DD269557A5 - Verfahren zur herstellung einer zusammensetzung zur wirksamen prephylaxe von brustkrebs bei frauen und zur empfaengnisverhuetung - Google Patents

Verfahren zur herstellung einer zusammensetzung zur wirksamen prephylaxe von brustkrebs bei frauen und zur empfaengnisverhuetung Download PDF

Info

Publication number
DD269557A5
DD269557A5 DD88313924A DD31392488A DD269557A5 DD 269557 A5 DD269557 A5 DD 269557A5 DD 88313924 A DD88313924 A DD 88313924A DD 31392488 A DD31392488 A DD 31392488A DD 269557 A5 DD269557 A5 DD 269557A5
Authority
DD
German Democratic Republic
Prior art keywords
melatonin
progestogen
estrogen
cycle
women
Prior art date
Application number
DD88313924A
Other languages
German (de)
English (en)
Inventor
Michael Cohen
Original Assignee
����������@������@�������k���Kk��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ����������@������@�������k���Kk�� filed Critical ����������@������@�������k���Kk��
Publication of DD269557A5 publication Critical patent/DD269557A5/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DD88313924A 1987-03-23 1988-03-23 Verfahren zur herstellung einer zusammensetzung zur wirksamen prephylaxe von brustkrebs bei frauen und zur empfaengnisverhuetung DD269557A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/029,229 US4855305A (en) 1987-03-23 1987-03-23 Compositions and methods of effecting contraception utilizing melatonin

Publications (1)

Publication Number Publication Date
DD269557A5 true DD269557A5 (de) 1989-07-05

Family

ID=21847942

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88313924A DD269557A5 (de) 1987-03-23 1988-03-23 Verfahren zur herstellung einer zusammensetzung zur wirksamen prephylaxe von brustkrebs bei frauen und zur empfaengnisverhuetung

Country Status (26)

