CY1106876T1 - Συσκευασια και μεθοδος ανιχνευσεως της πρωτεϊνης esm-1 - Google Patents
Συσκευασια και μεθοδος ανιχνευσεως της πρωτεϊνης esm-1Info
- Publication number
- CY1106876T1 CY1106876T1 CY20071101200T CY071101200T CY1106876T1 CY 1106876 T1 CY1106876 T1 CY 1106876T1 CY 20071101200 T CY20071101200 T CY 20071101200T CY 071101200 T CY071101200 T CY 071101200T CY 1106876 T1 CY1106876 T1 CY 1106876T1
- Authority
- CY
- Cyprus
- Prior art keywords
- esm
- amino acid
- packaging
- protection
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
Η εφεύρεση αφορά ένα κυτίο ή συσκευασία για την ανίχνευση της πρωτεΐνης ESM-1 σε ένα δείγμα, περιλαμβάνουσα: a) ένα πρώτο αντίσωμα συνδεόμενο επιλεκτικά με τη Ν-τερματική περιοχή της πρωτεΐνης ESM-1 που περιλαμβάνεται μεταξύ του αμινοξέως στη θέση 1 και του αμινοξέως στη θέση 78 της αλληλουχίας αμινοξέων της εν λόγω πρωτεΐνης· και b) ένα δεύτερο αντίσωμα συνδεόμενο επιλεκτικά στη C-τερματική περιοχή που περιλαμβάνεται μεταξύ του αμινοξέως στη θέση 79 και του αμινοξέως στη θέση 184 της αλληλουχίας αμινοξέων της πρωτεΐνης ESM-1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0014421A FR2816410B1 (fr) | 2000-11-09 | 2000-11-09 | Necessaire de detection de la proteine esm-1 et procede de detection mettant en oeuvre ledit necessaire |
EP01993830A EP1336109B1 (fr) | 2000-11-09 | 2001-11-08 | Trousse et procede de detection de la proteine esm-1 |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1106876T1 true CY1106876T1 (el) | 2012-09-26 |
Family
ID=8856264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20071101200T CY1106876T1 (el) | 2000-11-09 | 2007-09-17 | Συσκευασια και μεθοδος ανιχνευσεως της πρωτεϊνης esm-1 |
Country Status (13)
Country | Link |
---|---|
US (1) | US7473564B2 (el) |
EP (1) | EP1336109B1 (el) |
JP (1) | JP4290424B2 (el) |
AT (1) | ATE366420T1 (el) |
AU (1) | AU2002223044A1 (el) |
CA (1) | CA2428368A1 (el) |
CY (1) | CY1106876T1 (el) |
DE (1) | DE60129239T2 (el) |
DK (1) | DK1336109T3 (el) |
ES (1) | ES2290193T3 (el) |
FR (1) | FR2816410B1 (el) |
PT (1) | PT1336109E (el) |
WO (1) | WO2002039123A1 (el) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030091574A1 (en) * | 2001-03-23 | 2003-05-15 | Gevas Philip C. | Combination treatment of pancreatic cancer |
US20090191232A1 (en) * | 2001-05-04 | 2009-07-30 | Gevas Philip C | Combination therapy for the treatment of tumors |
CA2450898A1 (en) * | 2001-07-09 | 2003-01-23 | Aphton Corporation | Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus |
WO2004003172A2 (en) * | 2002-07-01 | 2004-01-08 | Pharmacia Corporation | Esm-1 gene differentially expressed in angiogenesis, antagonists thereof, and methods of using the same |
US7235376B2 (en) * | 2003-03-28 | 2007-06-26 | Receptor Biologix, Inc. | Gastrin hormone immunoassays |
JP2007524144A (ja) | 2003-06-18 | 2007-08-23 | フジツー シーメンス コンピュータース ゲゼルシャフト ミット ベシュレンクテル ハフツング | クラスタ装置 |
WO2005095459A2 (en) * | 2004-03-29 | 2005-10-13 | Receptor Biologix, Inc. | Monoclonal antibodies to gastrin hormone |
