DE10152306A1 - 2-Acylindolderivate mit neuen therapeutisch wertvollen Eigenschaften - Google Patents
2-Acylindolderivate mit neuen therapeutisch wertvollen EigenschaftenInfo
- Publication number
- DE10152306A1 DE10152306A1 DE10152306A DE10152306A DE10152306A1 DE 10152306 A1 DE10152306 A1 DE 10152306A1 DE 10152306 A DE10152306 A DE 10152306A DE 10152306 A DE10152306 A DE 10152306A DE 10152306 A1 DE10152306 A1 DE 10152306A1
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- branched
- straight
- chain
- methoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10152306A DE10152306A1 (de) | 2001-10-26 | 2001-10-26 | 2-Acylindolderivate mit neuen therapeutisch wertvollen Eigenschaften |
PCT/EP2002/011883 WO2003037861A1 (fr) | 2001-10-26 | 2002-10-24 | Utilisation de 2-acylindoles pour traiter des tumeurs |
JP2003540143A JP2005516895A (ja) | 2001-10-26 | 2002-10-24 | 腫瘍の治療のための2−アシルインドールの使用 |
EP02802302A EP1442015A1 (fr) | 2001-10-26 | 2002-10-24 | Utilisation de 2-acylindoles pour traiter des tumeurs |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10152306A DE10152306A1 (de) | 2001-10-26 | 2001-10-26 | 2-Acylindolderivate mit neuen therapeutisch wertvollen Eigenschaften |
Publications (2)
Publication Number | Publication Date |
---|---|
DE10152306A1 true DE10152306A1 (de) | 2003-07-24 |
DE10152306A8 DE10152306A8 (de) | 2004-07-08 |
Family
ID=7703459
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10152306A Withdrawn DE10152306A1 (de) | 2001-10-26 | 2001-10-26 | 2-Acylindolderivate mit neuen therapeutisch wertvollen Eigenschaften |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1442015A1 (fr) |
JP (1) | JP2005516895A (fr) |
DE (1) | DE10152306A1 (fr) |
WO (1) | WO2003037861A1 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200503738A (en) * | 2003-07-16 | 2005-02-01 | Tzu Chi Buddhist General Hospital | Method for extracting antineoplastic components from bupleurum scorzonerifolium |
FR2857966A1 (fr) * | 2003-07-24 | 2005-01-28 | Aventis Pharma Sa | Produits aryl-heteroaromatiques, compositions les contenant et utilisation |
GB0330042D0 (en) * | 2003-12-24 | 2004-01-28 | Pharmacia Italia Spa | Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions them |
GB0330043D0 (en) * | 2003-12-24 | 2004-01-28 | Pharmacia Italia Spa | Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them |
WO2005097129A2 (fr) * | 2004-04-05 | 2005-10-20 | Takeda Pharmaceutical Company Limited | Compose de 6-azaindole |
KR20070034049A (ko) | 2004-06-09 | 2007-03-27 | 글락소 그룹 리미티드 | 피롤로피리딘 유도체 |
US20070155738A1 (en) | 2005-05-20 | 2007-07-05 | Alantos Pharmaceuticals, Inc. | Heterobicyclic metalloprotease inhibitors |
US20060280787A1 (en) * | 2005-06-14 | 2006-12-14 | Baxter International Inc. | Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof |
DE102009049211A1 (de) * | 2009-10-13 | 2011-04-28 | Merck Patent Gmbh | Sulfoxide |
WO2013112878A1 (fr) * | 2012-01-26 | 2013-08-01 | The Penn State Research Foundation | Compositions de modulation de mcl-1 |
US9738637B2 (en) * | 2013-03-12 | 2017-08-22 | Celgene Quantical Research, Inc. | Histone demethylase inhibitors |
JP6820854B2 (ja) * | 2015-01-18 | 2021-01-27 | エスアールアイ インターナショナルSRI International | Map4k4(hgk)インヒビター |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3838167A (en) * | 1972-08-01 | 1974-09-24 | Lilly Co Eli | Process for preparing indoles |
GB1472342A (en) * | 1974-01-25 | 1977-05-04 | Ciba Geigy Ag | Derivatives of 2-2-pyridylcarbonyl-indole |
GB2283745A (en) * | 1993-11-12 | 1995-05-17 | Merck Frosst Canada Inc | Pharmaceutically active N-acylindoles |
WO1999005104A1 (fr) * | 1997-07-23 | 1999-02-04 | Pfizer Pharmaceuticals Inc. | Composes d'indole en tant qu'inhibiteurs de cox-2 |
WO2001082909A2 (fr) * | 2000-04-28 | 2001-11-08 | Baxter Healthcare Sa | Derives de 2-acyl-indole et leur utilisation comme agents antitumoraux |
-
2001
- 2001-10-26 DE DE10152306A patent/DE10152306A1/de not_active Withdrawn
-
2002
- 2002-10-24 JP JP2003540143A patent/JP2005516895A/ja not_active Withdrawn
- 2002-10-24 EP EP02802302A patent/EP1442015A1/fr not_active Withdrawn
- 2002-10-24 WO PCT/EP2002/011883 patent/WO2003037861A1/fr not_active Application Discontinuation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3838167A (en) * | 1972-08-01 | 1974-09-24 | Lilly Co Eli | Process for preparing indoles |
GB1472342A (en) * | 1974-01-25 | 1977-05-04 | Ciba Geigy Ag | Derivatives of 2-2-pyridylcarbonyl-indole |
GB2283745A (en) * | 1993-11-12 | 1995-05-17 | Merck Frosst Canada Inc | Pharmaceutically active N-acylindoles |
WO1999005104A1 (fr) * | 1997-07-23 | 1999-02-04 | Pfizer Pharmaceuticals Inc. | Composes d'indole en tant qu'inhibiteurs de cox-2 |
WO2001082909A2 (fr) * | 2000-04-28 | 2001-11-08 | Baxter Healthcare Sa | Derives de 2-acyl-indole et leur utilisation comme agents antitumoraux |
Also Published As
Publication number | Publication date |
---|---|
EP1442015A1 (fr) | 2004-08-04 |
WO2003037861A1 (fr) | 2003-05-08 |
DE10152306A8 (de) | 2004-07-08 |
JP2005516895A (ja) | 2005-06-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
OM8 | Search report available as to paragraph 43 lit. 1 sentence 1 patent law | ||
8196 | Reprint of faulty title page (publication) german patentblatt: part 1a6 | ||
OM8 | Search report available as to paragraph 43 lit. 1 sentence 1 patent law | ||
8127 | New person/name/address of the applicant |
Owner name: BAXTER HEALTHCARE S.A., WALLISELLEN, CH |
|
8128 | New person/name/address of the agent |
Representative=s name: BACHMANN, J., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., |
|
8128 | New person/name/address of the agent |
Representative=s name: FREISE, B., RECHTSANW., 85716 UNTERSCHLEISSHEIM |
|
8139 | Disposal/non-payment of the annual fee |