CY1111503T1 - Υδατικο διαλυμα οξανεξιδινης, μεθοδος παρασκευης του ιδιου, και απολυμαντικο - Google Patents

Υδατικο διαλυμα οξανεξιδινης, μεθοδος παρασκευης του ιδιου, και απολυμαντικο

Info

Publication number
CY1111503T1
CY1111503T1 CY20111100448T CY111100448T CY1111503T1 CY 1111503 T1 CY1111503 T1 CY 1111503T1 CY 20111100448 T CY20111100448 T CY 20111100448T CY 111100448 T CY111100448 T CY 111100448T CY 1111503 T1 CY1111503 T1 CY 1111503T1
Authority
CY
Cyprus
Prior art keywords
disinfectant
axanexidine
axide
solution
property method
Prior art date
Application number
CY20111100448T
Other languages
English (en)
Inventor
Kazuyoshi Miyata
Yasuhide Inoue
Akifumi Hagi
Motoya Kikuchi
Hitoshi Ohno
Kinji Hashimoto
Kinue Ohguro
Tetsuya Sato
Hidetsugu Tsubouchi
Hiroshi Ishikawa
Takashi Okamura
Koushi Iwata
Original Assignee
Otsuka Pharmaceutical Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co., Ltd filed Critical Otsuka Pharmaceutical Co., Ltd
Publication of CY1111503T1 publication Critical patent/CY1111503T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Environmental Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Η παρούσα εφεύρεση παρέχει ένα απολυμαντικό που περιέχει ολανεξιδίνη σε συγκέντρωση που επαρκεί για να εμφανίσει αποτελεσματική βακτηριοκτόνο δράση, και που δεν έχει σχεδόν καμία παράπλευρη δράση όπως δερματικό ερεθισμό. Συγκεκριμένα, η παρούσα εφεύρεση παρέχει ένα απολυμαντικό που περιέχει ένα υδατικό διάλυμα που περιέχει ολανεξιδίνη και τουλάχιστον ισομοριακή ποσότητα γλουκονικού οξέος, και ουσιαστικά δεν περιέχει ούτε άλλο οξύ εκτός από το γλουκονικό οξύ ούτε άλας άλλου οξέος εκτός από το γλουκονικό οξύ.
CY20111100448T 2003-05-28 2011-05-09 Υδατικο διαλυμα οξανεξιδινης, μεθοδος παρασκευης του ιδιου, και απολυμαντικο CY1111503T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003150846 2003-05-28
EP04734736A EP1634589B9 (en) 2003-05-28 2004-05-25 Aqueous olanexidine solution, method of preparing the same, and disinfectant

Publications (1)

Publication Number Publication Date
CY1111503T1 true CY1111503T1 (el) 2015-10-07

Family

ID=33487195

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100448T CY1111503T1 (el) 2003-05-28 2011-05-09 Υδατικο διαλυμα οξανεξιδινης, μεθοδος παρασκευης του ιδιου, και απολυμαντικο

Country Status (22)

Country Link
US (3) US7829518B2 (el)
EP (1) EP1634589B9 (el)
KR (1) KR101017334B1 (el)
CN (2) CN1794983B (el)
AR (2) AR044563A1 (el)
AT (1) ATE499095T1 (el)
AU (1) AU2004243183B2 (el)
BR (1) BRPI0410851B8 (el)
CA (1) CA2526570C (el)
CY (1) CY1111503T1 (el)
DE (1) DE602004031523D1 (el)
DK (1) DK1634589T3 (el)
ES (1) ES2358740T3 (el)
HK (2) HK1086200A1 (el)
MX (1) MXPA05012761A (el)
MY (2) MY144306A (el)
PL (1) PL1634589T3 (el)
PT (1) PT1634589E (el)
RU (1) RU2334508C2 (el)
SI (1) SI1634589T1 (el)
TW (2) TWI400038B (el)
WO (1) WO2004105745A1 (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101506152B (zh) 2006-08-30 2012-11-21 大塚制药株式会社 1-(3,4-二氯苄基)-5-辛基双胍或其盐的制备方法
AU2009249584B2 (en) 2008-05-19 2014-03-20 Otsuka America Pharmaceutical, Inc. Method and apparatus for preparing a solution of a shear sensitive material
JP5383281B2 (ja) 2009-03-30 2014-01-08 花王株式会社 農薬含有組成物
US10888535B2 (en) * 2015-12-07 2021-01-12 Otsuka Pharmaceutical Factory, Inc. Skin disinfectant composition
CA3058592C (en) * 2017-04-19 2021-11-09 Otsuka Pharmaceutical Factory, Inc. Olanexidine as anti-inflammatory agent
CN107668062B (zh) * 2017-10-27 2021-03-09 金英花 基于透明质酸的奥兰西丁水溶液及其制备方法和应用
CN107646862B (zh) * 2017-10-27 2021-05-07 江苏食品药品职业技术学院 基于抗坏血酸的奥兰西丁水溶液及其制备方法和应用
CA3102757A1 (en) * 2018-07-18 2020-01-23 Otsuka Pharmaceutical Factory, Inc. Disinfectant composition

