DD202146A5 - Verfahren zur herstellung von substituierten acylderivaten von octahydro-1h-indol-2-carbon-saeure-verbindungen - Google Patents

Verfahren zur herstellung von substituierten acylderivaten von octahydro-1h-indol-2-carbon-saeure-verbindungen Download PDF

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Publication number
DD202146A5
DD202146A5 DD81233892A DD23389281A DD202146A5 DD 202146 A5 DD202146 A5 DD 202146A5 DD 81233892 A DD81233892 A DD 81233892A DD 23389281 A DD23389281 A DD 23389281A DD 202146 A5 DD202146 A5 DD 202146A5
Authority
DD
German Democratic Republic
Prior art keywords
octahydro
indole
formula
group
carboxylic acid
Prior art date
Application number
DD81233892A
Other languages
German (de)
English (en)
Inventor
Milton L Hoefle
George Bobowski
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DD202146A5 publication Critical patent/DD202146A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DD81233892A 1980-10-06 1981-10-05 Verfahren zur herstellung von substituierten acylderivaten von octahydro-1h-indol-2-carbon-saeure-verbindungen DD202146A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19430780A 1980-10-06 1980-10-06
US06/233,940 US4350704A (en) 1980-10-06 1981-02-17 Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids

Publications (1)

Publication Number Publication Date
DD202146A5 true DD202146A5 (de) 1983-08-31

Family

ID=26889887

Family Applications (2)

Application Number Title Priority Date Filing Date
DD81233892A DD202146A5 (de) 1980-10-06 1981-10-05 Verfahren zur herstellung von substituierten acylderivaten von octahydro-1h-indol-2-carbon-saeure-verbindungen
DD81233893A DD201782A5 (de) 1980-10-06 1981-10-05 Verfahren zur herstellung von octahydro-1-(omega-mercaptoalkanoyl)-1h-indol 2-carbonsaeure-verbindungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD81233893A DD201782A5 (de) 1980-10-06 1981-10-05 Verfahren zur herstellung von octahydro-1-(omega-mercaptoalkanoyl)-1h-indol 2-carbonsaeure-verbindungen

Country Status (5)

Country Link
US (1) US4350704A (fr)
EP (2) EP0088341B1 (fr)
DD (2) DD202146A5 (fr)
GR (1) GR75355B (fr)
PH (1) PH20330A (fr)

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Also Published As

Publication number Publication date
DD201782A5 (de) 1983-08-10
EP0088341B1 (fr) 1987-07-22
GR75355B (fr) 1984-07-13
EP0088341A1 (fr) 1983-09-14
PH20330A (en) 1986-12-02
EP0088342A1 (fr) 1983-09-14
US4350704A (en) 1982-09-21

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