CU34371A - Nuevas sales de biguanida y su procedimiento de obsales de biguanida y su procedimiento de obtenciontenci on - Google Patents

Nuevas sales de biguanida y su procedimiento de obsales de biguanida y su procedimiento de obtenciontenci on

Info

Publication number
CU34371A
CU34371A CU7534371A CU34371A CU34371A CU 34371 A CU34371 A CU 34371A CU 7534371 A CU7534371 A CU 7534371A CU 34371 A CU34371 A CU 34371A CU 34371 A CU34371 A CU 34371A
Authority
CU
Cuba
Prior art keywords
biguanida
procedure
obsals
salts
new
Prior art date
Application number
CU7534371A
Other languages
English (en)
Inventor
Ulf Ulffischer
Eckehard Lorch
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CU34371A publication Critical patent/CU34371A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CU7534371A 1974-10-11 1975-10-08 Nuevas sales de biguanida y su procedimiento de obsales de biguanida y su procedimiento de obtenciontenci on CU34371A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1369774A CH602612A5 (es) 1974-10-11 1974-10-11

Publications (1)

Publication Number Publication Date
CU34371A true CU34371A (es) 1979-06-01

Family

ID=4394567

Family Applications (1)

Application Number Title Priority Date Filing Date
CU7534371A CU34371A (es) 1974-10-11 1975-10-08 Nuevas sales de biguanida y su procedimiento de obsales de biguanida y su procedimiento de obtenciontenci on

Country Status (26)

