CY1117749T1 - Μεθοδος παρασκευης σωματιδιων για χρηση σε φαρμακευτικη συνθεση - Google Patents

Μεθοδος παρασκευης σωματιδιων για χρηση σε φαρμακευτικη συνθεση

Info

Publication number
CY1117749T1
CY1117749T1 CY20161100553T CY161100553T CY1117749T1 CY 1117749 T1 CY1117749 T1 CY 1117749T1 CY 20161100553 T CY20161100553 T CY 20161100553T CY 161100553 T CY161100553 T CY 161100553T CY 1117749 T1 CY1117749 T1 CY 1117749T1
Authority
CY
Cyprus
Prior art keywords
particles
pharmaceutical composition
preparation
provides
active
Prior art date
Application number
CY20161100553T
Other languages
English (en)
Inventor
John Staniforth
Matthew Michael James Green
David Alexander Vodden Morton
Original Assignee
Vectura Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27447911&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1117749(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0029261A external-priority patent/GB0029261D0/en
Priority claimed from GB0030946A external-priority patent/GB0030946D0/en
Priority claimed from PCT/GB2001/001606 external-priority patent/WO2001076575A2/en
Priority claimed from GB0124010A external-priority patent/GB0124010D0/en
Application filed by Vectura Limited filed Critical Vectura Limited
Publication of CY1117749T1 publication Critical patent/CY1117749T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Abstract

Η εφεύρεση παρέχει μια μέθοδο παρασκευής σύνθετων δραστικών σωματιδίων για χρήση σε φαρμακευτική σύνθεση για πνευμονική χορήγηση, όπου η μέθοδος περιλαμβάνει ένα στάδιο άλεσης στο οποίο τα σωματίδια δραστικής ουσίας αλέθονται στην παρουσία σωματίων μιας πρόσθετης ουσίας η οποία είναι κατάλληλη για την προώθηση της διασποράς των σύνθετων δραστικών σωματιδίων με την ενεργοποίηση ενός εισπνευστήρα. Η εφεύρεση παρέχει επίσης συνθέσεις για εισπνοή που παρασκευάζονται με την μέθοδο.
CY20161100553T 2000-11-30 2016-06-21 Μεθοδος παρασκευης σωματιδιων για χρηση σε φαρμακευτικη συνθεση CY1117749T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0029261A GB0029261D0 (en) 2000-11-30 2000-11-30 Method of making particles for use in a pharmaceutical composition
GB0030946A GB0030946D0 (en) 2000-12-19 2000-12-19 Method of making particles for use in a pharmaceutical composition
PCT/GB2001/001606 WO2001076575A2 (en) 2000-04-07 2001-04-09 The treatment of respiratory diseases
GB0124010A GB0124010D0 (en) 2001-10-05 2001-10-05 Pharmaceutical compositions for inhalation
EP01998328.7A EP1337240B2 (en) 2000-11-30 2001-11-30 Method of making particles for use in a pharmaceutical composition

Publications (1)

Publication Number Publication Date
CY1117749T1 true CY1117749T1 (el) 2017-05-17

Family

ID=27447911

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20161100553T CY1117749T1 (el) 2000-11-30 2016-06-21 Μεθοδος παρασκευης σωματιδιων για χρηση σε φαρμακευτικη συνθεση
CY20171101010T CY1119400T1 (el) 2000-11-30 2017-09-26 Μεθοδος παρασκευης σωματιδιων για χρηση σε φαρμακευτικη συνθεση

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY20171101010T CY1119400T1 (el) 2000-11-30 2017-09-26 Μεθοδος παρασκευης σωματιδιων για χρηση σε φαρμακευτικη συνθεση

Country Status (10)

Country Link
EP (2) EP1337241B1 (el)
JP (1) JP4380988B2 (el)
AU (3) AU2002222118A1 (el)
CA (1) CA2429665C (el)
CY (2) CY1117749T1 (el)
DE (1) DE60132239T2 (el)
DK (1) DK2283818T3 (el)
ES (1) ES2296831T3 (el)
NZ (1) NZ526059A (el)
WO (2) WO2002043702A2 (el)

