CY1107733T1 - Μεθοδος για τον χαρακτηρισμο μιας βιολογικης καταστασης χρησιμοποιωντας βαθμοnομημενα προφιλ γονιδιακης εκφρασης - Google Patents

Μεθοδος για τον χαρακτηρισμο μιας βιολογικης καταστασης χρησιμοποιωντας βαθμοnομημενα προφιλ γονιδιακης εκφρασης

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Publication number
CY1107733T1
CY1107733T1 CY20071101178T CY071101178T CY1107733T1 CY 1107733 T1 CY1107733 T1 CY 1107733T1 CY 20071101178 T CY20071101178 T CY 20071101178T CY 071101178 T CY071101178 T CY 071101178T CY 1107733 T1 CY1107733 T1 CY 1107733T1
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CY
Cyprus
Prior art keywords
data set
profile data
graduate
characterizing
panel
Prior art date
Application number
CY20071101178T
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English (en)
Inventor
Victor Tryon
Michael P Belilacqua
Danute M Bankaitis-Davis
John Cheronis
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Source Precision Medicine, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26839213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1107733(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Source Precision Medicine, Inc. filed Critical Source Precision Medicine, Inc.
Publication of CY1107733T1 publication Critical patent/CY1107733T1/el

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Urology & Nephrology (AREA)
  • Theoretical Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Η εφεύρεση παρέχει μία μέθοδο, για την αξιολόγηση μίας βιολογικής κατάστασης ενός υποκειμένου, η οποία περιλαμβάνει: α. τη λήψη από το υποκείμενο ενός δείγματος που έχει τουλάχιστον ένα από RNA και πρωτεΐνες· β. τη λήψη από το δείγμα ενός πρώτου συνόλου δεδομένων προφίλ, όπου το πρώτο σύνολο δεδομένων προφίλ περιλαμβάνει ένα πλήθος μελών, όπου το κάθε μέλος είναι ένα ποσοτικό μέτρο της ποσότητας ενός ξεχωριστού συστατικού RNA ή πρωτεΐνης σε ένα πάνελ συστατικών που επιλέγεται έτσι που η μέτρηση των συστατικών επιτρέπει τη μέτρηση της βιολογικής κατάστασης· και γ. την παραγωγή ενός βαθμονομημένου συνόλου δεδομένων προφίλ για το πάνελ, όπου κάθε μέλος του βαθμονομημένου συνόλου δεδομένων προφίλ είναι μία συνάρτηση ενός αντίστοιχου μέλους του πρώτου συνόλου δεδομένων προφίλ και ενός αντίστοιχου μέλους ενός συνόλου δεδομένων προφίλ βάσης για το πάνελ, όπου το βαθμονομημένο σύνολο δεδομένων προφίλ παρέχει ένα μέτρο της βιολογικής κατάστασης του υποκειμένου.
CY20071101178T 1999-06-28 2007-09-12 Μεθοδος για τον χαρακτηρισμο μιας βιολογικης καταστασης χρησιμοποιωντας βαθμοnομημενα προφιλ γονιδιακης εκφρασης CY1107733T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14154299P 1999-06-28 1999-06-28
US19552200P 2000-04-07 2000-04-07
EP00944977A EP1198585B1 (en) 1999-06-28 2000-06-28 Method for characterizing a biological condition using calibrated gene expression profiles

Publications (1)

Publication Number Publication Date
CY1107733T1 true CY1107733T1 (el) 2013-04-18

Family

ID=26839213

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071101178T CY1107733T1 (el) 1999-06-28 2007-09-12 Μεθοδος για τον χαρακτηρισμο μιας βιολογικης καταστασης χρησιμοποιωντας βαθμοnομημενα προφιλ γονιδιακης εκφρασης

Country Status (13)

