CY1114492T1 - Συνδυασμος αλφα 7 νικοτινικων αγωνιστων και αντιψυχωσικων - Google Patents
Συνδυασμος αλφα 7 νικοτινικων αγωνιστων και αντιψυχωσικωνInfo
- Publication number
- CY1114492T1 CY1114492T1 CY20131100896T CY131100896T CY1114492T1 CY 1114492 T1 CY1114492 T1 CY 1114492T1 CY 20131100896 T CY20131100896 T CY 20131100896T CY 131100896 T CY131100896 T CY 131100896T CY 1114492 T1 CY1114492 T1 CY 1114492T1
- Authority
- CY
- Cyprus
- Prior art keywords
- antipsychotic
- fighters
- nicotine
- alpha combination
- alpha
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title 1
- 230000000561 anti-psychotic effect Effects 0.000 title 1
- 229960002715 nicotine Drugs 0.000 title 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title 1
- 239000000164 antipsychotic agent Substances 0.000 abstract 1
- 239000000181 nicotinic agonist Substances 0.000 abstract 1
- 239000011885 synergistic combination Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2828208P | 2008-02-13 | 2008-02-13 | |
| EP09709577.2A EP2254598B1 (en) | 2008-02-13 | 2009-02-13 | Combination of alpha 7 nicotinic agonists and antipsychotics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1114492T1 true CY1114492T1 (el) | 2016-10-05 |
Family
ID=40902222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20131100896T CY1114492T1 (el) | 2008-02-13 | 2013-10-10 | Συνδυασμος αλφα 7 νικοτινικων αγωνιστων και αντιψυχωσικων |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20110059947A1 (https=) |
| EP (2) | EP2254598B1 (https=) |
| JP (1) | JP2011511845A (https=) |
| KR (1) | KR20100113163A (https=) |
| CN (2) | CN103143023A (https=) |
| AU (1) | AU2009214625A1 (https=) |
| BR (1) | BRPI0907570A2 (https=) |
| CA (1) | CA2715268A1 (https=) |
| CO (1) | CO6290706A2 (https=) |
| CY (1) | CY1114492T1 (https=) |
| DK (1) | DK2254598T3 (https=) |
| EC (1) | ECSP10010471A (https=) |
| ES (1) | ES2430622T3 (https=) |
| HR (1) | HRP20130749T1 (https=) |
| IL (1) | IL207389A0 (https=) |
| MX (1) | MX2010008875A (https=) |
| NZ (1) | NZ587312A (https=) |
| PL (1) | PL2254598T3 (https=) |
| PT (1) | PT2254598E (https=) |
| RS (1) | RS52941B (https=) |
| RU (1) | RU2481123C2 (https=) |
| SG (1) | SG188144A1 (https=) |
| SI (1) | SI2254598T1 (https=) |
| WO (1) | WO2009102962A2 (https=) |
| ZA (1) | ZA201005999B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8314119B2 (en) | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
| SA08290475B1 (ar) * | 2007-08-02 | 2013-06-22 | Targacept Inc | (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه |
| CN103180321A (zh) | 2010-09-23 | 2013-06-26 | Abbvie公司 | 氮杂金刚烷衍生物的一水合物 |
| TW201242600A (en) * | 2011-01-18 | 2012-11-01 | Targacept Inc | Treatment of cognitive dysfunction in schizophrenia |
| US9139576B2 (en) | 2011-05-03 | 2015-09-22 | Merck Sharp & Dohme Corp. | Aminomethyl biaryl benzotriazole derivatives |
| WO2014054635A1 (ja) * | 2012-10-02 | 2014-04-10 | 大日本住友製薬株式会社 | イミダゾール誘導体 |
| JP6807094B2 (ja) * | 2016-04-29 | 2021-01-06 | 国立大学法人秋田大学 | クロザピン又はその誘導体の血中薬剤濃度上昇リスク判定方法及び薬剤投与量判定方法 |
| ES2769286T3 (es) | 2016-12-20 | 2020-06-25 | Lts Lohmann Therapie Systeme Ag | Sistema terapéutico transdérmico que contiene asenapina |
| WO2018115010A1 (en) | 2016-12-20 | 2018-06-28 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene |
| CN108727416B (zh) * | 2017-04-20 | 2021-03-09 | 北京大学 | 三环杂芳香体系酰胺衍生物及其制备和用途 |
| ES2881783T3 (es) | 2017-06-26 | 2021-11-30 | Lts Lohmann Therapie Systeme Ag | Sistema terapéutico transdérmico que contiene asenapina y polímero de acrílico y silicona |
| CN107469087A (zh) * | 2017-09-10 | 2017-12-15 | 孙永丽 | 用于治疗精神病的制剂 |
