CY2481B1 - Antifungal combination therapy. - Google Patents

Antifungal combination therapy.

Info

Publication number
CY2481B1
CY2481B1 CY0400076A CY0400076A CY2481B1 CY 2481 B1 CY2481 B1 CY 2481B1 CY 0400076 A CY0400076 A CY 0400076A CY 0400076 A CY0400076 A CY 0400076A CY 2481 B1 CY2481 B1 CY 2481B1
Authority
CY
Cyprus
Prior art keywords
antifungal
inhibitors
combination therapy
combination
xmp
Prior art date
Application number
CY0400076A
Other languages
English (en)
Inventor
Kenneth F Bartizal
George K Abruzzo
Amy M Flattery
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9620739.4A external-priority patent/GB9620739D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CY2481B1 publication Critical patent/CY2481B1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1751Bactericidal/permeability-increasing protein [BPI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CY0400076A 1996-09-12 2004-10-27 Antifungal combination therapy. CY2481B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2632796P 1996-09-12 1996-09-12
GBGB9620739.4A GB9620739D0 (en) 1996-10-04 1996-10-04 Antifungal combination therapy

Publications (1)

Publication Number Publication Date
CY2481B1 true CY2481B1 (en) 2005-06-03

Family

ID=26310166

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0400076A CY2481B1 (en) 1996-09-12 2004-10-27 Antifungal combination therapy.

Country Status (21)

Country Link
EP (1) EP0925070B1 (xx)
JP (1) JP3288051B2 (xx)
KR (1) KR100380871B1 (xx)
CN (1) CN1235554A (xx)
AT (1) ATE248625T1 (xx)
AU (1) AU721334B2 (xx)
CA (1) CA2265824C (xx)
CY (1) CY2481B1 (xx)
CZ (1) CZ88499A3 (xx)
DE (1) DE69724626T2 (xx)
DK (1) DK0925070T3 (xx)
EA (1) EA002469B1 (xx)
EE (1) EE03748B1 (xx)
ES (1) ES2203819T3 (xx)
IL (1) IL128870A0 (xx)
NO (1) NO991207L (xx)
NZ (1) NZ334446A (xx)
PL (1) PL333282A1 (xx)
PT (1) PT925070E (xx)
SK (1) SK29999A3 (xx)
WO (1) WO1998010782A1 (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0753001T3 (da) * 1994-11-08 2000-05-08 Glaxo Wellcome Sa Antifungale sordaridinderivater
US6069126A (en) * 1996-09-12 2000-05-30 Merck & Co., Inc. Antifungal combination therapy
AUPQ066399A0 (en) * 1999-05-31 1999-06-24 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
AUPQ462399A0 (en) * 1999-12-13 2000-01-13 Fujisawa Pharmaceutical Co., Ltd. New use
KR100680464B1 (ko) * 2000-06-28 2007-02-08 주식회사 하이닉스반도체 반도체 소자의 캐패시터 제조 방법
WO2002098463A1 (fr) * 2001-06-05 2002-12-12 The New Industry Research Organization Compositions antifongiques
NZ561675A (en) * 2005-04-07 2010-07-30 Toyama Chemical Co Ltd Pharmaceutical composition and method using antifungal agent in combination
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
AU2007305626B2 (en) 2006-10-06 2013-01-10 Toyama Chemical Co., Ltd. Pharmaceutical composition comprising phenylamidine derivative and method of using the pharmaceutical composition in combination with antifungal agent
TWI426918B (zh) 2007-02-12 2014-02-21 Merck Sharp & Dohme Il-23拮抗劑於治療感染之用途
WO2009129525A2 (en) * 2008-04-18 2009-10-22 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Antifungal and anti-cariogenic cellobio-oligosaccharides produced by dextransucrase
CN102274216B (zh) * 2010-06-10 2013-04-10 吉林大学 一种提高氟康唑抗真菌作用的增效剂
CN102274217B (zh) * 2010-06-10 2013-04-10 吉林大学 三氯生作为抗真菌药物氟康唑增效剂的新用途
CN102274215B (zh) * 2010-06-10 2013-04-10 吉林大学 一种具有与氟康唑协同抗真菌作用的增效剂
EP2636409A1 (en) 2010-11-05 2013-09-11 Eisai R&D Management Co., Ltd. Combined pharmaceutical composition as antifungal agent
RU2013157207A (ru) * 2011-05-24 2015-06-27 БАЙЕР КРОПСАЙЕНС ЭлПи Синергетические комбинации полиеновых фунгицидов и нерибосомальных пептидов и связанные с ними способы применения
CN102319326A (zh) * 2011-07-23 2012-01-18 李玮 一种治疗脚癣的浸药卫生纸
CN115721633B (zh) * 2022-03-25 2024-05-03 山东大学 羟基茜草素在作为t3ss小分子抑制剂中的应用
CN116473985A (zh) * 2023-03-29 2023-07-25 暨南大学 一种多烯类抗真菌药物组合物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds

Also Published As

Publication number Publication date
EA002469B1 (ru) 2002-06-27
DE69724626T2 (de) 2004-07-29
KR20000036054A (ko) 2000-06-26
CZ88499A3 (cs) 1999-10-13
EP0925070B1 (en) 2003-09-03
CA2265824C (en) 2004-11-09
NO991207D0 (no) 1999-03-11
DE69724626D1 (de) 2003-10-09
JP2000503675A (ja) 2000-03-28
EE9900088A (et) 1999-10-15
IL128870A0 (en) 2000-06-01
EE03748B1 (et) 2002-06-17
CA2265824A1 (en) 1998-03-19
WO1998010782A1 (en) 1998-03-19
PT925070E (pt) 2003-12-31
NO991207L (no) 1999-05-11
DK0925070T3 (da) 2003-12-01
PL333282A1 (en) 1999-11-22
AU721334B2 (en) 2000-06-29
KR100380871B1 (ko) 2003-04-18
JP3288051B2 (ja) 2002-06-04
NZ334446A (en) 2000-11-24
SK29999A3 (en) 2000-02-14
CN1235554A (zh) 1999-11-17
ATE248625T1 (de) 2003-09-15
AU4339297A (en) 1998-04-02
ES2203819T3 (es) 2004-04-16
EP0925070A1 (en) 1999-06-30
EA199900283A1 (ru) 1999-08-26

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