CZ285766B6 - N-[[4-[4-(4-fluorfenoxy)buty/]-4-piperidy/]-N-methylamino]-2-benzothiazololy, způsob jejich výroby, antiarytmické prostředky na jejich bázi a způsob jejich výroby - Google Patents

N-[[4-[4-(4-fluorfenoxy)buty/]-4-piperidy/]-N-methylamino]-2-benzothiazololy, způsob jejich výroby, antiarytmické prostředky na jejich bázi a způsob jejich výroby Download PDF

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Publication number
CZ285766B6
CZ285766B6 CZ953192A CZ319295A CZ285766B6 CZ 285766 B6 CZ285766 B6 CZ 285766B6 CZ 953192 A CZ953192 A CZ 953192A CZ 319295 A CZ319295 A CZ 319295A CZ 285766 B6 CZ285766 B6 CZ 285766B6
Authority
CZ
Czechia
Prior art keywords
fluorophenoxy
butyl
methylamino
piperidyl
benzothiazolol
Prior art date
Application number
CZ953192A
Other languages
Czech (cs)
English (en)
Other versions
CZ319295A3 (en
Inventor
Jozef Jan Pieter Karel Heykants
Marcel Jan Maria Borgers
Doris Wilhelm
Original Assignee
Janssen Pharmaceutica N. V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N. V. filed Critical Janssen Pharmaceutica N. V.
Publication of CZ319295A3 publication Critical patent/CZ319295A3/cs
Publication of CZ285766B6 publication Critical patent/CZ285766B6/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
CZ953192A 1993-06-11 1994-06-06 N-[[4-[4-(4-fluorfenoxy)buty/]-4-piperidy/]-N-methylamino]-2-benzothiazololy, způsob jejich výroby, antiarytmické prostředky na jejich bázi a způsob jejich výroby CZ285766B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93201685 1993-06-11

Publications (2)

Publication Number Publication Date
CZ319295A3 CZ319295A3 (en) 1996-03-13
CZ285766B6 true CZ285766B6 (cs) 1999-11-17

Family

ID=8213890

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ953192A CZ285766B6 (cs) 1993-06-11 1994-06-06 N-[[4-[4-(4-fluorfenoxy)buty/]-4-piperidy/]-N-methylamino]-2-benzothiazololy, způsob jejich výroby, antiarytmické prostředky na jejich bázi a způsob jejich výroby

Country Status (34)

Country Link
US (1) US5691354A (OSRAM)
EP (1) EP0701556B1 (OSRAM)
JP (1) JP3498145B2 (OSRAM)
KR (1) KR100337984B1 (OSRAM)
CN (1) CN1039120C (OSRAM)
AT (1) ATE159254T1 (OSRAM)
AU (1) AU678841B2 (OSRAM)
BG (1) BG62968B1 (OSRAM)
BR (1) BR9406765A (OSRAM)
CA (1) CA2163018A1 (OSRAM)
CZ (1) CZ285766B6 (OSRAM)
DE (1) DE69406284T2 (OSRAM)
DK (1) DK0701556T3 (OSRAM)
ES (1) ES2108471T3 (OSRAM)
FI (1) FI955916A7 (OSRAM)
GR (1) GR3025805T3 (OSRAM)
HU (1) HU221620B1 (OSRAM)
IL (1) IL109975A (OSRAM)
LV (1) LV11544B (OSRAM)
MY (1) MY111222A (OSRAM)
NO (1) NO305123B1 (OSRAM)
NZ (1) NZ268575A (OSRAM)
OA (1) OA10201A (OSRAM)
PH (1) PH31126A (OSRAM)
PL (1) PL176775B1 (OSRAM)
RO (1) RO115523B1 (OSRAM)
RU (1) RU2122546C1 (OSRAM)
SG (1) SG48821A1 (OSRAM)
SI (1) SI9420036A (OSRAM)
SK (1) SK281175B6 (OSRAM)
TW (1) TW282469B (OSRAM)
UA (1) UA41936C2 (OSRAM)
WO (1) WO1994029305A1 (OSRAM)
ZA (1) ZA944106B (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0907650B1 (en) * 1996-06-27 2002-12-04 Janssen Pharmaceutica N.V. N- 4-(heteroarylmethyl)phenyl]-heteroarylamines
CA2398388A1 (en) * 2000-01-20 2001-07-26 Koji Kato Novel piperidine compound and pharmaceutical thereof
RU2242254C2 (ru) * 2002-11-05 2004-12-20 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина Способ диагностики аритмий сердца
RU2246895C2 (ru) * 2002-11-05 2005-02-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ прогнозирования желудочковых аритмий у кардиохирургических больных
RU2261123C2 (ru) * 2003-02-17 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ прогнозирования атриовентрикулярных блокад после радикальной кардиохирургической коррекции пороков сердца у детей раннего возраста
RU2261122C2 (ru) * 2003-02-17 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ определения уровня атриовентрикулярной блокады у больных после хирургической коррекции пороков сердца
RU2261121C2 (ru) * 2003-02-17 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ определения степени зависимости от электрокардиостимулятора
RU2261124C2 (ru) * 2003-04-24 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ оценки электрических свойств рабочего миокарда
RU2261041C2 (ru) * 2003-04-24 2005-09-27 ГУ Новосибирский научно-исследовательский институт патологии кровообращения им. акад. Е.Н. Мешалкина МЗ РФ Способ прогнозирования пароксизмальной эктопической атриовентрикулярной тахикардии

