DD133943A5 - Verfahren zur herstellung von optisch aktiven azabicycloalkanen - Google Patents
Verfahren zur herstellung von optisch aktiven azabicycloalkanenInfo
- Publication number
- DD133943A5 DD133943A5 DD77201039A DD20103977A DD133943A5 DD 133943 A5 DD133943 A5 DD 133943A5 DD 77201039 A DD77201039 A DD 77201039A DD 20103977 A DD20103977 A DD 20103977A DD 133943 A5 DD133943 A5 DD 133943A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- azabicycloalkanes
- optically active
- preparing optically
- preparing
- active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/40—Unsaturated compounds containing halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/36—Polyhydroxylic alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/28—Unsaturated compounds polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/34—Unsaturated compounds containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72340276A | 1976-09-15 | 1976-09-15 | |
| US05/809,339 US4131611A (en) | 1975-07-31 | 1977-06-23 | Azabicyclohexanes |
| US05/809,340 US4118417A (en) | 1977-06-23 | 1977-06-23 | Process for resolving cis-1-substituted phenyl-1,2-cyclopropanedicarboxylic acids |
| US05/809,341 US4118393A (en) | 1977-06-23 | 1977-06-23 | Phenyl azabicyclohexanones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD133943A5 true DD133943A5 (de) | 1979-01-31 |
Family
ID=27505564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD77201039A DD133943A5 (de) | 1976-09-15 | 1977-09-15 | Verfahren zur herstellung von optisch aktiven azabicycloalkanen |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5337656A (ko) |
| AR (2) | AR220684A1 (ko) |
| AT (2) | AT367036B (ko) |
| AU (1) | AU519620B2 (ko) |
| BE (1) | BE858683A (ko) |
| CH (2) | CH637929A5 (ko) |
| DD (1) | DD133943A5 (ko) |
| DE (1) | DE2740562A1 (ko) |
| DK (3) | DK146245C (ko) |
| FR (1) | FR2375212A1 (ko) |
| GR (1) | GR72713B (ko) |
| HU (1) | HU177531B (ko) |
| NL (1) | NL189041C (ko) |
| PL (1) | PL115869B1 (ko) |
| SE (2) | SE435384B (ko) |
| YU (2) | YU39499B (ko) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0007128A1 (en) * | 1978-07-06 | 1980-01-23 | Shell Internationale Researchmaatschappij B.V. | Derivatives of 3-azabicyclo(3.1.0)hexane and processes for their preparation |
| EP0007652A1 (en) * | 1978-06-27 | 1980-02-06 | Shell Internationale Researchmaatschappij B.V. | Derivatives of 3-azabicyclo(3.1.0)hexane and a process for their preparation |
| EP0008813A1 (en) * | 1978-07-06 | 1980-03-19 | Shell Internationale Researchmaatschappij B.V. | Processes for the preparation of 3-azabicyclo(3.1.0)hexane derivatives |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL65843A (en) * | 1977-08-11 | 1986-12-31 | American Cyanamid Co | Pharmaceutical compositions for the treatment of depression containing 3-aza-bicyclo(3.1.0)hexane derivatives and certain novel compounds of this type |
| JPS6332100A (ja) * | 1986-07-25 | 1988-02-10 | 東京電力株式会社 | シ−ルド掘進機 |
| JPH0658037B2 (ja) * | 1989-09-01 | 1994-08-03 | 日本鋼管株式会社 | シールド掘進装置 |
| US6372919B1 (en) | 2001-01-11 | 2002-04-16 | Dov Pharmaceutical, Inc. | (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as an anti-depressant agent |
| US6569887B2 (en) | 2001-08-24 | 2003-05-27 | Dov Pharmaceuticals Inc. | (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake |
| US20080081834A1 (en) | 2002-07-31 | 2008-04-03 | Lippa Arnold S | Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders |
| BRPI0512186A (pt) * | 2004-07-22 | 2008-02-19 | Wyeth Corp | método para o tratamento de desordens e condições do sistema nervoso |
| AU2005266997A1 (en) * | 2004-07-22 | 2006-02-02 | Wyeth | Method for treating nervous system disorders and conditions |
| US20070043100A1 (en) | 2005-08-16 | 2007-02-22 | Hagen Eric J | Novel polymorphs of azabicyclohexane |
| CA2659215C (en) * | 2005-07-27 | 2018-07-10 | Dov Pharmaceutical, Inc. | Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders |
| US20080045725A1 (en) | 2006-04-28 | 2008-02-21 | Murry Jerry A | Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane |
| US8138377B2 (en) | 2006-11-07 | 2012-03-20 | Dov Pharmaceutical, Inc. | Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use |
| US9133159B2 (en) | 2007-06-06 | 2015-09-15 | Neurovance, Inc. | 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1351754A (en) * | 1970-07-02 | 1974-05-01 | Allen & Hanburys Ltd | Indenopyrrole derivatives |
