CY1106769T1 - Λυοφιλοποιησιμη φαρμακευτικη συνθεση εικονικου φαρμακου προοριζομενη για τη μιμηση ενος φαρμακου, ειδικα με βαση πρωτεϊνες ή πολυπεπτιδια - Google Patents
Λυοφιλοποιησιμη φαρμακευτικη συνθεση εικονικου φαρμακου προοριζομενη για τη μιμηση ενος φαρμακου, ειδικα με βαση πρωτεϊνες ή πολυπεπτιδιαInfo
- Publication number
- CY1106769T1 CY1106769T1 CY20071101005T CY071101005T CY1106769T1 CY 1106769 T1 CY1106769 T1 CY 1106769T1 CY 20071101005 T CY20071101005 T CY 20071101005T CY 071101005 T CY071101005 T CY 071101005T CY 1106769 T1 CY1106769 T1 CY 1106769T1
- Authority
- CY
- Cyprus
- Prior art keywords
- drug
- pharmaceutical
- pharmaceutical composition
- lyophilisable
- simulation
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title 1
- 238000004088 simulation Methods 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000902 placebo Substances 0.000 abstract 1
- 229940068196 placebo Drugs 0.000 abstract 1
- 150000005846 sugar alcohols Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Η εφεύρεση αφορά μία λυοφιλοποιημένη φαρμακευτική σύνθεση προοριζόμενη για τη μίμηση ενός φαρμάκου, ειδικά με βάση πρωτεΐνες ή πεπτίδια, και η οποία μπορεί να χρησιμεύσει ως εικονικό φάρμακο, χαρακτηριζόμενη από το ότι περιλαμβάνει το σύνηθες έκδοχο του εν λόγω φαρμάκου, μία ή περισσότερες σακχαρο-αλκοόλες υπό κρυσταλλική μορφή και/ή ένα ή περισσότερα αμινοξέα υπό κρυσταλλική μορφή, η οποία σύνθεση παρουσιάζει ωσμωτικότητα περιλαμβανόμενη μεταξύ 250 και 650 mOsm μετά από ανασύσταση υπό τη μορφή διαλύματος. Εφαρμογή στις ενέσιμες μορφές ή σε διαδερμική ή οφθαλμική εφαρμογή.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9711626A FR2768341B1 (fr) | 1997-09-18 | 1997-09-18 | Composition pharmaceutique placebo lyophilisable destinee a imiter un medicament, notamment a base de proteines ou de polypeptides |
| PCT/FR1998/001956 WO1999013866A1 (fr) | 1997-09-18 | 1998-09-14 | Composition pharmaceutique placebo lyophilisable destinee a imiter un medicament, notamment a base de proteines ou de polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1106769T1 true CY1106769T1 (el) | 2012-05-23 |
Family
ID=9511216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20071101005T CY1106769T1 (el) | 1997-09-18 | 2007-07-30 | Λυοφιλοποιησιμη φαρμακευτικη συνθεση εικονικου φαρμακου προοριζομενη για τη μιμηση ενος φαρμακου, ειδικα με βαση πρωτεϊνες ή πολυπεπτιδια |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6242423B1 (el) |
| EP (1) | EP1014948B1 (el) |
| AT (1) | ATE365542T1 (el) |
| CA (1) | CA2304021A1 (el) |
| CY (1) | CY1106769T1 (el) |
| DE (1) | DE69837997T2 (el) |
| DK (1) | DK1014948T3 (el) |
| ES (1) | ES2287980T3 (el) |
| FR (1) | FR2768341B1 (el) |
| PT (1) | PT1014948E (el) |
| WO (1) | WO1999013866A1 (el) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2768341B1 (fr) * | 1997-09-18 | 2000-04-14 | Lab Francais Du Fractionnement | Composition pharmaceutique placebo lyophilisable destinee a imiter un medicament, notamment a base de proteines ou de polypeptides |
| US6566575B1 (en) | 2000-02-15 | 2003-05-20 | 3M Innovative Properties Company | Patterned absorbent article for wound dressing |
| US6977323B1 (en) | 2000-02-17 | 2005-12-20 | 3M Innovative Properties Company | Foam-on-film medical articles |
| US6716186B1 (en) | 2000-08-16 | 2004-04-06 | 3M Innovative Properties Company | Curable adhesive splints and methods |
| US6903243B1 (en) | 2000-09-08 | 2005-06-07 | 3M Innovative Properties Company | Multi-layer absorbent wound dressing |
| US7005143B2 (en) | 2002-04-12 | 2006-02-28 | 3M Innovative Properties Company | Gel materials, medical articles, and methods |