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB815925A (en) * 1956-06-06 1959-07-01 Ici Ltd New biguanide salts
US4734222A (en) * 1986-04-03 1988-03-29 Ciba-Geigy Corporation Composition and method for cleaning soft and hard contact lenses
DE3816734A1 (de) * 1988-05-17 1989-11-30 Henkel Kgaa Verfahren zur reinigung und desinfektion von hitze- und korrosionsempfindlichen medizinischen geraeten, insbesondere von endoskopen und mittel zur durchfuehrung des verfahrens
JP3308980B2 (ja) 1991-03-15 2002-07-29 東燃ゼネラル石油株式会社 末端修飾ポリプロピレン及びその製法
CA2064664C (en) * 1991-04-05 2000-01-11 Hiroshi Ishikawa Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
JP2662343B2 (ja) * 1991-06-19 1997-10-08 大塚製薬株式会社 モノビグアナイド誘導体とこの誘導体を含有した消毒薬
JP3118050B2 (ja) * 1991-12-12 2000-12-18 三菱マテリアル株式会社 殺菌剤
JP3118051B2 (ja) * 1991-12-12 2000-12-18 三菱マテリアル株式会社 殺菌剤
GB2262283B (en) * 1991-12-12 1996-01-17 Mitsubishi Materials Corp Biguanide disinfectants
JP3493692B2 (ja) * 1993-09-09 2004-02-03 三菱マテリアル株式会社 ビスビグアナイド系化合物およびそれを含む殺菌剤
US5977034A (en) 1994-08-19 1999-11-02 Lifenet Research Foundation Composition for cleaning bones
US5997759A (en) * 1997-06-09 1999-12-07 The Procter & Gamble Company Uncomplexed cyclodextrin compositions for odor control
CO5040174A1 (es) * 1997-12-12 2001-05-29 Colgate Palmolive Co Composiciones antimicrobianas para multiples propositos en microemulsion que contienen un tensioactivo cationico
JP3883739B2 (ja) * 1998-05-22 2007-02-21 株式会社メニコン コンタクトレンズ用殺菌液
AU758625B2 (en) 1998-08-20 2003-03-27 Ecolab Inc. The treatment of meat products
JP3636611B2 (ja) 1999-03-19 2005-04-06 日華化学株式会社 殺菌消毒剤組成物
US5998358A (en) * 1999-03-23 1999-12-07 Ecolab Inc. Antimicrobial acid cleaner for use on organic or food soil

Also Published As

Publication number Publication date
US20070041866A1 (en) 2007-02-22
CN102715184B (zh) 2016-04-27
EP1634589A4 (en) 2007-11-07
BRPI0410851B1 (pt) 2016-06-07
HK1086200A1 (en) 2006-09-15
MXPA05012761A (es) 2006-05-17
HK1176817A1 (zh) 2013-08-09
EP1634589B9 (en) 2011-08-31
AR095681A2 (es) 2015-11-04
CA2526570A1 (en) 2004-12-09
PL1634589T3 (pl) 2011-07-29
KR20060021868A (ko) 2006-03-08
KR101017334B1 (ko) 2011-02-28
BRPI0410851B8 (pt) 2023-04-25
DE602004031523D1 (de) 2011-04-07
EP1634589A1 (en) 2006-03-15
US7829518B2 (en) 2010-11-09
MY144306A (en) 2011-08-29
EP1634589B1 (en) 2011-02-23
TWI400038B (zh) 2013-07-01
CN1794983A (zh) 2006-06-28
CA2526570C (en) 2012-09-11
CN1794983B (zh) 2012-07-18
US20060189500A1 (en) 2006-08-24
US20100331423A1 (en) 2010-12-30
DK1634589T3 (da) 2011-04-18
RU2334508C2 (ru) 2008-09-27
SI1634589T1 (sl) 2011-05-31
AU2004243183B2 (en) 2009-08-06
ATE499095T1 (de) 2011-03-15
US7825080B2 (en) 2010-11-02
AU2004243183A1 (en) 2004-12-09
MY144204A (en) 2011-08-15
TW201141384A (en) 2011-12-01
ES2358740T3 (es) 2011-05-13
TW200427661A (en) 2004-12-16
PT1634589E (pt) 2011-03-24
CN102715184A (zh) 2012-10-10
TWI355930B (en) 2012-01-11
WO2004105745A1 (ja) 2004-12-09
AR044563A1 (es) 2005-09-21
US8334248B2 (en) 2012-12-18
BRPI0410851A (pt) 2006-07-04
RU2005141134A (ru) 2006-06-10

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