Country Link
US (1) US4855305A (pt)
EP (1) EP0354921B1 (pt)
JP (2) JP2965160B2 (pt)
KR (1) KR890700349A (pt)
CN (1) CN1041383C (pt)
AT (1) ATE143807T1 (pt)
AU (3) AU628784B2 (pt)
BG (1) BG51075A1 (pt)
BR (1) BR8807426A (pt)
CA (1) CA1322527C (pt)
DD (1) DD269557A5 (pt)
DE (1) DE3855606T2 (pt)
EG (1) EG18583A (pt)
ES (1) ES2009251A6 (pt)
FI (1) FI894423A (pt)
GR (1) GR1002146B (pt)
HU (1) HU208487B (pt)
IL (1) IL85814A (pt)
IN (1) IN166946B (pt)
NZ (1) NZ223989A (pt)
OA (1) OA09134A (pt)
PH (1) PH26709A (pt)
PT (1) PT87053B (pt)
RU (1) RU2114621C1 (pt)
WO (1) WO1988007370A1 (pt)
ZA (1) ZA882079B (pt)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1001395B (el) * 1987-03-23 1993-10-29 Michael Cohen Συν?έσεις και μέ?οδοι προς πραγματοποίηση αντισύλληψης.
EP0300630A3 (en) * 1987-07-03 1990-03-28 Schering Agrochemicals Limited Melatonin for regulating animal reproduction
EP0305194A3 (en) * 1987-08-28 1990-03-28 Schering Agrochemicals Limited Veterinary composition
GR900100024A (el) * 1989-01-17 1991-06-07 Amr Int Μέθοδος θεραπείας του προεμμηνορροϊκού συνδρόμου.
US4945103A (en) * 1989-01-17 1990-07-31 Michael Cohen Method of treating pre-menstrual syndrome
IN170311B (pt) * 1989-01-17 1992-03-14 Cohen Michael
AU644367B2 (en) * 1989-05-17 1993-12-09 Applied Medical Research Ltd Use of melatonin derivatives for effecting contraception
NZ233697A (en) * 1989-05-17 1996-12-20 Applied Med Res Ltd Contraceptive composition comprising a melatonin analogue and a progestogen and/or an estrogen
IT1243193B (it) * 1990-08-10 1994-05-24 Medea Res Srl Composizioni farmaceutiche orali a base di melatonina
ATE190490T1 (de) * 1990-09-28 2000-04-15 I F L O S A S Di Giorgio E Ald Kontrazeptives und menstruationszyklus regulierendes präparat mit onkostatischen eigenschaften
ES2134789T3 (es) * 1991-05-09 1999-10-16 Neurim Pharma 1991 Composiciones que contienen melatonina.
AU660336B2 (en) * 1991-10-18 1995-06-22 Alza Corporation Device for the transdermal administration of melatonin
US5196435A (en) * 1991-11-21 1993-03-23 Eli Lilly And Company Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
IL105240A (en) * 1992-04-07 1999-04-11 Neurim Pharma 1991 The use of melatonin in the preparation of a drug for the treatment of benign prostatic hyperplasia
US6403631B1 (en) 1995-11-24 2002-06-11 Equitech Laboratories, Inc. Method and compositions for enhancing pregnancy success in an animal
US5792785A (en) * 1995-11-24 1998-08-11 Equitech Laboratories, Inc. Method for enhancing pregnancy success in an animal
US6028064A (en) * 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6620836B1 (en) * 1997-01-22 2003-09-16 Jay Patrick Antiarrhythmic and tranquilizer composition and treatment
DE19739916C2 (de) * 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
NZ504351A (en) 1997-11-14 2002-10-25 Akzo Nobel Nv Contraceptive kit comprising progestogen and anti-progestogen and use in treating bleeding induced by a progestogen-only contraceptive regimen
US6133453A (en) * 1998-05-15 2000-10-17 Pharm-Eco Laboratories, Inc. Method for making substituted indoles
US6660726B2 (en) 2000-03-10 2003-12-09 Endeavor Pharmaceuticals Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US7989436B2 (en) 2003-07-23 2011-08-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and pharmaceutical formulations comprising the same
US7459445B2 (en) * 2000-03-10 2008-12-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and topical pharmaceutical formulations of the same
US6855703B1 (en) 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US20050113351A1 (en) * 2000-03-21 2005-05-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20040176336A1 (en) * 2000-03-21 2004-09-09 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20030139384A1 (en) * 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
KR100861603B1 (ko) * 2000-08-30 2008-10-07 유니메드 파마슈티칼스, 엘엘씨 발기부전의 치료 및 남성의 리비도를 증가시키는 방법
AU2003230644A1 (en) * 2002-03-14 2003-09-29 Ercole L. Cavalieri A unifying mechanism and methods to prevent cancer and neurodegenerative diseases
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
CA2521471A1 (en) * 2003-04-11 2004-10-28 Barr Laboratories, Inc. Methods of administering estrogens and progestins
SI1663197T1 (sl) 2003-09-09 2008-06-30 Biogen Idec Internat Gmbh Uporaba derivatov fumarne kisline za zdravljenje sräśne insuficience in astme
MXPA06013418A (es) * 2004-05-26 2007-01-23 Wyeth Corp Composiciones y metodos para el tratamiento del trastorno disforico premenstrual.
PT2801355E (pt) 2004-10-08 2015-09-18 Forward Pharma As Composições farmacêuticas de libertação controlada compreendendo um éster de ácido fumárico
PL2450041T3 (pl) 2005-10-12 2019-02-28 Unimed Pharmaceuticals, Llc Ulepszony żel zawierający testosteron do zastosowania do leczenia hipogonadyzmu
WO2008032238A2 (en) * 2006-09-13 2008-03-20 Koninklijke Philips Electronics N. V. Device for automatic adjustment of the dose of melatonin and/or delivery of melatonin
ES2916604T1 (es) 2007-02-08 2022-07-04 Biogen Ma Inc Ensayos de detección de nrf2 y métodos y composiciones relacionados
DE102008036825A1 (de) * 2008-08-05 2010-02-11 Aicuris Gmbh & Co. Kg Schwangerschaftsvermeidung durch Gestagene
FR2937862B1 (fr) * 2008-11-03 2010-11-19 Mohammed Ridha Chakroun Kit contraceptif
US11344531B2 (en) * 2014-03-27 2022-05-31 Servicio Andaluz De Salud Durable preparation of an injectable of melatonin exhibiting long-term stability
RU2617518C2 (ru) * 2015-07-01 2017-04-25 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения и контрацепции самок млекопитающих
RU2616252C2 (ru) * 2015-08-04 2017-04-13 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения самцов млекопитающих

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087444A (en) * 1976-09-08 1978-05-02 Eli Lilly And Company Amides as ovulation inhibitors
DE2967049D1 (en) * 1978-04-11 1984-07-19 Efamol Ltd Pharmaceutical and dietary composition comprising gamma-linolenic acids
US4425339A (en) * 1981-04-09 1984-01-10 Syntex (U.S.A.) Inc. Treatment of menopausal symptoms
US4390531A (en) * 1981-08-10 1983-06-28 Syntex Pharmaceuticals International Ltd. Method of contraception using peak progestogen dosage
US4628051A (en) * 1983-09-26 1986-12-09 Ortho Pharmaceutical Corporation Triphasic oral contraceptive
US4614807A (en) * 1984-10-04 1986-09-30 Eli Lilly And Company 6,7-dihalomelatonins
US4746674A (en) * 1985-08-27 1988-05-24 Cellena (Cell Engineering) Ag Melatonin compositions and uses thereof
JPH0778007B2 (ja) * 1985-03-04 1995-08-23 セレ−ナ （セル・エンジニアリング） ア−・ゲ− メラトニン組成物とその使用
US4997845A (en) * 1987-02-02 1991-03-05 Eli Lilly And Company β-alkylmelatonins as ovulation inhibitors

