CY1119942T1 - Μεθοδοι θεραπειας της ψωριασης χρησιμοποιωντας ανταγωνιστες της il-17 - Google Patents
Μεθοδοι θεραπειας της ψωριασης χρησιμοποιωντας ανταγωνιστες της il-17Info
- Publication number
- CY1119942T1 CY1119942T1 CY20181100220T CY181100220T CY1119942T1 CY 1119942 T1 CY1119942 T1 CY 1119942T1 CY 20181100220 T CY20181100220 T CY 20181100220T CY 181100220 T CY181100220 T CY 181100220T CY 1119942 T1 CY1119942 T1 CY 1119942T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- competitors
- philosophy
- methods
- antibody
- Prior art date
Links
- 102000004554 Interleukin-17 Receptors Human genes 0.000 abstract 2
- 108010017525 Interleukin-17 Receptors Proteins 0.000 abstract 2
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39138810P | 2010-10-08 | 2010-10-08 | |
| PCT/EP2011/067522 WO2012045848A1 (en) | 2010-10-08 | 2011-10-07 | Methods of treating psoriasis using il-17 antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1119942T1 true CY1119942T1 (el) | 2018-12-12 |
Family
ID=44759699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20181100220T CY1119942T1 (el) | 2010-10-08 | 2018-02-22 | Μεθοδοι θεραπειας της ψωριασης χρησιμοποιωντας ανταγωνιστες της il-17 |
Country Status (28)
| Country | Link |
|---|---|
| US (9) | US9717791B2 (enExample) |
| EP (5) | EP2625199B1 (enExample) |
| JP (2) | JP5537740B2 (enExample) |
| KR (3) | KR20130110179A (enExample) |
| CN (2) | CN103154031A (enExample) |
| AU (1) | AU2011311482B2 (enExample) |
| BR (1) | BR112013008501A2 (enExample) |
| CA (1) | CA2813900C (enExample) |
| CL (1) | CL2013000930A1 (enExample) |
| CY (1) | CY1119942T1 (enExample) |
| DK (1) | DK2625199T3 (enExample) |
| ES (1) | ES2660770T3 (enExample) |
| HK (1) | HK1247932A1 (enExample) |
| HR (1) | HRP20180301T1 (enExample) |
| HU (1) | HUE038334T2 (enExample) |
| IL (1) | IL225310A (enExample) |
| LT (1) | LT2625199T (enExample) |
| MA (1) | MA34646B1 (enExample) |
| MX (1) | MX356279B (enExample) |
| NO (1) | NO2625199T3 (enExample) |
| PH (1) | PH12013500660B1 (enExample) |
| PL (1) | PL2625199T3 (enExample) |
| PT (1) | PT2625199T (enExample) |
| RU (2) | RU2591083C2 (enExample) |
| SG (1) | SG188979A1 (enExample) |
| SI (1) | SI2625199T1 (enExample) |
| TW (2) | TWI548419B (enExample) |
| WO (1) | WO2012045848A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7833527B2 (en) | 2006-10-02 | 2010-11-16 | Amgen Inc. | Methods of treating psoriasis using IL-17 Receptor A antibodies |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| IN2012DN06720A (enExample) | 2010-01-15 | 2015-10-23 | Kirin Amgen Inc | |
| KR20130080790A (ko) | 2010-05-20 | 2013-07-15 | 아블린쓰 엔.브이. | Ｈｅｒ３와 관련된 생물학적 물질들 |
| SI3757126T1 (sl) | 2010-11-05 | 2025-12-31 | Novartis Ag | Postopki za zdravljenje psoriatičnega artritisa z antagonisti il-17 |
| UA117218C2 (uk) | 2011-05-05 | 2018-07-10 | Мерк Патент Гмбх | Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f |
| RU2014125071A (ru) * | 2011-11-21 | 2015-12-27 | Новартис Аг | Способы лечения псориатического артрита (psa) с использованием антагонистов il-17 и аллелей ответа psa или отсутствия ответа psa |
| EP2968488A1 (en) * | 2013-03-15 | 2016-01-20 | Amgen Inc. | Methods for treating psoriasis using an anti-il-23 antibody |
| NZ712294A (en) * | 2013-03-15 | 2020-04-24 | Amgen Inc | Methods for treating crohn’s disease using an anti-il23 antibody |
| EP3033107A1 (en) * | 2013-08-15 | 2016-06-22 | Novartis AG | Methods of treating generalized pustular psoriasis (gpp) using il-17 antagonists |
| CA2935046C (en) * | 2013-12-27 | 2021-04-13 | Osaka University | Vaccine targeting il-17a |
| RU2577228C2 (ru) * | 2014-03-14 | 2016-03-10 | Закрытое Акционерное Общество "Биокад" | Анти-il-17-антитела, способ их получения и способ применения |
