CY1109881T1 - Νεοαγγειακα-συγκεκριμενα πεπτιδια - Google Patents

Νεοαγγειακα-συγκεκριμενα πεπτιδια

Info

Publication number
CY1109881T1
CY1109881T1 CY20101100192T CY101100192T CY1109881T1 CY 1109881 T1 CY1109881 T1 CY 1109881T1 CY 20101100192 T CY20101100192 T CY 20101100192T CY 101100192 T CY101100192 T CY 101100192T CY 1109881 T1 CY1109881 T1 CY 1109881T1
Authority
CY
Cyprus
Prior art keywords
cancer
peptides
neo
vegetable
specific peptides
Prior art date
Application number
CY20101100192T
Other languages
English (en)
Inventor
Naoto Oku
Koichi Ogino
Dai Ishikawa
Michinori Tanaka
Takao Taki
Original Assignee
Otsuka Pharmaceutical Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co., Ltd filed Critical Otsuka Pharmaceutical Co., Ltd
Publication of CY1109881T1 publication Critical patent/CY1109881T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Νεοαγγειακά-συγκεκριμένα πεπτίδια τα οποία συμπεριλαμβάνουν, για παράδειγμα, πεπτίδια έχοντας τις αλληλουχίες αμινοξέων που αναπαρίστανται μέσω των ΑΛΛΗΛΟΥΧΙΩΝ ΑΡ. ΤΑΥΤΟΤΗΤΑΣ: 1 έως 17 και των δενδριμερών εξ αυτών. Αυτά τα πεπτίδια είναι εφαρμόσιμα σε παρασκευάσματα DDS όπου μπορούν να απελευθερωθούν φάρμακα εκλεκτικώς για να στοχεύσουν ιστούς καρκίνων. Τοιουτοτρόπως αυτά τα πεπτίδια είναι χρήσιμα ως διαγνωστικά για τον καρκίνο, γιατρικά για τον καρκίνο, κλπ., τα οποία συνεισφέρουν στην βελτίωση όσον αφορά τις θεραπευτικές δράσεις στον καρκίνο.
CY20101100192T 1998-10-16 2010-02-25 Νεοαγγειακα-συγκεκριμενα πεπτιδια CY1109881T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP29519898 1998-10-16
JP19470699 1999-07-08
EP99947941A EP1122262B1 (en) 1998-10-16 1999-10-15 Neovascular-specific peptides

Publications (1)

Publication Number Publication Date
CY1109881T1 true CY1109881T1 (el) 2014-09-10

Family

ID=26508673

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100192T CY1109881T1 (el) 1998-10-16 2010-02-25 Νεοαγγειακα-συγκεκριμενα πεπτιδια

Country Status (11)

Country Link
US (1) US6753310B1 (el)
EP (2) EP1122262B1 (el)
JP (1) JP4439120B2 (el)
AT (1) ATE453667T1 (el)
CA (2) CA2622786A1 (el)
CY (1) CY1109881T1 (el)
DE (1) DE69941877D1 (el)
DK (1) DK1122262T3 (el)
ES (1) ES2337321T3 (el)
PT (1) PT1122262E (el)
WO (1) WO2000023476A1 (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1263776A2 (en) * 2000-03-16 2002-12-11 University Of Pittsburgh Peptides targeting specifically tumor-derived endothelial cells
US7071164B2 (en) * 2001-08-16 2006-07-04 Kimberly-Clark Worldwide, Inc. Anti-cancer and wound healing compounds
US7186693B2 (en) * 2001-08-16 2007-03-06 Kimberly - Clark Worldwide, Inc. Metalloproteinase inhibitors for wound healing
US6906036B2 (en) * 2001-08-16 2005-06-14 Kimberly-Clark Worldwide, Inc. Anti-aging and wound healing compounds
KR20050038005A (ko) * 2002-07-18 2005-04-25 헬릭스 바이오파마 코포레이션 암세포 성장의 저해를 위한 우레아제의 사용
US7148194B2 (en) * 2002-12-30 2006-12-12 Kimberly-Clark Worldwide, Inc. Method to increase fibronectin
US7189700B2 (en) * 2003-06-20 2007-03-13 Kimberly-Clark Worldwide, Inc. Anti-chrondrosarcoma compounds
US8440217B1 (en) 2005-06-15 2013-05-14 Mawaheb M. EL-Naggar Method and system with contact lens product for treating and preventing adverse eye conditions
JP5250229B2 (ja) * 2007-09-25 2013-07-31 独立行政法人科学技術振興機構 カーボンナノホーン
WO2009048870A1 (en) * 2007-10-08 2009-04-16 Baylor College Of Medicine Peptide dendrimers: affinity reagents for binding noroviruses
AU2009217237A1 (en) * 2008-02-22 2009-08-27 Inter-K Pty Limited Therapeutic peptides
KR20120102716A (ko) * 2009-11-23 2012-09-18 팔라틴 테크놀로지스 인코포레이티드 멜라노코르틴-1 수용체 특이적 선형 펩티드

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622852A (en) * 1994-10-31 1997-04-22 Washington University Bcl-x/Bcl-2 associated cell death regulator
DE69633186T2 (de) * 1995-11-16 2005-08-18 Novartis Ag Methode zur Identifizierung von Verbindungen die mit RAC Proteine Kinase interagieren
US5922676A (en) * 1996-09-20 1999-07-13 The Burnham Institute Methods of inhibiting cancer by using superfibronectin
CH692507A5 (de) * 1997-04-26 2002-07-15 Peter Prof Dr Sonderegger Neurotrypsin als aktive Verbindung in einem Medikament.
JP4404479B2 (ja) 1997-12-09 2010-01-27 チルドレンズ・メディカル・センター・コーポレイション 血管内皮増殖因子の可溶性インヒビターおよびその使用
JPH11243964A (ja) * 1998-03-03 1999-09-14 Natl Food Res Inst イネオルニチンカルバミルトランスフェラーゼ遺伝子、該遺伝子を含むベクター及び形質転換体
EP0950709A1 (en) * 1998-04-17 1999-10-20 Hoechst Marion Roussel Deutschland GmbH Antisense oligonucleotides for the inhibition of integrin alphaV-subunit expression
AU758074B2 (en) 1998-04-29 2003-03-13 Genesis Research And Development Corporation Limited Polynucleotides isolated from skin cells and methods for their use
AU764277B2 (en) * 1998-05-22 2003-08-14 Abbvie Inc. Peptide antiangiogenic drugs

Also Published As

Publication number Publication date
ATE453667T1 (de) 2010-01-15
DE69941877D1 (de) 2010-02-11
WO2000023476A1 (fr) 2000-04-27
EP1122262A1 (en) 2001-08-08
ES2337321T3 (es) 2010-04-22
DK1122262T3 (da) 2010-04-19
PT1122262E (pt) 2010-01-27
CA2347136A1 (en) 2000-04-27
JP4439120B2 (ja) 2010-03-24
US6753310B1 (en) 2004-06-22
EP1783140A3 (en) 2007-07-11
EP1122262B1 (en) 2009-12-30
CA2622786A1 (en) 2000-04-27
EP1122262A4 (en) 2003-05-21
EP1783140A2 (en) 2007-05-09

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