DK1794586T3 (da) * | 2004-09-22 | 2013-05-13 | Cancer Advances Inc | Monoklonale antistoffer til progastrin |
ES2316293B1 (es) * | 2007-07-27 | 2010-02-05 | Institut De Reserca Hospital Universitari Vall D'hebron | Metodo para detectar una disfuncion endotelial. |
KR101058753B1 (ko) * | 2007-11-22 | 2011-08-24 | 한국생명공학연구원 | 대장암 마커로서의 esm-1 유전자 및 이를 이용한대장암의 진단 및 치료에의 용도 |
WO2010040538A1 (en) * | 2008-10-08 | 2010-04-15 | Inserm (Institut National De La Santé Et De La Recherche Medicale) | Marker peptides for determining the occurrence of an inflammatory state in a subject |
RU2589903C2 (ru) * | 2011-01-21 | 2016-07-10 | Инсерм (Энститю Насьональ Де Ля Сантэ Э Де Ля Решерш Медикаль) | Способы и наборы для прогнозирования риска дыхательной недостаточности, почечной недостаточности или тромбопении у пациента, страдающего сепсисом, путем измерения уровней эндокана в крови |
WO2014135488A1 (en) * | 2013-03-04 | 2014-09-12 | Iq Products B.V. | Prognostic marker to determine the risk for early-onset preeclampsia |
TWI772927B (zh) * | 2015-03-31 | 2022-08-01 | 德商英麥提克生物技術股份有限公司 | 用於腎細胞癌(rcc)免疫治療的新型肽和肽組合物和支架 |
ES2817087T3 (es) | 2016-08-04 | 2021-04-06 | Hoffmann La Roche | ESM-1 (endocan) circulante en la evaluación de la fibrilación auricular |
CN116097099A (zh) | 2020-08-14 | 2023-05-09 | 豪夫迈·罗氏有限公司 | 用于评定无症状脑梗死和认知衰退的esm-1 |
FR3135892B1 (fr) | 2022-05-30 | 2024-06-14 | Biothelis | traitement d’un syndrome de détresse respiratoire aiguë (SDRA) chez un patient |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5506111A (en) * | 1989-02-10 | 1996-04-09 | Teijin Limited | Method of immunological assaying of human osteocalcin, reagent and kit therefor, antibody to human osteocalcin, hybridoma producing said antibody, and method of producing it |
US5747280A (en) | 1995-06-05 | 1998-05-05 | Human Genome Sciences, Inc. | Human vascular IBP-like growth factor |
WO1996017931A1 (en) | 1994-12-09 | 1996-06-13 | Human Genome Sciences, Inc. | Human vascular ibp-like growth factor |
US6670328B1 (en) * | 1997-06-24 | 2003-12-30 | Institut Pasteur De Lille | Proteins and peptides derived from protein ESM-1 and their uses in the treatment and diagnosis of diseases linked to leukocyte migration |
FR2775691B1 (fr) * | 1998-03-05 | 2000-12-15 | Pasteur Institut | Anticorps monoclonaux specifiques de la proteine esm-1, et utilisation de ces anticorps pour la detection de la proteine esm-1 |
-
2000
- 2000-11-09 FR FR0014421A patent/FR2816410B1/fr not_active Expired - Fee Related
-
2001
- 2001-11-08 PT PT01993830T patent/PT1336109E/pt unknown
- 2001-11-08 AU AU2002223044A patent/AU2002223044A1/en not_active Abandoned
- 2001-11-08 US US10/416,204 patent/US7473564B2/en not_active Expired - Lifetime
- 2001-11-08 DE DE60129239T patent/DE60129239T2/de not_active Expired - Lifetime
- 2001-11-08 JP JP2002541397A patent/JP4290424B2/ja not_active Expired - Fee Related
- 2001-11-08 WO PCT/FR2001/003477 patent/WO2002039123A1/fr active IP Right Grant
- 2001-11-08 AT AT01993830T patent/ATE366420T1/de active
