CY1109652T1 - Lawsonia intracellularis ευρωπαϊκης προελευσεως και εμβολια, διαγνωστικοι παραγοντες και μεθοδοι χρησεως τους - Google Patents

Lawsonia intracellularis ευρωπαϊκης προελευσεως και εμβολια, διαγνωστικοι παραγοντες και μεθοδοι χρησεως τους

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Publication number
CY1109652T1
CY1109652T1 CY20091101223T CY091101223T CY1109652T1 CY 1109652 T1 CY1109652 T1 CY 1109652T1 CY 20091101223 T CY20091101223 T CY 20091101223T CY 091101223 T CY091101223 T CY 091101223T CY 1109652 T1 CY1109652 T1 CY 1109652T1
Authority
CY
Cyprus
Prior art keywords
methods
intracellularis
vaccines
lawsonia intracellularis
european origin
Prior art date
Application number
CY20091101223T
Other languages
English (en)
Inventor
Michael B Roof
Jeremy J Kroll
Jeffrey P Knittel
Original Assignee
Boehringer Ingelheim Vetmedica, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34115340&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1109652(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmedica, Inc. filed Critical Boehringer Ingelheim Vetmedica, Inc.
Publication of CY1109652T1 publication Critical patent/CY1109652T1/el

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/105Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/825Bacterial vaccine for porcine species, e.g. swine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε εμβόλια κατά του Lawsonia intracellularis και σε μεθόδους προστασίας από και διαγνώσεως της μολύνσεως από το L. intracellularis. Τα προϊόντα και οι μέθοδοι της εφευρέσεως είναι δυνατά, εν μέρει, ως αποτέλεσμα μίας βελτιωμένης μεθόδου καλλιέργειας αποθεμάτων μεγάλης κλίμακας του L. intracellularis, περιλαμβανομένης τόσο μίας νέας απομονώσεως του L. intracellularis Ευρωπαϊκής προελεύσεως όσο και μίας μεθόδου παρασκευής ενός λυοφιλοποιημένου προϊόντος περιέχοντος την εξασθενημένη Ευρωπαϊκή απομόνωση ως προϊόντος εμβολίου.
CY20091101223T 2003-07-25 2009-11-25 Lawsonia intracellularis ευρωπαϊκης προελευσεως και εμβολια, διαγνωστικοι παραγοντες και μεθοδοι χρησεως τους CY1109652T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49000103P 2003-07-25 2003-07-25
EP04778282.6A EP1651260B2 (en) 2003-07-25 2004-07-15 Lawsonia intracellularis of european origin and vaccines, diagnostic agents and methods of use thereof

Publications (1)

Publication Number Publication Date
CY1109652T1 true CY1109652T1 (el) 2014-08-13

Family

ID=34115340

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091101223T CY1109652T1 (el) 2003-07-25 2009-11-25 Lawsonia intracellularis ευρωπαϊκης προελευσεως και εμβολια, διαγνωστικοι παραγοντες και μεθοδοι χρησεως τους

Country Status (23)

