CY1106201T1 - Αναλογα δισκοδepμολιδης και η φαρμακευτικη τους χρηση - Google Patents
Αναλογα δισκοδepμολιδης και η φαρμακευτικη τους χρησηInfo
- Publication number
- CY1106201T1 CY1106201T1 CY20061101483T CY061101483T CY1106201T1 CY 1106201 T1 CY1106201 T1 CY 1106201T1 CY 20061101483 T CY20061101483 T CY 20061101483T CY 061101483 T CY061101483 T CY 061101483T CY 1106201 T1 CY1106201 T1 CY 1106201T1
- Authority
- CY
- Cyprus
- Prior art keywords
- discodepmolide
- analogues
- pharmaceutical use
- formula
- specific
- Prior art date
Links
- AADVCYNFEREWOS-OBRABYBLSA-N Discodermolide Chemical class C=C\C=C/[C@H](C)[C@H](OC(N)=O)[C@@H](C)[C@H](O)[C@@H](C)C\C(C)=C/[C@H](C)[C@@H](O)[C@@H](C)\C=C/[C@@H](O)C[C@@H]1OC(=O)[C@H](C)[C@@H](O)[C@H]1C AADVCYNFEREWOS-OBRABYBLSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33239901P | 2001-11-16 | 2001-11-16 | |
| US34339401P | 2001-12-21 | 2001-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1106201T1 true CY1106201T1 (el) | 2011-06-08 |
Family
ID=26988201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061101483T CY1106201T1 (el) | 2001-11-16 | 2006-10-16 | Αναλογα δισκοδepμολιδης και η φαρμακευτικη τους χρηση |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6833367B2 (https=) |
| EP (1) | EP1312608B1 (https=) |
| JP (1) | JP4410986B2 (https=) |
| AT (1) | ATE334977T1 (https=) |
| CY (1) | CY1106201T1 (https=) |
| DE (1) | DE60213541T2 (https=) |
| DK (1) | DK1312608T3 (https=) |
| ES (1) | ES2267928T3 (https=) |
| PT (1) | PT1312608E (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005084349A2 (en) * | 2004-03-02 | 2005-09-15 | Kosan Biosciences, Inc. | Compounds useful for the synthesis of (+)-discodermolide and methods therefor |
| US7214708B2 (en) * | 2004-11-18 | 2007-05-08 | Kosan Biosciences Incorporated | Synthetic discodermolide analogs |
| FR2951720B1 (fr) * | 2009-10-28 | 2011-12-16 | Pf Medicament | Molecules polyketides comme agents anticancereux |
| JP5822169B2 (ja) * | 2010-07-01 | 2015-11-24 | ユーハン・コーポレイションＹＵＨＡＮ Ｃｏｒｐｏｒａｔｉｏｎ | ＨＭＧ−ＣｏＡ還元酵素阻害剤及びその中間体の製造方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5010099A (en) * | 1989-08-11 | 1991-04-23 | Harbor Branch Oceanographic Institution, Inc. | Discodermolide compounds, compositions containing same and method of preparation and use |
| US5681847A (en) * | 1995-12-05 | 1997-10-28 | Harbor Branch Oceanographic Institution, Inc. | Methods of using discodermolide compounds |
| US6242616B1 (en) * | 1996-12-03 | 2001-06-05 | The Trustees Of The University Of Pennsylvania | Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives |
| US6870058B2 (en) | 1996-12-03 | 2005-03-22 | The Trustees Of The University Of Pennsylvania | Compounds which mimic the chemical and biological properties of discodermolide |
| US6096904A (en) * | 1996-12-03 | 2000-08-01 | The Trustees Of The University Of Pennsylvania | Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives |
| US5789605A (en) | 1996-12-03 | 1998-08-04 | Trustees Of The University Of Pennsylvania | Synthetic techniques and intermediates for polyhydroxy, dienyl lactones and mimics thereof |
| US6127406A (en) * | 1998-10-09 | 2000-10-03 | Harbor Branch Oceanographic Institution, Inc. | Discodermolide compounds and methods of use |
| DE60108359T2 (de) * | 2000-03-01 | 2005-12-22 | Harbor Branch Oceanographic Institution, Inc., Fort Pierce | Biologisch wirksame, analoge verbindungen von discodermoliden |
-
2002
- 2002-11-12 US US10/292,134 patent/US6833367B2/en not_active Expired - Fee Related
- 2002-11-15 EP EP02025728A patent/EP1312608B1/en not_active Expired - Lifetime
- 2002-11-15 ES ES02025728T patent/ES2267928T3/es not_active Expired - Lifetime
- 2002-11-15 JP JP2002332243A patent/JP4410986B2/ja not_active Expired - Fee Related
- 2002-11-15 DE DE60213541T patent/DE60213541T2/de not_active Expired - Lifetime
- 2002-11-15 AT AT02025728T patent/ATE334977T1/de not_active IP Right Cessation
- 2002-11-15 DK DK02025728T patent/DK1312608T3/da active
- 2002-11-15 PT PT02025728T patent/PT1312608E/pt unknown
-
2004
- 2004-09-29 US US10/952,950 patent/US7148218B2/en not_active Expired - Fee Related
-
2006
- 2006-10-16 CY CY20061101483T patent/CY1106201T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003160575A (ja) | 2003-06-03 |
| DK1312608T3 (da) | 2006-11-27 |
| US20050080080A1 (en) | 2005-04-14 |
| US7148218B2 (en) | 2006-12-12 |
| US20030153601A1 (en) | 2003-08-14 |
| ES2267928T3 (es) | 2007-03-16 |
| EP1312608A2 (en) | 2003-05-21 |
| EP1312608B1 (en) | 2006-08-02 |
| PT1312608E (pt) | 2006-12-29 |
| JP4410986B2 (ja) | 2010-02-10 |
| US6833367B2 (en) | 2004-12-21 |
| ATE334977T1 (de) | 2006-08-15 |
| EP1312608A3 (en) | 2003-06-18 |
| DE60213541D1 (de) | 2006-09-14 |
| DE60213541T2 (de) | 2007-10-04 |
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