| JP6596014B2 (ja) * | 2014-03-31 | 2019-10-23 | アムジェン ケー・エー，インコーポレイテッド | 爪および頭皮乾癬の治療方法 |
| JP2017521479A (ja) | 2014-05-15 | 2017-08-03 | ラニ セラピューティクス， エルエルシー | ポリペプチドおよび／またはタンパク質を含む固体塊の薬学的組成物およびそれを製造するための方法 |
| US11548940B2 (en) | 2014-05-15 | 2023-01-10 | Rani Therapeutics, Llc | Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| SG11201701276SA (en) * | 2014-08-26 | 2017-03-30 | Kirin Amgen Inc | Method for treating psoriasis patient which received anti-tnf-alpha antibody therapy |
| JP2017528465A (ja) * | 2014-09-10 | 2017-09-28 | ノバルティス アーゲー | 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ−１７アンタゴニストの使用 |
| AR103172A1 (es) * | 2014-12-22 | 2017-04-19 | Novartis Ag | Reducción selectiva de residuos de cisteina en anticuerpos il-17 |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| US10500273B2 (en) | 2015-03-02 | 2019-12-10 | 180 Therapeutics Lp | Method of treating a localized fibrotic disorder using an IL-33 antagonist |
| EP3167892A1 (en) | 2015-11-10 | 2017-05-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for preventing or treating imflammatory bowel diseases |
| JP6931648B2 (ja) * | 2015-10-27 | 2021-09-08 | ユーシービー バイオファルマ エスアールエル | 抗ｉｌ−１７ａ／ｆ抗体を用いた治療方法 |
| US20190194311A1 (en) | 2016-07-19 | 2019-06-27 | Novartis Ag | Methods of treating new-onset plaque type psoriasis using il-17 antagonists |
| WO2018096467A1 (en) * | 2016-11-28 | 2018-05-31 | Novartis Ag | Methods of treating acne using interleukin-17 (il-17) antagonists |
| WO2018158741A1 (en) * | 2017-03-03 | 2018-09-07 | Novartis Ag | Psoriasis disease modification following long-term treatment with an il-17 antagonist |
| CN111032691A (zh) * | 2017-08-23 | 2020-04-17 | 伊莱利利公司 | 生殖器银屑病的治疗 |
| TWI725532B (zh) * | 2018-09-11 | 2021-04-21 | 美商美國禮來大藥廠 | 治療牛皮癬之方法 |
| US20220267432A1 (en) | 2019-07-30 | 2022-08-25 | Jiangsu Hengrui Medicine Co., Ltd. | Method for treating autoimmune disease by il-17 antagonist |
| CN114981302A (zh) | 2019-09-20 | 2022-08-30 | 诺华股份有限公司 | 使用白细胞介素-17(il-17)拮抗剂治疗自身免疫性疾病的方法 |
| WO2022127842A1 (zh) * | 2020-12-17 | 2022-06-23 | 上海华奥泰生物药业股份有限公司 | 靶向il-17a和il-36r的双特异性抗体及其应用 |
| WO2022184114A1 (zh) * | 2021-03-03 | 2022-09-09 | 苏州盛迪亚生物医药有限公司 | 抗il-17抗体治疗自身免疫性疾病和炎症的方法 |
| WO2023186174A1 (en) * | 2022-04-01 | 2023-10-05 | Zai Lab (Shanghai) Co., Ltd. | Topical formulation comprising an il-17a binding molecule and uses thereof |
| CN116593718B (zh) * | 2023-07-18 | 2023-09-15 | 军科正源（北京）药物研究有限责任公司 | 用于检测司库奇尤单抗抗药性抗体的试剂 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9422306D0 (en) * | 1994-11-04 | 1994-12-21 | Sandoz Ltd | Organic compounds |
| US6093745A (en) * | 1997-11-25 | 2000-07-25 | Psorx, L.L.C. | Methods and composition for treating skin proliferative diseases |
| AU2002224417A1 (en) * | 2000-10-18 | 2002-04-29 | Immunex Corporation | Methods for treating il-18 mediated disorders |
| US20090280065A1 (en) * | 2006-04-10 | 2009-11-12 | Willian Mary K | Uses and Compositions for Treatment of Psoriasis |
| TWI439284B (zh) * | 2004-04-09 | 2014-06-01 | Abbvie Biotechnology Ltd | 用於治療ＴＮＦα相關失調症之多重可變劑量療法 |
| GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
| CN101296706B (zh) * | 2005-09-01 | 2011-11-30 | 先灵公司 | Il-23和il-17拮抗剂治疗自身免疫性眼部炎性疾病的用途 |
| PL1963368T6 (pl) * | 2005-12-13 | 2021-02-08 | Eli Lilly And Company | Przeciwciała anty-IL-17 |
| TW200815469A (en) * | 2006-06-23 | 2008-04-01 | Astrazeneca Ab | Compounds |
| RU2367429C2 (ru) | 2007-01-30 | 2009-09-20 | Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН | Способ лечения псориаза |
| WO2008150490A2 (en) * | 2007-06-01 | 2008-12-11 | Abbott Biotechnology Ltd. | Uses and compositions for treatment of psoriasis and crohn's disease |
| RU2341272C1 (ru) | 2007-10-22 | 2008-12-20 | Левон Никитович Мкртчян | Средство для неспецифической иммунотерапии |
