CY1123121T1 - Συντηγμενες βενζαζεπινες για θεραπεια τραυλισματος - Google Patents
Συντηγμενες βενζαζεπινες για θεραπεια τραυλισματοςInfo
- Publication number
- CY1123121T1 CY1123121T1 CY20201100641T CY201100641T CY1123121T1 CY 1123121 T1 CY1123121 T1 CY 1123121T1 CY 20201100641 T CY20201100641 T CY 20201100641T CY 201100641 T CY201100641 T CY 201100641T CY 1123121 T1 CY1123121 T1 CY 1123121T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- subject
- stuttering
- petrol
- fused
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Η παρούσα εφεύρεση συμπεριλαμβάνει μεθόδους θεραπείας υποκειμένου που τραυλίζει. Οι μέθοδοι μπορεί να περιλαμβάνουν τα στάδια: (a) πιστοποίησης υποκειμένου που έχει ανάγκη θεραπείας• και (b) χορήγησης στο υποκείμενο μιας θεραπευτικώς αποτελεσματικής ποσότητας μιας σύνθεσης που περιλαμβάνει ανταγωνιστή υποδοχέα D1/D5, μερικό αγωνιστή υποδοχέα D1/D5 ή μίγμα αυτών. Για παράδειγμα, ο ανταγωνιστής υποδοχέα D1/D5 μπορεί να είναι ecopipam ή φαρμακευτικώς αποδεκτό άλας, διαλύτωμα, υδρίτης, προφάρμακο, συντακτικό ανάλογο, μεταβολίτης ή πολύμορφο αυτού.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361892841P | 2013-10-18 | 2013-10-18 | |
| PCT/US2014/061080 WO2015058053A1 (en) | 2013-10-18 | 2014-10-17 | Fused benzazepines for treatment of stuttering |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1123121T1 true CY1123121T1 (el) | 2021-10-29 |
Family
ID=52828726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20201100641T CY1123121T1 (el) | 2013-10-18 | 2020-07-10 | Συντηγμενες βενζαζεπινες για θεραπεια τραυλισματος |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9949983B2 (el) |
| EP (1) | EP3057595B1 (el) |
| JP (3) | JP2016533374A (el) |
| AU (1) | AU2014337140B2 (el) |
| CA (1) | CA2927915C (el) |
| CY (1) | CY1123121T1 (el) |
| DK (1) | DK3057595T3 (el) |
| ES (1) | ES2805448T3 (el) |
| HR (1) | HRP20201152T1 (el) |
| HU (1) | HUE049848T2 (el) |
| IL (1) | IL245155B (el) |
| LT (1) | LT3057595T (el) |
| MX (1) | MX370612B (el) |
| PL (1) | PL3057595T3 (el) |
| PT (1) | PT3057595T (el) |
| RS (1) | RS60556B1 (el) |
| SI (1) | SI3057595T1 (el) |
| WO (1) | WO2015058053A1 (el) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE058696T2 (hu) | 2012-07-12 | 2022-09-28 | Emalex Biosciences Inc | Fúzionált benzazepinek a turett-szindróma terápiájában |
| BR112019019242A2 (pt) | 2017-03-30 | 2020-04-14 | Jose Eduardo Penello Temporao | composição multivitamínica para aprimoramento da fluência verbal, dimimuição dos sintomas da ansiedade de performance e seu método e preparação |
| KR102608479B1 (ko) * | 2017-05-25 | 2023-12-01 | 글리테크 엘엘씨. | Nmdar 길항제-반응성 신경정신 질환을 위한 병용 요법 |
| US10786495B2 (en) * | 2017-10-10 | 2020-09-29 | The Regents Of The University Of California | Vesicular monoamine transporter 2 inhibitors for treating stuttering |
| WO2020237247A1 (en) * | 2019-05-23 | 2020-11-26 | India Globalization Capital, Inc. | Compositions and methods using cannabinoids for treating stammering/stutering and symptoms of tourette syndrome |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4477378A (en) | 1980-02-05 | 1984-10-16 | Schering Corp. | Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines |
