CY1112970T1 - Μεθοδος παρασκευης κρυσταλλικης κικλεζονιδης με καθορισμενο μεγεθος σωματιδιων - Google Patents

Μεθοδος παρασκευης κρυσταλλικης κικλεζονιδης με καθορισμενο μεγεθος σωματιδιων

Info

Publication number
CY1112970T1
CY1112970T1 CY20121100425T CY121100425T CY1112970T1 CY 1112970 T1 CY1112970 T1 CY 1112970T1 CY 20121100425 T CY20121100425 T CY 20121100425T CY 121100425 T CY121100425 T CY 121100425T CY 1112970 T1 CY1112970 T1 CY 1112970T1
Authority
CY
Cyprus
Prior art keywords
particle size
cyclezonide
crystal
preparation
specified particle
Prior art date
Application number
CY20121100425T
Other languages
English (en)
Inventor
Beate Schmidt
Klaus Eistetter
Stefan Kaupp
Ernst Sturm
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33099298&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1112970(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of CY1112970T1 publication Critical patent/CY1112970T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F21/00—Dissolving

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Η εφεύρεση σχετίζεται με μια νέα μέθοδο παρασκευής κρυσταλλικής κικλεζονίδης με επωφελές μέγεθος σωματιδίων και με τη χρήση για την παραγωγή φαρμακευτικών παρασκευασμάτων, συγκεκριμένα για τοπική χρήση. Η κρυσταλλική κικλεζονίδη η οποία λαμβάνεται με τη νέα μέθοδο έχει επωφελείς αεροδυναμικές ιδιότητες και μπορεί να επεξεργαστεί περαιτέρω για εισπνεόμενα ή ρινικώς χορηγούμενα φαρμακευτικά παρασκευάσματα χωρίς περαιτέρω μηχανική μικρολειοτρίβηση.
CY20121100425T 2003-03-27 2012-05-08 Μεθοδος παρασκευης κρυσταλλικης κικλεζονιδης με καθορισμενο μεγεθος σωματιδιων CY1112970T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03007007 2003-03-27
DE10314097 2003-03-27
EP04723609A EP1611150B1 (en) 2003-03-27 2004-03-26 Process for preparing crystalline ciclesonide with defined particle size

Publications (1)

Publication Number Publication Date
CY1112970T1 true CY1112970T1 (el) 2016-04-13

Family

ID=33099298

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100425T CY1112970T1 (el) 2003-03-27 2012-05-08 Μεθοδος παρασκευης κρυσταλλικης κικλεζονιδης με καθορισμενο μεγεθος σωματιδιων

Country Status (28)

Country Link
US (1) US9422327B2 (el)
EP (1) EP1611150B1 (el)
JP (1) JP4746535B2 (el)
KR (1) KR101102709B1 (el)
AR (1) AR043579A1 (el)
AT (1) ATE546459T1 (el)
AU (1) AU2004224092B2 (el)
BR (1) BRPI0408569B1 (el)
CA (1) CA2519752C (el)
CL (1) CL2004000636A1 (el)
CY (1) CY1112970T1 (el)
DK (1) DK1611150T3 (el)
EA (1) EA011157B1 (el)
ES (1) ES2382928T3 (el)
HK (1) HK1088905A1 (el)
HR (1) HRP20050917B1 (el)
IL (1) IL170746A (el)
MX (1) MXPA05010041A (el)
MY (1) MY143936A (el)
NO (1) NO331984B1 (el)
NZ (1) NZ542827A (el)
PE (1) PE20050388A1 (el)
PL (1) PL1611150T3 (el)
PT (1) PT1611150E (el)
RS (1) RS52549B (el)
SI (1) SI1611150T1 (el)
TW (1) TWI328589B (el)
WO (1) WO2004085460A1 (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20050941A1 (es) 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
CA2622640A1 (en) * 2005-11-02 2007-05-18 Sicor Inc. Improved process for the preparation of ciclesonide
EP1904514A2 (en) * 2006-02-08 2008-04-02 Sicor, Inc. Crystalline forms of ciclesonide
WO2008015696A2 (en) * 2006-05-23 2008-02-07 Cadila Healthcare Limited Process for preparing ciclesonide
WO2008062450A2 (en) * 2006-09-18 2008-05-29 Cadila Healthcare Limited Crystalline polymorphs of ciclesonide
WO2008035066A2 (en) * 2006-09-19 2008-03-27 Cipla Limited Processes for the preparation of ciclesonide and its crystal form
CA2714653A1 (en) * 2008-03-13 2009-09-17 Farmabios S.P.A. Process for the preparation of pregnane derivatives
IT1397499B1 (it) * 2009-01-09 2013-01-16 Farmabios Spa Processo per la preparazione di ciclesonide
US20100120733A1 (en) * 2008-11-07 2010-05-13 Auspex Pharmaceuticals, Inc. Steroid modulators of glucocorticoid receptor
US9109005B2 (en) 2012-02-23 2015-08-18 Boehringer Ingelheim International Gmbh Method for manufacturing of ciclesonide
WO2014007772A2 (en) 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising glucose anhydrous
US20150224197A1 (en) 2012-07-05 2015-08-13 Arven Ilac Sanayi Ve Ticaret A.S. Inhalation compositions
WO2014007770A2 (en) 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising corticosteroid and sorbitol
CA3025377A1 (en) 2016-06-02 2017-12-07 Abbvie Inc. Glucocorticoid receptor agonist and immunoconjugates thereof
RU2020117698A (ru) 2017-12-01 2022-01-04 Эббви Инк. Агонист глюкокортикоидного рецептора и его иммуноконъюгаты

