CY1109652T1 - Lawsonia intracellularis ευρωπαϊκης προελευσεως και εμβολια, διαγνωστικοι παραγοντες και μεθοδοι χρησεως τους - Google Patents
Lawsonia intracellularis ευρωπαϊκης προελευσεως και εμβολια, διαγνωστικοι παραγοντες και μεθοδοι χρησεως τουςInfo
- Publication number
- CY1109652T1 CY1109652T1 CY20091101223T CY091101223T CY1109652T1 CY 1109652 T1 CY1109652 T1 CY 1109652T1 CY 20091101223 T CY20091101223 T CY 20091101223T CY 091101223 T CY091101223 T CY 091101223T CY 1109652 T1 CY1109652 T1 CY 1109652T1
- Authority
- CY
- Cyprus
- Prior art keywords
- methods
- intracellularis
- vaccines
- lawsonia intracellularis
- european origin
- Prior art date
Links
- 241001148567 Lawsonia intracellularis Species 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/825—Bacterial vaccine for porcine species, e.g. swine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται σε εμβόλια κατά του Lawsonia intracellularis και σε μεθόδους προστασίας από και διαγνώσεως της μολύνσεως από το L. intracellularis. Τα προϊόντα και οι μέθοδοι της εφευρέσεως είναι δυνατά, εν μέρει, ως αποτέλεσμα μίας βελτιωμένης μεθόδου καλλιέργειας αποθεμάτων μεγάλης κλίμακας του L. intracellularis, περιλαμβανομένης τόσο μίας νέας απομονώσεως του L. intracellularis Ευρωπαϊκής προελεύσεως όσο και μίας μεθόδου παρασκευής ενός λυοφιλοποιημένου προϊόντος περιέχοντος την εξασθενημένη Ευρωπαϊκή απομόνωση ως προϊόντος εμβολίου.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49000103P | 2003-07-25 | 2003-07-25 | |
EP04778282.6A EP1651260B2 (en) | 2003-07-25 | 2004-07-15 | Lawsonia intracellularis of european origin and vaccines, diagnostic agents and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1109652T1 true CY1109652T1 (el) | 2014-08-13 |
Family
ID=34115340
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20091101223T CY1109652T1 (el) | 2003-07-25 | 2009-11-25 | Lawsonia intracellularis ευρωπαϊκης προελευσεως και εμβολια, διαγνωστικοι παραγοντες και μεθοδοι χρησεως τους |
Country Status (23)
Country | Link |
---|---|
US (2) | US7312065B2 (el) |
EP (1) | EP1651260B2 (el) |
JP (1) | JP2006528882A (el) |
KR (1) | KR101131845B1 (el) |
CN (2) | CN101423811A (el) |
AT (1) | ATE442163T2 (el) |
AU (1) | AU2004260657B2 (el) |
BR (1) | BRPI0412911B1 (el) |
CA (1) | CA2533559C (el) |
CY (1) | CY1109652T1 (el) |
DE (1) | DE602004023094D1 (el) |
DK (1) | DK1651260T4 (el) |
ES (1) | ES2333334T5 (el) |
MX (1) | MXPA06000994A (el) |
MY (1) | MY140208A (el) |
PL (1) | PL1651260T5 (el) |
PT (1) | PT1651260E (el) |
RU (1) | RU2420570C2 (el) |
SG (1) | SG144909A1 (el) |
SI (1) | SI1651260T2 (el) |
UA (1) | UA87665C2 (el) |
WO (1) | WO2005011731A1 (el) |
ZA (1) | ZA200510081B (el) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
US7833707B2 (en) | 2004-12-30 | 2010-11-16 | Boehringer Ingelheim Vetmedica, Inc. | Methods of overexpression and recovery of porcine circovirus type 2 ORF2 |
UA95602C2 (ru) | 2004-12-30 | 2011-08-25 | Берингер Ингельхейм Ветмедика, Инк. | Иммуногенная композиция цвс2 и способы приготовления такой композиции |
AU2012207016B2 (en) * | 2005-03-14 | 2015-01-15 | Boehringer Ingelheim Animal Health USA Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
US8834891B2 (en) | 2005-03-14 | 2014-09-16 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
US8398994B2 (en) * | 2005-07-15 | 2013-03-19 | Boehringer Ingelheim Vetmedica, Inc. | Lawsonia vaccine and methods of use thereof |
