DE102008062650B9 - Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu - Google Patents

Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu Download PDF

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Publication number
DE102008062650B9
DE102008062650B9 DE102008062650.3A DE102008062650A DE102008062650B9 DE 102008062650 B9 DE102008062650 B9 DE 102008062650B9 DE 102008062650 A DE102008062650 A DE 102008062650A DE 102008062650 B9 DE102008062650 B9 DE 102008062650B9
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light
beam splitter
camera
section
infrared
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German (de)
English (en)
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DE102008062650A1 (de
DE102008062650B4 (de
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Helge Jess
Dieter Quendt
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Carl Zeiss Meditec AG
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Carl Zeiss Meditec AG
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Priority to DE102008062650.3A priority Critical patent/DE102008062650B9/de
Priority to ES09015577.1T priority patent/ES2563284T3/es
Priority to EP09015577.1A priority patent/EP2199842B1/en
Priority to US12/639,804 priority patent/US8659651B2/en
Priority to JP2009286310A priority patent/JP5646844B2/ja
Publication of DE102008062650A1 publication Critical patent/DE102008062650A1/de
Priority to JP2014182157A priority patent/JP6062405B2/ja
Priority to JP2016165862A priority patent/JP2017021356A/ja
Publication of DE102008062650B4 publication Critical patent/DE102008062650B4/de
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/0012—Surgical microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0064—Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/18—Arrangements with more than one light path, e.g. for comparing two specimens
    • G02B21/20—Binocular arrangements
    • G02B21/22—Stereoscopic arrangements
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G02B27/1006—Beam splitting or combining systems for splitting or combining different wavelengths
    • G02B27/1013—Beam splitting or combining systems for splitting or combining different wavelengths for colour or multispectral image sensors, e.g. splitting an image into monochromatic image components on respective sensors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G02B27/14—Beam splitting or combining systems operating by reflection only
    • G02B27/144—Beam splitting or combining systems operating by reflection only using partially transparent surfaces without spectral selectivity
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G02B27/14—Beam splitting or combining systems operating by reflection only
    • G02B27/145—Beam splitting or combining systems operating by reflection only having sequential partially reflecting surfaces
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G02B27/14—Beam splitting or combining systems operating by reflection only
    • G02B27/149—Beam splitting or combining systems operating by reflection only using crossed beamsplitting surfaces, e.g. cross-dichroic cubes or X-cubes

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Elements Other Than Lenses (AREA)
  • Color Television Image Signal Generators (AREA)
DE102008062650.3A 2008-12-17 2008-12-17 Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu Active DE102008062650B9 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE102008062650.3A DE102008062650B9 (de) 2008-12-17 2008-12-17 Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu
EP09015577.1A EP2199842B1 (en) 2008-12-17 2009-12-16 Surgical microscope for observing an infrared fluorescence and corresponding method
US12/639,804 US8659651B2 (en) 2008-12-17 2009-12-16 Surgical microscope for observing an infrared fluorescence and corresponding method
ES09015577.1T ES2563284T3 (es) 2008-12-17 2009-12-16 Microscopio quirúrgico para observar una fluorescencia infrarroja y método correspondiente
JP2009286310A JP5646844B2 (ja) 2008-12-17 2009-12-17 赤外蛍光を観察するための手術用顕微鏡
JP2014182157A JP6062405B2 (ja) 2008-12-17 2014-09-08 赤外蛍光を観察するための手術用顕微鏡、顕微鏡検査方法、および手術用顕微鏡の使用
JP2016165862A JP2017021356A (ja) 2008-12-17 2016-08-26 赤外蛍光を観察するための手術用顕微鏡、顕微鏡検査方法、および手術用顕微鏡の使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102008062650.3A DE102008062650B9 (de) 2008-12-17 2008-12-17 Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu

Publications (3)

Publication Number Publication Date
DE102008062650A1 DE102008062650A1 (de) 2010-07-15
DE102008062650B4 DE102008062650B4 (de) 2021-08-12
DE102008062650B9 true DE102008062650B9 (de) 2021-10-28

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Country Status (5)