| JP5581323B2 (ja) | 2008-09-29 | 2014-08-27 | ロシュ グリクアート アクチェンゲゼルシャフト | ヒトｉｌ１７に対する抗体およびその使用 |
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2011
- 2011-10-07 EP EP11764764.4A patent/EP2625199B1/en active Active
- 2011-10-07 BR BR112013008501A patent/BR112013008501A2/pt active Search and Examination
- 2011-10-07 HR HRP20180301TT patent/HRP20180301T1/hr unknown
- 2011-10-07 CA CA2813900A patent/CA2813900C/en active Active
- 2011-10-07 NO NO11764764A patent/NO2625199T3/no unknown
- 2011-10-07 RU RU2013120957/15A patent/RU2591083C2/ru active
- 2011-10-07 PH PH1/2013/500660A patent/PH12013500660B1/en unknown
- 2011-10-07 SI SI201131408T patent/SI2625199T1/en unknown
- 2011-10-07 TW TW100136608A patent/TWI548419B/zh active
- 2011-10-07 MX MX2013003916A patent/MX356279B/es active IP Right Grant
- 2011-10-07 EP EP25216056.9A patent/EP4670788A2/en active Pending
- 2011-10-07 WO PCT/EP2011/067522 patent/WO2012045848A1/en not_active Ceased
- 2011-10-07 PT PT117647644T patent/PT2625199T/pt unknown
- 2011-10-07 KR KR1020137011792A patent/KR20130110179A/ko not_active Ceased
- 2011-10-07 KR KR1020147018691A patent/KR101620771B1/ko active Active
- 2011-10-07 LT LTEP11764764.4T patent/LT2625199T/lt unknown
- 2011-10-07 EP EP17195148.6A patent/EP3299390A1/en not_active Withdrawn
- 2011-10-07 AU AU2011311482A patent/AU2011311482B2/en active Active
- 2011-10-07 RU RU2016120615A patent/RU2665954C1/ru active
- 2011-10-07 PL PL11764764T patent/PL2625199T3/pl unknown
- 2011-10-07 ES ES11764764.4T patent/ES2660770T3/es active Active
- 2011-10-07 EP EP20187002.9A patent/EP3792281A1/en not_active Ceased
- 2011-10-07 CN CN2011800487322A patent/CN103154031A/zh active Pending
- 2011-10-07 SG SG2013018486A patent/SG188979A1/en unknown
- 2011-10-07 US US13/876,367 patent/US9717791B2/en active Active
- 2011-10-07 IL IL225310A patent/IL225310A/en active IP Right Grant
- 2011-10-07 HU HUE11764764A patent/HUE038334T2/hu unknown
- 2011-10-07 CN CN201710261381.2A patent/CN107029234A/zh active Pending
- 2011-10-07 TW TW105116323A patent/TWI564022B/zh active
- 2011-10-07 JP JP2013532213A patent/JP5537740B2/ja active Active
- 2011-10-07 EP EP22186296.4A patent/EP4137514A1/en active Pending
- 2011-10-07 KR KR1020147036815A patent/KR20150018595A/ko not_active Withdrawn
- 2011-10-07 DK DK11764764.4T patent/DK2625199T3/en active
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2013
- 2013-04-05 CL CL2013000930A patent/CL2013000930A1/es unknown
- 2013-05-03 MA MA35872A patent/MA34646B1/fr unknown
- 2013-12-09 JP JP2013253745A patent/JP2014114288A/ja not_active Withdrawn
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2017
- 2017-06-22 US US15/630,577 patent/US10583190B2/en active Active
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2018
- 2018-02-22 CY CY20181100220T patent/CY1119942T1/el unknown
- 2018-06-01 HK HK18107225.2A patent/HK1247932A1/en unknown
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2019
- 2019-12-19 US US16/720,351 patent/US11534490B2/en active Active
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2020
- 2020-12-18 US US17/127,738 patent/US20210113688A1/en not_active Abandoned
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2021
- 2021-02-02 US US17/165,724 patent/US20210162044A1/en not_active Abandoned
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2022
- 2022-12-02 US US18/061,227 patent/US20230321231A1/en active Pending
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2024
- 2024-12-16 US US18/983,037 patent/US20250161445A1/en active Pending
- 2024-12-16 US US18/983,034 patent/US20250161444A1/en active Pending
- 2024-12-16 US US18/983,030 patent/US20250161443A1/en active Pending
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