CY1789A - Lactam derivatives - Google Patents

Lactam derivatives

Info

Publication number
CY1789A
CY1789A CY178995A CY178995A CY1789A CY 1789 A CY1789 A CY 1789A CY 178995 A CY178995 A CY 178995A CY 178995 A CY178995 A CY 178995A CY 1789 A CY1789 A CY 1789A
Authority
CY
Cyprus
Prior art keywords
group
hydrogen atom
6alkyl
phenyl
phenylc1
Prior art date
Application number
CY178995A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878720695A external-priority patent/GB8720695D0/en
Priority claimed from GB888819382A external-priority patent/GB8819382D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CY1789A publication Critical patent/CY1789A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CY178995A 1987-09-03 1995-10-20 Lactam derivatives CY1789A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878720695A GB8720695D0 (en) 1987-09-03 1987-09-03 Chemical compounds
GB888819382A GB8819382D0 (en) 1988-08-15 1988-08-15 Lactame derivatives

Publications (1)

Publication Number Publication Date
CY1789A true CY1789A (en) 1995-10-20

Family

ID=26292675

Family Applications (1)

Application Number Title Priority Date Filing Date
CY178995A CY1789A (en) 1987-09-03 1995-10-20 Lactam derivatives

Country Status (15)

Country Link
EP (1) EP0306323B1 (fr)
AT (1) ATE111910T1 (fr)
AU (1) AU613662B2 (fr)
CY (1) CY1789A (fr)
CZ (1) CZ404491A3 (fr)
DE (1) DE3851597T2 (fr)
ES (1) ES2060655T3 (fr)
GB (1) GB2209335B (fr)
HK (1) HK75591A (fr)
HU (1) HU211843A9 (fr)
IE (1) IE61669B1 (fr)
IL (1) IL87658A (fr)
NZ (1) NZ226032A (fr)
PH (1) PH25493A (fr)
SK (1) SK404491A3 (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636563A (en) * 1985-09-16 1987-01-13 American Home Products Corporation Antipsychotic γ-carbolines
US4672117A (en) * 1985-09-16 1987-06-09 American Home Products Corporation Antipsychotic gamma-carbolines
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
EP0339959A3 (fr) * 1988-04-27 1991-03-20 Glaxo Group Limited Dérivés de lactame
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
CA1336906C (fr) * 1988-08-02 1995-09-05 Peter Charles North Derives du lactame
JPH02167280A (ja) * 1988-08-15 1990-06-27 Glaxo Group Ltd ラクタム誘導体
GB8820653D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8820650D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
US4997831A (en) * 1988-09-01 1991-03-05 Glaxo Group Limited Lactam derivatives
GB8820651D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
EP0377238A1 (fr) * 1988-12-22 1990-07-11 Duphar International Research B.V Indolo(3,2-c)-lactames annelés
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
GB8904552D0 (en) 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical process
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same
EP0392663A1 (fr) * 1989-03-13 1990-10-17 Ono Pharmaceutical Co., Ltd. Un dérivé de carboline comme antagoniste du récepteur 5-HT3
ZA902794B (en) * 1989-04-18 1991-04-24 Duphar Int Res New 3-n substituted carbamoyl-indole derivatives
DE69004924T2 (de) 1989-04-21 1994-05-19 Sandoz Ag Therapeutische verwendung von 5-ht3-rezeptor-antagonisten.
US5530008A (en) * 1989-04-21 1996-06-25 Sandoz Ltd. Use of 5-HT3 receptor antagonists in treating panic disorders or obsessive compulsive disorders
GB8913646D0 (en) * 1989-06-14 1989-08-02 Glaxo Group Ltd Chemical compounds
US5276050A (en) * 1989-08-01 1994-01-04 Glaxo Group Limited Medicaments
GB8917557D0 (en) * 1989-08-01 1989-09-13 Glaxo Group Ltd Medicaments
US5180728A (en) * 1989-09-25 1993-01-19 Fujisawa Pharmaceutical Company, Ltd. Pyrimidoindole derivatives and processes for preparation thereof
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments
GB8928837D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Pharmaceuticals
GB9011469D0 (en) * 1990-05-23 1990-07-11 Glaxo Group Ltd Chemical process
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5189041A (en) * 1990-11-16 1993-02-23 Syntex (U.S.A.) Inc. Tricyclic 5-ht3 receptor antagonists
GB9721139D0 (en) 1997-10-07 1997-12-03 Glaxo Group Ltd Medicaments
WO2001058869A2 (fr) * 2000-02-11 2001-08-16 Bristol-Myers Squibb Company Modulateurs de recepteurs aux cannabinoides, leurs procedes de preparation et utilisations de modulateurs de recepteurs aux cannabinoides pour le traitement de maladies respiratoires et non respiratoires
EP1465629B1 (fr) 2002-01-18 2007-03-14 Aryx Therapeutics Antagonistes du recepteur 5-ht3 et leurs procedes d'utilisation
RU2544856C2 (ru) 2008-01-25 2015-03-20 Сергей Олегович Бачурин НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
ES2432618T3 (es) 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular
PT2432467T (pt) 2009-05-20 2018-04-04 Inst Nat Sante Rech Med Antagonistas recetores de serotina 5-ht3 para utilização no tratamento de distúrbios vestibulares lesionais

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0191562B1 (fr) * 1985-01-23 1991-07-10 Glaxo Group Limited Dérivés de tétrahydrocarbazolones
CA1336906C (fr) * 1988-08-02 1995-09-05 Peter Charles North Derives du lactame
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same

Also Published As

Publication number Publication date
HK75591A (en) 1991-10-04
IL87658A0 (en) 1989-02-28
ATE111910T1 (de) 1994-10-15
CZ404491A3 (en) 1993-04-14
AU613662B2 (en) 1991-08-08
IE61669B1 (en) 1994-11-16
GB2209335B (en) 1991-05-29
DE3851597T2 (de) 1995-01-26
EP0306323A3 (en) 1990-07-18
HU211843A9 (en) 1995-12-28
IL87658A (en) 1994-06-24
SK404491A3 (en) 2000-12-11
GB8820736D0 (en) 1988-10-05
EP0306323A2 (fr) 1989-03-08
PH25493A (en) 1991-07-24
NZ226032A (en) 1991-12-23
DE3851597D1 (de) 1994-10-27
ES2060655T3 (es) 1994-12-01
IE882669L (en) 1989-03-03
GB2209335A (en) 1989-05-10
AU2174288A (en) 1989-03-09
EP0306323B1 (fr) 1994-09-21

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