DE10261241A1 - Dentalmaterial mit bakteriostatischen und/oder bakteriziden Substanzen - Google Patents
Dentalmaterial mit bakteriostatischen und/oder bakteriziden Substanzen Download PDFInfo
- Publication number
- DE10261241A1 DE10261241A1 DE10261241A DE10261241A DE10261241A1 DE 10261241 A1 DE10261241 A1 DE 10261241A1 DE 10261241 A DE10261241 A DE 10261241A DE 10261241 A DE10261241 A DE 10261241A DE 10261241 A1 DE10261241 A1 DE 10261241A1
- Authority
- DE
- Germany
- Prior art keywords
- dental material
- substance
- dental
- material according
- taurolidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000005548 dental material Substances 0.000 title claims abstract description 64
- 239000000126 substance Substances 0.000 title claims abstract description 63
- 230000003385 bacteriostatic effect Effects 0.000 title claims abstract description 21
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 20
- 244000005700 microbiome Species 0.000 claims abstract description 29
- AJKIRUJIDFJUKJ-UHFFFAOYSA-N taurolidine Chemical compound C1NS(=O)(=O)CCN1CN1CNS(=O)(=O)CC1 AJKIRUJIDFJUKJ-UHFFFAOYSA-N 0.000 claims description 60
- 229960004267 taurolidine Drugs 0.000 claims description 60
- 239000000463 material Substances 0.000 claims description 24
- 239000004480 active ingredient Substances 0.000 claims description 16
- 230000002255 enzymatic effect Effects 0.000 claims description 12
- 239000003178 glass ionomer cement Substances 0.000 claims description 11
- 230000001960 triggered effect Effects 0.000 claims description 10
- 210000003298 dental enamel Anatomy 0.000 claims description 8
- 210000004268 dentin Anatomy 0.000 claims description 8
- 230000004048 modification Effects 0.000 claims description 7
- 238000012986 modification Methods 0.000 claims description 7
- 238000009792 diffusion process Methods 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 238000001212 derivatisation Methods 0.000 claims description 5
- 230000015572 biosynthetic process Effects 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 239000000945 filler Substances 0.000 claims 3
- 239000003999 initiator Substances 0.000 claims 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- 238000003776 cleavage reaction Methods 0.000 claims 1
- 239000002978 dental impression material Substances 0.000 claims 1
- 230000007613 environmental effect Effects 0.000 claims 1
- 230000007017 scission Effects 0.000 claims 1
- 241000894006 Bacteria Species 0.000 description 18
- 230000000694 effects Effects 0.000 description 12
- 241000186660 Lactobacillus Species 0.000 description 9
- 241000183024 Populus tremula Species 0.000 description 9
- 230000001580 bacterial effect Effects 0.000 description 9
- 239000003795 chemical substances by application Substances 0.000 description 9
- 230000034994 death Effects 0.000 description 9
- 229940039696 lactobacillus Drugs 0.000 description 9
- 239000003068 molecular probe Substances 0.000 description 9
- 239000000243 solution Substances 0.000 description 9
- 230000035899 viability Effects 0.000 description 9
- 229920001296 polysiloxane Polymers 0.000 description 7
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 6
- 229940072056 alginate Drugs 0.000 description 6
- 235000010443 alginic acid Nutrition 0.000 description 6
- 229920000615 alginic acid Polymers 0.000 description 6
- 230000000704 physical effect Effects 0.000 description 6
- 239000000654 additive Substances 0.000 description 4
- 230000000845 anti-microbial effect Effects 0.000 description 4
- 239000002521 compomer Substances 0.000 description 4
- 239000002131 composite material Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 239000004721 Polyphenylene oxide Substances 0.000 description 3
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 3