MX338626B (es) | 2005-12-29 | 2016-04-26 | Boehringer Ingelheim Vetmed | Uso de una composicion inmunogenica de pcv2 para producir los sintomas clinicos en cerdos. |
JP5394750B2 (ja) | 2005-12-29 | 2014-01-22 | ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド | 多価pcv2免疫原性組成物及び当該組成物を製造する方法 |
US8470336B2 (en) * | 2006-05-25 | 2013-06-25 | Boehringer Ingelheim Vetmedica, Inc. | Vaccination of young animals against Lawsonia intracellularis infections |
US20080241190A1 (en) * | 2006-11-13 | 2008-10-02 | Boehringer Ingelheim Vetmedica, Inc. | Vaccination of horses against lawsonia intracellularis |
EP2099927A4 (en) * | 2006-11-22 | 2010-05-05 | Boehringer Ingelheim Vetmed | METHODS FOR REDUCING FLAMBEES OF DISEASES ASSOCIATED WITH PORCINIC CIRCOVIRUS |
WO2008073464A2 (en) | 2006-12-11 | 2008-06-19 | Boehringer Ingelheim Vetmedica, Inc. | Effective method of treatment of porcine circovirus and lawsonia intracellularis infections |
PL2481420T3 (pl) * | 2006-12-15 | 2019-08-30 | Boehringer Ingelheim Animal Health USA Inc. | Jednodawkowa szczepionka anty-PCV2 dla świń |
EP1941903A1 (en) | 2007-01-03 | 2008-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Prophylaxis and treatment of PRDC |
EP1958644A1 (en) | 2007-02-13 | 2008-08-20 | Boehringer Ingelheim Vetmedica Gmbh | Prevention and treatment of sub-clinical pcvd |
US7829274B2 (en) * | 2007-09-04 | 2010-11-09 | Boehringer Ingelheim Vetmedica, Inc. | Reduction of concomitant infections in pigs by the use of PCV2 antigen |
TW200918666A (en) * | 2007-09-11 | 2009-05-01 | Wyeth Corp | Attenuated mycoplasma gallisepticum strains |
WO2009037262A2 (en) * | 2007-09-17 | 2009-03-26 | Boehringer Ingelheim Vetmedica, Inc. | Method of preventing early lawsonia intracellularis infections |
CN101932336B (zh) * | 2007-12-31 | 2014-07-09 | 贝林格尔.英格海姆维特梅迪卡有限公司 | 有外来氨基酸插入的pcv2 orf2病毒样颗粒 |
CN101980720A (zh) | 2008-01-23 | 2011-02-23 | 贝林格尔.英格海姆维特梅迪卡有限公司 | Pcv2猪肺炎支原体致免疫组合物及其制备方法 |
WO2009103037A1 (en) * | 2008-02-15 | 2009-08-20 | Boehringer Ingelheim Vetmedica, Inc. | Methods and compositions for reducing the impact of enteric diseases |
TWI449533B (zh) * | 2008-04-18 | 2014-08-21 | Intervet Int Bv | 防備胞內勞森菌(Lawsonia intracellularis)、豬肺炎黴漿菌(Mycoplasma hyopneumoniae)及豬環狀病毒(Porcine circo virus)用疫苗 |
TWI551295B (zh) * | 2008-04-18 | 2016-10-01 | 英特威特國際股份有限公司 | 防備胞內勞森菌(Lawsonia intracellularis)用疫苗 |
JP5723772B2 (ja) * | 2008-07-22 | 2015-05-27 | インターベット インターナショナル ベー. フェー. | 新規血清型のローソニア・イントラセルラリス細菌、その細菌に基づくワクチン、該新規ローソニア・イントラセルラリス血清型の特定に適した抗体および該抗体を製造するためのハイブリドーマ |
US8142760B2 (en) * | 2008-09-05 | 2012-03-27 | Nathan Len Winkelman | Vaccination for Lawsonia intracellularis |
WO2011006880A1 (en) * | 2009-07-14 | 2011-01-20 | Intervet International B.V. | Lawsonia intracellularis propagation |
TWI627281B (zh) | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物 |
US8530223B2 (en) | 2009-11-09 | 2013-09-10 | Intervet International B.V. | Method to grow Lawsonia intracellularis bacteria in persistently infected McCoy cells |
WO2011119920A2 (en) | 2010-03-25 | 2011-09-29 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
DK2691530T3 (en) | 2011-06-10 | 2018-05-22 | Univ Oregon Health & Science | CMV GLYCOPROTEIN AND RECOMBINANT VECTORS |
BR112016006192A2 (pt) | 2013-09-25 | 2017-09-26 | Zoetis Services Llc | composição de vacina de divergente de pcv2b e métodos de uso |
