DD123322A5 - - Google Patents

Info

Publication number
DD123322A5
DD123322A5 DD188797A DD18879775A DD123322A5 DD 123322 A5 DD123322 A5 DD 123322A5 DD 188797 A DD188797 A DD 188797A DD 18879775 A DD18879775 A DD 18879775A DD 123322 A5 DD123322 A5 DD 123322A5
Authority
DD
German Democratic Republic
Application number
DD188797A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of DD123322A5 publication Critical patent/DD123322A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD188797A 1974-10-11 1975-10-10 DD123322A5 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1369774A CH602612A5 (cs) 1974-10-11 1974-10-11

Publications (1)

Publication Number Publication Date
DD123322A5 true DD123322A5 (cs) 1976-12-12

Family

ID=4394567

Family Applications (1)

Application Number Title Priority Date Filing Date
DD188797A DD123322A5 (cs) 1974-10-11 1975-10-10

Country Status (26)

Country Link
US (1) US4028402A (cs)
JP (1) JPS51125718A (cs)
AR (1) AR209457A1 (cs)
AT (1) AT343676B (cs)
BE (1) BE834369A (cs)
BR (1) BR7506595A (cs)
CA (1) CA1053258A (cs)
CH (1) CH602612A5 (cs)
CU (1) CU34371A (cs)
DD (1) DD123322A5 (cs)
DE (1) DE2542598A1 (cs)
DK (1) DK140834B (cs)
ES (1) ES441673A1 (cs)
FI (1) FI752626A7 (cs)
FR (1) FR2287221A1 (cs)
GB (1) GB1473256A (cs)
IE (1) IE41807B1 (cs)
IL (1) IL48116A (cs)
LU (1) LU73557A1 (cs)
NL (1) NL7511890A (cs)
NO (1) NO753447L (cs)
PH (1) PH12279A (cs)
PL (1) PL95259B1 (cs)
SE (1) SE7511357L (cs)
SU (1) SU572200A3 (cs)
ZA (1) ZA755861B (cs)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2401898A1 (fr) * 1977-09-05 1979-03-30 Aec Chim Organ Biolog Nouveau sel de l'acide patoique
US20020006899A1 (en) * 1998-10-06 2002-01-17 Pospisilik Andrew J. Use of dipeptidyl peptidase IV effectors for lowering blood pressure in mammals
DE122010000020I1 (de) 1996-04-25 2010-07-08 Prosidion Ltd Verfahren zur Senkung des Blutglukosespiegels in Säugern
US6399658B1 (en) 1996-12-24 2002-06-04 Sumitomo Pharmaceuticals Co., Ltd. Composition containing ascorbic acid
DE19823831A1 (de) * 1998-05-28 1999-12-02 Probiodrug Ges Fuer Arzneim Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen
DE19828114A1 (de) 1998-06-24 2000-01-27 Probiodrug Ges Fuer Arzneim Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
DE19828113A1 (de) 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
DE19834591A1 (de) 1998-07-31 2000-02-03 Probiodrug Ges Fuer Arzneim Verfahren zur Steigerung des Blutglukosespiegels in Säugern
US20030176357A1 (en) * 1998-10-06 2003-09-18 Pospisilik Andrew J. Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels
DE19926233C1 (de) 1999-06-10 2000-10-19 Probiodrug Ges Fuer Arzneim Verfahren zur Herstellung von Thiazolidin
DE19940130A1 (de) * 1999-08-24 2001-03-01 Probiodrug Ges Fuer Arzneim Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
CA2386379C (en) 1999-10-06 2009-12-15 Toshio Miyata Carbonyl stress-decreasing agent
US20080076811A1 (en) * 2000-01-21 2008-03-27 Bork Balkan Combinations comprising depeptidypeptidase-iv inhibitors and antidiabetic agents
BR0109553A (pt) * 2000-03-31 2003-06-03 Probiodrug Ag Método para o melhoramento de sinalização de ilhota em diabetes melito e para sua prevenção
FR2809310B1 (fr) 2000-05-26 2004-02-13 Centre Nat Rech Scient Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant
JP2005097117A (ja) * 2000-06-30 2005-04-14 Chugai Pharmaceut Co Ltd 糖尿病治療剤
DE60134563D1 (de) * 2000-10-27 2008-08-07 Probiodrug Ag Behandlung von neurologischen und neuropsychologischen störungen
US7132104B1 (en) 2000-10-27 2006-11-07 Probiodrug Ag Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders
US6890905B2 (en) 2001-04-02 2005-05-10 Prosidion Limited Methods for improving islet signaling in diabetes mellitus and for its prevention
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
DE10150203A1 (de) 2001-10-12 2003-04-17 Probiodrug Ag Peptidylketone als Inhibitoren der DPIV
US20030130199A1 (en) * 2001-06-27 2003-07-10 Von Hoersten Stephan Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
JP2005504766A (ja) * 2001-08-16 2005-02-17 プロバイオドラッグ アーゲー プロリンエンドペプチダーゼ阻害剤の、細胞内シグナルカスケード依存性イノシトール（１，４，５）トリホスフェート濃度調節への使用。
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
CN1622941A (zh) 2002-02-28 2005-06-01 普罗西迪恩有限公司 基于谷氨酰胺酰基的dpiv抑制剂
US20030232761A1 (en) * 2002-03-28 2003-12-18 Hinke Simon A. Novel analogues of glucose-dependent insulinotropic polypeptide
US20040033051A1 (en) * 2002-08-16 2004-02-19 Ip Kiril Kun Wan Method and system for producing and displaying visual presentations which inhibit off-screen duplication
US20040058876A1 (en) * 2002-09-18 2004-03-25 Torsten Hoffmann Secondary binding site of dipeptidyl peptidase IV (DP IV)
AU2003293311A1 (en) * 2002-09-18 2004-04-23 Prosidion Ltd. Secondary binding site of dipeptidyl peptidase iv (dp iv)
DE602004026289D1 (de) 2003-05-05 2010-05-12 Probiodrug Ag Glutaminylcyclase-hemmer
NZ572274A (en) 2003-05-05 2009-06-26 Probiodrug Ag Use of effectors of glutaminyl and glutamate cyclases
MXPA06003998A (es) * 2003-10-15 2006-06-27 Probiodrug Ag Uso de efectores de ciclasas de glutamato y glutaminil.
US20100099721A1 (en) * 2003-11-03 2010-04-22 Probiodrug Ag Novel compounds for the treatment of neurological disorders
US20050171112A1 (en) * 2003-11-03 2005-08-04 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
BRPI0507485A (pt) 2004-02-05 2007-07-10 Probiodrug Ag inibidores novos de glutaminil ciclase
KR100926417B1 (ko) 2007-01-29 2009-11-12 한올제약주식회사 Ｎ,ｎ―디메틸 이미도디카르본이미딕 디아미드의 초산염,그의 제조방법 및 그를 포함하는 약제학적 조성물
US20080188457A1 (en) * 2007-02-02 2008-08-07 Braincells, Inc. Modulation of Neurogenesis with Biguanides and GSK3-beta Agents
EP2203418B1 (en) * 2007-09-21 2017-10-25 HanAll Biopharma Co., Ltd. N,n-dimethyl imidodicarbonimidic diamide dicarboxylate, method for producing the same and pharmaceutical compositions comprising the same
WO2009088220A2 (ko) * 2008-01-08 2009-07-16 Hanall Pharmaceutical Company. Ltd Ｎ,ｎ-디메틸 이미도디카르본이미딕 디아미드의 니코틴산염, 그의 제조방법 및 그를 포함하는 약제학적 조성물
DK2303838T3 (en) * 2008-06-26 2014-03-03 Silanes Sa De Cv Lab New metforminglycinatsalt for blood glucose control
US20110021634A1 (en) 2009-06-18 2011-01-27 Patel Pranav Dushyant Processes for preparing metformin hydrochloride
WO2011049400A2 (ko) * 2009-10-23 2011-04-28 한올바이오파마주식회사 N,n-디메틸 이미도디카르본이미딕 디아미드의 산 부가염을 포함하는 항암용 약제학적 조성물
KR101324283B1 (ko) 2010-04-27 2013-11-01 한올바이오파마주식회사 바이구아나이드 화합물의 신규 염, 그의 제조방법, 그를 포함하는 약제학적 조성물
US11185516B2 (en) 2016-09-30 2021-11-30 Laboratorios Silanes S.A. De C.V. Metformin glycinate, pharmaceutical compositions comprising the same, and methods of using the same
WO2018060962A2 (en) 2016-09-30 2018-04-05 Laboratorios Silanes S.A. De C.V. Metformin amino acid compounds and methods of using the same
CN106986791A (zh) * 2017-05-11 2017-07-28 杜剑平 一种治疗肿瘤的药物化合物及其制备方法和应用
CN107118130A (zh) * 2017-05-11 2017-09-01 杜剑平 一类治疗肿瘤的药物化合物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3179562A (en) * 1961-08-23 1965-04-20 Du Pont Treatment of diabetes with alpha, alpha substituted acetic acid derivatives