| US5302716A (en) | 1986-01-16 | 1994-04-12 | Schering Corporation | Fused benzazepines |
| US4973586A (en) | 1986-01-16 | 1990-11-27 | Schering Corporation | Fused benzazepines, compositions of, and medical use thereof |
| BE1005064A4 (nl) | 1991-07-03 | 1993-04-06 | Asm Fico Tooling | Buiginrichting. |
| GB9127306D0 (en) | 1991-12-23 | 1992-02-19 | Boots Co Plc | Therapeutic agents |
| DK0750616T3 (da) | 1994-03-16 | 2001-07-23 | Cenes Ltd | Syreadditionssalte af 2,3,4,5-tetrahydro-1H-3-benzazapinforbindelser |
| IL135659A0 (en) * | 1997-10-28 | 2001-05-20 | Schering Corp | Method of reducing craving in mammals |
| US6132724A (en) * | 1998-04-29 | 2000-10-17 | City Of Hope National Medical Center | Allelic polygene diagnosis of reward deficiency syndrome and treatment |
| SE9904724D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| US8518933B2 (en) * | 2009-04-23 | 2013-08-27 | Abbvie Inc. | Modulators of 5-HT receptors and methods of use thereof |
| US20110206782A1 (en) * | 2010-02-24 | 2011-08-25 | Auspex Pharmaceuticals, Inc. | Piperidine modulators of dopamine receptor |
| WO2012033874A1 (en) | 2010-09-10 | 2012-03-15 | Chipkin Richard E | Method of treating compulsive self-injurious behaviors |
| HUE058696T2 (hu) | 2012-07-12 | 2022-09-28 | Emalex Biosciences Inc | Fúzionált benzazepinek a turett-szindróma terápiájában |
-
2014
- 2014-10-17 SI SI201431621T patent/SI3057595T1/sl unknown
- 2014-10-17 PL PL14854586T patent/PL3057595T3/pl unknown
- 2014-10-17 DK DK14854586.6T patent/DK3057595T3/da active
- 2014-10-17 ES ES14854586T patent/ES2805448T3/es active Active
- 2014-10-17 AU AU2014337140A patent/AU2014337140B2/en active Active
- 2014-10-17 EP EP14854586.6A patent/EP3057595B1/en active Active
- 2014-10-17 HU HUE14854586A patent/HUE049848T2/hu unknown
- 2014-10-17 LT LTEP14854586.6T patent/LT3057595T/lt unknown
- 2014-10-17 CA CA2927915A patent/CA2927915C/en active Active
- 2014-10-17 RS RS20200880A patent/RS60556B1/sr unknown
- 2014-10-17 WO PCT/US2014/061080 patent/WO2015058053A1/en active Application Filing
- 2014-10-17 JP JP2016524108A patent/JP2016533374A/ja not_active Withdrawn
- 2014-10-17 MX MX2016005030A patent/MX370612B/es active IP Right Grant
- 2014-10-17 US US15/030,271 patent/US9949983B2/en active Active
- 2014-10-17 PT PT148545866T patent/PT3057595T/pt unknown
-
2016
- 2016-04-17 IL IL245155A patent/IL245155B/en active IP Right Grant
-
2019
- 2019-06-13 JP JP2019110259A patent/JP7245509B2/ja active Active
-
2020
- 2020-07-10 CY CY20201100641T patent/CY1123121T1/el unknown
- 2020-07-23 HR HRP20201152TT patent/HRP20201152T1/hr unknown
-
2021
- 2021-03-01 JP JP2021031859A patent/JP2021080288A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL245155A0 (en) | 2016-06-30 |
| MX370612B (es) | 2019-12-18 |
| JP2016533374A (ja) | 2016-10-27 |
| NZ719103A (en) | 2021-05-28 |
