CY1108329T1 - Κυτταρικη καλλιεργεια - Google Patents
Κυτταρικη καλλιεργειαInfo
- Publication number
- CY1108329T1 CY1108329T1 CY20081100975T CY081100975T CY1108329T1 CY 1108329 T1 CY1108329 T1 CY 1108329T1 CY 20081100975 T CY20081100975 T CY 20081100975T CY 081100975 T CY081100975 T CY 081100975T CY 1108329 T1 CY1108329 T1 CY 1108329T1
- Authority
- CY
- Cyprus
- Prior art keywords
- cells
- obtaining
- culture medium
- stem cells
- cultivation
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H4/00—Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
- A01H4/005—Methods for micropropagation; Vegetative plant propagation using cell or tissue culture techniques
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H4/00—Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
- A01H4/008—Methods for regeneration to complete plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2531/00—Microcarriers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0031—Serum-free culture media
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P39/00—Processes involving microorganisms of different genera in the same process, simultaneously
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Μία μέθοδος για προσδιορισμό της επίδρασης ενός μεγάλου αριθμού συνθηκών καλλιέργειας σε ένα κύτταρο, η οποία περιλαμβάνει τα στάδια: a) της παροχής ενός πρώτου συνόλου κυτταρικών μονάδων με κάθε μία να περιλαμβάνει ένα ή περισσότερα κύτταρα, και της έκθεσης των εν λόγω ομάδων σε επιθυμητές συνθήκες καλλιέργειας·(b) της συνένωσης δύο ή περισσότερων εκ των εν λόγω ομάδων για να σχηματιστεί τουλάχιστον ένα δεύτερο συνένωμα· (c) της υποδιαίρεσης του δεύτερου συνενώματος για να δημιουργηθεί ένα περαιτέρω σύνολο ομάδων κυτταρικών μονάδων· (d) της έκθεσης των εν λόγω περαιτέρω ομάδων σε επιθυμητές συνθήκες καλλιέργειας· (e) κατ' επιλογή, της επανάληψης των σταδίων (b) -(d) επαναληπτικά όσο απαιτείται·και (f) κατ' επιλογή της εκτίμησης της επίδρασης σε μια δεδομένη κυτταρική μονάδα των συνθηκών καλλιέργειας στις οποίες αυτή έχει εκτεθεί.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0222846.8A GB0222846D0 (en) | 2002-10-03 | 2002-10-03 | Cell culture |
EP03753734A EP1551954B1 (en) | 2002-10-03 | 2003-10-03 | Cell culture |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108329T1 true CY1108329T1 (el) | 2014-02-12 |
Family
ID=9945172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20081100975T CY1108329T1 (el) | 2002-10-03 | 2008-09-10 | Κυτταρικη καλλιεργεια |
Country Status (15)
Country | Link |
---|---|
US (3) | US8114669B2 (el) |
EP (2) | EP1551954B1 (el) |
JP (2) | JP4820091B2 (el) |
CN (2) | CN103205393B (el) |
AT (1) | ATE398170T1 (el) |
AU (1) | AU2003271896B2 (el) |
CA (1) | CA2501280C (el) |
CY (1) | CY1108329T1 (el) |
DE (1) | DE60321585D1 (el) |
DK (2) | DK1551954T3 (el) |
ES (1) | ES2307969T3 (el) |
GB (1) | GB0222846D0 (el) |
PT (1) | PT1551954E (el) |
SG (1) | SG155050A1 (el) |
WO (1) | WO2004031369A1 (el) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0222846D0 (en) | 2002-10-03 | 2002-11-06 | Choo Yen | Cell culture |
