DE10058240A1 - Verfahren und Vorrichtung zur Herstellung biologischer Prothesen - Google Patents

Verfahren und Vorrichtung zur Herstellung biologischer Prothesen

Info

Publication number
DE10058240A1
DE10058240A1 DE10058240A DE10058240A DE10058240A1 DE 10058240 A1 DE10058240 A1 DE 10058240A1 DE 10058240 A DE10058240 A DE 10058240A DE 10058240 A DE10058240 A DE 10058240A DE 10058240 A1 DE10058240 A1 DE 10058240A1
Authority
DE
Germany
Prior art keywords
cell
flow
cells
bioreactor
ring line
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10058240A
Other languages
German (de)
English (en)
Inventor
Wolfgang Konertz
Pascal Dohmen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AutoTissue GmbH
Original Assignee
AutoTissue GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AutoTissue GmbH filed Critical AutoTissue GmbH
Priority to DE10058240A priority Critical patent/DE10058240A1/de
Priority to PCT/DE2001/003632 priority patent/WO2002040076A1/fr
Priority to AU2002210367A priority patent/AU2002210367A1/en
Priority to DE10194891T priority patent/DE10194891D2/de
Publication of DE10058240A1 publication Critical patent/DE10058240A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/062—Apparatus for the production of blood vessels made from natural tissue or with layers of living cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2415—Manufacturing methods

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
DE10058240A 2000-11-17 2000-11-17 Verfahren und Vorrichtung zur Herstellung biologischer Prothesen Withdrawn DE10058240A1 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE10058240A DE10058240A1 (de) 2000-11-17 2000-11-17 Verfahren und Vorrichtung zur Herstellung biologischer Prothesen
PCT/DE2001/003632 WO2002040076A1 (fr) 2000-11-17 2001-09-19 Procede et dispositif pour produire des protheses biologiques
AU2002210367A AU2002210367A1 (en) 2000-11-17 2001-09-19 Method and device for producing biological prostheses
DE10194891T DE10194891D2 (de) 2000-11-17 2001-09-19 Verfahren und Vorrichtung zur Herstellung biologischer Prothesen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10058240A DE10058240A1 (de) 2000-11-17 2000-11-17 Verfahren und Vorrichtung zur Herstellung biologischer Prothesen

Publications (1)

Publication Number Publication Date
DE10058240A1 true DE10058240A1 (de) 2002-05-29

Family

ID=7664431

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10058240A Withdrawn DE10058240A1 (de) 2000-11-17 2000-11-17 Verfahren und Vorrichtung zur Herstellung biologischer Prothesen
DE10194891T Expired - Fee Related DE10194891D2 (de) 2000-11-17 2001-09-19 Verfahren und Vorrichtung zur Herstellung biologischer Prothesen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE10194891T Expired - Fee Related DE10194891D2 (de) 2000-11-17 2001-09-19 Verfahren und Vorrichtung zur Herstellung biologischer Prothesen

Country Status (3)

Country Link
AU (1) AU2002210367A1 (fr)
DE (2) DE10058240A1 (fr)
WO (1) WO2002040076A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10130512A1 (de) * 2001-06-25 2003-02-13 Bionethos Gmbh Vorrichtung zur Druckperfusion für das Züchten und/oder für das Behandeln von Zellen
DE10211106A1 (de) * 2002-03-12 2003-10-02 Bio En Consult Innovations Und Verfahren und Vorrichtung zur Verbesserung der Sauerstoffzufuhr für Zellkulturen in Bioreaktoren
WO2005107642A1 (fr) * 2004-05-07 2005-11-17 University College Cardiff Consultants Limited Structures tissulaires tubulaires produites par genie tissulaire
DE102009008923A1 (de) * 2009-02-13 2010-08-26 Hennig, Jörn, Dipl.-Ing. Zellbesiedelungskammer

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10258121B3 (de) * 2002-12-06 2004-03-18 Auto Tissue Gmbh Verfahren zur Herstellung von Bioprothesen
EP1693025A1 (fr) 2005-02-17 2006-08-23 Universität Zürich Procédé pour la production d'une prothèse par génie tissulaire

