ATE446085T1 - Partikel zur verwendung in einer pharmazeutischen zusammensetzung - Google Patents
Partikel zur verwendung in einer pharmazeutischen zusammensetzungInfo
- Publication number
- ATE446085T1 ATE446085T1 AT01998327T AT01998327T ATE446085T1 AT E446085 T1 ATE446085 T1 AT E446085T1 AT 01998327 T AT01998327 T AT 01998327T AT 01998327 T AT01998327 T AT 01998327T AT E446085 T1 ATE446085 T1 AT E446085T1
- Authority
- AT
- Austria
- Prior art keywords
- particles
- pharmaceutical composition
- dry powder
- additive material
- active particles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0029261A GB0029261D0 (en) | 2000-11-30 | 2000-11-30 | Method of making particles for use in a pharmaceutical composition |
GB0030946A GB0030946D0 (en) | 2000-12-19 | 2000-12-19 | Method of making particles for use in a pharmaceutical composition |
GB0124009A GB0124009D0 (en) | 2001-10-05 | 2001-10-05 | Particles for use in a pharmaceutical composition |
PCT/GB2001/005305 WO2002043700A2 (en) | 2000-11-30 | 2001-11-30 | Particles for use in a pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE446085T1 true ATE446085T1 (de) | 2009-11-15 |
Family
ID=27255994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01998327T ATE446085T1 (de) | 2000-11-30 | 2001-11-30 | Partikel zur verwendung in einer pharmazeutischen zusammensetzung |
Country Status (8)
Country | Link |
---|---|
US (3) | US8580306B2 (de) |
EP (3) | EP1337239B2 (de) |
AT (1) | ATE446085T1 (de) |
AU (1) | AU2002220857A1 (de) |
DE (1) | DE60140268D1 (de) |
ES (2) | ES2334642T5 (de) |
PT (1) | PT1337239E (de) |
WO (1) | WO2002043700A2 (de) |
Families Citing this family (33)
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GB9515182D0 (en) * | 1995-07-24 | 1995-09-20 | Co Ordinated Drug Dev | Improvements in and relating to powders for use in dry powder inhalers |
GB0009469D0 (en) | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formalities for use in inhaler devices |
ATE378039T1 (de) * | 2000-06-27 | 2007-11-15 | Vectura Ltd | Herstellungsverfahren für partikel zur verwendung in einer arzneizusammensetzung |
EP2283818B1 (de) | 2000-11-30 | 2017-08-02 | Vectura Limited | Herstellungsverfahren für Partikel zur Verwendung in einer Arrzneizusammensetzung |
CA2429665C (en) † | 2000-11-30 | 2013-10-22 | Vectura Limited | Method of making particles for use in a pharmaceutical composition |
US8580306B2 (en) * | 2000-11-30 | 2013-11-12 | Vectura Limited | Particles for use in a pharmaceutical composition |
US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
US20120321717A1 (en) * | 2003-04-14 | 2012-12-20 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
US20060147389A1 (en) * | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
GB0321607D0 (en) * | 2003-09-15 | 2003-10-15 | Vectura Ltd | Manufacture of pharmaceutical compositions |
GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
GB0425758D0 (en) * | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
GB0426301D0 (en) * | 2004-11-30 | 2004-12-29 | Vectura Ltd | Pharmaceutical formulations |
GB0525254D0 (en) | 2005-12-12 | 2006-01-18 | Jagotec Ag | Powder compositions for inhalation |
CA2631492A1 (en) * | 2005-12-15 | 2007-06-21 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for oral administration |
GB0712316D0 (en) * | 2007-06-26 | 2007-08-01 | Entripneur Ltd | A novel powder and its method of manufacture |
US9072664B2 (en) | 2008-05-22 | 2015-07-07 | 3M Innovative Properties Company | Process for manufacturing flowable powder drug compositions |
WO2009158300A1 (en) | 2008-06-26 | 2009-12-30 | 3M Innovative Properties Company | Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof |
WO2010002613A2 (en) | 2008-07-02 | 2010-01-07 | 3M Innovative Properties Company | Method of making a dry powder pharmaceutical composition |
ES2739352T3 (es) | 2009-02-26 | 2020-01-30 | Glaxo Group Ltd | Formulaciones farmacéuticas que comprenden 4-{(1R)-2-[(6-{2-[(2,6-diclorobencil)oxi]etoxi}hexil)amino]-1-hidroxietil}-2-(hidroximetil)fenol |
GB0921075D0 (en) | 2009-12-01 | 2010-01-13 | Glaxo Group Ltd | Novel combination of the therapeutic agents |
CA2784207C (en) * | 2009-12-14 | 2018-06-05 | Chiesi Farmaceutici S.P.A. | Antibiotic microparticles for inhalation |
JP6267685B2 (ja) | 2012-04-13 | 2018-01-24 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited | 集合粒子 |
JP5087182B1 (ja) * | 2012-06-13 | 2012-11-28 | クリニプロ株式会社 | 吸入用パウダーの製造方法 |
US20170333359A1 (en) * | 2014-10-20 | 2017-11-23 | Rx Analytic, Inc | A drug-containing micro particle |
CN107106641B (zh) | 2014-10-31 | 2021-12-21 | 葛兰素史密斯克莱知识产权发展有限公司 | 粉末制剂 |
AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
WO2017035408A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
AU2017290593A1 (en) | 2016-06-27 | 2019-01-03 | Achillion Pharmaceuticals, Inc. | Quinazoline and indole compounds to treat medical disorders |