Country Link
US (1) US8659651B2 (https=)
EP (1) EP2199842B1 (https=)
JP (3) JP5646844B2 (https=)
DE (1) DE102008062650B9 (https=)
ES (1) ES2563284T3 (https=)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008029661A1 (de) * 2008-06-24 2009-12-31 Khs Ag Redundante Inspektion
DE102008062650B9 (de) * 2008-12-17 2021-10-28 Carl Zeiss Meditec Ag Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu
US9211058B2 (en) * 2010-07-02 2015-12-15 Intuitive Surgical Operations, Inc. Method and system for fluorescent imaging with background surgical image composed of selective illumination spectra
US10682198B2 (en) 2010-07-02 2020-06-16 Intuitive Surgical Operations, Inc. Method and system for fluorescent imaging with background surgical image composed of selective illumination spectra
DE102010033825B9 (de) * 2010-08-09 2024-04-18 Carl Zeiss Meditec Ag Fluoreszenzbeobachtungssystem und Filtersatz
DE102010044502A1 (de) * 2010-09-06 2012-03-08 Leica Microsystems (Schweiz) Ag Sonderbeleuchtungs-Video-Operations-Stereomikroskop
DE102010044503B4 (de) * 2010-09-06 2017-11-02 Leica Microsystems (Schweiz) Ag Fluoreszenz-Operations-Stereomikroskop
DE102010063960A1 (de) * 2010-12-22 2012-06-28 Carl Zeiss Microlmaging Gmbh Kamera mit einem Farbbildsensor sowie Aufnahmeverfahren mit einer solchen Kamera
DE102011016138A1 (de) * 2011-03-30 2012-10-04 Karl Storz Gmbh & Co. Kg Vorrichtung zur Fluoreszenzdiagnose
DE102011017046A1 (de) * 2011-04-14 2012-10-18 Till Photonics Gmbh Umschaltbare Mikroskopanordnung mit mehreren Detektoren
JP2013003495A (ja) * 2011-06-21 2013-01-07 Mitaka Koki Co Ltd 顕微鏡システム
DE102012000675A1 (de) 2012-01-17 2013-07-18 Bundesrepublik Deutschland, vertr.d.d. Bundesministerium für Wirtschaft und Technologie, d.vertr.d.d. Präsidenten der Physikalisch-Technischen Bundesanstalt Medizinisches Fluoreszenz-Untersuchungssystem
US9371555B2 (en) * 2012-06-01 2016-06-21 Concordia Laboratories Inc. Lighting systems and methods of using lighting systems for in vitro potency assay for photofrin
US9729831B2 (en) * 2012-11-29 2017-08-08 Sony Corporation Wireless surgical loupe
US10273147B2 (en) 2013-07-08 2019-04-30 Motion Engine Inc. MEMS components and method of wafer-level manufacturing thereof
WO2015013827A1 (en) 2013-08-02 2015-02-05 Motion Engine Inc. Mems motion sensor for sub-resonance angular rate sensing
US10451553B2 (en) 2014-04-03 2019-10-22 Hitachi High-Technologies Corporation Fluorescence spectrometer
US20170030788A1 (en) 2014-04-10 2017-02-02 Motion Engine Inc. Mems pressure sensor
US11674803B2 (en) 2014-06-02 2023-06-13 Motion Engine, Inc. Multi-mass MEMS motion sensor
US11287486B2 (en) 2014-12-09 2022-03-29 Motion Engine, Inc. 3D MEMS magnetometer and associated methods
DE102014118382B4 (de) 2014-12-11 2020-07-02 Carl Zeiss Meditec Ag Optisches Beobachtungsgerät und Verfahren zum Betreiben eines optischen Beobachtungsgerätes.
US10407299B2 (en) 2015-01-15 2019-09-10 Motion Engine Inc. 3D MEMS device with hermetic cavity
US10295815B2 (en) 2015-02-09 2019-05-21 Arizona Board Of Regents On Behalf Of The University Of Arizona Augmented stereoscopic microscopy
