CY1108662T1 - ΑΝΘΡΩΠΙΝΗ ΕΞΑΡΤΩΜΕΝΗ ΑΠΟ ΚΥΚΛΙΝΗ ΚΙΝΑΣΗ (hPNQALRE) - Google Patents
ΑΝΘΡΩΠΙΝΗ ΕΞΑΡΤΩΜΕΝΗ ΑΠΟ ΚΥΚΛΙΝΗ ΚΙΝΑΣΗ (hPNQALRE)Info
- Publication number
- CY1108662T1 CY1108662T1 CY20081101453T CY081101453T CY1108662T1 CY 1108662 T1 CY1108662 T1 CY 1108662T1 CY 20081101453 T CY20081101453 T CY 20081101453T CY 081101453 T CY081101453 T CY 081101453T CY 1108662 T1 CY1108662 T1 CY 1108662T1
- Authority
- CY
- Cyprus
- Prior art keywords
- hpnqalre
- motion
- human
- cycline
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Το ανθρώπινο γονίδιο το οποίο κωδικοποιεί μια νέα εξαρτώμενη από κυκλίνη κινάση ονομαζόμενη hPNQALRE και τα προϊόντα εκφράσεως του μπορούν να χρησιμοποιηθούν για να παράσχουν αντιδραστήρια και μεθόδους για τον εντοπισμό νεοπλασίας. Παρέχονται επίσης συνθέσεις και μέθοδοι για την αγωγή πολλαπλασιαστικών διαταραχών και νεοπλασιών.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11249798P | 1998-12-16 | 1998-12-16 | |
US46406599A | 1999-12-15 | 1999-12-15 | |
EP99967389A EP1141331B1 (en) | 1998-12-16 | 1999-12-16 | HUMAN CYCLIN-DEPENDENT KINASE (hPNQALRE) |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108662T1 true CY1108662T1 (el) | 2014-04-09 |
Family
ID=26810024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20081101453T CY1108662T1 (el) | 1998-12-16 | 2008-12-16 | ΑΝΘΡΩΠΙΝΗ ΕΞΑΡΤΩΜΕΝΗ ΑΠΟ ΚΥΚΛΙΝΗ ΚΙΝΑΣΗ (hPNQALRE) |
Country Status (11)
Country | Link |
---|---|
US (3) | US7250256B2 (el) |
EP (2) | EP1961813B1 (el) |
JP (3) | JP2003524389A (el) |
AT (2) | ATE519840T1 (el) |
AU (1) | AU2367600A (el) |
CY (1) | CY1108662T1 (el) |
DE (1) | DE69939599D1 (el) |
DK (1) | DK1141331T3 (el) |
ES (1) | ES2310055T3 (el) |
PT (1) | PT1141331E (el) |
WO (1) | WO2000036118A2 (el) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE519840T1 (de) * | 1998-12-16 | 2011-08-15 | Novartis Vaccines & Diagnostic | Menschliche cyclin-abhängige kinase (hpnqalre) |
US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
US20070192884A1 (en) * | 2006-01-25 | 2007-08-16 | Daniel Chelsky | TAT-038 and methods of assessing and treating cancer |
US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
WO2007147074A2 (en) | 2006-06-14 | 2007-12-21 | Living Microsystems, Inc. | Use of highly parallel snp genotyping for fetal diagnosis |
US8372584B2 (en) | 2006-06-14 | 2013-02-12 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
EP2205249B1 (en) | 2007-09-28 | 2018-11-07 | Intrexon Corporation | Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof |
CA3069081C (en) | 2008-09-20 | 2023-05-23 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
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ATE519840T1 (de) | 1998-12-16 | 2011-08-15 | Novartis Vaccines & Diagnostic | Menschliche cyclin-abhängige kinase (hpnqalre) |
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-
1999
- 1999-12-16 AT AT08006175T patent/ATE519840T1/de not_active IP Right Cessation
- 1999-12-16 WO PCT/US1999/030113 patent/WO2000036118A2/en active Application Filing
- 1999-12-16 PT PT99967389T patent/PT1141331E/pt unknown
- 1999-12-16 DE DE69939599T patent/DE69939599D1/de not_active Expired - Lifetime
- 1999-12-16 EP EP08006175A patent/EP1961813B1/en not_active Expired - Lifetime
- 1999-12-16 DK DK99967389T patent/DK1141331T3/da active
- 1999-12-16 EP EP99967389A patent/EP1141331B1/en not_active Expired - Lifetime
- 1999-12-16 ES ES99967389T patent/ES2310055T3/es not_active Expired - Lifetime
- 1999-12-16 JP JP2000588367A patent/JP2003524389A/ja not_active Withdrawn
- 1999-12-16 AU AU23676/00A patent/AU2367600A/en not_active Abandoned
- 1999-12-16 AT AT99967389T patent/ATE408695T1/de active
-
2003
- 2003-09-16 US US10/663,896 patent/US7250256B2/en not_active Expired - Fee Related
-
2007
- 2007-06-07 US US11/759,726 patent/US7855058B2/en not_active Expired - Fee Related
- 2007-07-06 US US11/774,306 patent/US7566559B2/en not_active Expired - Fee Related
-
2008
- 2008-12-16 CY CY20081101453T patent/CY1108662T1/el unknown
-
2010
- 2010-03-04 JP JP2010048410A patent/JP2010162036A/ja not_active Withdrawn
-
2013
- 2013-05-07 JP JP2013097306A patent/JP2013162795A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1961813B1 (en) | 2011-08-10 |
US20080050797A1 (en) | 2008-02-28 |
US7250256B2 (en) | 2007-07-31 |
ES2310055T3 (es) | 2008-12-16 |
US7566559B2 (en) | 2009-07-28 |
EP1961813A3 (en) | 2009-01-21 |
ATE408695T1 (de) | 2008-10-15 |
WO2000036118A3 (en) | 2000-11-16 |
JP2010162036A (ja) | 2010-07-29 |
WO2000036118A2 (en) | 2000-06-22 |
EP1141331A2 (en) | 2001-10-10 |
DE69939599D1 (de) | 2008-10-30 |
EP1141331B1 (en) | 2008-09-17 |
ATE519840T1 (de) | 2011-08-15 |
US20080176279A1 (en) | 2008-07-24 |
US7855058B2 (en) | 2010-12-21 |
PT1141331E (pt) | 2008-12-22 |
DK1141331T3 (da) | 2009-01-05 |
EP1961813A2 (en) | 2008-08-27 |
AU2367600A (en) | 2000-07-03 |
JP2013162795A (ja) | 2013-08-22 |
US20040077009A1 (en) | 2004-04-22 |
JP2003524389A (ja) | 2003-08-19 |
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