- 230000000996 additive effect Effects 0.000 description 3
- 229920000570 polyether Polymers 0.000 description 3
- RJGYJMFQWGPBGM-UHFFFAOYSA-N 1,2,4-thiadiazinane 1,1-dioxide Chemical compound O=S1(=O)CCNCN1 RJGYJMFQWGPBGM-UHFFFAOYSA-N 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000002207 metabolite Substances 0.000 description 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 229950007343 taurultam Drugs 0.000 description 2
- 229960003500 triclosan Drugs 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- QJDQHBZBKSPGOW-UHFFFAOYSA-N 2-amino-n-diazoethanesulfonamide Chemical compound NCCS(=O)(=O)N=[N+]=[N-] QJDQHBZBKSPGOW-UHFFFAOYSA-N 0.000 description 1
- MVQXBXLDXSQURK-UHFFFAOYSA-N 2-aminoethanesulfonamide Chemical compound NCCS(N)(=O)=O MVQXBXLDXSQURK-UHFFFAOYSA-N 0.000 description 1
- ODVGAMNNBWDLGH-UHFFFAOYSA-N 2-azido-n-diazoethanesulfonamide Chemical compound [N-]=[N+]=NCCS(=O)(=O)N=[N+]=[N-] ODVGAMNNBWDLGH-UHFFFAOYSA-N 0.000 description 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
- 208000010266 Aggressive Periodontitis Diseases 0.000 description 1
- 235000006679 Mentha X verticillata Nutrition 0.000 description 1
- 235000002899 Mentha suaveolens Nutrition 0.000 description 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 description 1
- 206010039424 Salivary hypersecretion Diseases 0.000 description 1
- 235000011054 acetic acid Nutrition 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 239000001926 citrus aurantium l. subsp. bergamia wright et arn. oil Substances 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 239000003479 dental cement Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000010642 eucalyptus oil Substances 0.000 description 1
- 229940044949 eucalyptus oil Drugs 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000020477 pH reduction Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 201000006727 periodontosis Diseases 0.000 description 1
- 210000001322 periplasm Anatomy 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 239000012487 rinsing solution Substances 0.000 description 1
- 208000026451 salivation Diseases 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
- A61K6/69—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/30—Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
- A61K6/887—Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
- A61K6/887—Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
- A61K6/889—Polycarboxylate cements; Glass ionomer cements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/90—Compositions for taking dental impressions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Plastic & Reconstructive Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dental Preparations (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10261241A DE10261241A1 (de) | 2002-12-20 | 2002-12-20 | Dentalmaterial mit bakteriostatischen und/oder bakteriziden Substanzen |
| EP03789178A EP1572110B1 (de) | 2002-12-20 | 2003-12-09 | Dentalmaterial mit bakteriostatischen und/oder bakteriziden substanzen |
| US10/539,952 US20060159630A1 (en) | 2002-12-20 | 2003-12-09 | Dental material containing bacteristatic and/or bactericidal substances |
| AT03789178T ATE442122T1 (de) | 2002-12-20 | 2003-12-09 | Dentalmaterial mit bakteriostatischen und/oder bakteriziden substanzen |
| PCT/EP2003/013915 WO2004058193A1 (de) | 2002-12-20 | 2003-12-09 | Dentalmaterial mit backteriostatischen und/oder bakteriziden substanzen |
| DE50311901T DE50311901D1 (de) | 2002-12-20 | 2003-12-09 | Dentalmaterial mit bakteriostatischen und/oder bakteriziden substanzen |
| AU2003293804A AU2003293804A1 (en) | 2002-12-20 | 2003-12-09 | Dental material containing bacteriostatic and/or bactericidal substances |