DE102004043256B4 (de) * | 2004-09-07 | 2013-09-19 | Rheinische Friedrich-Wilhelms-Universität Bonn | Skalierbarer Prozess zur Kultivierung undifferenzierter Stammzellen in Suspension |
DE102004049290A1 (de) * | 2004-10-09 | 2006-04-20 | Bayer Healthcare Ag | Verfahren zur Herstellung von Virusmaterial |
GB0517382D0 (en) * | 2005-08-26 | 2005-10-05 | Plasticell Ltd | Cell culture |
AU2006286149B2 (en) | 2005-08-29 | 2012-09-13 | Technion Research And Development Foundation Ltd. | Media for culturing stem cells |
GB0526664D0 (en) | 2005-11-30 | 2006-02-08 | Plasticell Ltd | Method |
DK3441459T3 (da) | 2006-08-02 | 2021-06-07 | Technion Res & Dev Foundation | Fremgangsmåder til ekspansion af embryonale stamceller i en suspensionskultur |
DE102006060247A1 (de) * | 2006-09-15 | 2008-03-27 | Ossacur Ag | Differenzierung von Stammzellen |
PL2089511T3 (pl) * | 2006-11-13 | 2015-02-27 | Depuy Synthes Products Llc | Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki |
GB0703188D0 (en) * | 2007-02-19 | 2007-03-28 | Roger Land Building | Large scale production of stem cells |
WO2008116468A2 (en) | 2007-03-26 | 2008-10-02 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
EP3620465A1 (en) * | 2007-07-03 | 2020-03-11 | Dako Denmark A/S | Improved methods for generation, labeling and use of mhc multimers |
EP2197908A2 (en) * | 2007-09-27 | 2010-06-23 | Dako Denmark A/S | Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics |
US10968269B1 (en) | 2008-02-28 | 2021-04-06 | Agilent Technologies, Inc. | MHC multimers in borrelia diagnostics and disease |
WO2010009735A2 (en) | 2008-07-23 | 2010-01-28 | Dako Denmark A/S | Combinatorial analysis and repair |
GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
US10369204B2 (en) | 2008-10-02 | 2019-08-06 | Dako Denmark A/S | Molecular vaccines for infectious disease |
GB0914195D0 (en) | 2009-08-13 | 2009-09-16 | Plasticell Ltd | Vessel for culturing cells |
GB0916585D0 (en) | 2009-09-21 | 2009-10-28 | Plasticell Ltd | Apparatus and method for processing cell culture data |
GB0918564D0 (en) * | 2009-10-22 | 2009-12-09 | Plasticell Ltd | Nested cell encapsulation |
CA2780320A1 (en) * | 2009-11-12 | 2011-05-19 | Tengion, Inc. | Rational design of regenerative medicine products |
JP4717149B1 (ja) * | 2010-06-07 | 2011-07-06 | 独立行政法人沖縄科学技術研究基盤整備機構 | 細胞選択装置、細胞選択方法、および、プログラム |
WO2012007725A2 (en) | 2010-07-16 | 2012-01-19 | Plasticell Ltd | Method of reprogramming a cell |
CN102466730A (zh) * | 2010-11-19 | 2012-05-23 | 南京神州英诺华医疗科技有限公司 | 一种新的配制血型反定型试剂的方法 |
ES2687761T3 (es) * | 2011-01-31 | 2018-10-29 | F. Hoffmann-La Roche Ag | Métodos de identificación de múltiples epítopos en células |
US11560585B2 (en) | 2011-01-31 | 2023-01-24 | Roche Sequencing Solutions, Inc. | Methods of identifying multiple epitopes in cells |
US8966868B2 (en) * | 2011-05-09 | 2015-03-03 | Abbott Cardiovascular Systems Inc. | Methods of stabilizing molecular weight of polymer stents after sterilization |
US20130274114A1 (en) * | 2011-09-28 | 2013-10-17 | Saint Peter's University | Multipotent stem cell-based culture systems and models |
