CS775282A2 - Zpusob vyroby novych ergolinovych derivatu - Google Patents

Zpusob vyroby novych ergolinovych derivatu

Info

Publication number
CS775282A2
CS775282A2 CS827752A CS775282A CS775282A2 CS 775282 A2 CS775282 A2 CS 775282A2 CS 827752 A CS827752 A CS 827752A CS 775282 A CS775282 A CS 775282A CS 775282 A2 CS775282 A2 CS 775282A2
Authority
CS
Czechoslovakia
Prior art keywords
ergolinovych
derivatu
zpusob vyroby
novych
vyroby novych
Prior art date
Application number
CS827752A
Other languages
English (en)
Other versions
CS232000B2 (en
Inventor
Luigi Bernardi
Aldemio Temperilli
Daniela Ruggieri
Giuliana Arcari
Patricia Salvati
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of CS775282A2 publication Critical patent/CS775282A2/cs
Publication of CS232000B2 publication Critical patent/CS232000B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS827752A 1981-11-06 1982-11-01 Manufacturing process of new ergoline derovatives CS232000B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8133631 1981-11-06

Publications (2)

Publication Number Publication Date
CS775282A2 true CS775282A2 (en) 1984-01-16
CS232000B2 CS232000B2 (en) 1985-01-16

Family

ID=10525712

Family Applications (1)

Application Number Title Priority Date Filing Date
CS827752A CS232000B2 (en) 1981-11-06 1982-11-01 Manufacturing process of new ergoline derovatives

Country Status (21)

Country Link
US (1) US4500712A (cs)
JP (1) JPS5885886A (cs)
AT (1) AT381091B (cs)
AU (1) AU553903B2 (cs)
BE (1) BE894927A (cs)
CA (1) CA1191841A (cs)
CH (1) CH650506A5 (cs)
CS (1) CS232000B2 (cs)
DE (1) DE3240727A1 (cs)
DK (1) DK494882A (cs)
FI (1) FI73214C (cs)
FR (1) FR2516083A1 (cs)
GB (1) GB2112382B (cs)
GR (1) GR77055B (cs)
IE (1) IE54327B1 (cs)
IL (1) IL67155A (cs)
IT (1) IT1205272B (cs)
NL (1) NL8204225A (cs)
SE (1) SE452884B (cs)
SU (1) SU1189347A3 (cs)
ZA (1) ZA828095B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
PH21123A (en) * 1983-04-28 1987-07-27 Erba Farmitalia Ergoline derivatives
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
DE3413657A1 (de) * 1984-04-09 1985-10-17 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergoline
GB2173189B (en) * 1985-02-21 1988-04-27 Maruko Pharmaceutical Co Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
GB8515528D0 (en) * 1985-06-19 1985-07-24 Erba Farmitalia Ergoline derivatives
DE3528584A1 (de) * 1985-08-06 1987-02-19 Schering Ag Neue 1-alkyl-ergolin-thioharnstoffderivate
DE3533672A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-substituierte ergolinderivate
DE3535930A1 (de) * 1985-10-04 1987-04-09 Schering Ag Neue 2-substituierte ergolinderivate
ES2162856T3 (es) * 1992-12-24 2002-01-16 Pharmacia & Upjohn Spa Derivados de ergolina serotoninergicos.
DE19832191A1 (de) * 1998-07-17 2000-01-27 Knoell Hans Forschung Ev Neuartige Ergolinamin-Derivate und ihre Verwendung
PT1401863E (pt) 2001-06-08 2009-07-23 Ipsen Pharma Análogos quiméricos da somatostatina-dopamina
WO2006104141A1 (ja) * 2005-03-29 2006-10-05 Shionogi & Co., Ltd. ３－プロペニルセフェム誘導体
US9777039B2 (en) 2012-11-01 2017-10-03 Ipsen Pharma S.A.S. Somatostatin analogs and dimers thereof
TWI523863B (zh) 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238211A (en) * 1966-03-01 Derhvatives of g-methyl and i,g-dimethyl ergolhne
AT258479B (de) * 1961-05-29 1967-11-27 Farmaceutici Italia Verfahren zur Herstellung von neuen Verbindungen aus der Klasse des D-6-Methyl- (und -1,6-Dimethyl)-8-amino-methyl-ergolins I
GB1005880A (en) * 1961-11-10 1965-09-29 Sandoz Ag Ergolene and ergoline derivatives
GB1138419A (en) * 1966-07-29 1969-01-01 Farmaceutici Italia Ergoline derivatives
CH507248A (de) * 1967-03-16 1971-05-15 Spofa Vereinigte Pharma Werke Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure
BR6915443D0 (pt) * 1969-07-18 1973-03-13 Farmaceutici Italia Processo para a preparacao de derivados de ergolina
US3966941A (en) * 1970-09-23 1976-06-29 Spofa United Pharmaceutical Works Composition for preventing lactation or pregnancy in mammals and the method for using the same
SE393615B (sv) * 1971-05-19 1977-05-16 Sandoz Ag Forfarande for framstellning av 6-metyl-8 beta-ureidometyl-ergolener
NL7416120A (nl) * 1973-12-21 1975-06-24 Farmaceutici Italia Werkwijze voor het bereiden van pyrimidinoami- nomethylergolinederivaten.
US3996228A (en) * 1973-12-21 1976-12-07 Societa' Farmaceutici Italia S.P.A. Pyrimidinoaminoethyl ergoline derivatives
GB1573621A (en) * 1976-01-02 1980-08-28 Sandoz Ltd Acylated 6-methyl-8a-amino-ergoline i compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
HU178396B (en) * 1978-03-20 1982-04-28 Vianova Kunstharz Ag Process for producing new 8-beta-hydrazion-methyl-ergoline-and -ergolene derivatives
DD138979A1 (de) * 1978-09-27 1979-12-05 Karlheinz Seifert Verfahren zur herstellung von acylthioharnstoffen mit ergolinstruktur
US4201862A (en) * 1979-03-16 1980-05-06 Eli Lilly And Company 2-Azaergolines and 2-aza-8(or 9)-ergolenes
DE3129714A1 (de) * 1981-07-23 1983-02-10 Schering Ag, 1000 Berlin Und 4619 Bergkamen Anti-psychotikum

