CU20150071A7 - Composición de liberación demorada que comprende biguanida - Google Patents
Composición de liberación demorada que comprende biguanidaInfo
- Publication number
- CU20150071A7 CU20150071A7 CUP2015000071A CU20150071A CU20150071A7 CU 20150071 A7 CU20150071 A7 CU 20150071A7 CU P2015000071 A CUP2015000071 A CU P2015000071A CU 20150071 A CU20150071 A CU 20150071A CU 20150071 A7 CU20150071 A7 CU 20150071A7
- Authority
- CU
- Cuba
- Prior art keywords
- biguanida
- understanding
- composition
- delayed release
- delayed
- Prior art date
Links
- 230000003111 delayed effect Effects 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940123208 Biguanide Drugs 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- -1 biguanide compound Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se proporcionan las composiciones y métodos para mejorar la farmacocinética y reducir el riesgo de eventos adversos que resultan de la administración del compuesto de biguanida, que comprende administrar formulaciones de liberación demorada de tales compuestos que tiene una liberación de fase de retardo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361749307P | 2013-01-05 | 2013-01-05 | |
| PCT/US2014/010240 WO2014107617A1 (en) | 2013-01-05 | 2014-01-03 | Delayed-release composition comprising biguanide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20150071A7 true CU20150071A7 (es) | 2016-01-29 |
Family
ID=50030486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CUP2015000071A CU20150071A7 (es) | 2013-01-05 | 2015-07-06 | Composición de liberación demorada que comprende biguanida |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US20140193498A1 (es) |
| EP (2) | EP2941245B1 (es) |
| JP (1) | JP6333855B2 (es) |
| KR (1) | KR102229492B1 (es) |
| CN (2) | CN105101956B (es) |
| AR (1) | AR094374A1 (es) |
| AU (1) | AU2014203942B2 (es) |
| CA (1) | CA2896864C (es) |
| CL (1) | CL2015001914A1 (es) |
| CU (1) | CU20150071A7 (es) |
| EA (1) | EA039530B1 (es) |
| HK (1) | HK1214966A1 (es) |
| IL (1) | IL239722B (es) |
| MX (2) | MX389344B (es) |
| NZ (1) | NZ709525A (es) |
| PH (1) | PH12015501520A1 (es) |
| SG (2) | SG10201705437SA (es) |
| WO (1) | WO2014107617A1 (es) |
| ZA (1) | ZA201504858B (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9480663B2 (en) | 2011-01-07 | 2016-11-01 | Elcelyx Therapeutics, Inc. | Biguanide compositions and methods of treating metabolic disorders |
| US11759441B2 (en) | 2011-01-07 | 2023-09-19 | Anji Pharmaceuticals Inc. | Biguanide compositions and methods of treating metabolic disorders |
| US8796338B2 (en) | 2011-01-07 | 2014-08-05 | Elcelyx Therapeutics, Inc | Biguanide compositions and methods of treating metabolic disorders |
| LT2661266T (lt) | 2011-01-07 | 2020-12-10 | Anji Pharma (Us) Llc | Gydimo būdai chemosensorinio receptoriaus ligando pagrindu |
| US9211263B2 (en) | 2012-01-06 | 2015-12-15 | Elcelyx Therapeutics, Inc. | Compositions and methods of treating metabolic disorders |
| US11974971B2 (en) | 2011-01-07 | 2024-05-07 | Anji Pharmaceuticals Inc. | Compositions and methods for treating metabolic disorders |
| CN110693867A (zh) | 2012-01-06 | 2020-01-17 | 埃尔舍利克斯治疗公司 | 用于治疗代谢性病症的组合物和方法 |
| CN104254325A (zh) | 2012-01-06 | 2014-12-31 | 埃尔舍利克斯治疗公司 | 双胍组合物和治疗代谢性病症的方法 |
| JP6687248B2 (ja) * | 2014-12-24 | 2020-04-22 | プリンシピア バイオファーマ インコーポレイテッド | 回腸−空腸薬物送達用組成物 |
