DD283141A5 - Verfahren zur herstellung kondensierter diazepinone - Google Patents

Verfahren zur herstellung kondensierter diazepinone Download PDF

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Publication number
DD283141A5
DD283141A5 DD88320971A DD32097188A DD283141A5 DD 283141 A5 DD283141 A5 DD 283141A5 DD 88320971 A DD88320971 A DD 88320971A DD 32097188 A DD32097188 A DD 32097188A DD 283141 A5 DD283141 A5 DD 283141A5
Authority
DD
German Democratic Republic
Prior art keywords
general formula
group
atom
dihydro
carbon atoms
Prior art date
Application number
DD88320971A
Other languages
German (de)
English (en)
Inventor
Wolfgang Eberlein
Wolfhard Engel
Guenter Trummlitz
Gerhard Mihm
Norbert Mayer
Henri Doods
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ��K@����@������@������������@���@�������������@�������k�� filed Critical ��K@����@������@������������@���@�������������@�������k��
Publication of DD283141A5 publication Critical patent/DD283141A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DD88320971A 1987-10-23 1988-10-21 Verfahren zur herstellung kondensierter diazepinone DD283141A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873735895 DE3735895A1 (de) 1987-10-23 1987-10-23 Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
DD283141A5 true DD283141A5 (de) 1990-10-03

Family

ID=6338927

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88320971A DD283141A5 (de) 1987-10-23 1988-10-21 Verfahren zur herstellung kondensierter diazepinone

Country Status (16)

Country Link
US (1) US5175158A (fi)
EP (1) EP0312895A3 (fi)
JP (1) JPH0660172B2 (fi)
KR (1) KR890006646A (fi)
AU (1) AU609530B2 (fi)
CA (1) CA1321996C (fi)
DD (1) DD283141A5 (fi)
DE (1) DE3735895A1 (fi)
DK (1) DK586188A (fi)
FI (1) FI87073C (fi)
HU (1) HU199471B (fi)
IL (1) IL88121A (fi)
NO (1) NO167146C (fi)
NZ (1) NZ226681A (fi)
PT (1) PT88808B (fi)
ZA (1) ZA887877B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
US5366972A (en) * 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
CA2019812C (en) * 1989-06-28 2000-11-21 Gunther Schmidt (Deceased) Novel 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-ones and their use in the prevention or treatment of aids
CA2030056C (en) * 1989-11-17 1995-10-17 Karl D. Hargrave 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines and their use in the prevention or treatment of hiv infection
IE912239A1 (en) * 1990-07-24 1992-01-29 Akzo Nv Tetrahydropyridinyldibenzazepine derivatives
DE4112014A1 (de) * 1991-04-12 1992-10-15 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung
US5610155A (en) * 1992-04-09 1997-03-11 Dr. Karl Thomae Gmbh Condensed diazepinones, processes for preparing them and agents containing these compounds for treating diseases of the central nervous system and for promoting cerebral blood circulation
DK0693070T3 (da) * 1993-04-05 2002-11-11 Pharmaceutical Discovery Corp Pyrido[2,3-b][1,4]benzodiazepinoner som M2-receptorligand til behandling af neurologiske lidelser
US6316623B1 (en) * 1998-08-21 2001-11-13 Isis Pharmaceuticals, Inc. Ethylenediamine compound libraries
WO2004011430A1 (ja) * 2002-07-25 2004-02-05 Yamanouchi Pharmaceutical Co., Ltd. ナトリウムチャネル阻害剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3235795A1 (de) * 1982-09-28 1984-03-29 Dr. Karl Thomae Gmbh, 7950 Biberach Neues verfahren zur herstellung von 5,11-dihydro-11-((4-methyl-1-piperazinyl)- acetyl)- 6h-pyrido(2,3-b)(1,4)- benzodiazepin-6-on
DE3409237A1 (de) * 1984-03-14 1985-09-19 Dr. Karl Thomae Gmbh, 7950 Biberach Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
DK586188D0 (da) 1988-10-21
JPH01230580A (ja) 1989-09-14
ZA887877B (en) 1990-06-27
HU199471B (en) 1990-02-28
JPH0660172B2 (ja) 1994-08-10
EP0312895A2 (de) 1989-04-26
FI87073B (fi) 1992-08-14
AU609530B2 (en) 1991-05-02
IL88121A (en) 1993-06-10
NO167146C (no) 1991-10-09
CA1321996C (en) 1993-09-07
NO884698D0 (no) 1988-10-21
PT88808B (pt) 1993-01-29
IL88121A0 (en) 1989-06-30
AU2412288A (en) 1989-04-27
NO167146B (no) 1991-07-01
NO884698L (no) 1989-04-24
HUT48629A (en) 1989-06-28
DK586188A (da) 1989-04-24
FI884863A (fi) 1989-04-24
DE3735895A1 (de) 1989-05-03
FI884863A0 (fi) 1988-10-21
KR890006646A (ko) 1989-06-15
US5175158A (en) 1992-12-29
FI87073C (fi) 1992-11-25
NZ226681A (en) 1991-06-25
EP0312895A3 (de) 1990-08-16

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ENJ Ceased due to non-payment of renewal fee