CN102965333A (zh) * | 2012-12-13 | 2013-03-13 | 李伟 | 一种原代细胞大规模继代培养的方法 |
SG11201609025TA (en) | 2014-05-02 | 2016-11-29 | Malaysian Palm Oil Board | Mantle phenotype detection in palm |
US11291756B2 (en) | 2016-07-28 | 2022-04-05 | The Charles Stark Draper Laboratory, Inc. | Acoustic separation for bioprocessing |
WO2018201034A1 (en) | 2017-04-28 | 2018-11-01 | The Charles Stark Draper Laboratory, Inc. | Acoustic separation of particles for bioprocessing |
GB201707143D0 (en) | 2017-05-04 | 2017-06-21 | Plasticell Ltd | Method for producing cells |
CN109593704B (zh) * | 2019-01-31 | 2022-02-11 | 北京华龛生物科技有限公司 | 一种三维微载体细胞吸附培养的方法 |
DE102019134003A1 (de) | 2019-12-11 | 2021-06-17 | Aixinno Limited | Verfahren und Vorrichtung zum Kultivieren biologischer Zellen |
CN113249307B (zh) * | 2021-04-23 | 2023-01-31 | 北京大学 | 一种维生素d3及其类似物在促进癌细胞分化成脂肪细胞中的应用 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2675408B2 (ja) * | 1989-09-14 | 1997-11-12 | 宇部興産株式会社 | 中空糸膜型バイオリアクター |
US5635387A (en) * | 1990-04-23 | 1997-06-03 | Cellpro, Inc. | Methods and device for culturing human hematopoietic cells and their precursors |
US5192238A (en) * | 1992-07-14 | 1993-03-09 | Brown John B | Self-activated man overboard recovery system |
GB9308271D0 (en) | 1993-04-21 | 1993-06-02 | Univ Edinburgh | Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method |
US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
CN1112604A (zh) * | 1994-05-26 | 1995-11-29 | 中国林业科学研究院亚热带林业研究所 | 人参组织和细胞富锗培养 |
US5827742A (en) | 1994-09-01 | 1998-10-27 | Beth Israel Deaconess Medical Center, Inc. | Method of selecting pluripotent hematopioetic progenitor cells |
US6001585A (en) * | 1997-11-14 | 1999-12-14 | Cellex Biosciences, Inc. | Micro hollow fiber bioreactor |
US6946291B2 (en) * | 1998-04-24 | 2005-09-20 | University Hospitals Of Cleveland | Mixed cell diagnostic systems |
US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
US6662805B2 (en) * | 1999-03-24 | 2003-12-16 | The Johns Hopkins University | Method for composite cell-based implants |
US6485947B1 (en) * | 1999-05-21 | 2002-11-26 | Cargill Dow Polymers, Llc | Production of lactate using crabtree negative organisms in varying culture conditions |
US6294392B1 (en) * | 1999-07-21 | 2001-09-25 | The Regents Of The University Of California | Spatially-encoded analyte detection |
EP1227823A2 (en) * | 1999-10-20 | 2002-08-07 | Stem Cells, Inc. | Methods for inducing (in vivo) proliferation and migration of transplanted progenitor cells in the brain |
US20030036194A1 (en) | 2001-07-06 | 2003-02-20 | Chunhui Xu | Mesenchymal cells derived from human embryonic stem cells |
EP1444325A4 (en) | 2001-11-15 | 2006-02-15 | Becton Dickinson Co | METHODS AND DEVICES FOR INTEGRATED DISCOVERY OF CELL CULTURE ENVIRONMENTS |
GB0222846D0 (en) | 2002-10-03 | 2002-11-06 | Choo Yen | Cell culture |
US20050154534A1 (en) | 2004-01-13 | 2005-07-14 | Becton, Dickinson And Company | Automated media optimization technology |
