CY1119188T1 - Αντιμικροβιακα συντηρητικα για την επιτευξη φαρμακοτεχνικης μορφης πολλαπλης δοσης χρησιμοποιωντας βητα-κυκλοεξτρινες για υγρες μορφες δοσολογιας - Google Patents
Αντιμικροβιακα συντηρητικα για την επιτευξη φαρμακοτεχνικης μορφης πολλαπλης δοσης χρησιμοποιωντας βητα-κυκλοεξτρινες για υγρες μορφες δοσολογιαςInfo
- Publication number
- CY1119188T1 CY1119188T1 CY20171100843T CY171100843T CY1119188T1 CY 1119188 T1 CY1119188 T1 CY 1119188T1 CY 20171100843 T CY20171100843 T CY 20171100843T CY 171100843 T CY171100843 T CY 171100843T CY 1119188 T1 CY1119188 T1 CY 1119188T1
- Authority
- CY
- Cyprus
- Prior art keywords
- extrinsic
- cyclo
- achievement
- beta
- liquids
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Abstract
Η παρούσα εφεύρεση κατευθύνεται σε φαρμακευτικές συνθέσεις που περιέχουν θεραπευτικώς αποτελεσματική ποσότητα δραστικού φαρμακευτικού συστατικού ("API"), φαρμακευτικώς αποδεκτή κυκλοδεξτρίνη και φαρμακευτικώς αποδεκτό συντηρητικό. Η εφεύρεση επίσης κατευθύνεται σε φαρμακευτικές συνθέσεις των ενώσεων του Τύπου (I) όπου R2 επιλέγεται από την ομάδα που αποτελείται από μεθύλ, αιθύλ, ισοπροπύλ, δευτ.-βουτύλ και τ-βουτύλ και φαρμακευτικώς αποδεκτή κυκλοδεξτρίνη και συντηρητικό. Τύπος (I): Ειδικότερα, η εφεύρεση κατευθύνεται σε φαρμακευτικές συνθέσεις της ένωσης του τύπου 1a και φαρμακευτικώς αποδεκτή κυκλοδεξτρίνη και συντηρητικό.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54089704P | 2004-01-30 | 2004-01-30 | |
PCT/IB2005/000100 WO2005082416A2 (en) | 2004-01-30 | 2005-01-17 | Antimicrobial preservatives to achieve multi-dose formulation using beta-cyclodextrins for liquid dosage forms |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1119188T1 true CY1119188T1 (el) | 2018-02-14 |
Family
ID=34910697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20171100843T CY1119188T1 (el) | 2004-01-30 | 2017-08-04 | Αντιμικροβιακα συντηρητικα για την επιτευξη φαρμακοτεχνικης μορφης πολλαπλης δοσης χρησιμοποιωντας βητα-κυκλοεξτρινες για υγρες μορφες δοσολογιας |
Country Status (25)
Country | Link |
---|---|
US (1) | US8183230B2 (el) |
EP (1) | EP1713504B1 (el) |
JP (1) | JP5021318B2 (el) |
KR (1) | KR100834232B1 (el) |
CN (1) | CN101090735A (el) |
AR (2) | AR047469A1 (el) |
AU (1) | AU2005216709B2 (el) |
BR (1) | BRPI0506496B8 (el) |
CA (1) | CA2554346C (el) |
CO (1) | CO5700794A2 (el) |
CY (1) | CY1119188T1 (el) |
DK (1) | DK1713504T3 (el) |
ES (1) | ES2638113T3 (el) |
HU (1) | HUE034099T2 (el) |
IL (1) | IL176676A0 (el) |
LT (1) | LT1713504T (el) |
NO (1) | NO20063858L (el) |
NZ (1) | NZ548236A (el) |
PL (1) | PL1713504T3 (el) |
PT (1) | PT1713504T (el) |
RU (1) | RU2332997C2 (el) |
SI (1) | SI1713504T1 (el) |
TW (1) | TW200524632A (el) |
WO (1) | WO2005082416A2 (el) |
ZA (1) | ZA200605148B (el) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG10201506273PA (en) * | 2011-11-29 | 2015-09-29 | Jurox Pty Ltd | Methods of preserving injectable pharmaceutical compositions comprising a cyclodextrin and a hydrophobic drug |