| JP2004562713A JP2006512381A (ja) | 2002-12-20 | 2003-12-09 | 静菌および／または殺菌物質を有する歯科材料 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10261241A DE10261241A1 (de) | 2002-12-20 | 2002-12-20 | Dentalmaterial mit bakteriostatischen und/oder bakteriziden Substanzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10261241A1 true DE10261241A1 (de) | 2004-07-15 |
Family
ID=32519416
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10261241A Ceased DE10261241A1 (de) | 2002-12-20 | 2002-12-20 | Dentalmaterial mit bakteriostatischen und/oder bakteriziden Substanzen |
| DE50311901T Expired - Lifetime DE50311901D1 (de) | 2002-12-20 | 2003-12-09 | Dentalmaterial mit bakteriostatischen und/oder bakteriziden substanzen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE50311901T Expired - Lifetime DE50311901D1 (de) | 2002-12-20 | 2003-12-09 | Dentalmaterial mit bakteriostatischen und/oder bakteriziden substanzen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060159630A1 (enExample) |
| EP (1) | EP1572110B1 (enExample) |
| JP (1) | JP2006512381A (enExample) |
| AT (1) | ATE442122T1 (enExample) |
| AU (1) | AU2003293804A1 (enExample) |
| DE (2) | DE10261241A1 (enExample) |
| WO (1) | WO2004058193A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8933147B2 (en) | 2005-11-17 | 2015-01-13 | 3M Innovative Properties Company | Anti-microbial dental impression material |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040122126A1 (en) * | 2002-12-20 | 2004-06-24 | Dong Wu | Free-radical initiator systems containing enzymes, compositions, and methods |
| US20040120901A1 (en) * | 2002-12-20 | 2004-06-24 | Dong Wu | Dental compositions including enzymes and methods |
| DE102005053954A1 (de) | 2005-11-11 | 2007-05-16 | Ivoclar Vivadent Ag | Verfahren zur Herstellung von im Dentalbereich einsetzbaren Kompositen |
| EP2090280B1 (en) | 2008-02-18 | 2019-10-16 | Coltène/Whaledent AG | Two-component composition for filling an implant abutment |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4222821C2 (de) * | 1992-07-08 | 1994-09-22 | Ivoclar Ag | Modifiziertes Chlorhexidin-Addukt |
| DE19846556A1 (de) * | 1998-10-09 | 2000-04-13 | Degussa | Dentalwerkstoff aufweisend poröse Glaskeramiken, poröse Glaskeramiken, Verfahren und Verwendung |
| DE19937093A1 (de) * | 1999-08-06 | 2001-02-08 | Espe Dental Ag | Adhäsivsysteme III |
| DE19937092A1 (de) * | 1999-08-06 | 2001-02-08 | Espe Dental Ag | Adhäsivsysteme I |
| DE19937091A1 (de) * | 1999-08-06 | 2001-02-22 | Espe Dental Ag | Adhäsivsysteme II |
| DE19849388C2 (de) * | 1998-10-27 | 2001-05-17 | Schott Glas | Bariumfreies röntgenopakes Dentalglas sowie dessen Verwendung |
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- 2003-12-09 JP JP2004562713A patent/JP2006512381A/ja active Pending
- 2003-12-09 AT AT03789178T patent/ATE442122T1/de not_active IP Right Cessation
- 2003-12-09 US US10/539,952 patent/US20060159630A1/en not_active Abandoned
- 2003-12-09 EP EP03789178A patent/EP1572110B1/de not_active Expired - Lifetime
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US8933147B2 (en) | 2005-11-17 | 2015-01-13 | 3M Innovative Properties Company | Anti-microbial dental impression material |
Also Published As
| Publication number | Publication date |
|---|---|
| US20060159630A1 (en) | 2006-07-20 |
| EP1572110A1 (de) | 2005-09-14 |
| JP2006512381A (ja) | 2006-04-13 |
| WO2004058193A1 (de) | 2004-07-15 |
| ATE442122T1 (de) | 2009-09-15 |
| DE50311901D1 (de) | 2009-10-22 |
| AU2003293804A1 (en) | 2004-07-22 |
| EP1572110B1 (de) | 2009-09-09 |
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Owner name: 3M DEUTSCHLAND GMBH, DE Free format text: FORMER OWNER: 3M ESPE AG, 82229 SEEFELD, DE Effective date: 20120514 |
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