO2026046968A1 (en) 2024-08-26 2026-03-05 4TEEN4 Pharmaceuticals GmbH Dpp3 binders for the treatment of endothelial dysfunction

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WO1993012227A1 (en) 1991-12-17 1993-06-24 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
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