AU2013273764B2 (en) * | 2011-11-29 | 2016-05-05 | Zoetis Services Llc | Pharmaceutical compositions |
KR102455648B1 (ko) * | 2013-07-19 | 2022-10-19 | 베링거잉겔하임베트메디카게엠베하 | 보존된 에테르화된 사이클로덱스트린 유도체 함유 액체 수성 약제학적 조성물 |
NL2015865B1 (en) | 2015-11-27 | 2017-06-13 | Le Vet B V | Maropitant Formulation. |
AU2018251604B2 (en) | 2017-04-10 | 2022-04-14 | Chase Therapeutics Corporation | NK1-antagonist combination and method for treating synucleinopathies |
EP3645120A4 (en) | 2017-06-30 | 2021-03-24 | Chase Pharmaceuticals Corporation | NK-1 ANTAGONIST COMPOSITIONS AND METHODS OF USE IN THE TREATMENT OF DEPRESSION |
CA3129648A1 (en) * | 2019-02-15 | 2020-08-20 | Saol International Limited | Injectable phenol formulations and methods of their use |
EP3725298A1 (en) | 2019-04-16 | 2020-10-21 | Faes Farma, S.A. | Stable and preserved pharmaceutical compositions of bilastine |
CN112370451A (zh) * | 2020-12-08 | 2021-02-19 | 河北科技大学 | 一种枸橼酸马罗匹坦包合物、注射液及制备方法 |
Family Cites Families (22)
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JPS5910510A (ja) * | 1982-07-08 | 1984-01-20 | Nippon Zenyaku Kogyo Kk | 低刺激性チアムリン注射剤 |
JPS59152320A (ja) * | 1983-02-17 | 1984-08-31 | Takeda Chem Ind Ltd | 水性製剤 |
JPS6419737A (en) * | 1987-07-15 | 1989-01-23 | Hitachi Ltd | Multilayer interconnection tape carrier |
JPH039848A (ja) * | 1989-06-06 | 1991-01-17 | Canon Inc | 液体噴射記録装置 |
KR100214905B1 (ko) | 1991-05-31 | 1999-08-02 | 디. 제이. 우드, 스피겔 알렌 제이 | 퀴누클리딘 유도체 |
US5602112A (en) * | 1992-06-19 | 1997-02-11 | Supergen, Inc. | Pharmaceutical formulation |
EP0668863B1 (en) | 1992-11-12 | 1997-01-08 | Pfizer Inc. | Quinuclidine derivative as substance p antagonist |
US5393762A (en) | 1993-06-04 | 1995-02-28 | Pfizer Inc. | Pharmaceutical agents for treatment of emesis |
EP1109581A1 (en) | 1998-09-02 | 2001-06-27 | Allergan Sales, Inc. | Preserved cyclodextrin-containing compositions |
US6255320B1 (en) | 1999-06-01 | 2001-07-03 | Pfizer Inc. | Polymorphs of a crystalline azo-bicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions |
AU5975700A (en) | 1999-07-02 | 2001-01-22 | Janssen Pharmaceutica N.V. | Nasal formulation of an antifungal |
US7163681B2 (en) * | 2000-08-07 | 2007-01-16 | Centocor, Inc. | Anti-integrin antibodies, compositions, methods and uses |
US7034013B2 (en) | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
US20030055023A1 (en) * | 2001-03-20 | 2003-03-20 | Rajewski Roger A. | Formulations containing etomidate and a sulfoalkyl ether cyclodextrin |
CZ200434A3 (cs) | 2001-07-20 | 2005-02-16 | Pfizer Products Inc. | Léčivo pro léčení abnormálního úzkosného chování u domácích zvířat a způsob screeningu zkoušené sloučeniny za účelem stanovení anxiolytické účinnosti u psů |
US20040019012A1 (en) | 2002-02-22 | 2004-01-29 | Singh Satish K. | Ophthalmic antibiotic drug formulations containing a cyclodextrin compound and cetyl pyridinium chloride |