Country Link
US (1) US4028402A (es)
JP (1) JPS51125718A (es)
AR (1) AR209457A1 (es)
AT (1) AT343676B (es)
BE (1) BE834369A (es)
BR (1) BR7506595A (es)
CA (1) CA1053258A (es)
CH (1) CH602612A5 (es)
CU (1) CU34371A (es)
DD (1) DD123322A5 (es)
DE (1) DE2542598A1 (es)
DK (1) DK140834B (es)
ES (1) ES441673A1 (es)
FI (1) FI752626A (es)
FR (1) FR2287221A1 (es)
GB (1) GB1473256A (es)
IE (1) IE41807B1 (es)
IL (1) IL48116A (es)
LU (1) LU73557A1 (es)
NL (1) NL7511890A (es)
NO (1) NO753447L (es)
PH (1) PH12279A (es)
PL (1) PL95259B1 (es)
SE (1) SE7511357L (es)
SU (1) SU572200A3 (es)
ZA (1) ZA755861B (es)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2401898A1 (fr) * 1977-09-05 1979-03-30 Aec Chim Organ Biolog Nouveau sel de l'acide patoique
US20020006899A1 (en) * 1998-10-06 2002-01-17 Pospisilik Andrew J. Use of dipeptidyl peptidase IV effectors for lowering blood pressure in mammals
DE19616486C5 (de) 1996-04-25 2016-06-30 Royalty Pharma Collection Trust Verfahren zur Senkung des Blutglukosespiegels in Säugern
US6399658B1 (en) 1996-12-24 2002-06-04 Sumitomo Pharmaceuticals Co., Ltd. Composition containing ascorbic acid
DE19823831A1 (de) * 1998-05-28 1999-12-02 Probiodrug Ges Fuer Arzneim Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen
DE19828113A1 (de) 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
DE19828114A1 (de) 1998-06-24 2000-01-27 Probiodrug Ges Fuer Arzneim Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
DE19834591A1 (de) 1998-07-31 2000-02-03 Probiodrug Ges Fuer Arzneim Verfahren zur Steigerung des Blutglukosespiegels in Säugern
US20030176357A1 (en) * 1998-10-06 2003-09-18 Pospisilik Andrew J. Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels
DE19926233C1 (de) 1999-06-10 2000-10-19 Probiodrug Ges Fuer Arzneim Verfahren zur Herstellung von Thiazolidin
DE19940130A1 (de) * 1999-08-24 2001-03-01 Probiodrug Ges Fuer Arzneim Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
JP4719393B2 (ja) 1999-10-06 2011-07-06 敏男 宮田 カルボニルストレス改善剤
US20080076811A1 (en) * 2000-01-21 2008-03-27 Bork Balkan Combinations comprising depeptidypeptidase-iv inhibitors and antidiabetic agents
EP2055302B1 (en) * 2000-03-31 2014-09-10 Royalty Pharma Collection Trust Method for the improvement of islet signaling in diabetes mellitus and for its prevention
FR2809310B1 (fr) 2000-05-26 2004-02-13 Centre Nat Rech Scient Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant
JP2005097117A (ja) * 2000-06-30 2005-04-14 Chugai Pharmaceut Co Ltd 糖尿病治療剤
CN1278683C (zh) * 2000-10-27 2006-10-11 前体生物药物股份有限公司 二肽基肽酶iv抑制剂在制备治疗焦虑症的药物中的用途
US7132104B1 (en) 2000-10-27 2006-11-07 Probiodrug Ag Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders
US6890905B2 (en) 2001-04-02 2005-05-10 Prosidion Limited Methods for improving islet signaling in diabetes mellitus and for its prevention
US20030130199A1 (en) 2001-06-27 2003-07-10 Von Hoersten Stephan Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
DE10150203A1 (de) 2001-10-12 2003-04-17 Probiodrug Ag Peptidylketone als Inhibitoren der DPIV
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
JP2005504766A (ja) * 2001-08-16 2005-02-17 プロバイオドラッグ アーゲー プロリンエンドペプチダーゼ阻害剤の、細胞内シグナルカスケード依存性イノシトール（１，４，５）トリホスフェート濃度調節への使用。
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
DE60217186T2 (de) 2002-02-28 2007-09-27 Prosidion Ltd. Dpiv-inhibitoren auf glutaminbasis
US20030232761A1 (en) * 2002-03-28 2003-12-18 Hinke Simon A. Novel analogues of glucose-dependent insulinotropic polypeptide
US20040033051A1 (en) * 2002-08-16 2004-02-19 Ip Kiril Kun Wan Method and system for producing and displaying visual presentations which inhibit off-screen duplication
EP1543023B1 (en) * 2002-09-18 2010-03-17 Prosidion Limited Secondary binding site of dipeptidyl peptidase iv (dp iv)
US20040058876A1 (en) * 2002-09-18 2004-03-25 Torsten Hoffmann Secondary binding site of dipeptidyl peptidase IV (DP IV)
KR20110059664A (ko) 2003-05-05 2011-06-02 프로비오드룩 아게 글루타미닐 및 글루타메이트 사이클라제의 이펙터의 용도
ATE462432T1 (de) 2003-05-05 2010-04-15 Probiodrug Ag Glutaminylcyclase-hemmer
EP2289498A1 (en) * 2003-10-15 2011-03-02 Probiodrug AG Use of inhibitors of glutaminyl clyclase
US20050171112A1 (en) * 2003-11-03 2005-08-04 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
US20100099721A1 (en) * 2003-11-03 2010-04-22 Probiodrug Ag Novel compounds for the treatment of neurological disorders
US7304086B2 (en) 2004-02-05 2007-12-04 Probiodrug Ag Inhibitors of glutaminyl cyclase
US8058312B2 (en) * 2007-01-29 2011-11-15 Hanall Biopharma Co., Ltd. N, N-dimethyl imidodicarbonimidic diamide acetate, method for producing the same and pharmaceutical compositions comprising the same
US20080188457A1 (en) * 2007-02-02 2008-08-07 Braincells, Inc. Modulation of Neurogenesis with Biguanides and GSK3-beta Agents
KR101226669B1 (ko) * 2007-09-21 2013-01-25 한올바이오파마주식회사 Ｎ,ｎ－디메틸 이미도디카르본이미딕 디아미드의 디카르복실산염, 그의 제조 방법 및 그의 약제학적 조성물
KR101104912B1 (ko) 2008-01-08 2012-01-12 한올바이오파마주식회사 Ｎ,ｎ―디메틸 이미도디카르본이미딕 디아미드의 니코틴산염, 그의 제조방법 및 그를 포함하는 약제학적 조성물
AU2008357111B2 (en) * 2008-06-26 2013-05-09 Laboratorios Silanes, S.A. De C.V. A new metformin Glycinate salt for blood glucose control
US20110021634A1 (en) 2009-06-18 2011-01-27 Patel Pranav Dushyant Processes for preparing metformin hydrochloride
WO2011049400A2 (ko) * 2009-10-23 2011-04-28 한올바이오파마주식회사 N,n-디메틸 이미도디카르본이미딕 디아미드의 산 부가염을 포함하는 항암용 약제학적 조성물
KR101324283B1 (ko) 2010-04-27 2013-11-01 한올바이오파마주식회사 바이구아나이드 화합물의 신규 염, 그의 제조방법, 그를 포함하는 약제학적 조성물
WO2018060962A2 (en) 2016-09-30 2018-04-05 Laboratorios Silanes S.A. De C.V. Metformin amino acid compounds and methods of using the same
WO2018060959A1 (en) 2016-09-30 2018-04-05 Laboratorios Silanes S.A. De C.V. Metformin glycinate, pharmaceutical compositions comprising the same, and methods of using the same
CN107118130A (zh) * 2017-05-11 2017-09-01 杜剑平 一类治疗肿瘤的药物化合物及其应用
CN106986791A (zh) * 2017-05-11 2017-07-28 杜剑平 一种治疗肿瘤的药物化合物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3179562A (en) * 1961-08-23 1965-04-20 Du Pont Treatment of diabetes with alpha, alpha substituted acetic acid derivatives

Also Published As

Publication number Publication date
DK457475A (es) 1976-04-12
PH12279A (en) 1978-12-12
AR209457A1 (es) 1977-04-29
AT343676B (de) 1978-06-12
PL95259B1 (pl) 1977-10-31
SU572200A3 (ru) 1977-09-05
IL48116A (en) 1979-07-25
IE41807L (en) 1976-04-11
BR7506595A (pt) 1976-08-17
FR2287221A1 (fr) 1976-05-07
ZA755861B (en) 1976-08-25
IE41807B1 (en) 1980-03-26
CH602612A5 (es) 1978-07-31
US4028402A (en) 1977-06-07
DE2542598A1 (de) 1976-04-22
JPS51125718A (en) 1976-11-02
FI752626A (es) 1976-04-12
DK140834B (da) 1979-11-26
LU73557A1 (es) 1977-05-24
GB1473256A (en) 1977-05-11
ES441673A1 (es) 1977-04-01
IL48116A0 (en) 1975-11-25
ATA776375A (de) 1977-10-15
SE7511357L (sv) 1976-04-12
NO753447L (es) 1976-04-13
NL7511890A (nl) 1976-04-13
DK140834C (es) 1980-04-28
AU8497775A (en) 1977-03-24
CA1053258A (en) 1979-04-24
DD123322A5 (es) 1976-12-12
BE834369A (fr) 1976-04-12

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