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8328929D0 (en) 1983-10-29 1983-11-30 Sterwin Ag Steroid compounds
WO1990003782A2 (en) 1988-10-05 1990-04-19 The Upjohn Company Finely divided solid crystalline powders via precipitation into an anti-solvent
DE69012458T3 (de) 1989-05-31 2000-01-20 Fisons Plc Medikament und Inhalationsvorrichtung dafür.
GR1001529B (el) 1990-09-07 1994-03-31 Elmuquimica Farm Sl Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
FR2668945B1 (fr) 1990-11-12 1993-02-19 Theramex Nouveau procede de cristallisation des substances organiques et les composes ainsi obtenus.
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
GB9213874D0 (en) 1992-06-30 1992-08-12 Fisons Plc Process to novel medicament form
GB9306703D0 (en) 1993-03-31 1993-05-26 Fisons Plc Inhalation device
AU683463B2 (en) 1993-04-02 1997-11-13 Astrazeneca Ab New prednisolone derivates
IL111194A (en) 1993-10-08 1998-02-08 Fisons Plc Process for the production of drug patramulations
EP0749438B1 (de) 1994-03-09 2000-12-13 Byk Gulden Lomberg Chemische Fabrik GmbH Neue silylverbindungen und ihre verwendung
DE19541689A1 (de) 1994-11-14 1996-05-15 Byk Gulden Lomberg Chem Fab Kombinationsarzneimittel
DE19635498A1 (de) 1996-09-03 1998-03-26 Byk Gulden Lomberg Chem Fab Verfahren zur Epimerenanreicherung
US6120752A (en) 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
GB9722285D0 (en) 1997-10-23 1997-12-17 Rhone Poulenc Rorer Ltd Inhalation device
US6264923B1 (en) 1998-05-13 2001-07-24 3M Innovative Properties Company Medicinal aerosol formulation of ciclesonide and related compounds
ES2234266T3 (es) * 1998-07-24 2005-06-16 Jago Research Ag Formulaciones medicas para aerosoles.
GB9828721D0 (en) 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
CA2376818A1 (en) 1999-06-25 2001-01-04 Cognis Deutschland Gmbh & Co. Kg Use of nanoscale sterols and sterol esters
AR026072A1 (es) 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa
AR026073A1 (es) 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
US7468433B2 (en) 2000-11-10 2008-12-23 Nycomed Gmbh Process for the production of 16,17-[(cyclohexylmethylen)bis(oxy)]-11,21-dihydroxy-pregna-1,4-dien-3,20-dion or its 21-isobutyrat by transketalisation