| US10631564B2 (en) | 2015-06-19 | 2020-04-28 | University Of Southern California | Enterically coated microparticle compositions and methods for modified nutrient delivery |
| US10744070B2 (en) | 2015-06-19 | 2020-08-18 | University Of Southern California | Enteral fast access tract platform system |
| EP3568411B1 (en) * | 2017-01-13 | 2024-03-06 | Pietro P. Sanna | Methods and compositions for treating hpa hyperactivity |
| FR3068601B1 (fr) * | 2017-07-05 | 2021-02-19 | Eric Joseph Marie Fulgence Janin | Utilisation de l'imeglimine pour la prevention et/ou le traitement du carcinome hepatocellulaire |
| WO2020247352A1 (en) * | 2019-06-03 | 2020-12-10 | R.P. Scherer Technologies, Llc | Delayed release softgel capsules |
| US12029718B2 (en) | 2021-11-09 | 2024-07-09 | Cct Sciences, Llc | Process for production of essentially pure delta-9-tetrahydrocannabinol |
| US20230000820A1 (en) * | 2021-06-28 | 2023-01-05 | ImmunoMet Therapeutics, Inc. | Solid dosage form of n-1-pyrrolidine-n-5-(3-trifluoromethoxy)phenyl biguanide and uses thereof |
| CN119499228A (zh) | 2023-08-22 | 2025-02-25 | 雅研(天津)生物医药科技中心(有限合伙) | 盐酸二甲双胍肠溶制剂 |
| CN119499203A (zh) | 2023-08-22 | 2025-02-25 | 雅研(天津)生物医药科技中心(有限合伙) | 一种盐酸二甲双胍肠溶片 |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1209253A (en) | 1913-01-09 | 1916-12-19 | Automatic Electric Co | Impulse-transmitting device. |
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| JPS58403B2 (ja) | 1975-07-24 | 1983-01-06 | 武田薬品工業株式会社 | L− アスコルビンサンセイザイノ セイゾウホウ |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| US5135757A (en) | 1988-09-19 | 1992-08-04 | Edward Mendell Co., Inc. | Compressible sustained release solid dosage forms |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| FR2704146B1 (fr) | 1993-04-19 | 1995-07-13 | Cripdom | Microcapsules d'acide acétylsalicylique à libération contrôlée. |
| US5773025A (en) | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| FR2725623A1 (fr) | 1994-10-18 | 1996-04-19 | Flamel Tech Sa | Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os |
| AP2003002729A0 (en) | 1997-04-15 | 2003-06-30 | Csir | Pharmaceutical compositions having appetite suppressant activity |
| US5891919A (en) | 1997-09-19 | 1999-04-06 | Burlington Bio-Medical & Scientific Corp. | Denatonium capsaicinate and methods of producing the same |
| US20040081697A1 (en) * | 1998-11-12 | 2004-04-29 | Smithkline Beecham P.L.C. | Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent |
| ITMI991316A1 (it) | 1999-06-14 | 2000-12-14 | Cip Ninety Two 92 S A | Composizioni farmaceutiche orali a rilascio modificato di mesalazina |
| IL132313A0 (en) | 1999-10-11 | 2001-03-19 | Yeda Res & Dev | Leptin assay |
| US20110217394A1 (en) | 2000-12-05 | 2011-09-08 | Brett Justin West | Iridoid Based Formulations |
| WO2002055009A1 (en) * | 2001-01-12 | 2002-07-18 | Sun Pharmaceutical Industries Limited | Spaced drug delivery system |
| AU2002307217A1 (en) | 2001-03-28 | 2002-10-15 | University Of South Florida | Materials and methods for treatment of cancer and identification of anti-cancer compounds |
| US8030008B2 (en) | 2001-04-05 | 2011-10-04 | Senomyx, Inc. | Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators |
| FR2830447B1 (fr) * | 2001-10-09 | 2004-04-16 | Flamel Tech Sa | Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques |
| US6830759B2 (en) * | 2002-06-28 | 2004-12-14 | Ajinomoto Co., Inc. | Antidiabetic preparation for oral administration |