US6869939B2 (en) | 2002-05-04 | 2005-03-22 | Cydex, Inc. | Formulations containing amiodarone and sulfoalkyl ether cyclodextrin |
DE10228049A1 (de) | 2002-06-24 | 2004-01-15 | Merck Patent Gmbh | Flüssige Zubereitung enthaltend Oligopeptide |
US6861526B2 (en) | 2002-10-16 | 2005-03-01 | Pfizer Inc. | Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine |
US20070155782A1 (en) | 2004-01-30 | 2007-07-05 | Hickman Mary A | Nk-1 receptor antagonists anesthesia recovery |
MXPA06008648A (es) | 2004-01-30 | 2006-09-04 | Pfizer Prod Inc | Composiciones farmaceuticas de antagonistas del receptor de neuroquinina y ciclodextrina y metodos para una tolerancia mejorada en el sitio de inyeccion. |
PT1713801E (pt) | 2004-02-02 | 2008-02-11 | Pfizer Prod Inc | Processo para a preparação de 1-(2s,3s)-2-benzidril-n-(5- -terc-butil-2-metoxibenzil)-quinuclidina-3-amina |
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2005
- 2005-01-17 CA CA002554346A patent/CA2554346C/en active Active
- 2005-01-17 PL PL05702263T patent/PL1713504T3/pl unknown
- 2005-01-17 WO PCT/IB2005/000100 patent/WO2005082416A2/en active Application Filing
- 2005-01-17 PT PT57022634T patent/PT1713504T/pt unknown
- 2005-01-17 DK DK05702263.4T patent/DK1713504T3/en active
- 2005-01-17 CN CNA2005800032849A patent/CN101090735A/zh active Pending
- 2005-01-17 HU HUE05702263A patent/HUE034099T2/en unknown
- 2005-01-17 EP EP05702263.4A patent/EP1713504B1/en active Active
- 2005-01-17 AU AU2005216709A patent/AU2005216709B2/en active Active
- 2005-01-17 BR BRPI0506496A patent/BRPI0506496B8/pt active IP Right Grant
- 2005-01-17 KR KR1020067015283A patent/KR100834232B1/ko active IP Right Grant
- 2005-01-17 US US10/588,070 patent/US8183230B2/en active Active
- 2005-01-17 LT LTEP05702263.4T patent/LT1713504T/lt unknown
- 2005-01-17 SI SI200532166T patent/SI1713504T1/sl unknown
- 2005-01-17 ES ES05702263.4T patent/ES2638113T3/es active Active
- 2005-01-17 NZ NZ548236A patent/NZ548236A/en unknown
- 2005-01-17 RU RU2006127422/15A patent/RU2332997C2/ru not_active IP Right Cessation
- 2005-01-17 JP JP2006550330A patent/JP5021318B2/ja active Active
- 2005-01-27 AR ARP050100283A patent/AR047469A1/es not_active Application Discontinuation
- 2005-01-28 TW TW094102680A patent/TW200524632A/zh unknown
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2006
- 2006-06-22 ZA ZA200605148A patent/ZA200605148B/en unknown
- 2006-07-03 IL IL176676A patent/IL176676A0/en unknown
- 2006-07-26 CO CO06073023A patent/CO5700794A2/es not_active Application Discontinuation
- 2006-08-29 NO NO20063858A patent/NO20063858L/no not_active Application Discontinuation
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2017
- 2017-08-04 CY CY20171100843T patent/CY1119188T1/el unknown
- 2017-08-16 AR ARP170102291A patent/AR109357A2/es not_active Application Discontinuation
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