Country Link
US (2) US7312065B2 (el)
EP (1) EP1651260B2 (el)
JP (1) JP2006528882A (el)
KR (1) KR101131845B1 (el)
CN (2) CN101423811A (el)
AT (1) ATE442163T2 (el)
AU (1) AU2004260657B2 (el)
BR (1) BRPI0412911B1 (el)
CA (1) CA2533559C (el)
CY (1) CY1109652T1 (el)
DE (1) DE602004023094D1 (el)
DK (1) DK1651260T4 (el)
ES (1) ES2333334T5 (el)
MX (1) MXPA06000994A (el)
MY (1) MY140208A (el)
PL (1) PL1651260T5 (el)
PT (1) PT1651260E (el)
RU (1) RU2420570C2 (el)
SG (1) SG144909A1 (el)
SI (1) SI1651260T2 (el)
UA (1) UA87665C2 (el)
WO (1) WO2005011731A1 (el)
ZA (1) ZA200510081B (el)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
AU2012207016B2 (en) * 2005-03-14 2015-01-15 Boehringer Ingelheim Animal Health USA Inc. Immunogenic compositions comprising Lawsonia intracellularis
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
US8398994B2 (en) * 2005-07-15 2013-03-19 Boehringer Ingelheim Vetmedica, Inc. Lawsonia vaccine and methods of use thereof
MX338626B (es) 2005-12-29 2016-04-26 Boehringer Ingelheim Vetmed Uso de una composicion inmunogenica de pcv2 para producir los sintomas clinicos en cerdos.
JP5394750B2 (ja) 2005-12-29 2014-01-22 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド 多価pcv2免疫原性組成物及び当該組成物を製造する方法
US8470336B2 (en) * 2006-05-25 2013-06-25 Boehringer Ingelheim Vetmedica, Inc. Vaccination of young animals against Lawsonia intracellularis infections
US20080241190A1 (en) * 2006-11-13 2008-10-02 Boehringer Ingelheim Vetmedica, Inc. Vaccination of horses against lawsonia intracellularis
EP2099927A4 (en) * 2006-11-22 2010-05-05 Boehringer Ingelheim Vetmed METHODS FOR REDUCING FLAMBEES OF DISEASES ASSOCIATED WITH PORCINIC CIRCOVIRUS
WO2008073464A2 (en) 2006-12-11 2008-06-19 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
PL2481420T3 (pl) * 2006-12-15 2019-08-30 Boehringer Ingelheim Animal Health USA Inc. Jednodawkowa szczepionka anty-PCV2 dla świń
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
TW200918666A (en) * 2007-09-11 2009-05-01 Wyeth Corp Attenuated mycoplasma gallisepticum strains
WO2009037262A2 (en) * 2007-09-17 2009-03-26 Boehringer Ingelheim Vetmedica, Inc. Method of preventing early lawsonia intracellularis infections
CN101932336B (zh) * 2007-12-31 2014-07-09 贝林格尔.英格海姆维特梅迪卡有限公司 有外来氨基酸插入的pcv2 orf2病毒样颗粒
CN101980720A (zh) 2008-01-23 2011-02-23 贝林格尔.英格海姆维特梅迪卡有限公司 Pcv2猪肺炎支原体致免疫组合物及其制备方法
WO2009103037A1 (en) * 2008-02-15 2009-08-20 Boehringer Ingelheim Vetmedica, Inc. Methods and compositions for reducing the impact of enteric diseases
TWI449533B (zh) * 2008-04-18 2014-08-21 Intervet Int Bv 防備胞內勞森菌(Lawsonia intracellularis)、豬肺炎黴漿菌(Mycoplasma hyopneumoniae)及豬環狀病毒(Porcine circo virus)用疫苗
TWI551295B (zh) * 2008-04-18 2016-10-01 英特威特國際股份有限公司 防備胞內勞森菌(Lawsonia intracellularis)用疫苗
JP5723772B2 (ja) * 2008-07-22 2015-05-27 インターベット インターナショナル ベー. フェー. 新規血清型のローソニア・イントラセルラリス細菌、その細菌に基づくワクチン、該新規ローソニア・イントラセルラリス血清型の特定に適した抗体および該抗体を製造するためのハイブリドーマ
US8142760B2 (en) * 2008-09-05 2012-03-27 Nathan Len Winkelman Vaccination for Lawsonia intracellularis
WO2011006880A1 (en) * 2009-07-14 2011-01-20 Intervet International B.V. Lawsonia intracellularis propagation
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物
US8530223B2 (en) 2009-11-09 2013-09-10 Intervet International B.V. Method to grow Lawsonia intracellularis bacteria in persistently infected McCoy cells
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
DK2691530T3 (en) 2011-06-10 2018-05-22 Univ Oregon Health & Science CMV GLYCOPROTEIN AND RECOMBINANT VECTORS
BR112016006192A2 (pt) 2013-09-25 2017-09-26 Zoetis Services Llc composição de vacina de divergente de pcv2b e métodos de uso
ES2778425T3 (es) 2013-10-02 2020-08-10 Boehringer Ingelheim Animal Health Usa Inc Variante de la proteína ORF2 del PCV2 y partículas similares a virus compuestas por esta
RU2672251C1 (ru) * 2013-12-03 2018-11-13 Интервет Интернэшнл Б.В. Вакцина против lawsonia intracellularis и свиного цирковируса 2-го типа
CN103823063B (zh) * 2014-02-25 2015-09-30 上海理工大学 检测猪霍乱沙门氏菌的方法及其单抗
RU2709197C2 (ru) 2015-02-04 2019-12-17 Интервет Интернэшнл Б.В. Вакцина для применения против субклинической инфекции lawsonia у свиней
KR101893827B1 (ko) * 2016-01-04 2018-08-31 전북대학교 산학협력단 약독화된 살모넬라 변이주를 유효성분으로 포함하는 돼지 증식성 회장염 및 살모넬라증 동시 예방 또는 치료용 백신 조성물
WO2019166362A1 (en) 2018-02-28 2019-09-06 Boehringer Ingelheim Vetmedica Gmbh Method for reducing skatole and/or indole in animals
KR102249189B1 (ko) * 2020-01-09 2021-05-07 전북대학교 산학협력단 항원성이 증진된 항원을 발현하는 약독화된 살모넬라 변이주를 유효성분으로 포함하는 돼지 증식성 회장염 및 살모넬라증 동시 예방 또는 치료용 백신 조성물
MX2023001024A (es) * 2020-07-24 2023-02-15 Boehringer Ingelheim Animal Health Usa Inc Vacuna porcina combinada.
CN111961627A (zh) * 2020-08-27 2020-11-20 南京农业大学 一种胞内劳森菌的分离与培养方法
EP4426342A1 (en) 2021-11-01 2024-09-11 Boehringer Ingelheim Vetmedica GmbH Immunogenic gel compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5885823A (en) 1995-06-05 1999-03-23 Nobl Laboratories, Inc. Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents
US5714375A (en) * 1995-06-05 1998-02-03 Nobl Laboratories, Inc. Ileal symbiont intracellularis propagation in suspended host cells