| US20060019346A1 (en) | 2002-07-29 | 2006-01-26 | Senomyx, Inc. | Identification of a novel bitter taste receptor T2R76 that specifically responds to brucine and prop bitter ligands |
| CA2494281A1 (en) * | 2002-08-02 | 2004-02-12 | Penwest Pharmaceuticals Company | Sustained release formulations of metformin |
| CN1413582A (zh) * | 2002-11-29 | 2003-04-30 | 贵州圣济堂制药有限公司 | 盐酸二甲双胍肠溶片及其制备方法 |
| WO2004055048A2 (en) | 2002-12-18 | 2004-07-01 | Givaudan Sa | Chimeric alpha q-gustducin g-proteins |
| DE10308504A1 (de) | 2003-02-26 | 2004-09-09 | Basf Ag | Enzymatische Herstellung von (Meth)acrylsäureestern |
| US20060172020A1 (en) | 2003-07-17 | 2006-08-03 | Djang Arthur H | Dietary supplement for promoting control of blood-sugar levels and associated pathology in type 2 diabeties |
| EP1737442B1 (en) | 2004-04-20 | 2015-01-07 | Deutsches Institut Für Ernährungsforschung - Stiftung Des Öffentlichen Rechts - Vertreten Durch Den Stiftungsvorstand | Agonists of a bitter taste receptor and uses thereof |
| US20060024335A1 (en) | 2004-07-29 | 2006-02-02 | Roger Stier E | Oral compositions which mask the bitter taste of a bitter-tasting agent |
| WO2006053771A2 (en) | 2004-11-18 | 2006-05-26 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Stiftung Des Öffentlichen Rechts | Agonists of bitter taste receptors and uses thereof |
| US20060222709A1 (en) * | 2005-03-18 | 2006-10-05 | Agi Therapeutics Research Ltd. | Metformin methods and formulations for treating chronic constipation |
| WO2006118341A1 (ja) | 2005-04-28 | 2006-11-09 | Ajinomoto Co., Inc. | 新規ラクタム化合物 |
| US20060269617A1 (en) | 2005-05-26 | 2006-11-30 | Suracell, Inc. | Supplement compositions and method of use for enhancement of insulin sensitivity |
| AU2006262399A1 (en) | 2005-06-22 | 2007-01-04 | Senomyx, Inc. | Identification of human T2R recepors that are activated by bitter molecules in coffee (chlorogenic lactones) and related assays for identifying human bitter taste modulators |
| RU2433821C2 (ru) * | 2005-08-30 | 2011-11-20 | Пирамал Лайф Сайнсис Лимитед | Фармацевтическая композиция метформина с длительным высвобождением и способ ее получения |
| FR2891459B1 (fr) * | 2005-09-30 | 2007-12-28 | Flamel Technologies Sa | Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant |
| US20070104805A1 (en) | 2005-11-01 | 2007-05-10 | Udell Ronald G | Compositions of Hoodia Gordonii and Pinolenic Acid Derivatives |
| JP2007215162A (ja) | 2006-01-11 | 2007-08-23 | Canon Inc | 情報処理装置及びその制御方法、プログラム、記憶媒体 |
| US20070207227A1 (en) | 2006-02-23 | 2007-09-06 | Conopco, Inc., D/B/A Unilever, A Corporation Of New York | Appetite suppressant compositions |
| WO2007116404A2 (en) | 2006-04-10 | 2007-10-18 | Bar-Ilan University | Cucurbitacin glucosides and use thereof in treating cancer |
| CA2551706A1 (en) | 2006-06-27 | 2007-12-27 | Innovative Life Sciences Corporation | Herbal product comprising cinnamon and bitter melon |
| CN100596277C (zh) | 2006-07-10 | 2010-03-31 | 博仲盛景医药技术(北京)有限公司 | 一种促进肠胃蠕动的药物组合物 |
| AU2007286382B2 (en) | 2006-08-17 | 2011-01-20 | Phytopharm Plc | Processes for production of Hoodia plant extracts containing steroidal glycosides |
| CN101505772A (zh) | 2006-08-24 | 2009-08-12 | 荷兰联合利华有限公司 | 制备包含甾体糖苷的组合物的方法 |
| US7811788B2 (en) | 2006-09-05 | 2010-10-12 | Senomyx Inc. | Nucleic acid encoding a haplotype of human T2R receptor hT2R50 |
| EP1975612A1 (en) | 2007-03-29 | 2008-10-01 | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand | Agonists of bitter taste receptors and uses thereof |
