DK586188A - Kondenserede diazepinoner, fremgangsmaade til deres fremstilling og laegemidler med indhold af saadanne forbindelser - Google Patents

Kondenserede diazepinoner, fremgangsmaade til deres fremstilling og laegemidler med indhold af saadanne forbindelser

Info

Publication number
DK586188A
DK586188A DK586188A DK586188A DK586188A DK 586188 A DK586188 A DK 586188A DK 586188 A DK586188 A DK 586188A DK 586188 A DK586188 A DK 586188A DK 586188 A DK586188 A DK 586188A
Authority
DK
Denmark
Prior art keywords
procedures
compounds
preparation
medicines containing
condensed diazepinones
Prior art date
Application number
DK586188A
Other languages
English (en)
Other versions
DK586188D0 (da
Inventor
Wolfgang Eberlein
Wolfhard Engel
Guenter Trummlitz
Gerhard Mihm
Norbert Mayer
Henri Doods
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK586188D0 publication Critical patent/DK586188D0/da
Publication of DK586188A publication Critical patent/DK586188A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK586188A 1987-10-23 1988-10-21 Kondenserede diazepinoner, fremgangsmaade til deres fremstilling og laegemidler med indhold af saadanne forbindelser DK586188A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873735895 DE3735895A1 (de) 1987-10-23 1987-10-23 Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
DK586188D0 DK586188D0 (da) 1988-10-21
DK586188A true DK586188A (da) 1989-04-24

Family

ID=6338927

Family Applications (1)

Application Number Title Priority Date Filing Date
DK586188A DK586188A (da) 1987-10-23 1988-10-21 Kondenserede diazepinoner, fremgangsmaade til deres fremstilling og laegemidler med indhold af saadanne forbindelser

Country Status (16)

Country Link
US (1) US5175158A (da)
EP (1) EP0312895A3 (da)
JP (1) JPH0660172B2 (da)
KR (1) KR890006646A (da)
AU (1) AU609530B2 (da)
CA (1) CA1321996C (da)
DD (1) DD283141A5 (da)
DE (1) DE3735895A1 (da)
DK (1) DK586188A (da)
FI (1) FI87073C (da)
HU (1) HU199471B (da)
IL (1) IL88121A (da)
NO (1) NO167146C (da)
NZ (1) NZ226681A (da)
PT (1) PT88808B (da)
ZA (1) ZA887877B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
US5366972A (en) * 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
ATE103918T1 (de) * 1989-06-28 1994-04-15 Boehringer Ingelheim Pharma 5,11-dihydro-6h-dipyrido(3,2-b:2',3'e>(1,4>diazepin-6-one und -thione und ihre verwendung bei der aids-vorbeugung oder behandlung.
CA2030056C (en) * 1989-11-17 1995-10-17 Karl D. Hargrave 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines and their use in the prevention or treatment of hiv infection
IE912239A1 (en) * 1990-07-24 1992-01-29 Akzo Nv Tetrahydropyridinyldibenzazepine derivatives
DE4112014A1 (de) * 1991-04-12 1992-10-15 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung
US5610155A (en) * 1992-04-09 1997-03-11 Dr. Karl Thomae Gmbh Condensed diazepinones, processes for preparing them and agents containing these compounds for treating diseases of the central nervous system and for promoting cerebral blood circulation
ES2180575T3 (es) * 1993-04-05 2003-02-16 Pharmaceutical Discovery Corp Pirido(2,3-b)(1,4)benzodiazepinonas como ligando de receptor m2 para el tratamiento de trastornos neurologicos.
US6316623B1 (en) * 1998-08-21 2001-11-13 Isis Pharmaceuticals, Inc. Ethylenediamine compound libraries
JPWO2004011430A1 (ja) * 2002-07-25 2005-11-24 アステラス製薬株式会社 ナトリウムチャネル阻害剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3235795A1 (de) * 1982-09-28 1984-03-29 Dr. Karl Thomae Gmbh, 7950 Biberach Neues verfahren zur herstellung von 5,11-dihydro-11-((4-methyl-1-piperazinyl)- acetyl)- 6h-pyrido(2,3-b)(1,4)- benzodiazepin-6-on
DE3409237A1 (de) * 1984-03-14 1985-09-19 Dr. Karl Thomae Gmbh, 7950 Biberach Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
NZ226681A (en) 1991-06-25
PT88808B (pt) 1993-01-29
US5175158A (en) 1992-12-29
IL88121A0 (en) 1989-06-30
HUT48629A (en) 1989-06-28
JPH0660172B2 (ja) 1994-08-10
EP0312895A2 (de) 1989-04-26
FI87073C (fi) 1992-11-25
FI884863A7 (fi) 1989-04-24
NO167146B (no) 1991-07-01
JPH01230580A (ja) 1989-09-14
HU199471B (en) 1990-02-28
NO884698D0 (no) 1988-10-21
CA1321996C (en) 1993-09-07
FI884863A0 (fi) 1988-10-21
DD283141A5 (de) 1990-10-03
DE3735895A1 (de) 1989-05-03
ZA887877B (en) 1990-06-27
FI87073B (fi) 1992-08-14
KR890006646A (ko) 1989-06-15
AU2412288A (en) 1989-04-27
EP0312895A3 (de) 1990-08-16
IL88121A (en) 1993-06-10
NO167146C (no) 1991-10-09
AU609530B2 (en) 1991-05-02
DK586188D0 (da) 1988-10-21
NO884698L (no) 1989-04-24

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Legal Events

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AHS Application shelved for other reasons than non-payment