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ16485A3 (cs) * 1984-01-09 1993-12-15 Janssen Pharmaceutica Nv Způsob přípravy 4-/(bicyklyl heterocyklyl) methyl a hetero/-piperidinů
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
US4861785A (en) * 1984-12-03 1989-08-29 Janssen Pharmaceutica N.V. Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents
US5010198A (en) * 1984-12-03 1991-04-23 Janssen Pharmaceutica N.V. Intermediates for the synthesis of benzoxazol- and benzothiazolamine derivatives, useful as anti-anoxic agents
US4749702A (en) * 1985-04-15 1988-06-07 Janssen Pharmaceutica N. V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol

Also Published As

Publication number Publication date
CZ319295A3 (en) 1996-03-13
KR100337984B1 (ko) 2002-10-25
BG100210A (bg) 1996-07-31
SK154495A3 (en) 1996-06-05
NO305123B1 (no) 1999-04-06
HU9501971D0 (en) 1995-09-28
PL311965A1 (en) 1996-03-18
SG48821A1 (en) 1998-05-18
FI955916A0 (fi) 1995-12-08
ZA944106B (en) 1995-12-11
LV11544B (en) 1997-08-20
US5691354A (en) 1997-11-25
CN1125443A (zh) 1996-06-26
CA2163018A1 (en) 1994-12-22
HU221620B1 (hu) 2002-12-28
DK0701556T3 (da) 1998-01-26
ATE159254T1 (de) 1997-11-15
NO954801D0 (no) 1995-11-27
AU7183894A (en) 1995-01-03
UA41936C2 (uk) 2001-10-15
RU2122546C1 (ru) 1998-11-27
PH31126A (en) 1998-02-23
OA10201A (en) 1996-12-18
BG62968B1 (bg) 2000-12-29
MY111222A (en) 1999-09-30
SI9420036A (en) 1996-10-31
GR3025805T3 (en) 1998-03-31
BR9406765A (pt) 1996-02-21
FI955916L (fi) 1995-12-08
NZ268575A (en) 1996-08-27
JP3498145B2 (ja) 2004-02-16
IL109975A0 (en) 1994-10-07
PL176775B1 (pl) 1999-07-30
LV11544A (lv) 1996-10-20
DE69406284T2 (de) 1998-02-19
NO954801L (no) 1995-11-27
CN1039120C (zh) 1998-07-15
EP0701556A1 (en) 1996-03-20
FI955916A7 (fi) 1995-12-08
DE69406284D1 (de) 1997-11-20
RO115523B1 (ro) 2000-03-30
WO1994029305A1 (en) 1994-12-22
SK281175B6 (sk) 2000-12-11
TW282469B (OSRAM) 1996-08-01
EP0701556B1 (en) 1997-10-15
HUT73679A (en) 1996-09-30
IL109975A (en) 1999-04-11
ES2108471T3 (es) 1997-12-16
JPH08511014A (ja) 1996-11-19
AU678841B2 (en) 1997-06-12

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20070606