| EP1975611A1 (en) | 2007-03-29 | 2008-10-01 | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand | Agonists of bitter taste receptors and uses thereof |
| US20090042813A1 (en) | 2007-08-10 | 2009-02-12 | Sergey Michailovich Melnikov | Hoodia extract oil compositions comprising medium chain triglycerides |
| US20100316736A1 (en) | 2007-10-24 | 2010-12-16 | Desert Labs Agriculture Cooperative Association Ltd. | Appetite suppressant |
| WO2009095993A1 (ja) | 2008-01-29 | 2009-08-06 | Nakamori Pharmaceutical Co., Ltd. | 医薬組成物 |
| EP2306851B1 (en) | 2008-05-23 | 2012-08-01 | Givaudan SA | Bitter alkaloid containing consumables comprising bitter blockers |
| US8546085B2 (en) | 2008-06-13 | 2013-10-01 | Givaudan Sa | Methods of identifying modulators of the bitter taste receptor TAS2R44 |
| ES2550077T3 (es) | 2008-08-29 | 2015-11-04 | Suntory Holdings Limited | Nuevo tetrámero de galato de epigalocatequina y mejorador de la función del endotelio vascular que comprende el mismo |
| WO2010022529A1 (en) | 2008-08-29 | 2010-03-04 | Givaudan Sa | Methods to identify modulators |
| WO2010060198A1 (en) | 2008-11-26 | 2010-06-03 | West Central Envirotech Inc. | Composition and method for controlling insects |
| WO2010076879A1 (ja) | 2009-01-03 | 2010-07-08 | 静岡県公立大学法人 | 硫酸化c-配糖体及びその単離方法並びに合成方法 |
| US8709745B2 (en) | 2009-07-28 | 2014-04-29 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke | Methods for isolating ligands of the human bitter taste receptor TAS2R49 |
| CA2777938C (en) | 2009-10-21 | 2017-11-14 | Wisconsin Alumni Research Foundation | Method of preventing type 1 diabetes |
| PH12012500948A1 (en) | 2009-12-04 | 2013-01-07 | Colgate Palmolive Co | Oral compositions containing extracts of garcinia mangostana l. and related methods |
| EP2345646A1 (en) | 2010-01-14 | 2011-07-20 | InterMed Discovery GmbH | Use of tricyclic sesquiterpene lactones in the treatment of obesity and related diseases and non-therapeutic treatable conditions |
| US20110293753A1 (en) | 2010-05-28 | 2011-12-01 | Louis Bellafiore | Tocotrienol Compositions |
| GB201009873D0 (en) | 2010-06-14 | 2010-07-21 | Univ Leuven Kath | Method for hydrogenation of isoalpha-acids (isohumulones) to hexahydro-iso-alpha-acids (hexahydro-isohumulones) by using heterogeneous ruthenium |
| EP2397039A1 (en) | 2010-06-21 | 2011-12-21 | Abbott Laboratories | Compositions for delaying progression of diabetes using Salacia oblonga extract |
| CN101978956B (zh) * | 2010-10-13 | 2012-03-28 | 北京京丰制药有限公司 | 盐酸二甲双胍肠溶片及其制备方法 |
| LT2661266T (lt) * | 2011-01-07 | 2020-12-10 | Anji Pharma (Us) Llc | Gydimo būdai chemosensorinio receptoriaus ligando pagrindu |
| CN110693867A (zh) * | 2012-01-06 | 2020-01-17 | 埃尔舍利克斯治疗公司 | 用于治疗代谢性病症的组合物和方法 |
| CN103768071B (zh) * | 2012-10-23 | 2016-08-17 | 中国医药工业研究总院 | 一种治疗糖尿病的口服制剂 |
-
2014
- 2014-01-03 HK HK16103014.8A patent/HK1214966A1/zh unknown
- 2014-01-03 CN CN201480003932.XA patent/CN105101956B/zh active Active
- 2014-01-03 EA EA201591085A patent/EA039530B1/ru unknown
- 2014-01-03 KR KR1020157019855A patent/KR102229492B1/ko active Active
- 2014-01-03 NZ NZ709525A patent/NZ709525A/en unknown
- 2014-01-03 CA CA2896864A patent/CA2896864C/en active Active
- 2014-01-03 MX MX2020011594A patent/MX389344B/es unknown
- 2014-01-03 SG SG10201705437SA patent/SG10201705437SA/en unknown
- 2014-01-03 US US14/147,449 patent/US20140193498A1/en not_active Abandoned
- 2014-01-03 WO PCT/US2014/010240 patent/WO2014107617A1/en not_active Ceased