Country Link
EP (1) EP1198585B1 (el)
JP (1) JP2004528526A (el)
KR (1) KR20020079364A (el)
AT (1) ATE364721T1 (el)
AU (1) AU784233B2 (el)
CA (1) CA2378008A1 (el)
CY (1) CY1107733T1 (el)
DE (1) DE60035196T2 (el)
DK (1) DK1198585T3 (el)
ES (1) ES2290046T3 (el)
IL (2) IL147349A0 (el)
PT (1) PT1198585E (el)
WO (1) WO2001025473A1 (el)

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US7473528B2 (en) 1999-01-06 2009-01-06 Genenews Inc. Method for the detection of Chagas disease related gene transcripts in blood
US6960439B2 (en) 1999-06-28 2005-11-01 Source Precision Medicine, Inc. Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
US7590493B2 (en) 2000-07-31 2009-09-15 Ocimum Biosolutions, Inc. Methods for determining hepatotoxins
AUPR480901A0 (en) * 2001-05-04 2001-05-31 Genomics Research Partners Pty Ltd Diagnostic method for assessing a condition of a performance animal
CA2447357A1 (en) * 2001-05-22 2002-11-28 Gene Logic, Inc. Molecular toxicology modeling
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7235358B2 (en) 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US20030096264A1 (en) * 2001-06-18 2003-05-22 Psychiatric Genomics, Inc. Multi-parameter high throughput screening assays (MPHTS)
US7447594B2 (en) 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
JP2005517400A (ja) * 2001-07-10 2005-06-16 ジーン ロジック インコーポレイテッド 心臓毒分子毒性モデリング
EP1427810B9 (en) * 2001-08-21 2012-04-25 Ventana Medical Systems, Inc. Method and quantification assay for determining c-kit/scf/pakt status
KR20040064275A (ko) 2001-11-09 2004-07-16 소스 프리시전 메디슨, 인코포레이티드 유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인
US7469185B2 (en) 2002-02-04 2008-12-23 Ocimum Biosolutions, Inc. Primary rat hepatocyte toxicity modeling
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US7662594B2 (en) 2002-09-20 2010-02-16 New England Biolabs, Inc. Helicase-dependent amplification of RNA
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JP2006510382A (ja) * 2002-12-19 2006-03-30 ソース プレシジョン メディスン， インコーポレイテッド 遺伝子発現プロフィールを用いる、感染症の同定、モニタリング、および処置、ならびに感染症に関連する炎症状態の特徴付け
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US7519519B1 (en) 2002-12-20 2009-04-14 Entelos, Inc. Signature projection score
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WO2005087924A1 (ja) * 2004-02-18 2005-09-22 Mie Tlo Co., Ltd. Ｄｎａチップ並びに疾患関連遺伝子の抽出方法
AU2006259306B2 (en) 2005-06-16 2012-02-16 Life Technologies Corporation Gene expression profiling for identification and monitoring of multiple sclerosis
EP1945814A2 (en) 2005-09-27 2008-07-23 Source MDX Gene expression profiling for identification monitoring and treatment of rheumatoid arthritis
WO2007136728A2 (en) * 2006-05-16 2007-11-29 Source Mdx Assessment of effect of an agent on a human biological condition using rodent gene expression panels
US20100196889A1 (en) 2006-11-13 2010-08-05 Bankaitis-Davis Danute M Gene Expression Profiling for Identification, Monitoring and Treatment of Colorectal Cancer
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Also Published As

Publication number Publication date
PT1198585E (pt) 2007-09-20
ES2290046T3 (es) 2008-02-16
JP2004528526A (ja) 2004-09-16
EP1198585B1 (en) 2007-06-13
ATE364721T1 (de) 2007-07-15
EP1198585A1 (en) 2002-04-24
AU784233B2 (en) 2006-02-23
DE60035196D1 (de) 2007-07-26
IL147349A0 (en) 2002-08-14
CA2378008A1 (en) 2001-04-12
WO2001025473A1 (en) 2001-04-12
IL147349A (en) 2011-12-29
WO2001025473A9 (en) 2002-08-08
KR20020079364A (ko) 2002-10-19
DE60035196T2 (de) 2008-02-21
AU5898500A (en) 2001-05-10
DK1198585T3 (da) 2007-10-15

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