- 2001-11-08 EP EP01993830A patent/EP1336109B1/fr not_active Expired - Lifetime
- 2001-11-08 DK DK01993830T patent/DK1336109T3/da active
- 2001-11-08 CA CA002428368A patent/CA2428368A1/fr not_active Abandoned
- 2001-11-08 ES ES01993830T patent/ES2290193T3/es not_active Expired - Lifetime
-
2007
- 2007-09-17 CY CY20071101200T patent/CY1106876T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
FR2816410A1 (fr) | 2002-05-10 |
ES2290193T3 (es) | 2008-02-16 |
US7473564B2 (en) | 2009-01-06 |
PT1336109E (pt) | 2007-09-24 |
DE60129239T2 (de) | 2008-03-13 |
AU2002223044A1 (en) | 2002-05-21 |
ATE366420T1 (de) | 2007-07-15 |
WO2002039123A1 (fr) | 2002-05-16 |
CA2428368A1 (fr) | 2002-05-16 |
JP2004522941A (ja) | 2004-07-29 |
DE60129239D1 (de) | 2007-08-16 |
EP1336109B1 (fr) | 2007-07-04 |
EP1336109A1 (fr) | 2003-08-20 |
JP4290424B2 (ja) | 2009-07-08 |
FR2816410B1 (fr) | 2003-04-18 |
DK1336109T3 (da) | 2007-10-15 |
US20040063164A1 (en) | 2004-04-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1106876T1 (el) | Συσκευασια και μεθοδος ανιχνευσεως της πρωτεϊνης esm-1 | |
CY1118443T1 (el) | Anti-tnf αντισωματα, συνθεσεις, μεθοδοι και χρησεις | |
CY1115778T1 (el) | Πολλαπλες παραλλαγες της πρωτεϊνης μηνiγγιτιδοκοκκου νμβ1870 | |
UY28641A1 (es) | Anticuerpos | |
CY1117551T1 (el) | Μεθοδος ελεγχου της δραστικοτητας ανοσολογικα λειτουργικου μοριου | |
CY1110689T1 (el) | Συνθεσεις οι οποιες περιλαμβανουν πολυπεπτιδια | |
DK2316852T3 (da) | Stabiliserede enkeltdomæne-antistoffer | |
ATE509120T1 (de) | Fusionsproteine zur detektion von analyten | |
DK1266025T3 (da) | Protein-scaffolds for antistof-mimetika og andre bindingsproteiner | |
CY1108450T1 (el) | Μεθοδος για την ανιχνευση ν-τελικου προβνρ | |
CY1111283T1 (el) | Μορια με παρατεταμενες ημι-περιοδους ζωης, συνθεσεις και χρησεις εξ αυτων | |
CY1107537T1 (el) | Ανaλυση συνδυασμoy hcv αντιγoνου/αντισωματος | |
CY1112330T1 (el) | Πρωτεϊνες συνδεσης gag | |
BR0009206A (pt) | Isolamento e análise de proteina | |
HUP0303134A2 (hu) | HIV-peptidek, antigének, vakcinakészítmények, immunológiai mérési reagenskészletek és eljárás HIV által indukált antitestek detektálására | |
CY1109715T1 (el) | IL-1β ΔΕΣΜΕΥΤΙΚΑ ΑΝΤΙΣΩΜΑΤΑ ΚΑΙ ΘΡΑΥΣΜΑΤΑ ΑΥΤΩΝ | |
CY1113218T1 (el) | Υβριδιο και διμερης εκφραση πρωτεϊνων ναϊσσεριας | |
ES2181674T3 (es) | Dominios de union en las proteinas notch y delta. | |
CY1106532T1 (el) | Ετερολογος εκφραση των πρωτεϊνων της neisseria | |
ATE464374T1 (de) | Assay zum schnellen nachweis vom humanen aktivierten protein c und hochspezifischer monoklonaler antikörper dagegen | |
DE60331677D1 (de) | Kit zur untersuchung von menschlichem niedermolekulargewicht cd14 und antikörper | |
DE50112802D1 (de) | Peptide, deren herstellung und verwendung zur bindung von immunglobulinen | |
ATE489623T1 (de) | Peptide zum nachweis von ehrlichia ewingii antikörper | |
TR200200071T2 (tr) | Prion proteininin belirlenmesi için monoklonal antikorlar ve antikor kokteyli. | |
CY1114402T1 (el) | Διπλα-διαμολυνθεισα κυτταρικη γραμμη χρησιμη για την ταυτοποιηση αναστολεων μεταφορας |