GB0517382D0 (en) * | 2005-08-26 | 2005-10-05 | Plasticell Ltd | Cell culture |
US8066472B2 (en) | 2007-11-06 | 2011-11-29 | United Technologies Corporation | Method and apparatus for fan shaft bearing lubrication |
WO2009116951A2 (en) * | 2008-03-17 | 2009-09-24 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
JP2012520672A (ja) * | 2009-03-20 | 2012-09-10 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | マイクロキャリアー上の多能性(pluripotent)および多分化能(multipotent)細胞の培養 |
-
2002
- 2002-10-03 GB GBGB0222846.8A patent/GB0222846D0/en not_active Ceased
-
2003
- 2003-10-03 CN CN201210290805.5A patent/CN103205393B/zh not_active Expired - Lifetime
- 2003-10-03 SG SG200702446-6A patent/SG155050A1/en unknown
- 2003-10-03 JP JP2004540980A patent/JP4820091B2/ja not_active Expired - Lifetime
- 2003-10-03 US US10/530,128 patent/US8114669B2/en active Active
- 2003-10-03 ES ES03753734T patent/ES2307969T3/es not_active Expired - Lifetime
- 2003-10-03 PT PT03753734T patent/PT1551954E/pt unknown
- 2003-10-03 CN CN2003801047700A patent/CN1720323B/zh not_active Expired - Lifetime
- 2003-10-03 AU AU2003271896A patent/AU2003271896B2/en not_active Expired
- 2003-10-03 CA CA2501280A patent/CA2501280C/en not_active Expired - Lifetime
- 2003-10-03 EP EP03753734A patent/EP1551954B1/en not_active Expired - Lifetime
- 2003-10-03 DE DE60321585T patent/DE60321585D1/de not_active Expired - Lifetime
- 2003-10-03 WO PCT/GB2003/004287 patent/WO2004031369A1/en active IP Right Grant
- 2003-10-03 AT AT03753734T patent/ATE398170T1/de active
- 2003-10-03 DK DK03753734T patent/DK1551954T3/da active
- 2003-10-03 EP EP20080007504 patent/EP1985696B1/en not_active Expired - Lifetime
- 2003-10-03 DK DK08007504.7T patent/DK1985696T3/en active
-
2008
- 2008-09-10 CY CY20081100975T patent/CY1108329T1/el unknown
-
2011
- 2011-07-14 JP JP2011155433A patent/JP5603300B2/ja not_active Expired - Lifetime
- 2011-10-18 US US13/276,172 patent/US20120088302A1/en not_active Abandoned
-
2013
- 2013-04-05 US US13/857,888 patent/US9574174B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
SG155050A1 (en) | 2009-09-30 |
US20120088302A1 (en) | 2012-04-12 |
JP2006500941A (ja) | 2006-01-12 |
JP5603300B2 (ja) | 2014-10-08 |
US9574174B2 (en) | 2017-02-21 |
EP1985696A1 (en) | 2008-10-29 |
CA2501280A1 (en) | 2004-04-15 |
CN1720323A (zh) | 2006-01-11 |
US20070298411A1 (en) | 2007-12-27 |
CA2501280C (en) | 2013-12-03 |
CN103205393B (zh) | 2017-04-12 |
DK1551954T3 (da) | 2008-10-06 |
JP4820091B2 (ja) | 2011-11-24 |
ES2307969T3 (es) | 2008-12-01 |
US20130337529A1 (en) | 2013-12-19 |
PT1551954E (pt) | 2008-09-01 |
ATE398170T1 (de) | 2008-07-15 |
EP1985696B1 (en) | 2015-05-20 |
EP1551954B1 (en) | 2008-06-11 |
GB0222846D0 (en) | 2002-11-06 |
EP1551954A1 (en) | 2005-07-13 |
AU2003271896A1 (en) | 2004-04-23 |
CN1720323B (zh) | 2012-12-19 |
AU2003271896B2 (en) | 2008-08-21 |
US8114669B2 (en) | 2012-02-14 |
CN103205393A (zh) | 2013-07-17 |
JP2011250791A (ja) | 2011-12-15 |
WO2004031369A1 (en) | 2004-04-15 |
DK1985696T3 (en) | 2015-08-24 |
DE60321585D1 (de) | 2008-07-24 |
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