| US7612248B2 (en) | 2002-12-19 | 2009-11-03 | 3M Innovative Properties Company | Absorbent medical articles |
| US20050070688A1 (en) | 2003-09-26 | 2005-03-31 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| US7384984B2 (en) | 2003-12-10 | 2008-06-10 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| US7074839B2 (en) | 2004-03-01 | 2006-07-11 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from reactive oligomers having pendent photoinitiator groups |
| US7342047B2 (en) * | 2004-03-02 | 2008-03-11 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from reactive oligomers having pendent unsaturated groups |
| US7335690B2 (en) | 2005-01-25 | 2008-02-26 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from polymers having pendent Michael donor groups |
| US8609131B2 (en) | 2005-01-25 | 2013-12-17 | 3M Innovative Properties Company | Absorbent dressing comprising hydrophilic polymer prepared via Michael reaction |
| US7981949B2 (en) | 2006-05-23 | 2011-07-19 | 3M Innovative Properties Company | Curable hydrophilic compositions |
| US20110155620A1 (en) | 2009-12-30 | 2011-06-30 | Baxter International Inc. | Rapid reconstitution for lyophilized-pharmaceutical suspensions |
| WO2023183542A2 (en) * | 2022-03-25 | 2023-09-28 | Amgen Inc. | Artificial lyophilized product samples for automated visual inspection systems |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5151511A (en) * | 1974-10-25 | 1976-05-07 | Tooru Tatsuhara | Aminosanseizai no anteikaho |
| EP0084705B1 (en) * | 1981-12-11 | 1987-01-14 | JOHN WYETH & BROTHER LIMITED | Process for preparing solid shaped articles |
| IL78930A0 (en) * | 1985-07-29 | 1986-09-30 | Abbott Lab | Lyophilized emulsion compositions for parenteral administration |
| FR2719479B1 (fr) * | 1994-05-04 | 1996-07-26 | Sanofi Elf | Formulation stable lyophilisée comprenant une protéine: kit de dosage. |
| FR2751177B1 (fr) * | 1996-07-17 | 1998-08-28 | Morelle Jean | Compositions exemptes de proteines et de peptides obtenues a partir de toutes proteines animales, destinees a l'alimentation animale et humaine, ainsi qu'a l'usage cosmetique pharmaceutique et agricole |
| FR2768341B1 (fr) * | 1997-09-18 | 2000-04-14 | Lab Francais Du Fractionnement | Composition pharmaceutique placebo lyophilisable destinee a imiter un medicament, notamment a base de proteines ou de polypeptides |
-
1997
- 1997-09-18 FR FR9711626A patent/FR2768341B1/fr not_active Expired - Fee Related
-
1998
- 1998-09-14 DE DE69837997T patent/DE69837997T2/de not_active Expired - Lifetime
- 1998-09-14 PT PT98943975T patent/PT1014948E/pt unknown
- 1998-09-14 DK DK98943975T patent/DK1014948T3/da active
- 1998-09-14 CA CA002304021A patent/CA2304021A1/fr not_active Abandoned
- 1998-09-14 US US09/508,831 patent/US6242423B1/en not_active Expired - Fee Related
- 1998-09-14 WO PCT/FR1998/001956 patent/WO1999013866A1/fr active IP Right Grant
- 1998-09-14 ES ES98943975T patent/ES2287980T3/es not_active Expired - Lifetime
- 1998-09-14 AT AT98943975T patent/ATE365542T1/de active
- 1998-09-14 EP EP98943975A patent/EP1014948B1/fr not_active Expired - Lifetime
-
2007
- 2007-07-30 CY CY20071101005T patent/CY1106769T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69837997D1 (de) | 2007-08-09 |
| ES2287980T3 (es) | 2007-12-16 |
| DE69837997T2 (de) | 2008-02-28 |
| FR2768341A1 (fr) | 1999-03-19 |
| EP1014948B1 (fr) | 2007-06-27 |
| FR2768341B1 (fr) | 2000-04-14 |
| EP1014948A1 (fr) | 2000-07-05 |
| PT1014948E (pt) | 2007-07-18 |
| DK1014948T3 (da) | 2007-09-24 |
| US6242423B1 (en) | 2001-06-05 |
| WO1999013866A1 (fr) | 1999-03-25 |
| CA2304021A1 (fr) | 1999-03-25 |
| ATE365542T1 (de) | 2007-07-15 |
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