DD148215A5 - Verfahren zur herstellung von bicyclo eckige klammer auf 3.1.0 eckige klammer zu hexyl-substituierten carbonylaminophenoxyverbindungen - Google Patents

Verfahren zur herstellung von bicyclo eckige klammer auf 3.1.0 eckige klammer zu hexyl-substituierten carbonylaminophenoxyverbindungen Download PDF

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Publication number
DD148215A5
DD148215A5 DD79214074A DD21407479A DD148215A5 DD 148215 A5 DD148215 A5 DD 148215A5 DD 79214074 A DD79214074 A DD 79214074A DD 21407479 A DD21407479 A DD 21407479A DD 148215 A5 DD148215 A5 DD 148215A5
Authority
DD
German Democratic Republic
Prior art keywords
compounds
formula
endobicyclo
phenoxy
compound
Prior art date
Application number
DD79214074A
Other languages
German (de)
English (en)
Inventor
Karl G Untch
Belig M Berkoz
Stefan H Unger
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DD148215A5 publication Critical patent/DD148215A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/132—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings
    • C07C53/136—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DD79214074A 1978-07-03 1979-07-03 Verfahren zur herstellung von bicyclo eckige klammer auf 3.1.0 eckige klammer zu hexyl-substituierten carbonylaminophenoxyverbindungen DD148215A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/921,371 US4177280A (en) 1978-07-03 1978-07-03 Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents

Publications (1)

Publication Number Publication Date
DD148215A5 true DD148215A5 (de) 1981-05-13

Family

ID=25445332

Family Applications (1)

Application Number Title Priority Date Filing Date
DD79214074A DD148215A5 (de) 1978-07-03 1979-07-03 Verfahren zur herstellung von bicyclo eckige klammer auf 3.1.0 eckige klammer zu hexyl-substituierten carbonylaminophenoxyverbindungen

Country Status (13)

Country Link
US (1) US4177280A (fr)
EP (1) EP0007710A1 (fr)
JP (1) JPS559074A (fr)
AU (1) AU4852379A (fr)
CA (1) CA1105054A (fr)
DD (1) DD148215A5 (fr)
DK (1) DK276479A (fr)
ES (1) ES482075A1 (fr)
IL (1) IL57705A0 (fr)
NZ (1) NZ190880A (fr)
PL (1) PL116994B1 (fr)
SU (1) SU854271A3 (fr)
ZA (1) ZA793292B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4402976A (en) * 1981-04-24 1983-09-06 E. R. Squibb & Sons, Inc. Method for treating glaucoma with systemic nadolol compositions
DE3887544T2 (de) * 1987-03-09 1994-06-01 Procter & Gamble Beta-aminoethyl-substituierte Phenyl-Verbindungen, diese enthaltende entzündungshemmende oder analgetische Zusammensetzungen.
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
EP1889198B1 (fr) 2005-04-28 2014-11-26 Proteus Digital Health, Inc. Systeme pharma-informatique
WO2008036682A2 (fr) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Traitement des troubles hépatiques par l'administration de conjugués de protéine associée au récepteur (rap)
DK3395372T3 (da) 2009-02-20 2022-04-19 Enhanx Biopharm Inc System til afgivelse af glutathion-baseret medikament
EP2427178B1 (fr) 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Compositions pour libération dermique comprenant des complexes principe actif-particule de phosphate de calcium et procédés d'utilisation associés
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US11173145B2 (en) 2017-01-17 2021-11-16 Board Of Regents, The University Of Texas System Compounds useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase
WO2020018670A1 (fr) 2018-07-17 2020-01-23 Board Of Regents, The University Of Texas System Composés utiles en tant qu'inhibiteurs de l'indoléamine 2,3-dioxygénase et/ou de la tryptophane dioxygénase

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1078852A (en) * 1964-09-30 1967-08-09 Ici Ltd Alkanolamine derivatives
CA1149819A (fr) * 1970-01-08 1983-07-12 Max Wilhelm Procede de fabrication de nouvelles amines
US4038313A (en) * 1970-01-08 1977-07-26 Ciba-Geigy Corporation Cycloalkylureido phenoxy propanolamines
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
US4035420A (en) * 1972-07-06 1977-07-12 Aktiebolaget Hassle Substituted ureido alkylene phenoxy propanolamines
AT334385B (de) * 1973-12-20 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen
US4063025A (en) * 1975-02-05 1977-12-13 Yamanouchi Pharmaceutical Co., Ltd. 4-Substituted amino-α-aminomethylbenzyl alcohol derivatives
US4064258A (en) * 1976-07-19 1977-12-20 Syntex (U.S.A.) Inc. Thiazole cardiovascular agents

Also Published As

Publication number Publication date
US4177280A (en) 1979-12-04
DK276479A (da) 1980-01-04
SU854271A3 (ru) 1981-08-07
JPS559074A (en) 1980-01-22
PL116994B1 (en) 1981-07-31
PL216661A1 (fr) 1980-03-24
AU4852379A (en) 1980-01-10
ZA793292B (en) 1981-02-25
ES482075A1 (es) 1980-03-01
CA1105054A (fr) 1981-07-14
IL57705A0 (en) 1979-11-30
NZ190880A (en) 1981-04-24
EP0007710A1 (fr) 1980-02-06

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