CY1111970T1 - Μεθοδοι για την ανιχνευση της νοσου αλτσχαϊμερ - Google Patents

Μεθοδοι για την ανιχνευση της νοσου αλτσχαϊμερ

Info

Publication number
CY1111970T1
CY1111970T1 CY20111101024T CY111101024T CY1111970T1 CY 1111970 T1 CY1111970 T1 CY 1111970T1 CY 20111101024 T CY20111101024 T CY 20111101024T CY 111101024 T CY111101024 T CY 111101024T CY 1111970 T1 CY1111970 T1 CY 1111970T1
Authority
CY
Cyprus
Prior art keywords
disease
methods
altscheimer
detection
alzheimer
Prior art date
Application number
CY20111101024T
Other languages
English (en)
Inventor
Sandrine Mace
Sylvain Ricard
Emmanuelle Cousin
Laurent Pradier
Jesus Benavides
Jean-François Deleuze
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of CY1111970T1 publication Critical patent/CY1111970T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Μέθοδοι για τη διάγνωση ή την πρόγνωση της νόσου Αλτσχάϊμερ σε ένα άτομο. Η εν λόγω μέθοδος περιλαμβάνει τουλάχιστον ένα στάδιο ανίχνευσης της παρουσίας ή της απουσίας του πολυμορφισμού rs908832 του γονιδίου ABACA2. Η παρουσία του ελάσσονος αλληλίου του πολυμορφισμού rs908832 του γονιδίου ABACA2 υποδεικνύει ότι το υποκείμενο μπορεί να έχει προσβληθεί από τη νόσο Αλτσχάϊμερ ή ακόμη να παρουσιάζει ένα αυξημένο κίνδυνο να αναπτύξει τη νόσο Αλτσχάϊμερ.
CY20111101024T 2003-06-20 2011-10-27 Μεθοδοι για την ανιχνευση της νοσου αλτσχαϊμερ CY1111970T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0307501A FR2856409B1 (fr) 2003-06-20 2003-06-20 Methodes de detection de la maladie d'alzheimer
EP04767370A EP1639139B1 (fr) 2003-06-20 2004-06-17 Methodes de detection de la maladie d'alzheimer

Publications (1)

Publication Number Publication Date
CY1111970T1 true CY1111970T1 (el) 2015-11-04

Family

ID=33484616

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111101024T CY1111970T1 (el) 2003-06-20 2011-10-27 Μεθοδοι για την ανιχνευση της νοσου αλτσχαϊμερ

Country Status (25)

Country Link
EP (1) EP1639139B1 (el)
JP (1) JP4691491B2 (el)
KR (1) KR101170651B1 (el)
CN (1) CN1809645B (el)
AR (1) AR044492A1 (el)
AT (1) ATE518005T1 (el)
AU (1) AU2004249919B2 (el)
BR (1) BRPI0411658A (el)
CA (1) CA2529633C (el)
CY (1) CY1111970T1 (el)
DK (1) DK1639139T3 (el)
ES (1) ES2370491T3 (el)
FR (1) FR2856409B1 (el)
HK (1) HK1090392A1 (el)
HR (1) HRP20110778T1 (el)
IL (1) IL172690A0 (el)
MX (1) MXPA05012800A (el)
NO (1) NO20060257L (el)
PL (1) PL1639139T3 (el)
PT (1) PT1639139E (el)
RU (2) RU2483108C2 (el)
SI (1) SI1639139T1 (el)
TW (1) TWI352738B (el)
WO (1) WO2004113568A2 (el)
ZA (1) ZA200509945B (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103013989A (zh) * 2011-09-23 2013-04-03 深圳北京大学香港科技大学医学中心 与老年痴呆症发病相关的细胞周期依赖性激酶5的单核苷酸多态性位点
GB201212084D0 (en) * 2012-07-06 2012-08-22 Randox Lab Ltd Tropomyosin isoforms related to alzheimers disease and mild cognitive impairment
CN102768189B (zh) * 2012-07-30 2014-11-19 黄石 一种药物筛选方法
CN104313144B (zh) * 2014-10-16 2017-02-01 卫生部北京医院 一种检测阿尔茨海默病易感性的试剂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853995A (en) * 1997-01-07 1998-12-29 Research Development Foundation Large scale genotyping of diseases and a diagnostic test for spinocerebellar ataxia type 6
WO2001014414A2 (en) * 1999-08-20 2001-03-01 Activepass Pharmaceuticals, Inc. Human abc2 transporter and uses thereof
EP1304922A2 (en) * 2000-07-20 2003-05-02 Cephalon, Inc. Gene-targeted non-human mammal with human fad presenilin mutation and generational offspring
JP2004147502A (ja) * 2000-07-26 2004-05-27 Banyu Pharmaceut Co Ltd ヒト及びラットabca2遺伝子
WO2002064781A2 (en) * 2001-02-09 2002-08-22 Active Pass Pharmaceuticals, Inc. Regulation of amyloid precursor protein expression by modification of abc transporter expression or activity
US20050019765A1 (en) * 2001-06-08 2005-01-27 Wellington Cheryl L Methods for treating disorders of the nervous and reproductive systems

Also Published As

Publication number Publication date
SI1639139T1 (sl) 2011-11-30
PT1639139E (pt) 2011-10-24
AU2004249919A1 (en) 2004-12-29
JP2007515151A (ja) 2007-06-14
RU2006101561A (ru) 2006-06-10
WO2004113568A2 (fr) 2004-12-29
RU2483108C2 (ru) 2013-05-27
EP1639139B1 (fr) 2011-07-27
HRP20110778T1 (hr) 2011-11-30
PL1639139T3 (pl) 2011-12-30
HK1090392A1 (en) 2006-12-22
DK1639139T3 (da) 2011-11-21
AR044492A1 (es) 2005-09-14
TWI352738B (en) 2011-11-21
IL172690A0 (en) 2006-04-10
TW200517502A (en) 2005-06-01
ES2370491T3 (es) 2011-12-16
CN1809645B (zh) 2013-11-20
CA2529633A1 (fr) 2004-12-29
FR2856409B1 (fr) 2007-08-31
ATE518005T1 (de) 2011-08-15
MXPA05012800A (es) 2006-05-17
AU2004249919B2 (en) 2009-08-13
BRPI0411658A (pt) 2006-08-08
FR2856409A1 (fr) 2004-12-24
EP1639139A2 (fr) 2006-03-29
WO2004113568A3 (fr) 2005-05-06
KR20060029232A (ko) 2006-04-05
NO20060257L (no) 2006-01-18
CN1809645A (zh) 2006-07-26
RU2009104533A (ru) 2010-08-20
KR101170651B1 (ko) 2012-08-03
ZA200509945B (en) 2007-03-28
JP4691491B2 (ja) 2011-06-01
CA2529633C (fr) 2014-08-05
RU2380423C2 (ru) 2010-01-27

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