NO884698L - Analogifremgangsmaate for fremstilling av terapeutisk aktive kondenserte diazepinoner. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive kondenserte diazepinoner.

Info

Publication number
NO884698L
NO884698L NO88884698A NO884698A NO884698L NO 884698 L NO884698 L NO 884698L NO 88884698 A NO88884698 A NO 88884698A NO 884698 A NO884698 A NO 884698A NO 884698 L NO884698 L NO 884698L
Authority
NO
Norway
Prior art keywords
preparation
therapeutic active
analogy procedure
condensed diazepinones
active condensed
Prior art date
Application number
NO88884698A
Other languages
English (en)
Other versions
NO167146C (no
NO884698D0 (no
NO167146B (no
Inventor
Wolfgang Eberlein
Wolfhard Engel
Guenter Trummlitz
Gerhard Mihm
Norbert Mayer
Henri Doods
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO884698D0 publication Critical patent/NO884698D0/no
Publication of NO884698L publication Critical patent/NO884698L/no
Publication of NO167146B publication Critical patent/NO167146B/no
Publication of NO167146C publication Critical patent/NO167146C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO884698A 1987-10-23 1988-10-21 Analogifremgangsmaate for fremstilling av terapeutisk aktive kondenserte diazepinoner. NO167146C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873735895 DE3735895A1 (de) 1987-10-23 1987-10-23 Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (4)

Publication Number Publication Date
NO884698D0 NO884698D0 (no) 1988-10-21
NO884698L true NO884698L (no) 1989-04-24
NO167146B NO167146B (no) 1991-07-01
NO167146C NO167146C (no) 1991-10-09

Family

ID=6338927

Family Applications (1)

Application Number Title Priority Date Filing Date
NO884698A NO167146C (no) 1987-10-23 1988-10-21 Analogifremgangsmaate for fremstilling av terapeutisk aktive kondenserte diazepinoner.

Country Status (16)

Country Link
US (1) US5175158A (no)
EP (1) EP0312895A3 (no)
JP (1) JPH0660172B2 (no)
KR (1) KR890006646A (no)
AU (1) AU609530B2 (no)
CA (1) CA1321996C (no)
DD (1) DD283141A5 (no)
DE (1) DE3735895A1 (no)
DK (1) DK586188A (no)
FI (1) FI87073C (no)
HU (1) HU199471B (no)
IL (1) IL88121A (no)
NO (1) NO167146C (no)
NZ (1) NZ226681A (no)
PT (1) PT88808B (no)
ZA (1) ZA887877B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
US5366972A (en) * 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
ATE103918T1 (de) * 1989-06-28 1994-04-15 Boehringer Ingelheim Pharma 5,11-dihydro-6h-dipyrido(3,2-b:2',3'e>(1,4>diazepin-6-one und -thione und ihre verwendung bei der aids-vorbeugung oder behandlung.
CA2030056C (en) * 1989-11-17 1995-10-17 Karl D. Hargrave 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines and their use in the prevention or treatment of hiv infection
IE912239A1 (en) * 1990-07-24 1992-01-29 Akzo Nv Tetrahydropyridinyldibenzazepine derivatives
DE4112014A1 (de) * 1991-04-12 1992-10-15 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung
US5610155A (en) * 1992-04-09 1997-03-11 Dr. Karl Thomae Gmbh Condensed diazepinones, processes for preparing them and agents containing these compounds for treating diseases of the central nervous system and for promoting cerebral blood circulation
ATE221067T1 (de) * 1993-04-05 2002-08-15 Pharmaceutical Discovery Corp Pyrido(2,3-b)(1,4)benzodiazepinone als m2- rezeptorligand zur behandlung neurologischer störungen
US6316623B1 (en) * 1998-08-21 2001-11-13 Isis Pharmaceuticals, Inc. Ethylenediamine compound libraries
WO2004011430A1 (ja) * 2002-07-25 2004-02-05 Yamanouchi Pharmaceutical Co., Ltd. ナトリウムチャネル阻害剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3235795A1 (de) * 1982-09-28 1984-03-29 Dr. Karl Thomae Gmbh, 7950 Biberach Neues verfahren zur herstellung von 5,11-dihydro-11-((4-methyl-1-piperazinyl)- acetyl)- 6h-pyrido(2,3-b)(1,4)- benzodiazepin-6-on
DE3409237A1 (de) * 1984-03-14 1985-09-19 Dr. Karl Thomae Gmbh, 7950 Biberach Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
JPH0660172B2 (ja) 1994-08-10
DD283141A5 (de) 1990-10-03
FI884863A (fi) 1989-04-24
FI87073C (fi) 1992-11-25
EP0312895A3 (de) 1990-08-16
ZA887877B (en) 1990-06-27
JPH01230580A (ja) 1989-09-14
KR890006646A (ko) 1989-06-15
EP0312895A2 (de) 1989-04-26
FI87073B (fi) 1992-08-14
NO167146C (no) 1991-10-09
NO884698D0 (no) 1988-10-21
CA1321996C (en) 1993-09-07
IL88121A0 (en) 1989-06-30
AU2412288A (en) 1989-04-27
DE3735895A1 (de) 1989-05-03
DK586188D0 (da) 1988-10-21
NO167146B (no) 1991-07-01
NZ226681A (en) 1991-06-25
PT88808B (pt) 1993-01-29
FI884863A0 (fi) 1988-10-21
HUT48629A (en) 1989-06-28
US5175158A (en) 1992-12-29
IL88121A (en) 1993-06-10
DK586188A (da) 1989-04-24
AU609530B2 (en) 1991-05-02
HU199471B (en) 1990-02-28

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