CY1111369T1 - Φαρμακευτικη συνθεση που περιλαμβανει 3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινολη και παρακεταμολη - Google Patents

Φαρμακευτικη συνθεση που περιλαμβανει 3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινολη και παρακεταμολη

Info

Publication number
CY1111369T1
CY1111369T1 CY20111100353T CY111100353T CY1111369T1 CY 1111369 T1 CY1111369 T1 CY 1111369T1 CY 20111100353 T CY20111100353 T CY 20111100353T CY 111100353 T CY111100353 T CY 111100353T CY 1111369 T1 CY1111369 T1 CY 1111369T1
Authority
CY
Cyprus
Prior art keywords
phenol
propyl
ethyl
methyl
paraketamol
Prior art date
Application number
CY20111100353T
Other languages
English (en)
Inventor
Petra Bloms-Funke
Klaus Schiene
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37025148&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1111369(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of CY1111369T1 publication Critical patent/CY1111369T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αφορά μια σύνθεση που περιέχει ως συστατικά (α) την ένωση 3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινόλη και (β) Παρακεταμόλη ή ένα παράγωγο αυτής, ένα φαρμακευτικό σκεύασμα και μια μορφή δόσης που περιέχει την αναφερθείσα σύνθεση, καθώς και μια μέθοδο για την αντιμετώπιση του πόνου, π.χ. του χρόνιου ή οξέος πόνου, η οποία χαρακτηρίζεται από το ότι τα συστατικά (α) και (β) χορηγούνται ταυτόχρονα ή διαδοχικά σε ένα θηλαστικό, όπου το συστατικό (α) μπορεί να χορηγηθεί πριν ή μετά το συστατικό (β) και όπου τα συστατικά (α) ή (β) χορηγούνται στο θηλαστικό είτε μέσω της ίδιας είτε μέσω διαφορετικής οδού χορήγησης.
CY20111100353T 2006-04-28 2011-04-05 Φαρμακευτικη συνθεση που περιλαμβανει 3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινολη και παρακεταμολη CY1111369T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06008851 2006-04-28
EP07724562A EP2012764B1 (en) 2006-04-28 2007-04-25 Pharmaceutical combination comprising 3-(3-dimethylamino-1-ethyl-2-methyl-propyl) -phenol and paracetamol

Publications (1)

Publication Number Publication Date
CY1111369T1 true CY1111369T1 (el) 2015-08-05

Family

ID=37025148

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100353T CY1111369T1 (el) 2006-04-28 2011-04-05 Φαρμακευτικη συνθεση που περιλαμβανει 3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινολη και παρακεταμολη

Country Status (25)

Country Link
EP (1) EP2012764B1 (el)
JP (2) JP5496653B2 (el)
KR (1) KR101396166B1 (el)
CN (1) CN101431990B (el)
AT (1) ATE494889T1 (el)
AU (1) AU2007247481B2 (el)
BR (1) BRPI0710682B8 (el)
CA (1) CA2650423C (el)
CY (1) CY1111369T1 (el)
DE (1) DE602007011913D1 (el)
DK (1) DK2012764T3 (el)
EC (2) ECSP088793A (el)
ES (1) ES2356093T3 (el)
HK (1) HK1127289A1 (el)
HR (1) HRP20110076T1 (el)
IL (1) IL194883A (el)
MX (1) MX2008013779A (el)
NO (2) NO341602B1 (el)
NZ (1) NZ571442A (el)
PL (1) PL2012764T3 (el)
PT (1) PT2012764E (el)
RU (1) RU2442576C2 (el)
SI (1) SI2012764T1 (el)
WO (1) WO2007128413A1 (el)
ZA (1) ZA200810124B (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007012165A1 (de) 2007-03-12 2008-09-18 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes
KR101972299B1 (ko) * 2007-11-23 2019-08-16 그뤼넨탈 게엠베하 타펜타돌 조성물
PT2582366E (pt) 2010-06-15 2016-01-26 Gruenenthal Gmbh Combinação terapêutica para o tratamento da dor
CN107088226A (zh) 2011-03-04 2017-08-25 格吕伦塔尔有限公司 他喷他多的胃肠外给药
US9446008B2 (en) 2011-03-04 2016-09-20 Gruenenthal Gmbh Semisolid aqueous pharmaceutical composition containing tapentadol
RS59491B1 (sr) 2011-03-04 2019-12-31 Gruenenthal Gmbh Vodena farmaceutska formulacija tapentadola za oralnu primenu
US9855286B2 (en) 2012-05-18 2018-01-02 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
US20130310385A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
US20130310435A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol
US9320729B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
EP2808319A1 (en) 2013-05-31 2014-12-03 Arevipharma GmbH 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex
JP6923447B2 (ja) 2015-03-27 2021-08-18 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング タペンタドールの非経口投与のための安定な製剤
AU2017329964B2 (en) 2016-09-23 2022-10-06 Grünenthal GmbH Stable formulation for parenteral administration of Tapentadol
WO2018153947A1 (en) 2017-02-23 2018-08-30 Grünenthal GmbH Tapentadol as local anesthetic

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
PE20030527A1 (es) * 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
LT1562567T (lt) * 2002-11-22 2017-08-25 Grünenthal GmbH Pasirinktų analgetikų ir cox-ii slopiklių derinys

Also Published As

Publication number Publication date
CN101431990B (zh) 2011-08-03
KR101396166B1 (ko) 2014-05-27
JP2009535313A (ja) 2009-10-01
ES2356093T3 (es) 2011-04-04
BRPI0710682B8 (pt) 2021-05-25
IL194883A (en) 2012-10-31
PT2012764E (pt) 2011-02-02
EP2012764B1 (en) 2011-01-12
HRP20110076T1 (hr) 2011-02-28
NO20084542L (no) 2008-10-28
ZA200810124B (en) 2009-08-26
JP5496653B2 (ja) 2014-05-21
EP2012764A1 (en) 2009-01-14
AU2007247481A1 (en) 2007-11-15
CA2650423A1 (en) 2007-11-15
RU2008146816A (ru) 2010-06-10
PL2012764T3 (pl) 2011-04-29
MX2008013779A (es) 2008-11-14
NO341602B1 (no) 2017-12-11
ATE494889T1 (de) 2011-01-15
CN101431990A (zh) 2009-05-13
KR20090006219A (ko) 2009-01-14
AU2007247481B2 (en) 2013-02-14
DE602007011913D1 (de) 2011-02-24
HK1127289A1 (en) 2009-09-25
NO343505B1 (no) 2019-03-25
JP2013213045A (ja) 2013-10-17
ECSP088793A (es) 2008-11-27
BRPI0710682B1 (pt) 2020-09-24
BRPI0710682A2 (pt) 2011-08-23
NO20171831A1 (no) 2008-10-28
SI2012764T1 (sl) 2011-03-31
IL194883A0 (en) 2009-08-03
DK2012764T3 (da) 2011-02-28
ECSP17000643A (es) 2018-06-30
WO2007128413A1 (en) 2007-11-15
RU2442576C2 (ru) 2012-02-20
NZ571442A (en) 2011-09-30
CA2650423C (en) 2014-08-12

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