DE102015202605B4 (de) 2015-02-12 2017-03-09 Carl Zeiss Meditec Ag Visualisierungssystem
DE102015203844A1 (de) * 2015-03-04 2016-09-08 Carl Zeiss Meditec Ag Optiksystem und Operationsmikroskop
CN104793326A (zh) * 2015-04-30 2015-07-22 麦克奥迪实业集团有限公司 一种具有同轴照明效果的体视显微镜
JP6859554B2 (ja) 2015-06-02 2021-04-14 ライカ ミクロジュステムス（シュヴァイツ）アーゲー 観察補助装置、情報処理方法、およびプログラム
US10063850B2 (en) * 2015-06-23 2018-08-28 Mitaka Kohki Co., Ltd. Surgical stereoscopic observation apparatus
JP2017006620A (ja) * 2015-06-23 2017-01-12 三鷹光器株式会社 手術用立体観察装置
EP3322329A1 (en) * 2015-07-14 2018-05-23 Tsme, Llc Surgical optical system with heads up display
DE102016104439A1 (de) * 2015-08-31 2017-03-02 Carl Zeiss Meditec Ag Bildaufnahmeanordnung, optisches Beobachtungsgerät und Verfahren zum Aufnehmen von Bildern
DE102015216570A1 (de) * 2015-08-31 2016-11-03 Carl Zeiss Meditec Ag Mikroskopiesystem
DE102017109021B4 (de) * 2016-05-11 2022-10-27 Carl Zeiss Meditec Ag System für das stereoskopische Visualisieren eines Objektbereichs sowie Objektbereich-Visualisierungsverfahren
US10299880B2 (en) * 2017-04-24 2019-05-28 Truevision Systems, Inc. Stereoscopic visualization camera and platform
WO2019116165A1 (en) 2017-12-12 2019-06-20 Novartis Ag Combined near infrared imaging and visible imaging in a compact microscope stack
RU2687800C1 (ru) * 2018-04-18 2019-05-16 Илья Николаевич Дмитриев Цифровой стереомикроскоп
DE102018110643B3 (de) 2018-05-03 2019-07-25 Carl Zeiss Meditec Ag Stereo-Mikroskop und Verfahren zur Stereomikroskopie
CN112188872A (zh) * 2018-05-24 2021-01-05 学校法人庆应义塾 手术用观察系统
KR102698248B1 (ko) 2018-08-10 2024-08-23 삼성디스플레이 주식회사 표시 패널 검사 장치
KR102321416B1 (ko) * 2019-03-19 2021-11-03 한국광기술원 증강현실 구현을 위한 빔 스플리터 및 이를 포함한 증강현실 광학계
JP7552613B2 (ja) 2019-11-28 2024-09-18 ソニーグループ株式会社 手術顕微鏡システム、および顕微鏡カメラアダプタ
DE102020123365A1 (de) * 2020-09-08 2022-03-10 Munich Surgical Imaging GmbH Operationsmikroskop mit mindestens zwei Kameraeinrichtungen
EP4009095A1 (en) * 2020-12-02 2022-06-08 Leica Instruments (Singapore) Pte. Ltd. Hybrid microscope
KR102549929B1 (ko) * 2021-08-05 2023-06-30 주식회사 메타플바이오 3차원 광 검출 장치
DE102022116292A1 (de) * 2022-06-30 2024-01-04 Karl Storz Se & Co. Kg Strahlteilungsvorrichtung für einen distalen Endabschnitt eines Endoskops, Objektivsystem und Endoskop
DE102022125852A1 (de) * 2022-10-06 2024-04-11 Karl Storz Se & Co. Kg Medizinische Bildgebungsvorrichtung und Verfahren zur medizinischen Bildgebung
US12038630B1 (en) 2022-11-18 2024-07-16 Designs For Vision, Inc. Telescopic image capture/recording device
US12332507B2 (en) * 2022-11-18 2025-06-17 Designs For Vision, Inc. Examination/visualization/collection system with light enhancement
EP4403089A1 (de) * 2023-01-17 2024-07-24 Erbe Elektromedizin GmbH Visualisierungseinrichtung
WO2024158609A1 (en) * 2023-01-23 2024-08-02 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Hyper-throughput, multiplex, single molecule imaging platform
DE102024107271B3 (de) * 2024-03-14 2025-05-22 Jenoptik Optical Systems Gmbh Lichtleiteinrichtung und Verfahren zum Betreiben einer Lichtleiteinrichtung

