CY1119066T1 - Αναστολεις κρυσταλλικης βρωμο-περιοχης - Google Patents

Αναστολεις κρυσταλλικης βρωμο-περιοχης

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Publication number
CY1119066T1
CY1119066T1 CY20171100702T CY171100702T CY1119066T1 CY 1119066 T1 CY1119066 T1 CY 1119066T1 CY 20171100702 T CY20171100702 T CY 20171100702T CY 171100702 T CY171100702 T CY 171100702T CY 1119066 T1 CY1119066 T1 CY 1119066T1
Authority
CY
Cyprus
Prior art keywords
broom
suspensions
crystal
area
ethanesulfonamide
Prior art date
Application number
CY20171100702T
Other languages
English (en)
Inventor
Yuchuan Gong
Original Assignee
Abbvie Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc. filed Critical Abbvie Inc.
Publication of CY1119066T1 publication Critical patent/CY1119066T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
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    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P11/08—Bronchodilators
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
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    • A61P17/00—Drugs for dermatological disorders
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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    • A61P3/00—Drugs for disorders of the metabolism
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Abstract

Ν-[4-(2,4-διφθοροφαινοξυ)-3-(6-μεθυλ-7-οξο-6,7-διϋδρο-1Η-πυρρολο[2,3-c]πυριδιν-4-υλ)φαινυλ]αιθανοσουλφοναμίδιο και κρυσταλλικές μορφές αυτού είναι κατάλληλα φαρμακευτικά συστατικά για φαρμακευτικές συνθέσεις χρήσιμες στη θεραπευτική αγωγή νόσου, για παράδειγμα, καρκίνου.
CY20171100702T 2013-06-28 2017-07-03 Αναστολεις κρυσταλλικης βρωμο-περιοχης CY1119066T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361840777P 2013-06-28 2013-06-28
PCT/US2014/044513 WO2014210425A1 (en) 2013-06-28 2014-06-27 Crystalline bromodomain inhibitors

Publications (1)

Publication Number Publication Date
CY1119066T1 true CY1119066T1 (el) 2018-01-10

Family

ID=51261220

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Application Number Title Priority Date Filing Date
CY20171100702T CY1119066T1 (el) 2013-06-28 2017-07-03 Αναστολεις κρυσταλλικης βρωμο-περιοχης

Country Status (33)

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US (3) US9321765B2 (el)
EP (1) EP3013826B1 (el)
JP (1) JP6423425B2 (el)
KR (1) KR102323829B1 (el)
CN (1) CN105473586B (el)
AR (1) AR096758A1 (el)
AU (2) AU2014302252B2 (el)
BR (1) BR112015032736A2 (el)
CA (1) CA2916221C (el)
CL (1) CL2015003722A1 (el)
CR (1) CR20160036A (el)
CY (1) CY1119066T1 (el)
DK (1) DK3013826T3 (el)
DO (1) DOP2015000304A (el)
ES (1) ES2636939T3 (el)
HK (2) HK1223354A1 (el)
HR (1) HRP20171154T1 (el)
IL (1) IL243202B (el)
LT (1) LT3013826T (el)
ME (1) ME02801B (el)
MX (1) MX360065B (el)
NZ (1) NZ631112A (el)
PE (1) PE20160287A1 (el)
PH (1) PH12015502792A1 (el)
PL (1) PL3013826T3 (el)
PT (1) PT3013826T (el)
RS (1) RS56318B1 (el)
RU (1) RU2675268C2 (el)
SG (1) SG11201510692TA (el)
SI (1) SI3013826T1 (el)
TW (1) TWI639594B (el)
UY (1) UY35632A (el)
WO (1) WO2014210425A1 (el)

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JP2016525090A (ja) 2016-08-22
EP3013826B1 (en) 2017-05-10
BR112015032736A2 (pt) 2017-07-25
CN105473586B (zh) 2019-11-05
MX2015017435A (es) 2016-08-12
KR20160025021A (ko) 2016-03-07
SG11201510692TA (en) 2016-01-28
TW201534608A (zh) 2015-09-16
PL3013826T3 (pl) 2017-10-31
AU2018201986A1 (en) 2018-04-12
TWI639594B (zh) 2018-11-01
WO2014210425A1 (en) 2014-12-31
JP6423425B2 (ja) 2018-11-14
PH12015502792A1 (en) 2016-03-21
RS56318B1 (sr) 2017-12-29
HRP20171154T1 (hr) 2017-10-20
RU2016102591A (ru) 2017-08-03
LT3013826T (lt) 2017-08-10
CL2015003722A1 (es) 2016-07-29
MX360065B (es) 2018-10-22
SI3013826T1 (sl) 2017-10-30
AU2014302252A1 (en) 2015-12-24
US20170066765A1 (en) 2017-03-09
ES2636939T3 (es) 2017-10-10
CA2916221A1 (en) 2014-12-31
IL243202B (en) 2019-07-31
KR102323829B1 (ko) 2021-11-09
DOP2015000304A (es) 2016-02-29
CR20160036A (es) 2016-05-17
PE20160287A1 (es) 2016-05-22
US9321765B2 (en) 2016-04-26
RU2016102591A3 (el) 2018-04-25
DK3013826T3 (en) 2017-08-28
US20150005340A1 (en) 2015-01-01
HK1223354A1 (zh) 2017-07-28
AU2014302252B2 (en) 2018-03-22
CN105473586A (zh) 2016-04-06
NZ631112A (en) 2018-03-23
AR096758A1 (es) 2016-02-03
RU2675268C2 (ru) 2018-12-18
HK1224298A1 (zh) 2017-08-18
ME02801B (me) 2018-01-20
PT3013826T (pt) 2017-08-11
IL243202A0 (en) 2016-02-29
EP3013826A1 (en) 2016-05-04
CA2916221C (en) 2022-08-30
US20160237085A1 (en) 2016-08-18
UY35632A (es) 2015-01-30

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