ES2778425T3 (es) | 2013-10-02 | 2020-08-10 | Boehringer Ingelheim Animal Health Usa Inc | Variante de la proteína ORF2 del PCV2 y partículas similares a virus compuestas por esta |
RU2672251C1 (ru) * | 2013-12-03 | 2018-11-13 | Интервет Интернэшнл Б.В. | Вакцина против lawsonia intracellularis и свиного цирковируса 2-го типа |
CN103823063B (zh) * | 2014-02-25 | 2015-09-30 | 上海理工大学 | 检测猪霍乱沙门氏菌的方法及其单抗 |
RU2709197C2 (ru) | 2015-02-04 | 2019-12-17 | Интервет Интернэшнл Б.В. | Вакцина для применения против субклинической инфекции lawsonia у свиней |
KR101893827B1 (ko) * | 2016-01-04 | 2018-08-31 | 전북대학교 산학협력단 | 약독화된 살모넬라 변이주를 유효성분으로 포함하는 돼지 증식성 회장염 및 살모넬라증 동시 예방 또는 치료용 백신 조성물 |
WO2019166362A1 (en) | 2018-02-28 | 2019-09-06 | Boehringer Ingelheim Vetmedica Gmbh | Method for reducing skatole and/or indole in animals |
KR102249189B1 (ko) * | 2020-01-09 | 2021-05-07 | 전북대학교 산학협력단 | 항원성이 증진된 항원을 발현하는 약독화된 살모넬라 변이주를 유효성분으로 포함하는 돼지 증식성 회장염 및 살모넬라증 동시 예방 또는 치료용 백신 조성물 |
MX2023001024A (es) * | 2020-07-24 | 2023-02-15 | Boehringer Ingelheim Animal Health Usa Inc | Vacuna porcina combinada. |
CN111961627A (zh) * | 2020-08-27 | 2020-11-20 | 南京农业大学 | 一种胞内劳森菌的分离与培养方法 |
EP4426342A1 (en) | 2021-11-01 | 2024-09-11 | Boehringer Ingelheim Vetmedica GmbH | Immunogenic gel compositions |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5885823A (en) | 1995-06-05 | 1999-03-23 | Nobl Laboratories, Inc. | Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents |
US5714375A (en) * | 1995-06-05 | 1998-02-03 | Nobl Laboratories, Inc. | Ileal symbiont intracellularis propagation in suspended host cells |
-
2004
- 2004-07-15 ES ES04778282.6T patent/ES2333334T5/es not_active Expired - Lifetime
- 2004-07-15 CA CA2533559A patent/CA2533559C/en not_active Expired - Lifetime
- 2004-07-15 US US10/891,745 patent/US7312065B2/en active Active
- 2004-07-15 SG SG200805019-7A patent/SG144909A1/en unknown
- 2004-07-15 KR KR1020067001755A patent/KR101131845B1/ko active IP Right Grant
- 2004-07-15 CN CNA2008101760745A patent/CN101423811A/zh active Pending
- 2004-07-15 WO PCT/US2004/022704 patent/WO2005011731A1/en active Application Filing
- 2004-07-15 AU AU2004260657A patent/AU2004260657B2/en not_active Expired
- 2004-07-15 EP EP04778282.6A patent/EP1651260B2/en not_active Expired - Lifetime
- 2004-07-15 AT AT04778282T patent/ATE442163T2/de active
- 2004-07-15 BR BRPI0412911A patent/BRPI0412911B1/pt active IP Right Grant
- 2004-07-15 CN CN200480021627XA patent/CN1829529B/zh not_active Expired - Lifetime
- 2004-07-15 DE DE602004023094T patent/DE602004023094D1/de not_active Expired - Lifetime
- 2004-07-15 RU RU2006105715/10A patent/RU2420570C2/ru active
- 2004-07-15 DK DK04778282.6T patent/DK1651260T4/en active
- 2004-07-15 PL PL04778282T patent/PL1651260T5/pl unknown
- 2004-07-15 UA UAA200601775A patent/UA87665C2/ru unknown
- 2004-07-15 JP JP2006521125A patent/JP2006528882A/ja active Pending
- 2004-07-15 PT PT04778282T patent/PT1651260E/pt unknown
- 2004-07-15 MX MXPA06000994A patent/MXPA06000994A/es active IP Right Grant
- 2004-07-15 SI SI200431296T patent/SI1651260T2/sl unknown
- 2004-07-23 MY MYPI20042965A patent/MY140208A/en unknown
-
2005
- 2005-12-12 ZA ZA200510081A patent/ZA200510081B/en unknown
-
2007
- 2007-11-06 US US11/935,447 patent/US7758870B2/en not_active Expired - Lifetime
-
2009
- 2009-11-25 CY CY20091101223T patent/CY1109652T1/el unknown
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