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2254417A (en) 1991-04-05 1992-10-07 Bijan Jouza Photodynamic laser detection for cancer diagnosis
WO1994018593A1 (en) 1993-02-12 1994-08-18 Medical Research Council Detecting means for a scanning optical microscope
US5507287A (en) 1991-05-08 1996-04-16 Xillix Technologies Corporation Endoscopic imaging system for diseased tissue
WO1999001749A1 (en) 1997-07-03 1999-01-14 Smith & Nephew, Inc. Fluorescence imaging system
DE69518915T2 (de) 1994-03-28 2001-04-19 Xillix Technologies Corp., Richmond Verfahren und vorrichtung zur bilderzeugung von erkranktem gewebe unter verwendung der integrierten autofluoreszenz
DE69623523T2 (de) 1995-04-06 2003-07-31 Becton Dickinson And Co., Franklin Lakes Analysator von fluoreszierenden Teilchen mit Verzögerungsschaltung zur Ermöglichung der Subtraktion von aus unterschiedlichen Orten stammenden Fluoreszenzpulsen
DE10251151A1 (de) 2002-10-31 2004-05-13 Leica Microsystems Heidelberg Gmbh Konfokales Rastermikroskop zum Abbilden eines Lumineszenzobjekts und Verfahren zum Abbilden eines Lumineszenzobjekts
US6899675B2 (en) 2002-01-15 2005-05-31 Xillix Technologies Corp. Fluorescence endoscopy video systems with no moving parts in the camera
DE102005005253A1 (de) 2004-02-11 2005-11-17 Carl Zeiss Ag Untersuchungssystem und Untersuchungsverfahren
EP1731087A2 (en) 2000-07-14 2006-12-13 Xillix Technologies Corp. Compact fluorescent endoscopy video system
DE69834963T2 (de) 1997-04-09 2007-01-25 1192062 Alberta Ltd., Calgary Farbumsetzendes UV-Mikroskop
US20070077609A1 (en) 2005-03-11 2007-04-05 Gambhir Sanjiv S Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof
EP2075616A1 (de) 2007-12-28 2009-07-01 Möller-Wedel GmbH Vorrichtung mit einer Kamera und einer Einrichtung zum Abbilden und Projizieren des aufgenommen Bildes

