CY1122469T1 - Υπογλωσσια φαρμακοτεχνικη μορφη ριλουζολης - Google Patents

Υπογλωσσια φαρμακοτεχνικη μορφη ριλουζολης

Info

Publication number
CY1122469T1
CY1122469T1 CY20191101095T CY191101095T CY1122469T1 CY 1122469 T1 CY1122469 T1 CY 1122469T1 CY 20191101095 T CY20191101095 T CY 20191101095T CY 191101095 T CY191101095 T CY 191101095T CY 1122469 T1 CY1122469 T1 CY 1122469T1
Authority
CY
Cyprus
Prior art keywords
rilouzole
pharmaceutical form
sublingual
riluzole
sublingual pharmaceutical
Prior art date
Application number
CY20191101095T
Other languages
Greek (el)
English (en)
Inventor
Vladimir Coric
Robert M. BERMAN
Ronald Samuel VLADYKA
Amgad SALEH
Danny Yu
Original Assignee
Biohaven Therapeutics Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohaven Therapeutics Ltd. filed Critical Biohaven Therapeutics Ltd.
Publication of CY1122469T1 publication Critical patent/CY1122469T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CY20191101095T 2014-11-21 2019-10-22 Υπογλωσσια φαρμακοτεχνικη μορφη ριλουζολης CY1122469T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462083094P 2014-11-21 2014-11-21
PCT/US2015/061114 WO2016081472A1 (en) 2014-11-21 2015-11-17 Sublingual formulation of riluzole

Publications (1)

Publication Number Publication Date
CY1122469T1 true CY1122469T1 (el) 2021-01-27

Family

ID=55085882

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191101095T CY1122469T1 (el) 2014-11-21 2019-10-22 Υπογλωσσια φαρμακοτεχνικη μορφη ριλουζολης

Country Status (24)

Country Link
US (3) US11660267B2 (OSRAM)
EP (3) EP4039247B1 (OSRAM)
JP (3) JP6753860B2 (OSRAM)
KR (2) KR102580378B1 (OSRAM)
CN (1) CN107249567B (OSRAM)
AU (2) AU2015350148B2 (OSRAM)
BR (1) BR112017010423B1 (OSRAM)
CA (1) CA2967662A1 (OSRAM)
CY (1) CY1122469T1 (OSRAM)
DK (1) DK3220891T3 (OSRAM)
EA (1) EA038518B1 (OSRAM)
ES (2) ES2751300T3 (OSRAM)
HR (1) HRP20191892T8 (OSRAM)
HU (1) HUE046869T2 (OSRAM)
IL (2) IL278188B2 (OSRAM)
LT (1) LT3220891T (OSRAM)
MX (1) MX368838B (OSRAM)
PH (1) PH12017500934B1 (OSRAM)
PL (1) PL3220891T3 (OSRAM)
PT (1) PT3220891T (OSRAM)
RS (1) RS59490B1 (OSRAM)
SG (1) SG11201703896QA (OSRAM)
SI (1) SI3220891T1 (OSRAM)
WO (1) WO2016081472A1 (OSRAM)

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JP2021534160A (ja) * 2018-08-16 2021-12-09 バイオヘイブン・セラピューティクス・リミテッドBiohaven Therapeutics Ltd. 疾患処置のためのリルゾール口腔内崩壊錠の使用
MX2022004808A (es) * 2019-10-22 2022-06-08 Arvinas Operations Inc Métodos para tratar el cáncer de próstata.
CN115996918A (zh) 2020-05-09 2023-04-21 阿尔维纳斯运营股份有限公司 制造双官能团化合物的方法、双官能团化合物的超纯形式以及包括所述双官能团化合物的剂型
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CN113876735B (zh) * 2021-10-20 2023-05-12 陇南市第一人民医院 一种利鲁唑微球制剂及其制备方法
KR102625977B1 (ko) 2021-11-24 2024-01-17 부산대학교 산학협력단 리루졸을 유효성분으로 포함하는 염증성 장질환 예방 또는 치료용 조성물
WO2025122895A1 (en) 2023-12-08 2025-06-12 Arvinas Operations, Inc. Use of androgen receptor degrader for the treatment of spinal and bulbar muscular atrophy

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Also Published As

Publication number Publication date
EP3616686B1 (en) 2021-05-19
ES2751300T3 (es) 2020-03-31
HUE046869T2 (hu) 2020-04-28
LT3220891T (lt) 2019-11-11
EA201790958A1 (ru) 2018-01-31
IL278188A (en) 2020-11-30
DK3220891T3 (da) 2019-11-04
AU2021201034B2 (en) 2023-07-06
KR20230135183A (ko) 2023-09-22
MX368838B (es) 2019-10-18
US20180153794A1 (en) 2018-06-07
JP2017535613A (ja) 2017-11-30
PH12017500934A1 (en) 2017-11-20
EP3220891A1 (en) 2017-09-27
IL252285B (en) 2020-10-29
KR102580378B1 (ko) 2023-09-19
HRP20191892T8 (hr) 2020-09-18
IL252285A0 (en) 2017-07-31
BR112017010423B1 (pt) 2023-09-26
RS59490B1 (sr) 2019-12-31
AU2021201034A1 (en) 2021-03-11
EP4039247A2 (en) 2022-08-10
CN107249567A (zh) 2017-10-13
US20250114301A1 (en) 2025-04-10
PH12017500934B1 (en) 2024-06-28
AU2015350148B2 (en) 2020-11-26
CN107249567B (zh) 2021-08-03
MX2017006446A (es) 2018-02-12
US20210038499A1 (en) 2021-02-11
IL278188B1 (en) 2024-11-01
EP3616686A1 (en) 2020-03-04
ES2882783T3 (es) 2021-12-02
HRP20191892T1 (hr) 2020-01-10
EP4039247A3 (en) 2022-11-16
EA038518B1 (ru) 2021-09-09
AU2015350148A1 (en) 2017-06-15
EP3220891B1 (en) 2019-07-24
KR102811263B1 (ko) 2025-05-23
BR112017010423A2 (pt) 2017-12-26
SI3220891T1 (sl) 2020-02-28
KR20170137032A (ko) 2017-12-12
IL278188B2 (en) 2025-03-01
PT3220891T (pt) 2019-10-31
US12121609B2 (en) 2024-10-22
US11660267B2 (en) 2023-05-30
JP2023065398A (ja) 2023-05-12
EP3616686B8 (en) 2021-06-23
WO2016081472A1 (en) 2016-05-26
EP4039247B1 (en) 2025-11-05
PL3220891T3 (pl) 2020-08-24
SG11201703896QA (en) 2017-06-29
JP6753860B2 (ja) 2020-09-09
CA2967662A1 (en) 2016-05-26
JP2021001173A (ja) 2021-01-07

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