| JP2021080288A (ja) | 2021-05-27 |
| PL3057595T3 (pl) | 2021-03-08 |
| AU2014337140B2 (en) | 2020-01-30 |
| PT3057595T (pt) | 2020-07-31 |
| EP3057595A1 (en) | 2016-08-24 |
| US9949983B2 (en) | 2018-04-24 |
| IL245155B (en) | 2020-07-30 |
| HUE049848T2 (hu) | 2020-11-30 |
| HRP20201152T1 (hr) | 2020-10-30 |
| EP3057595B1 (en) | 2020-04-29 |
| DK3057595T3 (da) | 2020-08-10 |
| US20160271141A1 (en) | 2016-09-22 |
| RS60556B1 (sr) | 2020-08-31 |
| JP7245509B2 (ja) | 2023-03-24 |
| CA2927915C (en) | 2021-10-26 |
| LT3057595T (lt) | 2020-08-10 |
| MX2016005030A (es) | 2017-01-23 |
| JP2019147843A (ja) | 2019-09-05 |
| WO2015058053A1 (en) | 2015-04-23 |
| SI3057595T1 (sl) | 2020-09-30 |
| AU2014337140A1 (en) | 2016-05-12 |
| EP3057595A4 (en) | 2017-06-07 |
| ES2805448T3 (es) | 2021-02-12 |
| CA2927915A1 (en) | 2015-04-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1123121T1 (el) | Συντηγμενες βενζαζεπινες για θεραπεια τραυλισματος | |
| CY1123595T1 (el) | Παραγωγα χολικου οξεος ως αγωνιστες fxr/tgr5 | |
| CY1122754T1 (el) | Μεθοδοι για την αγωγη της ρινικης πολυποδιασης με την χορηγηση ενος ανταγωνιστη il-4r | |
| CY1119057T1 (el) | Συνδετες υποδοχεα οπιοειδους και μεθοδοι χρησης και κατασκευης αυτων | |
| CY1124669T1 (el) | ΑΝΤΙ-ΟΙΣΤΡΟΓΟΝΙΚΑ ΦΑΡΜΑΚΑ ΤΕΤΡΑΫΔΡΟ-1Η-ΠΥΡΙΔΟ[3,4-b]INΔOΛIOY | |
| CY1125436T1 (el) | Αναστολεις dna-pk | |
| CY1120881T1 (el) | Ανταγωνιστες υποδοχεα 5-ητ3 | |
| CY1123633T1 (el) | Ετεροκυκλικες ενωσεις και οι χρησεις αυτων | |
| CY1123417T1 (el) | Παραγωγα τετρα�δροϊσοκινολινης | |
| CY1124407T1 (el) | Ενωσεις αναστολεα αυτοταξινης | |
| CY1123953T1 (el) | Καθυστερημενης απελευθερωσης συνθεσεις λινακλοτιδης | |
| CY1125068T1 (el) | Ενωσεις τετραϋποκατεστημενου αλκενιου και χρηση αυτων | |
| CY1120334T1 (el) | Υποκατεστημενης 3-αλλογονοαλυλαμινης αναστολεις ssao και χρησεις αυτων | |
| CY1120318T1 (el) | Υποκατεστημενες βενζυλινδαζολες για χρηση ως αναστολεις κινασης bub1 στη θεραπευτικη αντιμετωπιση υπερπολλαπλασιαστικων ασθενειων | |
| CY1120939T1 (el) | Συνδυασμος ρεγοραφενιμπης και ακετυλοσαλικυλικου οξεος για τη θεραπευτικη αντιμετωπιση του ορθοκολικου καρκινου | |
| CY1123059T1 (el) | Αναστολη του διαυλου ιοντων παροδικου δυναμικου του υποδοχεα α1 | |
| CY1119227T1 (el) | Παραγωγα πυριδινης ως ηπιοι αναστολεις της rock | |
| MX2016006891A (es) | Metodos utiles en la sintesis de analogos de halicondrina b. | |
| MD4779B1 (ro) | Compuşi aril sau heteroaril biciclici condensaţi şi utilizarea acestora ca inhibitori IRAK4 | |
| EA201501122A8 (ru) | Новые агонисты соматостатиновых рецепторов подтипа 4 (sstr4) | |
| CR20140413A (es) | Inhibidores de serina/treonina cinasa | |
| CR20150114A (es) | Composición farmacéutica recubierta que contiene regorafenib | |
| CY1122613T1 (el) | Παραγωγα 4-οξο-3,4-διυδρο-1,2,3-βενζοτριαζινης ως ρυθμιστες toy gpr139 | |
| EA201591805A1 (ru) | Оксабицикло [2.2.2] кислоты - модуляторы gpr120 | |
| EA201390977A1 (ru) | Комбинация агониста опиоидных рецепторов и антагониста опиоидных рецепторов для лечения болезни паркинсона |