Also Published As

Publication number Publication date
AU2004260657A1 (en) 2005-02-10
ZA200510081B (en) 2006-08-30
CN101423811A (zh) 2009-05-06
SI1651260T2 (sl) 2018-09-28
AU2004260657B2 (en) 2012-06-07
PT1651260E (pt) 2009-09-24
DE602004023094D1 (de) 2009-10-22
MY140208A (en) 2009-11-30
RU2420570C2 (ru) 2011-06-10
DK1651260T4 (en) 2018-10-08
BRPI0412911A (pt) 2006-09-26
EP1651260A1 (en) 2006-05-03
ES2333334T5 (es) 2018-08-06
CA2533559A1 (en) 2005-02-10
ATE442163T2 (de) 2009-09-15
EP1651260B2 (en) 2018-06-27
ES2333334T3 (es) 2010-02-19
SI1651260T1 (sl) 2010-01-29
EP1651260B1 (en) 2009-09-09
CN1829529A (zh) 2006-09-06
PL1651260T3 (pl) 2010-02-26
RU2006105715A (ru) 2007-09-10
US7758870B2 (en) 2010-07-20
US20050031647A1 (en) 2005-02-10
US20080112980A1 (en) 2008-05-15
MXPA06000994A (es) 2006-05-15
KR101131845B1 (ko) 2012-03-30
KR20060054352A (ko) 2006-05-22
PL1651260T5 (pl) 2018-11-30
DK1651260T3 (da) 2010-01-11
WO2005011731A1 (en) 2005-02-10
JP2006528882A (ja) 2006-12-28
CA2533559C (en) 2013-07-02
UA87665C2 (ru) 2009-08-10
BRPI0412911B1 (pt) 2020-01-21
SG144909A1 (en) 2008-08-28
CN1829529B (zh) 2011-05-04
US7312065B2 (en) 2007-12-25

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