Also Published As

Publication number Publication date
CA1322527C (en) 1993-09-28
ATE143807T1 (de) 1996-10-15
BR8807426A (pt) 1990-04-10
FI894423A0 (fi) 1989-09-19
AU8693891A (en) 1991-12-19
WO1988007370A1 (en) 1988-10-06
GR1002146B (en) 1996-02-19
EP0354921A1 (en) 1990-02-21
NZ223989A (en) 1991-08-27
IL85814A (en) 1992-05-25
US4855305A (en) 1989-08-08
AU676523B2 (en) 1997-03-13
ES2009251A6 (es) 1989-09-16
PH26709A (en) 1992-09-15
JP2965160B2 (ja) 1999-10-18
EP0354921A4 (en) 1991-08-07
JPH02502724A (ja) 1990-08-30
RU2114621C1 (ru) 1998-07-10
AU628784B2 (en) 1992-09-24
HU208487B (en) 1993-11-29
BG51075A1 (en) 1993-02-15
DE3855606D1 (de) 1996-11-14
GR880100177A (el) 1989-01-31
PT87053B (pt) 1993-09-30
EP0354921B1 (en) 1996-10-09
IN166946B (pt) 1990-08-11
KR890700349A (ko) 1989-04-24
IL85814A0 (en) 1990-02-09
PT87053A (pt) 1989-03-30
OA09134A (en) 1991-10-31
FI894423A (fi) 1989-09-19
AU1683088A (en) 1988-11-02
HUT52954A (en) 1990-09-28
ZA882079B (en) 1988-09-15
EG18583A (en) 1993-06-30
JPH1171276A (ja) 1999-03-16
CN1041383C (zh) 1998-12-30
CN88101379A (zh) 1988-10-05
DE3855606T2 (de) 1997-02-13
AU5513494A (en) 1994-04-14

Similar Documents

Publication Publication Date Title
DD269557A5 (de) Verfahren zur herstellung einer zusammensetzung zur wirksamen prephylaxe von brustkrebs bei frauen und zur empfaengnisverhuetung
DE60216630T2 (de) Verwendung von östrogen in kombination mit progestogen für die hormonsubstitutiionstherapie
DE19739916C2 (de) Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
DE60209907T2 (de) Verwendung von oestrogenverbindungen zur steigerung der libido bei frauen
DE69532894T2 (de) Verfahren zur empfängnisverhütung
EP2445491B1 (de) Pharmazeutische zusammensetzung zur notfallempfängnisverhütung
DE3750764T2 (de) Kontinuierliche verabreichung des luteinisierendes hormon abgebenden hormons in kombination mit sexsteroidverabreichung als empfängnisverhütungsmittel.
EP2552404B1 (de) Parenterale arzneiform, die aromatasehemmer und gestagene freisetzt, für die behandlung von endometriose
DE69804918T2 (de) Sehr niedrigdosiertes orales Kontrazeptiv mit weniger Menstruationsblutungen und verzögerter Wirkung
DE69222500T2 (de) Verfahren und formulierungen zur kontrazeption und zur behandlung von benignen gynäkologischen störungen
EP0723439B1 (de) Kombination von progesteronantagonisten und antiöstrogenen mit partialer agonistischer wirkung für die hormonsubstitutions-therapie für peri- und postmenopausale frauen
DE60130147T2 (de) Verwendung oraler formulierungen zur behandlung der weiblichen sexuellen störung
DE4429398C2 (de) Verwendung von Estra-1,3,5(10)-trien-Derivaten zur hormonalen Kontrazeption
DE69605899T2 (de) Gel zur lokalen hormontherapie der vaginalen trockenheit
DE60315939T2 (de) Pharmazeutische zusammensetzung enthaltend ein androgen
DE60203929T2 (de) Behandlungsverfahren und pharmazeutische zusammensetzung zur notfall-empfängnisverhütung
WO1996019997A1 (de) Progesteronantagonistisch- und antiöstrogen wirksame verbindungen zur gemeinsamen verwendung für die weibliche kontrazeption
DE60223795T2 (de) Tetrahydroxyliertes Östrogen enthaltendes Arzneistoffverabreichungssystem zur Verwendung in der hormonalen Kontrazeption
DE19705229A1 (de) Mittel zur hormonalen Kontrazeption
DE60115274T2 (de) Verwendung von antiprogestinen zur prophylaxe und behandlung von hormonabhängigen erkrankungen
DE69027028T2 (de) Als männliches kontrazeptikum verwendbare zusammensetzungen
DE602004009288T2 (de) Verwendung einer kombination eines aromatasehemmers, eines progestins und eines oestrogens zur behandlung von endometriose
DD238921A5 (de) Verfahren zur herstellung einer kontrazeptiven synergistischen zusammensetzung
DE69115294T2 (de) Zusammensetzungen und Verfahren zur Linderung der Symptome der Menopause.
DE69430732T2 (de) Kit zur verhütung oder hemmung der befruchtung

Legal Events

Date Code Title Description
A5 Published as prov. exclusive patent
ENJ Ceased due to non-payment of renewal fee