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US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
DE50211045D1 (de) * 2001-03-30 2007-11-22 Jagotec Ag Medizinische aerosolformulierungen
GB0208742D0 (en) * 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
EP1429749A2 (en) 2001-09-26 2004-06-23 Baxter International Inc. Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
AU2003217950A1 (en) * 2002-03-05 2003-09-22 Cleveland State University Agglomerated particles for aerosol drug delivery
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
CN102688224A (zh) * 2003-04-14 2012-09-26 维克特拉有限公司 用于提高剂量效率的药物组合物和装置
WO2004093848A2 (en) 2003-04-14 2004-11-04 Vectura Ltd Dry power inhaler devices and dry power formulations for enhancing dosing efficiency
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
CA2538997A1 (en) * 2003-09-15 2005-03-24 Vectura Limited Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation
GB0321607D0 (en) 2003-09-15 2003-10-15 Vectura Ltd Manufacture of pharmaceutical compositions
US20050287077A1 (en) * 2004-02-10 2005-12-29 James E. Shipley Process for preparing stable SOL of pharmaceutical ingredients and hydrofluorocarbon
GB0409703D0 (en) * 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
GB0410399D0 (en) * 2004-05-10 2004-06-16 Arakis Ltd The treatment of respiratory disease
GB0418791D0 (en) * 2004-08-23 2004-09-22 Glaxo Group Ltd Novel process
GB0425758D0 (en) * 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
GB0426301D0 (en) * 2004-11-30 2004-12-29 Vectura Ltd Pharmaceutical formulations
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GB0525254D0 (en) 2005-12-12 2006-01-18 Jagotec Ag Powder compositions for inhalation
GB0613161D0 (en) 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
GB0801876D0 (en) * 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations
CA2763941A1 (en) 2009-05-29 2010-12-02 Pearl Therapeutics, Inc. Compositions, methods & systems for respiratory delivery of two or more active agents
DE102009049470A1 (de) * 2009-10-15 2011-04-28 Süd-Chemie AG Verfahren zur Herstellung von feinteiligen Lithiumtitan-Spinellen und deren Verwendung
GB0921481D0 (en) 2009-12-08 2010-01-20 Vectura Ltd Process and product
RU2555772C2 (ru) * 2009-12-14 2015-07-10 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Микрочастицы с антибиотиком для ингаляции
SG184352A1 (en) * 2010-04-01 2012-10-30 Chiesi Farma Spa Process for preparing carrier particles for dry powders for inhalation
ITUD20100112A1 (it) * 2010-06-09 2011-12-10 Farma Derma S R L Preparazione per uso vaginale e rettale e relativo procedimento di produzione
TW201304822A (zh) 2010-11-15 2013-02-01 Vectura Ltd 組成物及用途
WO2012073025A1 (en) 2010-11-30 2012-06-07 Vectura Limited Glucosaminoglucans such as heparin for use in the treatment of pulmonary inflammation such as copd
US9763965B2 (en) 2012-04-13 2017-09-19 Glaxosmithkline Intellectual Property Development Limited Aggregate particles
ES2821528T3 (es) 2012-11-14 2021-04-26 Grace W R & Co Composiciones que contienen un material biológicamente activo y un óxido inorgánico no ordenado
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
TR201407010A2 (tr) 2014-06-16 2015-12-21 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Vilanterol formülasyonları.
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Also Published As

Publication number Publication date
WO2002043702A3 (en) 2002-10-17
CA2429665C (en) 2013-10-22
CA2429665A1 (en) 2002-06-06
DE60132239T2 (de) 2008-05-08
EP1337240A2 (en) 2003-08-27
ES2296831T3 (es) 2008-05-01
DK2283818T3 (en) 2017-10-16
EP1337241B1 (en) 2008-01-02
WO2002043701A2 (en) 2002-06-06
EP1337240B1 (en) 2011-07-27
WO2002043701A3 (en) 2002-10-17
EP1337241A2 (en) 2003-08-27
CY1119400T1 (el) 2018-02-14
WO2002043702A2 (en) 2002-06-06
EP1337240B2 (en) 2014-09-24
JP4380988B2 (ja) 2009-12-09
AU2211502A (en) 2002-06-11
AU2002222118A1 (en) 2002-06-11
AU2002222115B2 (en) 2006-09-28
NZ526059A (en) 2005-05-27
DE60132239D1 (de) 2008-02-14
JP2004514504A (ja) 2004-05-20

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