- 2014-01-03 CN CN201910033955.XA patent/CN110051638B/zh active Active
- 2014-01-03 MX MX2015008625A patent/MX376822B/es active IP Right Grant
- 2014-01-03 AU AU2014203942A patent/AU2014203942B2/en active Active
- 2014-01-03 EP EP14702108.3A patent/EP2941245B1/en active Active
- 2014-01-03 EP EP24184490.1A patent/EP4410380A3/en active Pending
- 2014-01-03 JP JP2015551792A patent/JP6333855B2/ja active Active
- 2014-01-03 SG SG11201505240QA patent/SG11201505240QA/en unknown
- 2014-01-06 AR ARP140100044A patent/AR094374A1/es not_active Application Discontinuation
-
2015
- 2015-06-30 IL IL239722A patent/IL239722B/en unknown
- 2015-07-03 PH PH12015501520A patent/PH12015501520A1/en unknown
- 2015-07-03 CL CL2015001914A patent/CL2015001914A1/es unknown
- 2015-07-06 ZA ZA2015/04858A patent/ZA201504858B/en unknown
- 2015-07-06 CU CUP2015000071A patent/CU20150071A7/es unknown
-
2019
- 2019-11-26 US US16/695,498 patent/US20200093750A1/en not_active Abandoned
-
2024
- 2024-05-20 US US18/668,709 patent/US20250000804A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CU20150071A7 (es) | Composición de liberación demorada que comprende biguanida | |
| CO2018000589A2 (es) | Oxiesteroles y composiciones farmacéuticas que los contienen | |
| ECSP19021223A (es) | Derivado de glucagon, conjugado del mismo, composición que comprende el mismo y uso terapéutico del mismo | |
| CL2016001120A1 (es) | Compuestos derivados de pirrolo1,2-f1,2,4triazina ,composición farmacéutica que los comprende y su uso en el tratamiento de una infección por virus sincicial compuestos intermediarios. pct | |
| CO2018000660A2 (es) | Compuestos derivados del (3β)-cholest-5-en-3-alquil-3-ol y (3β)-cholest-3-alquil-3-ol | |
| CU24397B1 (es) | Derivados de piperidinil-indol como inhibidores del factor de complemento b | |
| CU20170077A7 (es) | Compuesto derivado de benzamida sustituida con 1,3-tiazol-2-ilo útil para el tratamiento de trastornos neurogénicos, composiciones y combinaciones que lo comprende | |
| DOP2016000233A (es) | MODULADORES ALOSTÉRICOS DE PROTElNA NÚCLEO DE HEPATITIS B | |
| PH12017502001A1 (en) | Amido-substituted cyclohexane derivatives | |
| CR20160119A (es) | Nuevos compuestos y sus composiciones farmacéuticas para el tratamiento de la fibrosis quística | |
| MX2016002185A (es) | Formulacion combinada de dos compuestos antivirales. | |
| MX2016011810A (es) | Composiciones farmaceuticas de compuestos terapeuticamente activos y sus metodos de uso. | |
| GT201500247A (es) | Imidazopiridazinas sustituidas | |
| GT201400261A (es) | Solicitud pct face nacional novedosas n-piridinil amidas ciclicas sustituidas como inhibidores de quinasa | |
| MX376115B (es) | Composiciones para el cuidado personal con dos fases benéficas. | |
| GT201300254A (es) | Triazolopiridinas | |
| CL2017001483A1 (es) | Formulación de relación fija de insulina glargina/lixisenatida | |
| PH12015501096A1 (en) | Composition for immediate and extended release | |
| MX2016008665A (es) | Derivado basado en 1,2-naftoquinona y metodo de preparacion del mismo. | |
| MX2017009849A (es) | Composiciones de profármaco de monometilfumarato. | |
| CL2015002466A1 (es) | Formulaciones de compuestos orgánicos | |
| CL2018001493A1 (es) | Nuevos derivados de fenilo | |
| CR20160016A (es) | Pirazolpiridinas sustituidas | |
| BR112017009289A2 (pt) | métodos de administrar composições de amantadina | |
| MX2017008983A (es) | Composición farmaceútica de sulfonamida. |