| CA3101420A1 (en) | 2018-06-20 | 2019-12-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| CN112533593A (zh) | 2018-06-20 | 2021-03-19 | 罗曼治疗系统股份公司 | 含有阿塞那平的透皮治疗系统 |
| JP2024502470A (ja) * | 2021-01-08 | 2024-01-19 | アイエフエム デュー インコーポレイテッド | Ｓｔｉｎｇ活性に関連する状態を治療するための化合物および組成物 |
| TW202235073A (zh) | 2021-01-08 | 2022-09-16 | 美商Ｉｆｍ Ｄｕｅ有限公司 | 用於治療與sting活性相關的病狀之化合物及組合物 |
| DE102022114269A1 (de) | 2022-06-07 | 2023-12-07 | Rational Aktiengesellschaft | Gargerät mit einem Selbstreinigungssystem sowie ein Verfahren zum Ändern von Reinigungsparametern für das Gargerät |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5597919A (en) * | 1995-01-06 | 1997-01-28 | Dull; Gary M. | Pyrimidinyl or Pyridinyl alkenyl amine compounds |
| US5712270A (en) | 1995-11-06 | 1998-01-27 | American Home Products Corporation | 2-arylamidothiazole derivatives with CNS activity |
| US5616716A (en) | 1996-01-06 | 1997-04-01 | Dull; Gary M. | (3-(5-ethoxypyridin)yl)-alkenyl 1 amine compounds |
| SE9600683D0 (sv) | 1996-02-23 | 1996-02-23 | Astra Ab | Azabicyclic esters of carbamic acids useful in therapy |
| US5663356A (en) | 1996-04-23 | 1997-09-02 | Ruecroft; Graham | Method for preparation of aryl substituted alefinic secondary amino compounds |
| AR013184A1 (es) | 1997-07-18 | 2000-12-13 | Astrazeneca Ab | Aminas heterociclicas espiroazobiciclicas, composicion farmaceutica, uso de dichas aminas para preparar medicamentos y metodo de tratamiento o profilaxis |
| EP1083889B1 (en) | 1998-06-01 | 2003-12-10 | Ortho-McNeil Pharmaceutical, Inc. | Tetrahydronaphtalene compounds and their use for the treatment of neurodegenerative diseases |
| US6953855B2 (en) * | 1998-12-11 | 2005-10-11 | Targacept, Inc. | 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| SE9904176D0 (sv) | 1999-11-18 | 1999-11-18 | Astra Ab | New use |
| CZ20021880A3 (cs) * | 1999-12-10 | 2002-08-14 | Wyeth | Farmaceutický prostředek |
| CZ294251B6 (cs) * | 2000-06-27 | 2004-11-10 | Laboratorios S. A. L. V. A. T., S. A. | Karbamáty a jejich použití pro výrobu farmaceutického prostředku |
| US6479510B2 (en) | 2000-08-18 | 2002-11-12 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl compounds for treatment of disease |
| US6492386B2 (en) | 2000-08-18 | 2002-12-10 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl compounds for treatment of disease |
| US6486172B2 (en) | 2000-08-18 | 2002-11-26 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl compounds for treatment of disease |
| US6599916B2 (en) | 2000-08-21 | 2003-07-29 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
| WO2002017358A2 (en) | 2000-08-21 | 2002-02-28 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic acetylcholine receptor antagonists) |
| EP1311505A2 (en) | 2000-08-21 | 2003-05-21 | PHARMACIA & UPJOHN COMPANY | Quinuclidine-substituted heteroaryl moieties for treatment of disease ( nicotinic acetylcholine receptor ligands ) |
| US6554086B1 (en) * | 2000-10-27 | 2003-04-29 | Invacare Corporation | Obstacle traversing wheelchair |
| JP4445704B2 (ja) | 2000-12-22 | 2010-04-07 | アルミラル・ソシエダッド・アノニマ | キヌクリジンカルバメート誘導体およびｍ３アンダゴニストとしてのそれらの使用 |
| AU2003217275A1 (en) * | 2002-02-19 | 2003-09-09 | Pharmacia And Upjohn Company | Azabicyclic compounds for the treatment of disease |
| EA200500738A1 (ru) * | 2002-12-06 | 2005-12-29 | ФАРМАЦИЯ ЭНД АПДЖОН КОМПАНИ ЭлЭлСи | КРИСТАЛЛИЧЕСКИЕ ФУМАРАТНЫЕ СОЛИ 1-АЗАБИЦИКЛО [2.2.2]ОКТЗАМЕЩЕННОГО ФУРО [2,3-c] ПИРИДИНИЛКАРБОКСАМИДА И ИХ КОМПОЗИЦИИ И ПОЛУЧЕНИЕ |
| TW200502222A (en) * | 2003-04-02 | 2005-01-16 | Novartis Ag | Use of 10-hydroxy-10,11-dihydrocarbamazepine derivatives for the treatment of affective disorders |
