CY1789A - Lactam derivatives - Google Patents

Lactam derivatives

Info

Publication number
CY1789A
CY1789A CY178995A CY178995A CY1789A CY 1789 A CY1789 A CY 1789A CY 178995 A CY178995 A CY 178995A CY 178995 A CY178995 A CY 178995A CY 1789 A CY1789 A CY 1789A
Authority
CY
Cyprus
Prior art keywords
group
hydrogen atom
6alkyl
phenyl
phenylc1
Prior art date
Application number
CY178995A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878720695A external-priority patent/GB8720695D0/en
Priority claimed from GB888819382A external-priority patent/GB8819382D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CY1789A publication Critical patent/CY1789A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
CY178995A 1987-09-03 1995-10-20 Lactam derivatives CY1789A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878720695A GB8720695D0 (en) 1987-09-03 1987-09-03 Chemical compounds
GB888819382A GB8819382D0 (en) 1988-08-15 1988-08-15 Lactame derivatives

Publications (1)

Publication Number Publication Date
CY1789A true CY1789A (en) 1995-10-20

Family

ID=26292675

Family Applications (1)

Application Number Title Priority Date Filing Date
CY178995A CY1789A (en) 1987-09-03 1995-10-20 Lactam derivatives

Country Status (15)

Country Link
EP (1) EP0306323B1 (xx)
AT (1) ATE111910T1 (xx)
AU (1) AU613662B2 (xx)
CY (1) CY1789A (xx)
CZ (1) CZ404491A3 (xx)
DE (1) DE3851597T2 (xx)
ES (1) ES2060655T3 (xx)
GB (1) GB2209335B (xx)
HK (1) HK75591A (xx)
HU (1) HU211843A9 (xx)
IE (1) IE61669B1 (xx)
IL (1) IL87658A (xx)
NZ (1) NZ226032A (xx)
PH (1) PH25493A (xx)
SK (1) SK404491A3 (xx)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636563A (en) * 1985-09-16 1987-01-13 American Home Products Corporation Antipsychotic γ-carbolines
US4672117A (en) * 1985-09-16 1987-06-09 American Home Products Corporation Antipsychotic gamma-carbolines
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
EP0339959A3 (en) * 1988-04-27 1991-03-20 Glaxo Group Limited Lactam derivatives
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
FI92067C (fi) * 1988-08-02 1994-09-26 Glaxo Group Ltd Menetelmä valmistaa terapeuttisesti aktiivisia mono- tai disubstituoituja (imidatsol-4-yyli)metyylipyrido/4,3-b/indol- ja atsepino/4,3-b/indol-1-oneja
US5008272A (en) * 1988-08-15 1991-04-16 Glaxo Group Limited Lactam derivatives
GB8820651D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8820650D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
JPH02180885A (ja) * 1988-09-01 1990-07-13 Glaxo Group Ltd ラクタム誘導体
GB8820653D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
EP0377238A1 (en) * 1988-12-22 1990-07-11 Duphar International Research B.V New annelated indolo (3,2-c)-lactams
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same
GB8904552D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical process
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
KR900013959A (ko) * 1989-03-13 1990-10-22 원본미기재 γ-카르블린 또는 그들의 제약학적으로 허용 가능한 산부가염 및/또는 수화물, 및 그들로 구성되는 제약학적 조성물
ZA902794B (en) * 1989-04-18 1991-04-24 Duphar Int Res New 3-n substituted carbamoyl-indole derivatives
AU631632B2 (en) 1989-04-21 1992-12-03 Novartis Ag Therapeutic use of 5-ht3 receptor antagonists
US5530008A (en) * 1989-04-21 1996-06-25 Sandoz Ltd. Use of 5-HT3 receptor antagonists in treating panic disorders or obsessive compulsive disorders
GB8913646D0 (en) * 1989-06-14 1989-08-02 Glaxo Group Ltd Chemical compounds
US5276050A (en) * 1989-08-01 1994-01-04 Glaxo Group Limited Medicaments
GB8917557D0 (en) * 1989-08-01 1989-09-13 Glaxo Group Ltd Medicaments
US5180728A (en) * 1989-09-25 1993-01-19 Fujisawa Pharmaceutical Company, Ltd. Pyrimidoindole derivatives and processes for preparation thereof
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments
GB8928837D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Pharmaceuticals
GB9011469D0 (en) * 1990-05-23 1990-07-11 Glaxo Group Ltd Chemical process
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5189041A (en) * 1990-11-16 1993-02-23 Syntex (U.S.A.) Inc. Tricyclic 5-ht3 receptor antagonists
GB9721139D0 (en) 1997-10-07 1997-12-03 Glaxo Group Ltd Medicaments
CA2399791A1 (en) * 2000-02-11 2001-08-16 Bristol-Myers Squibb Company Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases
EP1465629B1 (en) 2002-01-18 2007-03-14 Aryx Therapeutics 5-ht3 receptor antagonists and methods of use
RU2544856C2 (ru) 2008-01-25 2015-03-20 Сергей Олегович Бачурин НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
JP5955767B2 (ja) 2009-05-20 2016-07-20 インセルム(インスティチュート ナショナル デ ラ サンテ エ デ ラ リシェルシェ メディカル) 損傷性前庭障害の処置における使用のためのセロトニン5−ht3受容体拮抗薬
ES2432618T3 (es) 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3680123D1 (en) * 1985-01-23 1991-08-14 Glaxo Group Ltd Tetrahydrocarbazolonderivate.
FI92067C (fi) * 1988-08-02 1994-09-26 Glaxo Group Ltd Menetelmä valmistaa terapeuttisesti aktiivisia mono- tai disubstituoituja (imidatsol-4-yyli)metyylipyrido/4,3-b/indol- ja atsepino/4,3-b/indol-1-oneja
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same

Also Published As

Publication number Publication date
IE882669L (en) 1989-03-03
GB2209335B (en) 1991-05-29
EP0306323B1 (en) 1994-09-21
EP0306323A2 (en) 1989-03-08
HK75591A (en) 1991-10-04
EP0306323A3 (en) 1990-07-18
DE3851597T2 (de) 1995-01-26
IL87658A (en) 1994-06-24
ATE111910T1 (de) 1994-10-15
IL87658A0 (en) 1989-02-28
CZ404491A3 (en) 1993-04-14
HU211843A9 (en) 1995-12-28
DE3851597D1 (de) 1994-10-27
ES2060655T3 (es) 1994-12-01
GB8820736D0 (en) 1988-10-05
AU2174288A (en) 1989-03-09
IE61669B1 (en) 1994-11-16
GB2209335A (en) 1989-05-10
NZ226032A (en) 1991-12-23
AU613662B2 (en) 1991-08-08
PH25493A (en) 1991-07-24
SK404491A3 (en) 2000-12-11

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