CU23771A3 - Mejoramiento de la producción microbiana de etanol - Google Patents

Mejoramiento de la producción microbiana de etanol

Info

Publication number
CU23771A3
CU23771A3 CU20080180A CU20080180A CU23771A3 CU 23771 A3 CU23771 A3 CU 23771A3 CU 20080180 A CU20080180 A CU 20080180A CU 20080180 A CU20080180 A CU 20080180A CU 23771 A3 CU23771 A3 CU 23771A3
Authority
CU
Cuba
Prior art keywords
nad
formate
dehydrogenase
gene
linked
Prior art date
Application number
CU20080180A
Other languages
English (en)
Inventor
Namdar Baghaei-Yazdi
Muhammad Javed
Original Assignee
Bioconversion Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36384080&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CU23771(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bioconversion Technologies Ltd filed Critical Bioconversion Technologies Ltd
Publication of CU23771A3 publication Critical patent/CU23771A3/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Un microorganismo termofílico que carece de la actividad de la lactato deshidrogenasa y de preferencia contiene una trayectoria de piruvato formiato liasa activa. El microorganismo termofílico contiene un gen que codifica una formiato deshidrogenasa enlazada a NAD. El gen que codifica una formiato deshidrogenasa enlazada a NAD es de preferencia una versión de codón optimizada del gen que codifica una formiato deshidrogenasa enlazada a NAD termoestable. Las construcciones de ADN permiten la expresión estable del gen que codifica una formiato deshidrogenasa enlazada a NAD en el microorganismo termofílico. Las construcciones de ADN se basan en el uso de una secuencia de inserción para lograr la expresión estable o recombinación para insertar el gen que codifica una formiato deshidrogenasa enlazada a NAD en el gen de la lactato deshidrogenasa, logrando así la inacticación genética y una nueva funcionalidad en una etapa sencilla. Los microorganismos son útiles en la fermentación de azúcares para producir etanol.
CU20080180A 2006-03-24 2008-09-24 Mejoramiento de la producción microbiana de etanol CU23771A3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0605890.3A GB0605890D0 (en) 2006-03-24 2006-03-24 Enhancemeny Of Microbial Ethanol Production

Publications (1)

Publication Number Publication Date
CU23771A3 true CU23771A3 (es) 2012-02-15

Family

ID=36384080

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20080180A CU23771A3 (es) 2006-03-24 2008-09-24 Mejoramiento de la producción microbiana de etanol

Country Status (18)

Country Link
US (1) US20090226992A1 (es)
EP (1) EP2007897B1 (es)
JP (1) JP2009529905A (es)
CN (1) CN101448948A (es)
AP (1) AP2458A (es)
AU (1) AU2007231208B2 (es)
BR (1) BRPI0709357A2 (es)
CA (1) CA2681380A1 (es)
CU (1) CU23771A3 (es)
DK (1) DK2007897T3 (es)
ES (1) ES2396151T3 (es)
GB (1) GB0605890D0 (es)
MX (1) MX2008012128A (es)
NO (1) NO20084451L (es)
NZ (1) NZ571490A (es)
PL (1) PL2007897T3 (es)
WO (1) WO2007110606A1 (es)
ZA (1) ZA200808380B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2461495A (en) * 2008-02-13 2010-01-06 Bioconversion Technologies Ltd Ethanol production by lactate dehydrogenase-deleted thermophilic microorganisms
GB2457820B (en) 2008-02-28 2010-09-08 Green Biologics Ltd Production process
WO2011024858A1 (ja) * 2009-08-28 2011-03-03 国立大学法人京都大学 海洋バイオマスからのエタノール生産
JP2011167096A (ja) * 2010-02-17 2011-09-01 Kobe Univ バイオマスからのエタノールの生産方法
GB2478791A (en) * 2010-03-19 2011-09-21 Qteros Inc Ethanol production by genetically-modified bacteria
CN102296079A (zh) * 2011-01-18 2011-12-28 浙江大学 耐热型甲酸脱氢酶基因及其编码的多肽
GB2489967A (en) * 2011-04-13 2012-10-17 Ensus Ltd Method of producing an animal feed by hydrolysis and fermentation
CA2850480A1 (en) 2011-09-30 2013-06-20 Mascoma Corporation Engineering microorganisms to increase ethanol production by metabolic redirection
GB201417362D0 (en) 2014-10-01 2014-11-12 Hartley Brian S Devices and methods for selection of microbial strains
KR101976691B1 (ko) * 2017-11-15 2019-05-09 울산과학기술원 재조합 미생물 및 이를 이용한 개미산 제조 방법
CN114540404B (zh) * 2022-02-28 2023-11-07 大连理工大学 一种乙醇发酵过程中二氧化碳原位固定的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8516057D0 (en) * 1985-06-25 1985-07-31 Ciba Geigy Ag Turning device
US5182199A (en) * 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
US6001590A (en) * 1995-09-12 1999-12-14 Kirin Beer Kabushiki Kaisha Promoter and terminator sequences of formate dehydrogenase gene of Candida boidinii
GB0000185D0 (en) * 2000-01-06 2000-03-01 Agrol Limited Ethanol production
GB0011186D0 (en) * 2000-05-09 2000-06-28 Agrol Limited Modification of bacteria
BR0114477A (pt) * 2000-10-06 2004-01-13 Elsworth Biotech Ltd Produção de etanol
US7256016B2 (en) * 2001-11-02 2007-08-14 Rice University Recycling system for manipulation of intracellular NADH availability
US7927859B2 (en) * 2003-08-22 2011-04-19 Rice University High molar succinate yield bacteria by increasing the intracellular NADH availability
WO2007110592A2 (en) * 2006-03-24 2007-10-04 Elsworth Ethanol Company Limited Fermentation process for the production of ethanol
CA2735883C (en) * 2008-09-10 2020-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol

Also Published As

Publication number Publication date
EP2007897A1 (en) 2008-12-31
AU2007231208A1 (en) 2007-10-04
ZA200808380B (en) 2009-11-25
BRPI0709357A2 (pt) 2011-07-12
ES2396151T3 (es) 2013-02-19
MX2008012128A (es) 2008-12-18
EP2007897B1 (en) 2012-09-19
AP2008004642A0 (en) 2008-10-31
WO2007110606A1 (en) 2007-10-04
US20090226992A1 (en) 2009-09-10
AP2458A (en) 2012-09-12
AU2007231208B2 (en) 2012-12-13
NZ571490A (en) 2011-09-30
CN101448948A (zh) 2009-06-03
GB0605890D0 (en) 2006-05-03
DK2007897T3 (da) 2013-01-14
JP2009529905A (ja) 2009-08-27
PL2007897T3 (pl) 2013-04-30
NO20084451L (no) 2008-10-22
CA2681380A1 (en) 2007-10-04

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