-
1977
- 1977-08-16 GR GR54169A patent/GR72713B/el unknown
- 1977-08-26 AR AR268968A patent/AR220684A1/es active
- 1977-09-01 AU AU28441/77A patent/AU519620B2/en not_active Ceased
- 1977-09-02 NL NLAANVRAGE7709691,A patent/NL189041C/xx not_active IP Right Cessation
- 1977-09-08 DE DE19772740562 patent/DE2740562A1/de active Granted
- 1977-09-13 CH CH1118977A patent/CH637929A5/de not_active IP Right Cessation
- 1977-09-13 YU YU2174/77A patent/YU39499B/xx unknown
- 1977-09-14 FR FR7727755A patent/FR2375212A1/fr active Granted
- 1977-09-14 PL PL1977200831A patent/PL115869B1/pl unknown
- 1977-09-14 HU HU77AE508A patent/HU177531B/hu unknown
- 1977-09-14 BE BE180894A patent/BE858683A/xx not_active IP Right Cessation
- 1977-09-14 AT AT0661577A patent/AT367036B/de not_active IP Right Cessation
- 1977-09-14 DK DK407577A patent/DK146245C/da not_active IP Right Cessation
- 1977-09-15 SE SE7710367A patent/SE435384B/xx not_active IP Right Cessation
- 1977-09-15 DD DD77201039A patent/DD133943A5/xx unknown
- 1977-09-16 JP JP11064777A patent/JPS5337656A/ja active Granted
-
1978
- 1978-09-19 AR AR273764A patent/AR227507A1/es active
-
1980
- 1980-05-30 AT AT0288280A patent/AT367037B/de not_active IP Right Cessation
- 1980-10-16 DK DK438580A patent/DK438580A/da not_active Application Discontinuation
- 1980-10-16 DK DK438480A patent/DK438480A/da not_active Application Discontinuation
-
1982
- 1982-04-05 CH CH209382A patent/CH637931A5/de not_active IP Right Cessation
- 1982-06-03 SE SE8203437A patent/SE452610B/sv not_active IP Right Cessation
- 1982-08-23 YU YU1885/82A patent/YU43523B/xx unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0007652A1 (en) * | 1978-06-27 | 1980-02-06 | Shell Internationale Researchmaatschappij B.V. | Derivatives of 3-azabicyclo(3.1.0)hexane and a process for their preparation |
| EP0007128A1 (en) * | 1978-07-06 | 1980-01-23 | Shell Internationale Researchmaatschappij B.V. | Derivatives of 3-azabicyclo(3.1.0)hexane and processes for their preparation |
| EP0008813A1 (en) * | 1978-07-06 | 1980-03-19 | Shell Internationale Researchmaatschappij B.V. | Processes for the preparation of 3-azabicyclo(3.1.0)hexane derivatives |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DD132488A5 (de) | Verfahren zur herstellung von reinem methyl-tertiaer-butylaether | |
| DD129103A5 (de) | Verfahren zur herstellung von n-phosphonomethylglycin | |
| DD135380A5 (de) | Verfahren zur herstellung von 4-acylamino-phenyl-aethanolaminen | |
| DD131931A5 (de) | Verfahren zur herstellung von spiro-hydantoin-verbindungen | |
| DD135500A5 (de) | Verfahren zur herstellung von polyaetheramid-saeuren | |
| DD133943A5 (de) | Verfahren zur herstellung von optisch aktiven azabicycloalkanen | |
| DD135482A5 (de) | Verfahren zur herstellung von p-benzochinon | |
| DD131858A5 (de) | Verfahren zur herstellung von 3-chlorcephemverbindungen | |
| AT348995B (de) | Verfahren zur herstellung von acylcyaniden | |
| DD130036A5 (de) | Verfahren zur herstellung von optisch aktiven 11-desoxy-16-aryloxy-omega-tetranorprostaglandinen | |
| DD128659A5 (de) | Verfahren zur herstellung von 4-androsten-3-onen | |
| DD138651A5 (de) | Verfahren zur herstellung von alpha-fluormethyl-alpha-amino-alkansaeuren | |
| AT347926B (de) | Verfahren zur herstellung von acylcyaniden | |
| DD129443A5 (de) | Verfahren zur herstellung von indazolyl-(4)-oxypropanolaminen | |
| DD131556A5 (de) | Verfahren zur herstellung von 5-m-tolyoxyuracil | |
| DD134089A5 (de) | Verfahren zur herstellung von 4-diphenylmethylen-1-hydroxybenzylpiperidinen | |
| AT348509B (de) | Verfahren zur herstellung von acylcyaniden | |
| DD132431A5 (de) | Verfahren zur herstellung von aryloxy-1-amino-3-propanolen-2 | |
| DD137228A5 (de) | Verfahren zur herstellung von 4-(1-hydroxy-1-methylaethyl)-3-cyclohexen-1-on-ketalen | |
| DD128591A5 (de) | Verfahren zur herstellung von 2-oxo-1-pyrrolidinen | |
| ATA312477A (de) | Verfahren zur herstellung von cholecystokinin- -pancreozymin-octapeptidamid-sulfatester | |
| DD131088A5 (de) | Verfahren zur herstellung von diaminoalkoxybenzolen | |
| DD130416A4 (de) | Verfahren zur herstellung von o-nitrobenzylbromid | |
| DD135908A5 (de) | Verfahren zur herstellung von halogenarylmalonamidooxacephalosporinen | |
| AT345786B (de) | Verfahren zur herstellung von o-dialkylaminomethylphenolen |