CU20220024A7 - Compuestos aromáticos bicíclicos derivatizados por ácido fenilacético y bencilamina, útiles en el tratamiento de trastornos inmunológicos, enfermedades del sistema nervioso central, neurodegenerativas, renales y cardiovasculares - Google Patents

Compuestos aromáticos bicíclicos derivatizados por ácido fenilacético y bencilamina, útiles en el tratamiento de trastornos inmunológicos, enfermedades del sistema nervioso central, neurodegenerativas, renales y cardiovasculares

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CU20220024A7
CU20220024A7 CU2022000024A CU20220024A CU20220024A7 CU 20220024 A7 CU20220024 A7 CU 20220024A7 CU 2022000024 A CU2022000024 A CU 2022000024A CU 20220024 A CU20220024 A CU 20220024A CU 20220024 A7 CU20220024 A7 CU 20220024A7
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CU
Cuba
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useful
treatment
aromatic compounds
bencylamine
neurodegenerative
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CU2022000024A
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English (en)
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Yarlagadda Babu
zhao Dang
Pravin Kotian
peng-cheng Lu
Wei Lv
Krishnan Raman
Andrew Spaulding
Weihe Zhang
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Biocryst Pharm Inc
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Publication of CU20220024A7 publication Critical patent/CU20220024A7/es

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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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Abstract

<p>La presente invención se refiere a compuestos aromáticos bicíclicos de la fórmula (I)</p> <p>ESPACIO PARA LA FÓRMULA</p> <p>y sales farmacéuticamente aceptables de los mismos, que son inhibidores de la actividad enzimática del Factor D, útiles en el tratamiento o la prevención de enfermedades o afecciones que presentan una actividad aberrante del sistema del complemento.</p> <p>Se refiere también a composiciones farmacéuticas que comprenden dichos complejos.</p>
CU2022000024A 2019-10-09 2020-10-09 Compuestos aromáticos bicíclicos derivatizados por ácido fenilacético y bencilamina, útiles en el tratamiento de trastornos inmunológicos, enfermedades del sistema nervioso central, neurodegenerativas, renales y cardiovasculares CU20220024A7 (es)

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US201962912929P 2019-10-09 2019-10-09
PCT/US2020/054992 WO2021072198A1 (en) 2019-10-09 2020-10-09 Oral complement factor d inhibitors

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