BR112020006609A2 (pt) * | 2017-10-02 | 2020-10-06 | Board Of Regents, The University Of Texas System | composição inalável de clofazimina e seus métodos de uso |
JP2021519337A (ja) | 2018-03-26 | 2021-08-10 | シー4 セラピューティクス, インコーポレイテッド | Ikarosの分解のためのセレブロン結合剤 |
US20230022157A1 (en) | 2018-08-20 | 2023-01-26 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
EP3866773A4 (de) | 2018-10-16 | 2022-10-26 | Georgia State University Research Foundation, Inc. | Kohlenmonoxid-prodrugs zur behandlung von erkrankungen |
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GB124009A (en) | 1918-01-12 | 1919-03-12 | Walter Edward Kimber | Improvements in and connected with the Manufacture of Tools for Turning, Planing, Boring and similar purposes. |
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IT1309592B1 (it) | 1999-03-05 | 2002-01-24 | Chiesi Farma Spa | Particelle veicolo modificate da utilizzarsi nella preparazione diformulazioni farmaceutiche sotto forma di polimeri per inalazione e |
BR9917246A (pt) | 1999-03-05 | 2002-03-26 | Chiesi Farma Spa | Composições farmacêuticas avançadas em pó para inalação |
ES2193069T3 (es) * | 1999-04-14 | 2003-11-01 | Glaxo Group Ltd | Formulacion farmaceutica en aerosol. |
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ITMI991582A1 (it) | 1999-07-16 | 2001-01-16 | Chiesi Farma Spa | Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala |
US6197369B1 (en) * | 1999-09-30 | 2001-03-06 | New Jersey Institute Of Technology | Method of particle coating |
GB0008660D0 (en) | 2000-04-07 | 2000-05-31 | Arakis Ltd | The treatment of respiratory diseases |
GB0009468D0 (en) * | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formulations for use in inhaler devices |
GB0009469D0 (en) * | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formalities for use in inhaler devices |
PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
ATE378039T1 (de) * | 2000-06-27 | 2007-11-15 | Vectura Ltd | Herstellungsverfahren für partikel zur verwendung in einer arzneizusammensetzung |
US6404772B1 (en) * | 2000-07-27 | 2002-06-11 | Symbol Technologies, Inc. | Voice and data wireless communications network and method |
WO2002030394A2 (en) | 2000-10-09 | 2002-04-18 | 3M Innovative Properties Company | Medicinal aerosol formulations |
SI1292281T1 (en) | 2000-10-12 | 2004-12-31 | Boehringer Ingelheim Pharma | Novel tiotropium-containing inhalation powder |
EP2283818B1 (de) * | 2000-11-30 | 2017-08-02 | Vectura Limited | Herstellungsverfahren für Partikel zur Verwendung in einer Arrzneizusammensetzung |
GB0124009D0 (en) | 2001-10-05 | 2001-11-28 | Vectura Ltd | Particles for use in a pharmaceutical composition |
US8580306B2 (en) * | 2000-11-30 | 2013-11-12 | Vectura Limited | Particles for use in a pharmaceutical composition |
US20060147389A1 (en) | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
GB0321607D0 (en) | 2003-09-15 | 2003-10-15 | Vectura Ltd | Manufacture of pharmaceutical compositions |
EP1663164A2 (de) | 2003-09-15 | 2006-06-07 | Vectura Limited | Verfahren zur herstellung von pharmazeutischen zusammensetzungen |
-
2001
- 2001-11-30 US US10/433,135 patent/US8580306B2/en not_active Expired - Lifetime
- 2001-11-30 EP EP01998327.9A patent/EP1337239B2/de not_active Expired - Lifetime
- 2001-11-30 AU AU2002220857A patent/AU2002220857A1/en not_active Abandoned
- 2001-11-30 DE DE60140268T patent/DE60140268D1/de not_active Expired - Lifetime
- 2001-11-30 PT PT01998327T patent/PT1337239E/pt unknown
- 2001-11-30 ES ES01998327.9T patent/ES2334642T5/es not_active Expired - Lifetime
- 2001-11-30 EP EP09173566.2A patent/EP2168571B1/de not_active Expired - Lifetime
- 2001-11-30 AT AT01998327T patent/ATE446085T1/de active
- 2001-11-30 WO PCT/GB2001/005305 patent/WO2002043700A2/en not_active Application Discontinuation
- 2001-11-30 ES ES09173566.2T patent/ES2689704T3/es not_active Expired - Lifetime
- 2001-11-30 EP EP10185079A patent/EP2292212A3/de not_active Withdrawn
-
2013
- 2013-10-10 US US14/050,819 patent/US9585839B2/en not_active Expired - Lifetime
-
2017
- 2017-02-15 US US15/433,106 patent/US10238601B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20040071635A1 (en) | 2004-04-15 |
US20170216202A1 (en) | 2017-08-03 |
EP1337239B1 (de) | 2009-10-21 |
EP1337239A2 (de) | 2003-08-27 |
ES2334642T5 (es) | 2016-03-07 |
US9585839B2 (en) | 2017-03-07 |
EP2168571A2 (de) | 2010-03-31 |
EP2292212A3 (de) | 2012-08-08 |
WO2002043700A3 (en) | 2002-10-24 |
PT1337239E (pt) | 2010-01-26 |
EP2168571A3 (de) | 2011-11-16 |
EP2292212A2 (de) | 2011-03-09 |
US10238601B2 (en) | 2019-03-26 |
US8580306B2 (en) | 2013-11-12 |
ES2334642T3 (es) | 2010-03-15 |
DE60140268D1 (de) | 2009-12-03 |
EP1337239B2 (de) | 2015-11-25 |
EP2168571B1 (de) | 2018-08-22 |
WO2002043700A2 (en) | 2002-06-06 |
ES2689704T3 (es) | 2018-11-15 |
US20140037737A1 (en) | 2014-02-06 |
AU2002220857A1 (en) | 2002-06-11 |
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