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045772A (en) * 1974-04-29 1977-08-30 Geometric Data Corporation Automatic focusing system
JPH0282876A (ja) * 1988-09-20 1990-03-23 Sony Corp カラーモード・赤外モード共用ビデオカメラ
JPH06141247A (ja) * 1992-10-22 1994-05-20 Sony Corp 固体撮像装置
JPH08275182A (ja) * 1995-03-28 1996-10-18 Canon Inc カラーモード・赤外モード共用型テレビカメラ
US5808329A (en) 1996-07-15 1998-09-15 Raytheon Company Low light level imager with extended wavelength response employing atomic bonded (fused) semiconductor materials
EP1403675B1 (en) 1997-04-09 2006-06-14 1192062 Alberta Limited Colour translating UV microscope
US6198147B1 (en) * 1998-07-06 2001-03-06 Intel Corporation Detecting infrared and visible light
US6826424B1 (en) * 2000-12-19 2004-11-30 Haishan Zeng Methods and apparatus for fluorescence and reflectance imaging and spectroscopy and for contemporaneous measurements of electromagnetic radiation with multiple measuring devices
JP2003270129A (ja) * 2002-03-18 2003-09-25 Yokogawa Electric Corp 画像測定装置
DE10362402B3 (de) * 2002-08-28 2022-03-03 Carl Zeiss Meditec Ag Mikroskopiesystem und Mikroskopieverfahren
AU2003272531A1 (en) 2003-09-15 2005-04-27 Beth Israel Deaconess Medical Center Medical imaging systems
US8556806B2 (en) * 2004-09-24 2013-10-15 Vivid Medical, Inc. Wavelength multiplexing endoscope
US7508507B2 (en) * 2004-10-12 2009-03-24 Leica Microsystems Cms Gmbh Device for selecting and detecting at least two spectral regions of a light beam
US7526116B2 (en) * 2006-01-19 2009-04-28 Luigi Armogida Automated microscopic sperm identification
DE102006004232C5 (de) * 2006-01-30 2013-08-01 Carl Zeiss Surgical Gmbh Mikroskopiesystem
JP4971816B2 (ja) * 2007-02-05 2012-07-11 三洋電機株式会社 撮像装置
DE102008004596A1 (de) 2008-01-16 2008-06-19 Carl Zeiss Surgical Gmbh Fluoreszenzmikroskop und Beleuchtungsystem hierfür
US7645971B2 (en) * 2008-01-18 2010-01-12 Ffei Limited Image scanning apparatus and method
DE102008062650B9 (de) * 2008-12-17 2021-10-28 Carl Zeiss Meditec Ag Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2254417A (en) 1991-04-05 1992-10-07 Bijan Jouza Photodynamic laser detection for cancer diagnosis
US5507287A (en) 1991-05-08 1996-04-16 Xillix Technologies Corporation Endoscopic imaging system for diseased tissue
WO1994018593A1 (en) 1993-02-12 1994-08-18 Medical Research Council Detecting means for a scanning optical microscope
DE69518915T2 (de) 1994-03-28 2001-04-19 Xillix Technologies Corp., Richmond Verfahren und vorrichtung zur bilderzeugung von erkranktem gewebe unter verwendung der integrierten autofluoreszenz
DE69623523T2 (de) 1995-04-06 2003-07-31 Becton Dickinson And Co., Franklin Lakes Analysator von fluoreszierenden Teilchen mit Verzögerungsschaltung zur Ermöglichung der Subtraktion von aus unterschiedlichen Orten stammenden Fluoreszenzpulsen
DE69834963T2 (de) 1997-04-09 2007-01-25 1192062 Alberta Ltd., Calgary Farbumsetzendes UV-Mikroskop
WO1999001749A1 (en) 1997-07-03 1999-01-14 Smith & Nephew, Inc. Fluorescence imaging system
EP1731087A2 (en) 2000-07-14 2006-12-13 Xillix Technologies Corp. Compact fluorescent endoscopy video system
US6899675B2 (en) 2002-01-15 2005-05-31 Xillix Technologies Corp. Fluorescence endoscopy video systems with no moving parts in the camera
DE10251151A1 (de) 2002-10-31 2004-05-13 Leica Microsystems Heidelberg Gmbh Konfokales Rastermikroskop zum Abbilden eines Lumineszenzobjekts und Verfahren zum Abbilden eines Lumineszenzobjekts
DE102005005253A1 (de) 2004-02-11 2005-11-17 Carl Zeiss Ag Untersuchungssystem und Untersuchungsverfahren
US20070077609A1 (en) 2005-03-11 2007-04-05 Gambhir Sanjiv S Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof
EP2075616A1 (de) 2007-12-28 2009-07-01 Möller-Wedel GmbH Vorrichtung mit einer Kamera und einer Einrichtung zum Abbilden und Projizieren des aufgenommen Bildes

Also Published As

Publication number Publication date
DE102008062650A1 (de) 2010-07-15
JP2010142641A (ja) 2010-07-01
JP2015061598A (ja) 2015-04-02
JP6062405B2 (ja) 2017-01-18
US20100182418A1 (en) 2010-07-22
US8659651B2 (en) 2014-02-25
DE102008062650B4 (de) 2021-08-12
JP2017021356A (ja) 2017-01-26
JP5646844B2 (ja) 2014-12-24
ES2563284T3 (es) 2016-03-14
EP2199842B1 (en) 2015-12-16
EP2199842A1 (en) 2010-06-23

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