CY1123415T1 - Υπογραφες εκφρασης γονιδιων προγνωστικες της αποκρισης υποκειμενου σε αναστολεα πολυκινασης και μεθοδοι χρησεως αυτων - Google Patents
Υπογραφες εκφρασης γονιδιων προγνωστικες της αποκρισης υποκειμενου σε αναστολεα πολυκινασης και μεθοδοι χρησεως αυτωνInfo
- Publication number
- CY1123415T1 CY1123415T1 CY20201100811T CY201100811T CY1123415T1 CY 1123415 T1 CY1123415 T1 CY 1123415T1 CY 20201100811 T CY20201100811 T CY 20201100811T CY 201100811 T CY201100811 T CY 201100811T CY 1123415 T1 CY1123415 T1 CY 1123415T1
- Authority
- CY
- Cyprus
- Prior art keywords
- polykinase
- methods
- gene expression
- inhibitors
- expression signatures
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 5
- 230000014509 gene expression Effects 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 4
- 201000011510 cancer Diseases 0.000 abstract 4
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013082487 | 2013-08-28 | ||
| PCT/US2014/053142 WO2015031604A1 (en) | 2013-08-28 | 2014-08-28 | Gene expression signatures predictive of subject response to a multi-kinase inhibitor and methods of using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1123415T1 true CY1123415T1 (el) | 2021-12-31 |
Family
ID=52587328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20201100811T CY1123415T1 (el) | 2013-08-28 | 2020-08-28 | Υπογραφες εκφρασης γονιδιων προγνωστικες της αποκρισης υποκειμενου σε αναστολεα πολυκινασης και μεθοδοι χρησεως αυτων |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11136625B2 (enExample) |
| EP (1) | EP3039424B1 (enExample) |
| JP (1) | JP6612232B2 (enExample) |
| CN (1) | CN105659085B (enExample) |
| CY (1) | CY1123415T1 (enExample) |
| DK (1) | DK3039424T3 (enExample) |
| ES (1) | ES2813877T3 (enExample) |
| PT (1) | PT3039424T (enExample) |
| WO (1) | WO2015031604A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6612232B2 (ja) | 2013-08-28 | 2019-11-27 | クラウン バイオサイエンス インコーポレイテッド（タイカン） | 対象のマルチキナーゼ阻害剤に対する応答性を予測する遺伝子発現シグネチャ、及びその使用 |
| WO2017110764A1 (ja) * | 2015-12-24 | 2017-06-29 | 公益財団法人がん研究会 | マルチキナーゼ阻害剤の有効性と安全性を予測する検査方法、検査キット、及びバイオマーカー |
| WO2020085936A1 (ru) * | 2018-10-24 | 2020-04-30 | Общество С Ограниченной Ответственностью "Онкобокс" | Тест-классификатор клинического ответа на лечение сорафенибом индивидуальных пациентов с раком почки |
| JP2022517563A (ja) * | 2019-01-02 | 2022-03-09 | チョーチアン クラウンマブ バイオテック カンパニー リミテッド | タンパク質キナーゼバイオマーカーと組み合わせた、多標的キナーゼ阻害剤を使用したがんの処置 |
| CN111521810B (zh) * | 2019-02-02 | 2024-06-21 | 中国科学院上海药物研究所 | 癌症患者根据脾酪氨酸激酶进行分层 |
| CN111693707A (zh) * | 2020-07-16 | 2020-09-22 | 首都医科大学附属北京朝阳医院 | Rock激酶活性在辅助诊断血管炎患者中的应用 |
| CN118345086B (zh) * | 2024-04-22 | 2024-10-11 | 西部(重庆)科学城种质创制大科学中心 | 柑橘溃疡病抗性Cs7g24050基因及其编码蛋白与应用 |
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| JP6612232B2 (ja) | 2013-08-28 | 2019-11-27 | クラウン バイオサイエンス インコーポレイテッド（タイカン） | 対象のマルチキナーゼ阻害剤に対する応答性を予測する遺伝子発現シグネチャ、及びその使用 |
-
2014
- 2014-08-28 JP JP2016537848A patent/JP6612232B2/ja active Active
- 2014-08-28 PT PT148409444T patent/PT3039424T/pt unknown
- 2014-08-28 WO PCT/US2014/053142 patent/WO2015031604A1/en not_active Ceased
- 2014-08-28 CN CN201480057475.2A patent/CN105659085B/zh active Active
- 2014-08-28 DK DK14840944.4T patent/DK3039424T3/da active
- 2014-08-28 EP EP14840944.4A patent/EP3039424B1/en active Active
- 2014-08-28 US US14/915,121 patent/US11136625B2/en active Active
- 2014-08-28 ES ES14840944T patent/ES2813877T3/es active Active
-
2020
- 2020-08-28 CY CY20201100811T patent/CY1123415T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20160208328A1 (en) | 2016-07-21 |
| EP3039424A4 (en) | 2017-03-29 |
| EP3039424B1 (en) | 2020-07-29 |
| DK3039424T3 (da) | 2020-08-31 |
| CN105659085A (zh) | 2016-06-08 |
| JP6612232B2 (ja) | 2019-11-27 |
| JP2016528914A (ja) | 2016-09-23 |
| EP3039424A1 (en) | 2016-07-06 |
| CN105659085B (zh) | 2018-12-07 |
| US11136625B2 (en) | 2021-10-05 |
| WO2015031604A1 (en) | 2015-03-05 |
| ES2813877T3 (es) | 2021-03-25 |
| PT3039424T (pt) | 2020-09-03 |
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