Also Published As

Publication number Publication date
EP1611150B1 (en) 2012-02-22
AU2004224092A1 (en) 2004-10-07
DK1611150T3 (da) 2012-05-14
NO331984B1 (no) 2012-05-21
ATE546459T1 (de) 2012-03-15
WO2004085460A1 (en) 2004-10-07
WO2004085460A8 (en) 2007-03-15
CL2004000636A1 (es) 2005-02-04
US9422327B2 (en) 2016-08-23
PL1611150T3 (pl) 2012-07-31
ES2382928T3 (es) 2012-06-14
EA200501391A1 (ru) 2006-06-30
RS52549B (en) 2013-04-30
HRP20050917A2 (en) 2006-12-31
PE20050388A1 (es) 2005-05-30
BRPI0408569B1 (pt) 2017-08-29
RS20050704A (en) 2007-06-04
BRPI0408569A (pt) 2006-03-21
MXPA05010041A (es) 2005-11-17
HRP20050917B1 (hr) 2014-02-14
EP1611150A1 (en) 2006-01-04
IL170746A0 (en) 2009-02-11
TW200418519A (en) 2004-10-01
PT1611150E (pt) 2012-05-07
AU2004224092B2 (en) 2010-03-04
AR043579A1 (es) 2005-08-03
NO20054835L (no) 2005-10-19
KR20050114250A (ko) 2005-12-05
CA2519752C (en) 2012-05-29
JP4746535B2 (ja) 2011-08-10
IL170746A (en) 2012-06-28
SI1611150T1 (sl) 2012-06-29
NZ542827A (en) 2008-02-29
JP2006521332A (ja) 2006-09-21
KR101102709B1 (ko) 2012-01-05
CA2519752A1 (en) 2004-10-07
HK1088905A1 (en) 2006-11-17
MY143936A (en) 2011-07-29
US20060128954A1 (en) 2006-06-15
EA011157B1 (ru) 2009-02-27
TWI328589B (en) 2010-08-11

Similar Documents

Publication Publication Date Title
CY1112970T1 (el) Μεθοδος παρασκευης κρυσταλλικης κικλεζονιδης με καθορισμενο μεγεθος σωματιδιων
UY27755A1 (es) Nuevas composiciones farmacéuticas basadas en anticolinérgicos e inhibidores.
CY1106430T1 (el) Φαρμακα για εισπνοη που πepιλαμβανουν βηταμιμητικα και αντιχολινepγικο
CY1114157T1 (el) Αλατα του τιοτροπιου, μεθοδος για την παραγωγη τους και φαρμακευτικα σκευασματα που τα περιεχουν
CY1118720T1 (el) Ορθωτικη διαταξη
BRPI0608297A2 (pt) composições de lipossomos
CA2633594C (en) Means and methods for the treatment of tumorous diseases
WO2009060281A3 (en) Immune stimulatory oligoribonucleotide analogs containing modified oligophosphate moieties
BRPI0513819A (pt) inibidores de hsp90
CY1106056T1 (el) Παραγωγα 2-αμινο-2-αλκυλ-5-επτενοϊκου και επτυνοϊκου οξεος χρησιμα σαν αναστολεις συνθασης νιτρικου οξειδιου
WO2006138608A3 (en) Pharmaceutical compositions and use thereof
NZ590143A (en) Anti-inflammatory proteins and methods of preparation and use thereof
EA200401515A1 (ru) Новые фармацевтические композиции, содержащие флибансерин в полиморфной модификации а
SE0300098D0 (sv) Use of cyclin D1 inhibitors
SG149876A1 (en) Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same
WO2006059323A3 (en) Production of proteins
ATE483796T1 (de) Impfstoff gegen die chinaseuche (rhd) bei kaninchen
EA200401303A1 (ru) Лекарственные средства, содержащие стероиды и новое антихолинергическое средство
BRPI0409175A (pt) preparação farmacêutica oral para antagonistas de bombeamento de próton
AR036518A1 (es) Nuevos medicamentos para la inhalacion
DE602004019096D1 (de) Medikamente zur inhalation mit betamimetika und einem anticholinergikum
UY26990A1 (es) Nuevas composiciones de medicamentos
SE0101386D0 (sv) New compounds
WO2004083390A3 (en) Virulent systemic feline calicivirus
EA200401082A1 (ru) Новые соединения бензоиндолина, способ их получения и фармацевтические композиции, которые их содержат