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0320441A1 (fr) * 1987-12-07 1989-06-14 GebràœDer Sulzer Aktiengesellschaft Appareil et procédé de conditionnement d'un support en plastique recouvert de cellules vivantes
US5613982A (en) * 1994-03-14 1997-03-25 Cryolife, Inc. Method of preparing transplant tissue to reduce immunogenicity upon implantation
DE19919625A1 (de) * 1999-04-29 2000-11-30 Hoerstrup Simon Philipp In-vitro-Verfahren zum Herstellen einer homologen Herzklappe

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU700911B2 (en) * 1994-09-12 1999-01-14 Advanced Tissue Sciences, Inc. Three-dimensional human cell cultures on cardiac valve frameworks and their uses
US5846828A (en) * 1995-06-07 1998-12-08 Advanced Tissue Sciences Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing tissue, synthetic, or mechanical heart valves orvalve segments
EP0989867B1 (fr) * 1997-06-27 2002-04-24 BADER, Augustinus Transplant biosynthetique et son procede de production
EP1140241B1 (fr) * 1998-12-21 2004-04-14 VasoTissue Technologies GmbH Protheses cardiovasculaires a surface revetue d'une couche stable de cellules endotheliales
DE19915610A1 (de) * 1999-04-07 2000-10-19 Augustinus Bader Verfahren zur Besiedlung von Substraten mit biologischen Zellen und dafür verwendbare Besiedlungsvorrichtungen
DE19938518A1 (de) * 1999-04-23 2000-10-26 Vascular Biotech Gmbh Gewebekultursystem zur Epithelialisierung bzw. Endothelialisierung und zur funktionellen Untersuchung und Anlieferung natürlichen oder künstlicher Hohlorgane bzw. Gefäße unter kontrollierbaren Sterilbedingungen für chirurgische Implantationszwecke

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0320441A1 (fr) * 1987-12-07 1989-06-14 GebràœDer Sulzer Aktiengesellschaft Appareil et procédé de conditionnement d'un support en plastique recouvert de cellules vivantes
US5613982A (en) * 1994-03-14 1997-03-25 Cryolife, Inc. Method of preparing transplant tissue to reduce immunogenicity upon implantation
DE19919625A1 (de) * 1999-04-29 2000-11-30 Hoerstrup Simon Philipp In-vitro-Verfahren zum Herstellen einer homologen Herzklappe

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10130512A1 (de) * 2001-06-25 2003-02-13 Bionethos Gmbh Vorrichtung zur Druckperfusion für das Züchten und/oder für das Behandeln von Zellen
DE10130512B4 (de) * 2001-06-25 2007-08-16 Bionethos Holding Gmbh Vorrichtung zur Druckperfusion für das Züchten und/oder für das Behandeln von Zellen
US7378271B2 (en) 2001-06-25 2008-05-27 Augustinus Bader Device for pressurized perfusion especially for culturing and/or treating cells
US7682820B2 (en) 2001-06-25 2010-03-23 Augustinus Bader Device for pressurized perfusion especially for culturing and/or treating cells
DE10211106A1 (de) * 2002-03-12 2003-10-02 Bio En Consult Innovations Und Verfahren und Vorrichtung zur Verbesserung der Sauerstoffzufuhr für Zellkulturen in Bioreaktoren
DE10211106B4 (de) * 2002-03-12 2004-12-09 Bio-Energie-Consult Innovations- Und Technologie Gmbh Verfahren zur Verbesserung der Sauerstoffzufuhr für Zellkulturen in Bioreaktoren
WO2005107642A1 (fr) * 2004-05-07 2005-11-17 University College Cardiff Consultants Limited Structures tissulaires tubulaires produites par genie tissulaire
GB2431666A (en) * 2004-05-07 2007-05-02 Univ Cardiff Engineered tubular tissue structures
DE102009008923A1 (de) * 2009-02-13 2010-08-26 Hennig, Jörn, Dipl.-Ing. Zellbesiedelungskammer
DE102009008923B4 (de) * 2009-02-13 2011-05-05 Hennig, Jörn, Dipl.-Ing. Zellbesiedelungskammer

Also Published As

Publication number Publication date
DE10194891D2 (de) 2004-01-15
WO2002040076A1 (fr) 2002-05-23
AU2002210367A1 (en) 2002-05-27

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8130 Withdrawal