Also Published As

Publication number Publication date
ES441673A1 (es) 1977-04-01
DK140834C (cs) 1980-04-28
BE834369A (fr) 1976-04-12
CU34371A (es) 1979-06-01
SE7511357L (sv) 1976-04-12
AT343676B (de) 1978-06-12
FR2287221A1 (fr) 1976-05-07
AR209457A1 (es) 1977-04-29
IL48116A0 (en) 1975-11-25
NO753447L (cs) 1976-04-13
JPS51125718A (en) 1976-11-02
PL95259B1 (pl) 1977-10-31
BR7506595A (pt) 1976-08-17
DE2542598A1 (de) 1976-04-22
CA1053258A (en) 1979-04-24
NL7511890A (nl) 1976-04-13
ATA776375A (de) 1977-10-15
CH602612A5 (cs) 1978-07-31
IL48116A (en) 1979-07-25
ZA755861B (en) 1976-08-25
PH12279A (en) 1978-12-12
SU572200A3 (ru) 1977-09-05
DK457475A (cs) 1976-04-12
AU8497775A (en) 1977-03-24
FI752626A7 (cs) 1976-04-12
IE41807L (en) 1976-04-11
LU73557A1 (cs) 1977-05-24
DK140834B (da) 1979-11-26
US4028402A (en) 1977-06-07
IE41807B1 (en) 1980-03-26
GB1473256A (en) 1977-05-11

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