| WO2004099202A1 (en) * | 2003-05-05 | 2004-11-18 | Pharmacia & Upjohn Company Llc | Quinuclidines substituted bentodioxine carboxamides for the treatment of neurodegenerative diseases |
| US7309699B2 (en) * | 2003-12-22 | 2007-12-18 | Abbott Laboratories | 3-Quinuclidinyl amino-substituted biaryl derivatives |
| WO2005063296A2 (en) * | 2003-12-23 | 2005-07-14 | Pfizer Products Inc. | Therapeutic combination for cognition enhancement and psychotic disorders |
| EP1863485A2 (en) * | 2005-03-18 | 2007-12-12 | Abbott Laboratories | Alpha7 neuronal nicotinic receptor ligand and antipsychotic compositions |
-
2009
- 2009-02-13 JP JP2010546920A patent/JP2011511845A/ja active Pending
- 2009-02-13 CN CN2013100500436A patent/CN103143023A/zh active Pending
- 2009-02-13 PT PT97095772T patent/PT2254598E/pt unknown
- 2009-02-13 MX MX2010008875A patent/MX2010008875A/es not_active Application Discontinuation
- 2009-02-13 EP EP09709577.2A patent/EP2254598B1/en active Active
- 2009-02-13 WO PCT/US2009/034062 patent/WO2009102962A2/en not_active Ceased
- 2009-02-13 KR KR1020107020088A patent/KR20100113163A/ko not_active Ceased
- 2009-02-13 DK DK09709577.2T patent/DK2254598T3/da active
- 2009-02-13 ES ES09709577T patent/ES2430622T3/es active Active
- 2009-02-13 PL PL09709577T patent/PL2254598T3/pl unknown
- 2009-02-13 AU AU2009214625A patent/AU2009214625A1/en not_active Abandoned
- 2009-02-13 SG SG2013010327A patent/SG188144A1/en unknown
- 2009-02-13 RS RS20130387A patent/RS52941B/sr unknown
- 2009-02-13 HR HRP20130749AT patent/HRP20130749T1/hr unknown
- 2009-02-13 CA CA2715268A patent/CA2715268A1/en not_active Abandoned
- 2009-02-13 BR BRPI0907570A patent/BRPI0907570A2/pt not_active IP Right Cessation
- 2009-02-13 RU RU2010137787/15A patent/RU2481123C2/ru not_active IP Right Cessation
- 2009-02-13 EP EP13167089.5A patent/EP2633868A1/en not_active Withdrawn
- 2009-02-13 NZ NZ587312A patent/NZ587312A/en not_active IP Right Cessation
- 2009-02-13 SI SI200930714T patent/SI2254598T1/sl unknown
- 2009-02-13 CN CN2009801102033A patent/CN101977628A/zh active Pending
- 2009-02-13 US US12/867,073 patent/US20110059947A1/en not_active Abandoned
-
2010
- 2010-08-03 IL IL207389A patent/IL207389A0/en unknown
- 2010-08-23 ZA ZA2010/05999A patent/ZA201005999B/en unknown
- 2010-09-09 EC EC2010010471A patent/ECSP10010471A/es unknown
- 2010-09-10 CO CO10112124A patent/CO6290706A2/es not_active Application Discontinuation
-
2013
- 2013-10-10 CY CY20131100896T patent/CY1114492T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2010008875A (es) | 2010-08-31 |
| RU2481123C2 (ru) | 2013-05-10 |
| PL2254598T3 (pl) | 2013-12-31 |
| WO2009102962A2 (en) | 2009-08-20 |
| RS52941B (sr) | 2014-02-28 |
| RU2010137787A (ru) | 2012-03-20 |
| EP2254598A2 (en) | 2010-12-01 |
| ES2430622T3 (es) | 2013-11-21 |
| CA2715268A1 (en) | 2009-08-20 |
| HRP20130749T1 (en) | 2013-10-11 |
| CO6290706A2 (es) | 2011-06-20 |
| SG188144A1 (en) | 2013-03-28 |
| BRPI0907570A2 (pt) | 2019-09-24 |
| JP2011511845A (ja) | 2011-04-14 |
| IL207389A0 (en) | 2010-12-30 |
| CN103143023A (zh) | 2013-06-12 |
| US20110059947A1 (en) | 2011-03-10 |
| WO2009102962A3 (en) | 2009-10-08 |
| HK1147954A1 (en) | 2011-08-26 |
| ZA201005999B (en) | 2011-05-25 |
| EP2633868A1 (en) | 2013-09-04 |
| NZ587312A (en) | 2011-12-22 |
| CN101977628A (zh) | 2011-02-16 |
| AU2009214625A1 (en) | 2009-08-20 |
| DK2254598T3 (da) | 2013-07-29 |
| PT2254598E (pt) | 2013-10-16 |
| KR20100113163A (ko) | 2010-10-20 |
| SI2254598T1 (sl) | 2013-10-30 |
| ECSP10010471A (es) | 2010-10-30 |
| EP2254598B1 (en) | 2013-07-10 |
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