Also Published As

Publication number Publication date
SU1189347A3 (ru) 1985-10-30
IE54327B1 (en) 1989-08-30
US4500712A (en) 1985-02-19
AT381091B (de) 1986-08-25
SE452884B (sv) 1987-12-21
GR77055B (cs) 1984-09-05
SE8206282L (sv) 1983-05-07
CH650506A5 (de) 1985-07-31
JPS5885886A (ja) 1983-05-23
IE822614L (en) 1983-05-06
FI73214C (fi) 1987-09-10
IT1205272B (it) 1989-03-15
FR2516083B1 (cs) 1984-05-25
GB2112382A (en) 1983-07-20
AU9009082A (en) 1983-05-12
DE3240727A1 (de) 1983-05-19
IL67155A (en) 1985-07-31
GB2112382B (en) 1985-03-06
IL67155A0 (en) 1983-03-31
FI73214B (fi) 1987-05-29
IT8224077A0 (it) 1982-11-04
AU553903B2 (en) 1986-07-31
SE8206282D0 (sv) 1982-11-04
CS232000B2 (en) 1985-01-16
NL8204225A (nl) 1983-06-01
CA1191841A (en) 1985-08-13
FI823727A0 (fi) 1982-11-01
ATA399682A (de) 1986-01-15
DK494882A (da) 1983-05-07
FI823727L (fi) 1983-05-07
BE894927A (fr) 1983-05-05
ZA828095B (en) 1983-09-28
FR2516083A1 (fr) 1983-05-13
JPS628433B2 (cs) 1987-02-23

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